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| 1 | Interventions to improve sarcopenia in cirrhosis: A systematic review显示文摘BACKGROUND Sarcopenia, i.e., muscle loss is now a well-recognized complication of cirrhosis and in cases of non-alcoholic fatty liver disease can contribute to accelerate liver fibrosis leading to cirrhosis. Hence, it is imperative to study interventions which targets to improve sarcopenia in cirrhosis.AIM To examine the relationship between interventions such nutritional supplementation, exercise, combined life style intervention, testosterone replacement and trans jugular intrahepatic portosystemic shunt(TIPS) to improve muscle mass in cirrhosis.METHODS We search PubMed, EMBASE and Cochrane between June-August 2018, without a limiting period and the types of articles(RCTs, clinical trial, comparative study)in adult patients with sarcopenia and cirrhosis. The primary outcome of interest was improvement in muscle mass, strength and physical function interventions mentioned above. In the screening process, 154 full text articles were included in the review and 129 studies were excluded.RESULTS We identified 24 studies that met review inclusion criteria. The studies were diverse in terms of the design, setting, interventions, and outcome measurements.We performed only qualitative synthesis of evidence due to heterogeneity amongst studies. Risk of bias was medium in most of the included studies and low quality of evidence showed improvement in the muscle mass, strength and physical function following aerobic exercise. 60% of the included studies on the nutritional intervention, 100% of the studies on testosterone replacement in hypogonadal men and trans-jugular portosystemic shunt were proved to be effective in improving sarcopenia in cirrhosis.CONCLUSION Although the quality of evidence is low, the findings of our systematic review suggest improvement in the sarcopenia in cirrhosis with exercise, nutritional interventions, hormonal and TIPS interventions. High quality randomized controlled trials needed to further strengthen these findings. | Maliha Naseer Erica P Turse Ali Syed Francis E Dailey Mallak Zatreh Veysel Tahan | 2019 | World Journal of Clinical Cases2019，7，2： | 8 |
| 2 | Epidemiology,determinants,and management of AIDS cholangiopathy:A review显示文摘Diseases of the liver and biliary tree have been described with significant frequency among patients with human immunodeficiency virus(HIV), and its advanced state, acquired immunodeficiency syndrome(AIDS). Through a variety of mechanisms, HIV/AIDS has been shown to affect the hepatic parenchyma and biliary tree, leading to liver inflammation and biliary strictures. One of the potential hepatobiliary complications of this viral infection is AIDS cholangiopathy, a syndrome of biliary obstruction and liver damage due to infection-related strictures of the biliary tract. AIDS cholangiopathy is highly associated with opportunistic infections and advanced immunosuppression in AIDS patients, and due to the increased availability of highly active antiretroviral therapy, is now primarily seen in instances of poor access to antiretroviral therapy and medication non-compliance. While current published literature describes well the clinical, biochemical, and endoscopic management of AIDS-related cholangiopathy, information on its epidemiology, natural history, and pathology are not as well defined. The objective of this review is to summarize the available literature on AIDS cholangiopathy, emphasizing its epidemiology, course of disease, and determinants, while also revealing an updated approach for its evaluation and management. | Maliha Naseer Francis E Dailey Alhareth Al Juboori Sami Samiullah Veysel Tahan | 2018 | World Journal of Gastroenterology2018，24，7： | 5 |
