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| 1 | Is cardiac resynchronisation therapy feasible, safe and beneficial in the very elderly?显示文摘ObjectiveTo evaluate 心脏的同一时刻治疗(CRT ) 培植是否与经历 CRT 培植的 symptoms.MethodsConsecutive 病人一起在 octogenarians 和协会可行、安全,从二个英国中心被招募。根据年龄组织的病人:<80 &≥80 年。基线人口分布,复杂并发症和结果在 439 个病人的那些 groups.ResultsA 总数之间被比较在这研究, 26%≥ 是谁被包括;80 年。Octogenarians 更经常与心脏的同一时刻治疗使用高压脉冲来消减心脏相比收到了心脏的再同步治疗心律调整器。从心律调整器的升级在两个组是普通的(16%<80 年对 22%≥80 年, P = NS ) 。合作病态在两个组是同样普通的(全面糖尿病:25% , atrial 纤维性颤动:23% ,高血压:45%) 。更耐心的年龄 ≥80 年有重要的长期的肾疾病(CKD,估计的 glomerular 过滤率 <45 mL/min 每 1.73 m 2,44% 对 22% , P <0.01 ) 。全面复杂并发症率(任何东西) 在两个组是类似的(16% 对 17% , P = NS ) 。两个组表明了征兆的利益。一个年死亡率作为与更年轻的队相比是在 octogenarians 更大的几乎四褶层(13.9% 对 3.7% , P <0.01 ).ConclusionsCRT 看起来安全在尽管有广泛的合作病态老、特别地经常严重 CKD。征兆的改进看起来有意义。增加的策略是 CRT 的潜在的候选人的有 CHF 的老病人的适当鉴定被要求。 | Bartosz Olechowski Rebecca Sands Donah Zachariah Neil P Andrews Richard Balasubramaniam Mark Sopher John Paisey Paul R Kalra | 2015 | Journal of Geriatric Cardiology2015,12,5: | 5 |
| 2 | Association of NFKB1 gene polymorphism (rs28362491) with levels of inflammatory biomarkers and susceptibility to diabetic nephropathy in Asian Indians显示文摘AIM To investigate the association of NFKB1 gene-94 ATTG insertion/deletion(rs28362491) polymorphism with inflammatory markers and risk of diabetic nephropathy in Asian Indians.METHODS A total of 300 subjects were recruited(100 each), normoglycemic,(NG); type 2 diabetes mellitus(T2DM) without any complications(DM) and T2 DM with diabetic nephropathy [DM-chronic renal disease(CRD)]. Analysis was carried out by polymerase chain reaction-restriction fragment length polymorphism and ELISA. Pearson's correlation, analysis of variance and logistic regression wereused for statistical analysis.RESULTS The allelic frequencies of-94 ATTG insertion/deletion were 0.655/0.345(NG), 0.62/0.38(DM) and 0.775/0.225(DM-CRD). The-94 ATTG ins allele was associated with significantly increased levels of urinary monocyte chemoattractant protein-1(u MCP-1); u MCP-1(P = 0.026) and plasma tumor necrosis factor-alpha(TNF-α); TNF-α(P = 0.030) and almost doubled the risk of diabetic nephropathy(OR = 1.91, 95%CI: 1.080-3.386, P = 0.025).CONCLUSION-94 ATTG ins/ins polymorphism might be associated with increased risk of developing nephropathy in Asian Indian subjects with diabetes mellitus. | Amar Gautam Stuti Gupta Mohit Mehndiratta Mohini Sharma Kalpana Singh Om P Kalra Sunil Agarwal Jasvinder K Gambhir | 2017 | World Journal of Diabetes2017,8,2: | 4 |
| 3 | Surgical treatment of venous ulcers:role ofsubfascial endoscopic perforator vein ligation显示文摘 | Kalra M Glovisxki P | 2003 | SCAN2003,83,3: | 1 |
| 4 | Central administration of antisense oligodeoxynucleotides to neuropeptide Y(NPY) mRNA reveals the critical role of newly synthesized NPY in regulation of LHRH release显示文摘 | Kalra P S Bonavera J J Kalra S P | 1995 | Regul Pept1995,59,2: | 1 |
| 5 | Rapid improvement in cortical neuronal integrity in amyotrophic lateral sclerosis detected by proton magnetic resonance spectroscopic imaging显示文摘 | Kalra S Tai P Genge A | 2006 | J Neurol2006,253,8: | 1 |
| 6 | Central administration of antisense oligodeoxynucleotides to neuropeptide Y (NPY) mRNA reveals the critical role of newly synthesized NPY in regulation of LHRH release 显示文摘 | Kalra P S Bonavera J J Kalra S P | 1995 | Regulatory Peptides1995,59,2: | 1 |
| 7 | Liver of the 'visible man' 显示文摘 | Fasel JH Gingins P Kalra P | 1997 | Clin Anat1997,10,6: | 1 |
| 8 | Orexins, a novel family of hypothalamie neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner 显示文摘 | Pu S Jain M R Kalra P S | 1998 | Regulatory Peptides1998,78,: | 1 |
| 9 | Surgical treatment of venous:role of subfascial endoscopic perforator vein ligation显示文摘 | Kalra M Goviszki P | | 0,,03: | 1 |
| 10 | Haemoglobin concentration and prognosis in new cases of heart failure显示文摘 | Kalra P R Collier T Cowie M R | | 0,,9379: | 1 |
| 11 | Superficial vein surge)' and SEPS for chronic venous insufficiency显示文摘 | Puggioni A Kalra M Gloviczki P | 2005 | Semin Vase Surg2005,18,1: | 1 |
| 12 | Methylation status of MGMT gene promoter in meningiomas 显示文摘 | de Robles P Mcintyre J Kalra S | 2008 | Cancer Genet Cytogenet2008,187,: | 1 |
| 13 | Risk factors for early onset severe pre-eclampsia and eclampsia among north Indian women显示文摘 | Nanjundan P Bagga R Kalra J K | 2011 | Journal of Obstetrics and Gynaecology2011,31,5: | 1 |
| 14 | Reducing abdominal CT radiation dose with adaptive statistical iterative reconstruction technique显示文摘 | Prakasb P Kalra MK Kambadakone AK | 2010 | Invest Radiol2010,45,: | 1 |
| 15 | Bone marrow abnormalities in HIV disease显示文摘 | TRIPATHI A K MISRA R KALRA P | 2005 | J Assoc Physicians India2005,53,: | 1 |
| 16 | Nutritional infertility: the role of the interconnected hypothalamic neuropeptide Y-galanin-opioid network 显示文摘 | Kalra S P Kalra P S | 1996 | Frontiers Neuroendocrinology1996,17,4: | 1 |
| 17 | Effect of hemo-dialysis on cognitive function in ESRD patients显示文摘 | Madan P Agarwal S Kalra 0 P | 2007 | RenFail2007,29,: | 1 |
| 18 | Re- al time animation of realistic virtual humans显示文摘 | KALRA P MAGNENAT-THALMANN N MOCCOZET L | 1988 | Computer Graph- ics and Applications1988,19,5: | 1 |
| 19 | Radiation dose re- duction with chest computed tomography using adaptive statistical iterative reconstruction technique : initial experience 显示文摘 | Prakash P Kalra MK Digumarthy SR | 2010 | J Corn- put Assist Tomogr2010,34,1: | 1 |
| 20 | Imaging findings of per- icardia显示文摘 | Prakash P Kalra M K Stone J R | 2010 | J Comput Assist Tomogr2010,34,4: | 1 |