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| 1 | Intra-hepatic and extra-hepatic cholangiocarcinoma:New insight into epidemiology and risk factors显示文摘Cholangiocarcinoma(CCA) is a malignant tumour that arises from biliary epithelium at any portion of the biliary tree.CCA is currently classified as intra-hepatic or extra-hepatic CCA(EH-CCA).Recent evidences suggest that intra-hepatic CCA(IH-CCA) and EH-CCA are biologically different cancers,giving further support to a number of recent epidemiological studies showing large differences in terms of incidence,mortality and risk factors.The purpose of this manuscript is to review recent literature dealing with the descriptive epidemiology and risk factors of CCA with a special effort to compare IH-with EH-CCA. | Vincenzo Cardinale Rossella Semeraro Alessia Torrice Manuela Gatto Cristina Napoli Maria Consiglia Bragazzi Raffaele Gentile Domenico Alvaro | 2010 | World Journal of Gastrointestinal Oncology2010，2，11： | 12 |
| 2 | Cholangiocarcinoma: Update and future perspectives显示文摘 | Manuela Gatto Maria Consiglia Bragazzi Rossella Semeraro Cristina Napoli Raffaele Gentile Alessia Torrice Eugenio Gaudio Domenico Alvaro | 2010 | Digestive and Liver Disease2010，，4： | 2 |
| 3 | Descriptive epidemiology of cholangiocarcinoma in Italy显示文摘 | Domenico Alvaro Emanuele Crocetti Stefano Ferretti Maria Consiglia Bragazzi Riccardo Capocaccia | 2009 | Digestive and Liver Disease2009，，7： | 1 |
| 4 | Mito- chondrial defect and PGC-let dysfimction in parkin-associated familial Parkinson's disease显示文摘 | Consiglia Pacelli Domenico De Rasmo Anna Signorile | 2011 | Biochimica et Biophysica Acta(BBA) - Molec- ular Basis of Disease2011，1812，8： | 1 |
| 5 | Mitochondrial defect and PGC-1α dysfunction in parkin -associated familial Parkinson’s disease显示文摘 | Consiglia Pacelli Domenico De Rasmo Anna Signorile Ignazio Grattagliano Giuseppe di Tullio Andria D’Orazio Beatrice Nico Giacomo Pietro Comi Dario Ronchi Ermanno Ferranini Domenico Pirolo Peter Seibel Susanna Schubert Antonio Gaballo Gaetano Villani Tizia | 2011 | BBA - Molecular Basis of Disease2011，，8： | 1 |
| 6 | Descriptive epidemiology of cholangiocarcinoma in Italy显示文摘 | Domenico Alvaro Emanuele Crocetti Stefano Ferretti Maria Consiglia Bragazzi Riccardo Capocaccia | 2009 | Digestive and Liver Disease2009，，： | 1 |
| 7 | Cholangiocarcinoma: Epidemiology and risk factors 显示文摘 | Maria Consiglia Bragazzi Vincenzo Cardinale Guido Carpino | 2012 | Transl Gastroin- test Cancer2012，1，1： | 1 |
| 8 | Synthesis of activated cyclopropanes by an MIRC strategy:anenantioselective organocatalytic approach to spirocyclopropanes显示文摘 | Alessio R Sara M Consiglia T | 2011 | Eur J Org Chem2011，79，50： | 1 |
| 9 | Technology Innovation in Digital Architectural Processes显示文摘 | Consiglia Mocerino | 2016 | Journal of Civil Engineering and Architecture2016，10，8： | 0 |
| 10 | Integration of the Energy and Building Technologies显示文摘 | Consiglia Mocerino | 2016 | Journal of Civil Engineering and Architecture2016，10，12： | 0 |
| 11 | Interoperable Process: Efficient Systems in New Constructive and Product Performances显示文摘 | Consiglia Mocerino | 2017 | Journal of Civil Engineering and Architecture2017，11，5： | 0 |
| 12 | Melanocortin 3,5 receptors immunohistochemical expression in colonic mucosa of inflammatory bowel disease patients:A matter of disease activity?显示文摘BACKGROUND Melanocortin 3 and 5 receptors(i.e.,MC3R and MC5R)belong to the melanocortin family.However,data regarding their role in inflammatory bowel diseases(IBD)are currently unavailable.AIM This study aims to ascertain their expression profiles in the colonic mucosa of Crohn’s disease(CD)and ulcerative colitis(UC),aligning them with IBD disease endoscopic and histologic activity.METHODS Colonic mucosal biopsies from CD/UC patients were sampled,and immunohisto-chemical analyses were conducted to evaluate the expression of MC3R and MC5R.Colonic sampling was performed on both traits with endoscopic scores(Mayo endoscopic score and CD endoscopic index of severity)consistent with inflamed mucosa and not consistent with disease activity(i.e.,normal appearing mucosa).RESULTS In both CD and UC inflamed mucosa,MC3R(CD:+7.7 fold vs normal mucosa,P<0.01;UC:+12 fold vs normal mucosa,P<0.01)and MC5R(CD:+5.5 fold vs normal mucosa,P<0.01;UC:+8.1 fold vs normal mucosa,P<0.01)were significantly more expressed compared to normal mucosa.CONCLUSION MC3R and MC5R are expressed in the colon of IBD patients.Furthermore,expression may differ according to disease endoscopic activity,with a higher degree of expression in the traits affected by disease activity in both CD and UC,suggesting a potential use of these receptors in IBD pharmacology. | Antonietta Gerarda Gravina Iacopo Panarese Maria Consiglia Trotta Michele D'Amico Raffaele Pellegrino Franca Ferraraccio Marilena Galdiero Roberto Alfano Paolo Grieco Alessandro Federico | 2024 | World Journal of Gastroenterology2024，30，9： | 0 |