| 3 | 经皮神经电刺激治疗女性纤维肌痛疗效取决于最初30分钟显示文摘前期研究表明,经皮神经电刺激(transcutaneous electrical nerve stimulation, TENS)治疗1个月可缓解纤维肌痛(fibromyalgia, FM)女性运动诱发的疼痛和疲劳。该研究再次使用前期TENS治疗FM的研究数据,进行应答者分析,以明确TENS治疗缓解疼痛和疲劳的预测因素,并使用受试者工作特征曲线验证预测模型,确定治疗所需数量(number needed to treat, NNT)和危害所需数量(number needed to harm, NNH)。FM女性病人被随机分配到TENS治疗组、TENS假治疗组和未使用TENS组。随机分组后,受试者接受治疗/假治疗1个月,接着TENS假治疗组和未使用TENS组再接受TENS治疗1个月。预测模型使用TENS治疗组(n=103)数据构建,并用TENS假治疗组和未使用TENS组(n=155)在后继TENS治疗1个月后的数据进行验证。使用逻辑回归模型筛选受试者特征、疼痛和疲劳对TENS治疗的初始反应、睡眠和心理等,以确定其与疼痛或疲劳变化之间的关系。疼痛包括TENS治疗后疼痛初始反应和病人疼痛广泛指数(AUC为0.80;95%置信区间:0.73-0.87)。疲劳改善的预测因素包括对TENS治疗的初始反应、婚姻状况和睡眠障碍(AUC为0.67;95%置信区间:0.58-0.75)。疼痛和疲劳的NNT为3.3-5.3,NNH为20-100。若最初30分钟TENS治疗有效则该FM女性病人长期使用TENS有效,而且该模型得到了后继的临床验证。NNT和NNH的结果表明TENS对管理FM女性病人的疼痛和疲劳安全有效。 | 梅相阳(译) 冯智英(校) Vance CGT Zimmerman MB Dailey DL | 2021 | 中国疼痛医学杂志2021，27，11： | 4 |
| 4 | Permeation into but not across the cornea:Bioimaging of intact nanoemulsions and nanosuspensions using aggregation-caused quenching probes显示文摘Nanoemulsions(NEs) and nanosuspensions(NSs) show great potential in enhancing the ocular bioavailability of therapeutics through topical delivery. However, transocular fate of intact NEs and NSs is still inconclusive. In this study, an aggregation-caused quenching fluorescent probe is used to track precorneal retention and transocular transportation of intact NEs and NSs, while coumarin 6 is used to mimick the cargo. NEs show superior precorneal retention to NSs. Both the two types of nanocarriers can permeate into but not across the cornea. The smaller NEs(100 nm) permeate better into the cornea than the bigger ones(210 nm). Nanocarriers in the cornea serves as depots. The released cargo molecules can penetrate across the cornea and diffuse into the lens. Moreover, the conjunctiva-scleral route may be potential to deliver drugs to the back of the eye, In conclusion, the study provides useful tools and information in the field of transocular transportation of nanoparticles. | Dailei Liu Bo Wan Jianping Qi Xiaochun Dong Weili Zhao Wei Wu Yikang Dai Yi Lu Zhongjian Chen | 2018 | Chinese Chemical Letters2018，29，12： | 4 |
| 5 | Inversion of 3D density interface with PSO-BP method显示文摘BP( Back Propagation) neural network and PSO( Particle Swarm Optimization) are two main heuristic optimization methods,and are usually used as nonlinear inversion methods in geophysics. The authors applied BP neural network and BP neural network optimized with PSO into the inversion of 3D density interface respectively,and a comparison was drawn to demonstrate the inversion results. To start with,a synthetic density interface model was created and we used the proceeding inversion methods to test their effectiveness. And then two methods were applied into the inversion of the depth of Moho interface. According to the results,it is clear to find that the application effect of PSO-BP is better than that of BP network. The BP network structures used in both synthetic and field data are consistent in order to obtain preferable inversion results. The applications in synthetic and field tests demonstrate that PSO-BP is a fast and effective method in the inversion of 3D density interface and the optimization effect is evident compared with BP neural network merely,and thus,this method has practical value. | ZHANG Dailei ZHANG Chong | 2016 | Global Geology2016，19，1： | 3 |
| 6 | Glucagon-like peptide 1 and appetite显示文摘 | Megan J. Dailey Timothy H. Moran | 2012 | Trends in Endocrinology & Metabolism2012，，： | 2 |
