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| 1 | FTIR Spectroscopic Studies on Molecular Interaction between Alcohols and N,N-dimethylacetamide显示文摘The association between alcohols and N,N-dimethylacetamide in carbon tetrachloride was investigated using FTIR spectroscopy at 298 K.The formation constants for 1∶1 and 1∶2 complexes were calculated using the method of Whetsel and Kagarise.The observed 1∶1 complex values were also verified using the method of Nash.The rate of change in C=O bond moment on complexing with alcohols increased with increasing acidity of alcohols.The formation constant and values of free energy change increased with the increase in carbon chain length of alcohols,which suggested that the degree of complex formation varied with the length of the carbon chain of alcohols. | SIVAGURUNATHAN P RAMACHANDRAN K DHARMALINGAM K | 2007 | 物理化学学报2007，23，3： | 2 |
| 2 | Expression of innate and adaptive immune mediators in human corneal tissue infected with Aspergillus or fusarium显示文摘 | Karthikeyan RS Leal SM Jr Prajna NV Dharmalingam K Geiser DM Pearlman E Lalitha P | | 0，，06： | 1 |
| 3 | Liraglutide:A review of its therapeutic use as a once daily GLP-1 analog for the management of type 2 diabetes mellitus显示文摘 | DHARMALINGAM M SRIRAM U BARUAH M P | | 0，，01： | 1 |
| 4 | Liraglutide:A review of its therapeutic use as a once daily GLP 1 analog for the manage ment of type 2 diabetes mellitus显示文摘 | Dharmalingam M Sriram U Baruah M P | 2011 | Indian J Endocrinol and Metab2011，15，1： | 1 |
| 5 | Optimization of cellular layout under dynamic demand environment by simulated annealing显示文摘 | DHARMALINGAM P KANTHAVEL K SATHIYAMOO- RTHY R | 2012 | International Journal of Science Engineering Research2012，3，10： | 1 |
| 6 | Fabrication and characterization of polymethylmethacrylate /poly- sulphone/beta-tricalcium phosphate composite for or- thopaedic applications显示文摘 | Bhat KA Rajangam P Dharmalingam S | 2012 | J Mater Sci2012，47，： | 1 |
| 7 | Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/beta-catenin/GSK-3beta signaling显示文摘 | Pandurangan A K Dharmalingam P Sadagopan S K | 2013 | J Environ Pathol Toxicol Oncol2013，32，： | 1 |
| 8 | Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/β-catenin/GSK-3β signaling显示文摘 | Pandurangan AK Dharmalingam P Sadagopan SK | 2013 | J Environ Pathol Toxicol Oncol2013，32，2： | 1 |
| 9 | Separa-tion of heavy metals from water samples using anion exchange polymers by adsorption process显示文摘 | RAJANGAM V RAJANGAM P DHARMALINGAM S | | 0，，2： | 1 |
| 10 | Lymphocytic hy-pophysitis masquerading as pituitary adenoma显示文摘 | Mittal R Kalra P Dharmalingam M | 2012 | Indian J Endoerinol Metab2012，16，2： | 1 |
| 11 | Luteolin,a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling显示文摘 | Pandurangan A K Ananda Sadagopan S K Dharmalingam P | 2014 | Toxicology Mechanisms and Methods2014，24，1： | 1 |
| 12 | Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/β-catenin/GSK-3β signaling显示文摘 | Pandurangan A K Dharmalingam P Sadagopan S K | 2013 | Journal of Environmental Pathology Toxicology and Oncology2013，32，2： | 1 |
| 13 | Molecularinteraction studies of acrylic esters with 1-alcohols显示文摘 | Sivagurunathan P Dharmalingam K Ramachandran K | 2006 | Spectrochimica Acta Part A Molecular&BiomolecularSpectroscopy2006，64，1： | 1 |
| 14 | Effect of luteolin on the levels of glycoproteins during azoxymethane - induced colon carcinogenesis in mice显示文摘 | Pandurangan A K Dharmalingam P Anandasadagopan S | 2012 | Asian Pac J Cancer Prev2012，13，4： | 1 |
| 15 | 复杂性区域疼痛综合征病人自身抗体在体外诱导内皮细胞促炎作用和功能紊乱显示文摘复杂性区域疼痛综合征(complex regional pain syndrome,CRPS)是一种肢体创伤后局部反应不足从而导致严重疼痛以及患肢自主神经和营养变化的综合征。针对人β2肾上腺素能受体和毒蕈碱M2受体的自身抗体(hβ2AR和hM2R)既往在CRPS病人中被描述过。该研究分析了CRPS病人的血清中针对hβ2AR、hM2R和内皮细胞的自身抗体,并研究了来自13名CRPS病人的纯化IgG对内皮细胞的功能影响。健康对照组11例,无CRPS的桡骨骨折病人7例和外周动脉血管疾病病人10例作为对照组。CRPS-IgG与内皮细胞表面结合(P<0.001),与hβ2AR和hM2R结合(P<0.05),后通过添加β2AR和M1R拮抗剂逆转。CRPS-IgG导致细胞毒性增加和内皮细胞增殖率降低,并且通过添加特异性拮抗剂,作用被中和。关于第二信使途径,CRPS-IgG诱导ERK1/2,p38和STAT1磷酸化,而AKT磷酸化在蛋白质水平上降低。此外,CRPS-IgG诱导黏附分子(ICAM-1和VCAM-1)在mRNA水平上的表达增加,从而诱导内皮细胞的促炎状况。该研究结果表明,CRPS病人不仅会产生针对hβ2AR和hM2R的自身抗体,而且这些自身抗体还会干扰内皮细胞在体外诱导hβ2AR和hM2R的功能效应,因此这可能是CRPS的病理生理学原因之一。 | Dharmalingam B Singh P Schramm P 慎紫玉(译) 郑拥军(校) | 2023 | 中国疼痛医学杂志2023，29，6： | 0 |
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