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380篇 您的检索式:作者名="Croft J"
    题名 作者 年代 出处 被引量
1p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson 2011Cell Research2011,21,4:3
2Assessment of stool color in commmunity management of prolonged jaundice in infancy 显示文摘Crofts D J Michel VJ Rigby AS 1999Acta Pediatr1999,88,9:1
3Targetto Target Interval Versus Probability Effects on P300 in One and Two-Tone Tasks显示文摘Croft R J C J Gonsalvez C Gabriel 2003Psychophysiology2003,40,3:1
4A randomized trial of\snonoperative treatment for perforated peptic ulcer显示文摘Croft T J Park K G Steele R J 1989N Engl J Med1989,320,15:1
5Equilibrium point control of a 2-DOF manipulator显示文摘Clapa D J Croft E A Hodgson A J 2006Journal of Dynamic Systems Measurement and Control2006,128,1:1
6Improvement in screening performance and diagnosis of congenital hypothyroid- ism in Scotland 1979-2003 显示文摘Jones JH Mackenzie J Croft GA 2006Arch Dis Child2006,91,8:1
7The GPⅠa C807T di-morphism associated with platelet collagen receptor density is nota risk factor for myocardial infarction显示文摘Croft S A Hampton K K Sorrell J A 1999Br J Haematol1999,106,3:1
8Hematocrit and risk of coronary heart disease mortality 显示文摘Brown D Giles W Croft J 2001Am Heart J2001,142,4:1
9Differences in the localization and morphology of chromosomes in the human nucleus显示文摘Croft J A Bridger J M Boyle S 1999J Cell Biol1999,145,:1
10Information Filtering and Information Retrieval:Two Sides of the Same Corn?显示文摘Belkin N J Croft W B 1992Communications of the ACM1992,12,:1
11FDG-PET imaging and the diagnosis of non-small cell lung cancer in a region of high histoplasmosis prevalence显示文摘CROFT DR TRAPP J KERNSTINE K 2002Lung Cancer2002,36,3:1
12The applicability of empiri- cal vegetation indices for determining leaf chlorophyU con- tent over different leaf and canopy structures显示文摘Croft H Chen J M Zhang Y 2014Ecologi- cal Complexity2014,17,1:1
13Target-to-target inter- val versus probability effects on P300 in one-and two-tone tasks 显示文摘Croft RJ Gonsalvez C J Gabriel C 2003Psychophysiology2003,40,3:1
14High-rate uncorrelated bit extraction for shared secret key generation from channel measurements显示文摘Patwari N Croft J Jana S 2010IEEE Transactions on Mobile Computing2010,9,1:1
15Role of p38 mitogen-actived protein kinase in cardiac myocyte secretion of the inflammatory cytokine TNF-α显示文摘Ballard -Croft CD White J David L 2001Am J Physiol Heart Cire Physiol2001,280,:1
16Secret key extraction from wireless signal strength in real environments 显示文摘PREMNATH S N JANA S CROFT J 2013I EEE Trans on Mo- bile Computing2013,12,5:1
17The Protein-sparing effect of carbohydrate 显示文摘Fuller M F Crofts R M J 1977British J Nutr1977,38,03:1
18Effects of vitamin C and vitamin E on in vivo lipid peroxidation : results of a randomized controlled trial 显示文摘Huang H Y Appel L J Croft K D 2002Am J Clin Nutr2002,76,3:1
19Total gastrectomy with extended lymphadenectomy for “curable” stomach cancer: experience in a non-Japanese Asian center显示文摘Nick Hayes Enders K.W Ng Simon A Raimes Trevor J Crofts Simon D.S Woods S.Michael Griffin S.C.Sydney Chung 1999Journal of the American College of Surgeons1999,,1:1
20Vitamin E in human health and disease显示文摘Clarke M W Burnett J R Croft K D 2008Critical Reviews in Clinical Laboratory Sciences2008,45,5:1
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