| 7 | Edge detection of potential field data based on image processing methods显示文摘The conventional methods of edge detection can roughly delineate edge position of geological bodies,but there are still some problems such as low detection accuracy and being susceptible to noise interference.In this paper,three image processing methods,Canny,Lo G and Sobel operators are briefly introduced,and applied to edge detection to determine the edge of geological bodies.Furthermore,model data is built to analyze the edge detection ability of this image processing methods,and compare with conventional methods.Combined with gravity anomaly of Sichuan basin and magnetic anomaly of Zhurihe area,the detection effect of image processing methods is further verified in real data.The results show that image processing methods can be applied to effectively identify the edge of geological bodies.Moreover,when both positive and negative anomalies exist and noise is abundant,fake edge can be avoided and edge division is clearer,and satisfactory results of edge detection are obtained. | TAN Xiaodi ZHANG Dailei MA Guoqing | 2018 | Global Geology2018，21，2： | 2 |
| 8 | A Statistical Algorithm for Estimating Speed from Single Loop Volume and Occupancy Measurements显示文摘 | Dailey D J | 1999 | Transportation Research B1999，，33： | 1 |
| 9 | Chronic throidiris: a clinical and pathologic study of 354 patients显示文摘 | Lindsay S Dailey ME Eriedlander J | 1952 | Clin Endocrinal1952，12，4： | 1 |
| 10 | Modified polyethylenimines as non-viral gene delivery systems for aerosol gene therapy: investigations of the complex struc- ture and stability during air-jet and ultrasonic nebulization 显示文摘 | KLEEMANN E DAILEY L A ABDELHADY H G | 2004 | Controlled Release2004，100，3： | 1 |
| 11 | Comparison of resonance outcomes after pharyngeal flap and furlow double-opposing z-plasty for surgical management of velopharyngeal incompetence显示文摘 | Dailey SA Karnell MP Karnell LH | | 0，，01： | 1 |
| 12 | Dynamic interspinous process stabilization:Review of complications associated with the X-STOP device显示文摘 | Bowers C Amini A Dailey AT | | 0，，06： | 1 |
| 13 | Growth of human bronchial epithelial cells at an air-liquid interface alters the response to particle exposure显示文摘 | GHIO A J DAILEY L A SOUKUP J M | 2013 | Part Fibre Toxicol2013，10，1： | 1 |
| 14 | Lower severe hypoglycemia risk: insulin glargine versus NPH insulin in type 2 diabetes显示文摘 | Dailey G Strange P | 2008 | Am J Manag Care2008，14，1： | 1 |
| 15 | New strategies for baaal insnlin treament in type 2 diabetes melitius显示文摘 | Dailey G | 2004 | Clin Ther2004，26，： | 1 |
| 16 | Assessing glycemic control with self-monitoring of blood glucose and hemoglobin A^le measurements显示文摘 | George Dailey | 2007 | Mayo Clinic Proceed ings2007，82，2： | 1 |
| 17 | Ballistic labeling and dynamic imaging of astrocytes in organotypic hippocampal slice cultures显示文摘 | Benediktsson AM Schachtele SJ Green SH Dailey ME | 2005 | J Neurosci Methods2005，141，1： | 1 |
| 18 | Relation of the thyroid neoplasms to Hashimotors disease of the thyroid gland显示文摘 | Dailey ME Lindsay S Skahen R | 1955 | Arch Surg1955，10，3： | 1 |
| 19 | Lipid effects of glyburide/metformin tablets in patients with type 2 diabetes mellitus with poor glycemic control and dyslipidemia in an open-label extension study 显示文摘 | DAILEY GE 3RD MOHIDEEN P FIEDOREK F T | 2002 | Clin Ther2002，24，9： | 1 |
| 20 | Chronic throiditis:a clinical and pathologic study of 354 patients显示文摘 | Lindsay S Dailey ME Eriodlender J | 1952 | Clin Endoetinal1952，12，4： | 1 |
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