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| 1 | CONSORT 2010说明与详述:报告平行对照随机临床试验指南的更新显示文摘大量证据显示随机对照临床试验(randomised controlled trial,RCT)的报告质量不理想。报告不透明,则读者既不能评判试验结果是否真实可靠,也不能从中提取可用于系统综述的信息。最近的方法学分析表明,报告不充分和设计不合理与对治疗效果产生评价偏倚有关。这种系统误差对RCT损害严重,而RCT正是以其能减少或避免偏倚而被视为评价干预措施的金标准。为了提高RCT的报告质量,一个由专家和编辑组成的工作组制定了临床试验报告的统一标准(Consolidated Standards of Reporting Trials,CONSORT)声明。CONSORT声明于1996年首次发表,并于2001年更新。声明由对照检查清单和流程图组成,供作者在报告RCT时使用。许多核心医学期刊和主要国际性编辑组织都已认可CONSORT声明。该声明促进了对RCT的严格评价和解释。2001年,在对CONSORT进行修订时,人们就已经清楚地认识到,解释和说明制定CONSORT声明的原理,有助于研究人员等撰写或评价临床试验报告。一篇CONSORT说明与详述文章于2001年同2001版CONSORT声明一起发表。2007年1月的专家会议之后,对CONSORT声明作了进一步修订并已发表,即'CONSORT2010声明'。这次更新对原版对照检查清单作了文字上的修改,使其更为明晰,并收入了与一些新近才认识到的主题相关的建议,如选择性报告结局产生的偏倚。说明与详述文件旨在加强人们对CONSORT声明的理解、应用和传播,这次也作了大量修订,对每一项新增或更新的清单条目的含义和增改理由进行了解释,提供了优秀的报告实例,还尽可能地提供了相关的经验性研究的参考文献。文中收入了若干流程图实例。'CONSORT2010声明'、其说明与详述文件,以及相关网站(www.consort-statement.org),对于改进随机临床试验报告必将有所裨益。 | David Moher Sally Hopewell Kenneth F Schulz Victor Montori Peter C Gφtzsche P J Devereaux Diana Elbourne Matthias Egger Douglas G Altman 周庆辉 卞兆祥 刘建平 | 2010 | 中西医结合学报2010，8，8： | 318 |
| 2 | 加强流行病学中观察性研究报告质量(STROBE)声明:观察性研究报告规范显示文摘很多生物医学研究都是观察性的。但对这类研究的报告却通常不完整,从而限制了对其优缺点及普适性的评价。“加强流行病学中观察性研究报告质量(STROBE)”工作组针对一篇完整明确的观察性研究报告应包括的内容提供了一套建议。建议涵盖了流行病学研究的三种主要设计类型:队列设计、病例对照设计和横断面设计。2004年9月,我们召开了为期2天的研讨会,与会的方法学专家、研究人员和期刊编辑共同起草了一份观察性研究报告应纳入的条目清单草案。此后,又通过协调小组数次会议及与有关人员电子邮件讨论等对该草案进行了修改,纳入了经验性证据和方法学方面的意见。通过研讨会及之后反复的咨询和修订,我们制定出了一个包含22个条目的清单(STROBE声明),分为论文的题目、摘要、引言、方法、结果和讨论等部分。其中18个条目适用于所有三种主要的观察性研究设计,其余4个条目则专门用于队列、病例一对照或横断面设计。详细的解释和示范文件已另行发表,在《公共科学图书馆一医学》(PLoS Medicine)、《内科学年报》(Annalsof Internal Medicine)和《流行病学》(Epidemiology)的网站可以免费获得。我们希望STROBE声明能有助于改善观察性研究报告的质量。 | Erikvon Elm Douglas G Altman Matthias Egger Stuart J Pocock Peter C G tzsche Jan P Vandenbroucke 赵乐(译) 邹光勇(审) 杜怀东(审) | 2008 | 世界临床医学2008，2，1： | 12 |
| 3 | Reuse of liver grafts following the brain death of the initial recipient显示文摘AIM: To determine if there is a reasonable prospect of success of a re-use liver transplantation.METHODS: We systematically searched for reports of liver graft re-use using electronic searches of PubMed and Web of Knowledge. We performed hand searches of references lists of articles reporting re-use of grafts.RESULTS: A systematic review of the literature reveals 28 liver transplantations using previously transplanted grafts. First and second recipients ranged in age from 4 to 72 years and 29 to 62 years respectively. Liver disease in the first recipient was varied including 5(18%) patients with fulminant liver failure who died subsequently of cerebral edema. The second transplanta-tion was performed after a median interval of 5 d(one day-13 years). Viral hepatitis was present in 3(11%) of the initial recipients and in 8(29%) of final recipients. Hepatocellular carcinoma was present in 6(21%) of the final recipients. Early survival after the final transplantation was 93%, whereas long-term survival was 78% with a mean follow-up of 23.3(3-120) mo.CONCLUSION: Outcomes of transplantation using previously transplanted grafts in this select population are similar to those seen with conventional grafts. | Hideaki Tanaka Vivian C McAlister Mark A Levstik Cameron N Ghent Paul J Marotta Douglas Quan William J Wall | 2014 | World Journal of Hepatology2014，6，6： | 3 |
