|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Matrix Metalloproteinase-14 Is a Negative Prognostic Marker for Patients with Gastric Cancer显示文摘 | Liang He Dake Chu Xia Li Jianyong Zheng Shanhong Liu Jipeng Li Qingchuan Zhao Gang Ji | 2013 | Digestive Diseases and Sciences2013，，5： | 2 |
| 2 | Cyanostilbene-based near-infrared emissive platinum(Ⅱ) metallacycles for cancer theranostics显示文摘In this work,a near-infrared emissive dipyridyl ligand was synthesized and used to prepare three platinum(II)metallacycles with different shapes via metal-coordination-driven self-assembly with different platinum(II)precursors.These metallacycles were further used for both cell imaging and cancer therapy,offering a new type of theranostic agents towards cancer treatment. | Lingzhi Ma Tianfeng Yang Zeyuan Zhang Siping Yin Zhongxiao Song Wen Shi Dake Chu Yanmin Zhang Mingming Zhang | 2019 | Chinese Chemical Letters2019，30，11： | 1 |
| 3 | Injectable Self‑Healing Adhesive pH‑Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing显示文摘Endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)are well-established therapeutics for gastrointestinal neoplasias,but complications after EMR/ESD,including bleeding and perforation,result in additional treatment morbidity and even threaten the lives of patients.Thus,designing biomaterials to treat gastric bleeding and wound healing after endoscopic treatment is highly desired and remains a challenge.Herein,a series of injectable pH-responsive selfhealing adhesive hydrogels based on acryloyl-6-aminocaproic acid(AA)and AA-g-N-hydroxysuccinimide(AA-NHS)were developed,and their great potential as endoscopic sprayable bioadhesive materials to efficiently stop hemorrhage and promote the wound healing process was further demonstrated in a swine gastric hemorrhage/wound model.The hydrogels showed a suitable gelation time,an autonomous and efficient self-healing capacity,hemostatic properties,and good biocompatibility.With the introduction of AA-NHS as a micro-cross-linker,the hydrogels exhibited enhanced adhesive strength.A swine gastric hemorrhage in vivo model demonstrated that the hydrogels showed good hemostatic performance by stopping acute arterial bleeding and preventing delayed bleeding.A gastric wound model indicated that the hydrogels showed excellent treatment effects with significantly enhanced wound healing with type I collagen deposition,α-SMA expression,and blood vessel formation.These injectable self-healing adhesive hydrogels exhibited great potential to treat gastric wounds after endoscopic treatment. | Jiahui He Zixi Zhang Yutong Yang Fenggang Ren Jipeng Li Shaojun Zhu Feng Ma Rongqian Wu Yi Lv Gang He Baolin Guo Dake Chu | 2021 | Nano-Micro Letters2021，13，5： | 1 |
| 4 | Matrix metalloproteinase‐12 is associated with overall survival in Chinese patients with gastric cancer显示文摘 | Jianyong Zheng Dake Chu Desheng Wang Yongsheng Zhu Xiaoyin Zhang Gang Ji Haihong Zhao Guosheng Wu Jianjun Du Qingchuan Zhao | 2012 | J Surg Oncol2012，，7： | 1 |
| 5 | Notch1 Expression in Colorectal Carcinoma Determines Tumor Differentiation Status显示文摘 | Dake Chu Weizhong Wang Huahong Xie Yunming Li Guanglong Dong Chunsheng Xu Dongli Chen Jianyong Zheng Mengbin Li Zifan Lu Gang Ji | 2009 | Journal of Gastrointestinal Surgery2009，，2： | 1 |
| 6 | Decreased expression of NDRG1 in glioma is related to tumor progression and survival of patients显示文摘 | Boqian Sun Dake Chu Wei Li Xiaodan Chu Yunming Li Dun Wei Haiping Li | 2009 | Journal of Neuro - Oncology2009，，2： | 1 |
| 7 | High Level of Notch1 Protein is Associated with Poor Overall Survival in Colorectal Cancer显示文摘 | Dake Chu MD Yunming Li MD Weizhong Wang MM Qingchuan Zhao MD Jipeng Li MD Yuanyuan Lu MD Mengbin Li MD Guanglong Dong MD Hongwei Zhang MD Huahong Xie MD Gang Ji MD | 2010 | Annals of Surgical Oncology2010，，5： | 1 |
| 8 | Notch1 expression in colorectal carcino- ma determines tumor differentiation status 显示文摘 | Dake Chu Weizhong Wan | 2009 | Gastrointest Surg2009，13，2： | 1 |
| 9 | Emissive metallacages for biomedical applications显示文摘Owing to their appealing three-dimensional structures and tunable photophysical properties, emissive metallacages have been widely applied in recognition and sensing, adsorption and separation, catalysis, etc. Recently, the application of emissive metallacages in biomedical fields has emerged as a hot research topic, because multiple biological functionalities can be facilely integrated into metallacage-based platforms to deliver different functions. In this review, the applications of emissive metallacages in bio-imaging, delivery and cancer theranostics are systematically summarized. The dilemmas and challenges of metallacage-based biomedical materials are also raised at the end of this review. We hope this review would provide some guidance for the construction of novel emissive metallacages with biological functions, and further advance the development of emissive metallacages as biomedical materials. | Qian Feng Rongrong Li Tingting Gao Dake Chu Mingming Zhang | 2023 | Science China Chemistry2023，66，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员