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| 1 | Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats显示文摘AIM:To evaluate the therapeutic effects of a probiotic supplement(Clostridium butyricum,CGMCC0313)in a chemically-induced rat model of experimental colitis. METHODS:An experimental ulcerative colitis model was established by rectal injection of oxazolone into the colon of 40 Wistar rats randomly divided into four groups.The positive control group was sacrificed 3 d after colitis onset.The remaining groups were fed daily with either 2 mL of C.butyricum(2.3×1011 CFU/L), 2 mL of mesalamine(100 g/L),or 1 mL of sodium butyrate(50 mmol/L)for 21 d.The animals’body weight, behavior,and bowel movements were recorded weekly. After sacrifice,visual and microscopic observations of pathological changes of colon tissue were made,body weight and wet colon mass index were measured and recorded,and serum levels of interleukin-23(IL-23) and TNF-αwere measured using ELISA.Expression of calcitonin gene-related peptide in colon tissue was measured by RT-PCR.Finally,changes in rat intestinal microflora status were measured in all groups. RESULTS:We found that treatment with C.butyricum lowered the serum levels of both IL-23 and tumor necrosis factor-α(TNF-α)with similar or even better efficiency than that of mesalamine or sodium butyrate. The rat intestinal flora appeared to recover more quickly in the group treated with C.butyricum than in the mesalamine and sodium butyrate groups.Finally,we found that the expression level of calcitonin gene related peptide was elevated in colon tissue in the sodium butyrate treated group but not in the C.butyricum or mesalamine treated groups,indicating a sensitization of colon following sodium butyrate treatment.CONCLUSION:In our experimental colitis model, treatment with C.butyricum CGMCC0313,a probiotic supplement,is at least as efficient as treatment with mesalamine. | Hai-Qiang Zhang Tomas T Ding Jun-Sheng Zhao Xin Yang Hai-Xia Zhang Juan-Juan Zhang Yun-Long Cui | 2009 | World Journal of Gastroenterology2009，15，15： | 19 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 3 | Ex vivo expansion of hematopoietic stem cells derived from umbilical cord blood in rotating wall vessel显示文摘 | Liu Y Liu T Fan X Ma X Cui Z | 2006 | 中国生物学文摘2006，20，5： | 11 |
| 4 | Patterns of nestin expression in human skin显示文摘 | Wang Y Zhang Y Zeng Y Zheng Y Fu G Cui Z Yang T | 2006 | 中国生物学文摘2006，20，5： | 7 |
| 5 | EFFECT OF OVERLAPPING TREATMENT ON MICROSTRUCTURE OF LASER-CLAD WC/Ni60A COMPOSITE COATING显示文摘The effect of overlapping treatment on microstructure of laser clad WC/Ni60A composite coating was studied with XRD, SEM, TEM and SAED etc. The results show that during the overlapping treatment the existence of the residual heat and edge angle effect on the substrate has changed the composition and microstructure of the coating by raising the fusion temperature and increasing the dilution degree of the coating. | C.Z. Chen 1,2) , X.D. Liu 3) , S.J. Zhang 4) , D.W. Cui 1) , T.Q. Lei 2) and J.H. Yu 1) 1) College of Material Science and Technology, Shandong University of Technology, Jinan 250061, China 2) College of Material Science and T | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，5： | 6 |
| 6 | The ASIC Design for Synthesizing Dual Channel Gauss White Noise显示文摘 | Cui W Han Y Q Long T | 2002 | Chinese Journal of Electronics2002，11，3： | 2 |
| 7 | Doping and electrical transport in silicon nanowires显示文摘 | Cui Y Duan X F Hu J T | 2000 | J Phys Chem B2000，104，22： | 2 |
| 8 | The role of current limitations in Fowler–Nordheim electron emission from carbon films显示文摘 | Cui J B Teo K B K Tsai J T H | 2000 | Appl Phys Lett2000，77，： | 1 |
| 9 | Passivity analysis of integro-differential neural networks with time-varying delays显示文摘 | Lou X Y Cui B T | 2007 | Neurocomputing2007，70，： | 1 |
| 10 | Application of small angle neutron scattering to the in situ study of protein fouling on ceramic membranes 显示文摘 | Su T J Lu J R Cui Z R | 1998 | Langmuir1998，14，： | 1 |
| 11 | Fast Algorithm for Electromagnetic Scattering by Buried 3D Dielectric Objects of Large Size显示文摘 | Cui T J Chew W C | 1999 | IEEE Transactions on Geoscience and Remote Sensing1999，37，5： | 1 |
| 12 | A FAFFA-MLFMA algorithm for electromagnetic scattering 显示文摘 | Chew W C Cui T J Song J M | 2002 | IEEE Trans Antennas and Propagat2002，50，11： | 1 |
| 13 | Expression of p73 in colorectal carclnoma: clinicopathological relevance显示文摘 | Liu L Cui X Sakaguchi T | 2001 | J Int Med Res2001，29，4： | 1 |
| 14 | Molecular detection andsequence analysis of feline Torque teno virus(TTV)in China显示文摘 | ZHU C X SHAN T L CUI L | 2011 | Virus Res2011，156，12： | 1 |
| 15 | Estimates of equilibrium points and global asymptotic stability of Cohen-Grossberg neural networks with delays 显示文摘 | Qiu F Cui B T | 2009 | International Journal of Systems Science2009，40，11： | 1 |
| 16 | Dis-tribution Functions of a Simple Fluid under Shear:LowShear Rates显示文摘 | Kalyuzhnyi Y V Cui S T Cummings P T | 1999 | Phys Rev E1999，60，2： | 1 |
| 17 | Evaluation of three ornamental plants for phytoremediation of Pb-contamined soil显示文摘 | CUI S ZHANG T A ZHAO S L | 2013 | International Journal of Phytoremediation2013，15，4： | 1 |
| 18 | Apoptosis induced by the sonomechanical effects of low intensity pulsed ultrasound in a human leukemia cell line显示文摘 | Feril L B Jr Kondo T Cui Z G | | 0，，02： | 1 |
| 19 | Refractive error in urban and rural adult Chinese in Beijing显示文摘 | Xu L Li J Cui T | 2005 | Ophthalmology2005，112，10： | 1 |
| 20 | Identification and characterization of a novel Neospora caninum immune mapped protein 1显示文摘 | CUI X LEI T YANG D Y | 2012 | Parasitology2012，139，8： | 1 |
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