|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Sulforaphane as a Promising Natural Molecule for Cancer Prevention and Treatment显示文摘Tumorigenicity-inhibiting compounds have been identifled in our daily diet.For example,isothiocyanates(ITCs)found in cruciferous vegetables were reported to have potent cancer=prevention activities.The best characterized ITC is sulforaphane(SF).SF can simultaneously modulate multiple cellular targets involved in carcinogenesis,including(1)modulating carcinogen-metabolizing enzymes and blocking the action of mutagens;(2)inhibition of cell proliferation and induction of apoptosis;and(3)inhibition of neo-angiogenesis and metastasis.SF targets cancer stem cells through modulation of nuclear factor kappa B(NF-κB),Sonic hedgehog(SHH),epithelial-mesenchymal transition,and Wnt/βcatenin pathways.Conventional chemotherapy/SF combination was tested in several studies and resulted in favorable outcomes.With its favorable toxicological profile,SF is a promising agent in cancer prevention and/or therapy.In this article,we discuss the human metabolism of SF and its effects on cancer prevention,treatment,and targeting cancer stem cells,as well as providing a brief review of recent human clinical trials on SF. | Osama A.Elkashty Simon D.Tran | 2021 | Current Medical Science2021，41，2： | 4 |
| 2 | Use of light-emitting diode(LED)lamps in combination with metal halide(MH)lamps reduce fuel consumption in the Vietnamese purse seine fishery显示文摘The use of high-power lights during night-time purse seining is common in Vietnam.Typically,metal halide(MH)lamps are used in the commercial fishery to attract fish,however these lights require more energy,have a shorter lifespan,and lower chromatic performance than light emitting diode(LED)lamps.This study examined catch efficiency and fuel consumption when using LED lamps in combination with reduced numbers of MH lamps(10.24 kW),compared to conventional lighting(28.6 kW),used during purse seining off the coast of Ninh Thuan province,Vietnam.The economic performance associated with using LED lamps in this fishery was also assessed.We found no significant differences in catch rates between the different light treatments,however fuel consumption was significantly reduced.Fuel consumption per nightly trip using LED with MH lamps was 70.8 l(11.1 l/h)compared to114 l(17.45 l/hr)using MH lamps alone,an estimated 37.9%reduction in fuel consumption.An investment in LED lamps by a fishing enterprise will require additional initial costs,however our analysis revealed the financial break-event point can be reached after approximately 101 nightly trips when the fuel price is at the 2015 level of USD$0.74 per l.Fishing enterprises can increase their profitability,and reduce CO2 emissions,by using LED lamps in the Vietnamese purse seine fishery. | Khanh Q.Nguyen Phu D.Tran Luong T.Nguyen Phuong V.To Corey J.Morris | 2021 | Aquaculture and Fisheries2021，6，4： | 2 |
| 3 | Frequency-dependent dielectric constant prediction of polymers using machine learning显示文摘The dielectric constant(ϵ)is a critical parameter utilized in the design of polymeric dielectrics for energy storage capacitors,microelectronic devices,and high-voltage insulations.However,agile discovery of polymer dielectrics with desirableϵremains a challenge,especially for high-energy,high-temperature applications.To aid accelerated polymer dielectrics discovery,we have developed a machine-learning(ML)-based model to instantly and accurately predict the frequency-dependentϵof polymers with the frequency range spanning 15 orders of magnitude.Our model is trained using a dataset of 1210 experimentally measuredϵvalues at different frequencies,an advanced polymer fingerprinting scheme and the Gaussian process regression algorithm. | Lihua Chen Chiho Kim Rohit Batra Jordan P.Lightstone Chao Wu Zongze Li Ajinkya A.Deshmukh Yifei Wang Huan D.Tran Priya Vashishta Gregory A.Sotzing Yang Cao Rampi Ramprasad | 2020 | npj Computational Materials2020，，1： | 2 |
| 4 | Expression of the putative stem cell marker Musashi‐1 in Barrett’s esophagus and esophageal adenocarcinoma显示文摘 | Y. V.Bobryshev A. K.Freeman N. K.Botelho D.Tran A. J. M.Levert‐Mignon R. V. N.Lord | 2010 | Diseases of the Esophagus2010，，7： | 1 |
| 5 | Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China显示文摘 | Gina D.Tran Xiu‐DiSun Christian C.Abnet Jin‐HuFan Sanford M.Dawsey Zhi‐WeiDong Steven D.Mark You‐LinQiao Philip R.Taylor | 2004 | Int J Cancer2004，，3： | 1 |
| 6 | Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China显示文摘 | Gina D.Tran Xiu‐DiSun Christian C.Abnet Jin‐HuFan Sanford M.Dawsey Zhi‐WeiDong Steven D.Mark You‐LinQiao Philip R.Taylor | 2004 | Cancer2004，，3： | 1 |
| 7 | Hypogastric Arterial Selective and Superselective Embolization for Severe Postpartum Hemorrhage:A Retrospective Review of 36 Cases显示文摘 | C.Boulleret T.Chahid D.Gallot R.Mofid D.Tran Hai A.Ravel J.M.Garcier D.Lemery L.Boyer | | 0，，87： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员