| 4 | Label-retaining liver cancer cells are relatively resistant to sorafenib显示文摘 | Hong-Wu Xin Chenwi M Ambe Danielle M Hari Gordon W Wiegand Tyler C Miller Jin-Qiu Chen Andrew J Anderson Satyajit Ray John E Mullinax Tomotake Koizumi Russell C Langan Douglas Burka Michelle A Herrmann Paul K Goldsmith Alexander Stojadinovic Udo Rudloff S | 2013 | Gut2013，，12： | 2 |
| 5 | Predictors of progression in Barrett’s esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression显示文摘 | Brian J Reid Laura J Prevo Patricia C Galipeau Carissa A Sanchez Gary Longton Douglas S Levine Patricia L Blount Peter S Rabinovitch | 2001 | The American Journal of Gastroenterology2001，，10： | 2 |
| 6 | The modified method of charawith adjusted advection显示文摘 | Douglas J J r Huang C S Pereira F | 1999 | Numer Math1999，83，： | 2 |
| 7 | Human RhoGAP domain- containing proteins: structure, function and evolutionary relation- ships显示文摘 | Peck J Douglas G 4th Wu C H | 2002 | FEBS Lett2002，528，13： | 1 |
| 8 | Toward an Integrative Theory of Counterproductive Workplace Behavior:A Causal Reasoning Perspective显示文摘 | MARTINKO M J GUNDLACH M J DOUGLAS S C | 2002 | International Journal of Selection and Assessment2002，10，12： | 1 |
| 9 | An accelerated domain decomposition procedure based on Robin transmission conditions显示文摘 | DOUGLAS J J HUANG C S | 1997 | BIT1997，37，： | 1 |
| 10 | Two Divergent Members of a Tobacco 4-Coumarate: Coenzyme A Ligase (4CL) Gene Family (cDNA Structure, Gene Inheritance and Expression, and Properties of Recombinant Proteins) 显示文摘 | Lee D Douglas C J | 1996 | Plant physiology1996，112，1： | 1 |
| 11 | 显示文摘 | PILIEGO C HOLCOMBE T W DOUGLAS J D | 2010 | J Am Chem Soc2010，132，22： | 1 |
| 12 | Autoinduction of the trefoil factor 2 (TFF2) promoter requires an upstream cis -acting element显示文摘 | Clemens J Bulitta John V Fleming Raktima Raychowdhury Douglas Taupin Ian Rosenberg Timothy C Wang | 2002 | Biochemical and Biophysical Research Communications2002，，1： | 1 |
| 13 | Spinodal dewetting of thin polymer films 显示文摘 | Xie R Karim A Douglas J F Han C C Weiss R A | 1998 | Physical Review Letters1998，81，： | 1 |
| 14 | Resultsfrom the 1995 national college health risk behavior survey显示文摘 | Douglas K A Collins J L Warren C | 1997 | J Am College Health1997，46，2： | 1 |
| 15 | The association between anti-Mtlllerian hormone and IVF pregnancy outcomes is influenced by age 显示文摘 | Wang J G Douglas N C Nakhuda G S | 2010 | Reprod Biomed Online2010，21，6： | 1 |
| 16 | Identity of viridans streptococci isolated from cases of infective endocarditis 显示文摘 | DOUGLAS C W HEATH J HAMPTON K K | 1993 | J Med Microbiol1993，39，3： | 1 |
| 17 | Accelerated domain decomposition iterative procedures for mixed methods based on Robin transmission conditions显示文摘 | DOUGLAS J J HUANG C S | 1998 | Calcolo1998，35，： | 1 |
| 18 | Chromoplasts ultrastructure and estimated carotene content in root secondary phloem of different carrot varieties显示文摘 | KIM J E RENSING K H DOUGLAS C J | 2010 | Planta2010，231，3： | 1 |
| 19 | Anti-microbial action of melanocortin peptides and identification of a novel X-Pro-D/L-Val sequence in Gram-positive and Gram-negative bacteria显示文摘 | CHARNLEY M MOIR A J DOUGLAS C W | 2008 | Peptides2008，29，6： | 1 |
| 20 | A novel tuning strategy for multi variable model predictive control 显示文摘 | RAHUL S DOUGLAS J C | 1998 | ISA Transactions1998，36，4： | 1 |
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