| 13 | Typologies of Intelligent Facades in Efficient Buildings显示文摘The production of efficient building models promotes the search for intelligent technologies,capable of making the car building sufficient,from an energy point of view,to improve the comfort and well-being of the occupants,while respecting the environment and the planet.So they need new building processes that increase market demand,enhancing the use of alternative sources in which construction becomes the focus of productivity.The objectives are those of energy self-sufficient buildings,with passive use of the roofs,in which the different materials and systems optimize the efficiency and effectiveness of the energy and technological systems,with an innovative constructive integrated design approach,for the new,for the redevelopment and recovery of the building,also according to European regulations including UNI EN 13830:2015 and other worldwide ones.The criteria are distinguished according to the needs of the occupants,for the use of energy self-sufficient environments,security,with air quality,living comfort,cost reduction and increased productivity of the real estate sector.The methodologies point to a new conscious and shared model for the use of innovative construction technologies,with BIM(Building Information Modeling)design and MEP(Mechanical,Electrical and Plumbing)systems,which aim at digitization with pre-planning and intelligent management in construction,and smart BMS(Building Management Systems)systems in the BA(Building Automation).So they use typologies of intelligent facades in efficient buildings,unitized curtain walling system,structural glass facades,suspended curtain-walls,etc.,with double and triple skin glazed systems,LED glass,with solar screens,etc.Therefore,high performance in passive systems,for natural lighting and ventilation,etc.is distinguished in envelopes in operation the solar incidence and solar carving techniques.The challenge is the well-being of the occupants in the use of innovative technologies for types of intelligent facades,in passive and efficient,low-carbon enclosures that interact with the user and the context,with a view to the durability of the systems,energy saving and some materials. | Consiglia Mocerino | 2020 | Journal of Civil Engineering and Architecture2020，14，6： | 0 |
| 14 | Sustainable Identities in the Technological Esprit of Architecture显示文摘 | Consiglia Mocerino | 2017 | Journal of Civil Engineering and Architecture2017，11，7： | 0 |
| 15 | Dynamism and Soft Robotics in the Intelligence of the New Design of Lightweight Envelopes显示文摘The innovation of building envelopes is densely characterized, in the new design process, by new products of the building industry and intelligent robotic systems, making them efficient and dynamic in an eco-efficient environmental context and spatial flexibility. The goal is that of energy efficiency and environmental sustainability that invest above all the building production sector, pushing towards a circular economy with the use of clean energy resources and new artificial intelligence systems. The intelligence is highlighted through the optimization of the performance of new lightweight envelopes, in the technological design and the new building process, through Lean planning and Lean construction, Mass customization, with application of criteria, methods and tools. So there are innovative technological solutions, for environmental comfort and energy saving, and typological solutions with high performance level, with the use of innovative, adaptive, advanced, light materials with nanoproducts, intelligent IT systems, etc. We highlight the effectiveness of design with natural passive use of renewable energy and energy efficiency of the envelope as “skin” and relative increase in performance levels, in the interaction with the internal environment and natural dynamic flows and in the conversion of thermal and electrical energy. The methodologies are aimed at the application of digital technologies and soft robotic systems for the management and quality of services with technological and constructive solutions for dynamic interactive envelope and intelligent systems of double or triple skin, curtain walls, etc. The challenge is new design models of dynamic enclosures, on criteria and methods that guide the new rules on energy efficiency in buildings, for environmental sustainability and housing quality with the integration of soft robots. | Consiglia Mocerino | 2019 | Journal of Civil Engineering and Architecture2019，13，3： | 0 |
| 16 | High Performance and Intelligence of Glass Technologies in Architecture显示文摘The new production models that aim at both the improvement of the various new processes and the existing ones,create new markets with innovative business methods and introduce sufficient technological solutions for the conversion and enhancement of electricity in construction.The objectives are of innovative glass technologies in the new building process with lean manufacturing,and robotic devices,follow criteria according to the needs of energy efficiency,energy saving,usability,reliability,thermo-hygrometric well-being,appearance,visual,acoustic well-being,reduction costs,safety of building systems and productivity.We highlight the strategic application of integrated design instrumentation and methodologies,digital fabrication,for intelligent,dynamic,adaptive and LED enclosures,BIPV(building integrated photovoltaics)with intelligent glass facades integrated with photovoltaic panels,with hybrid hydrogen systems and integration of RES(renewable energy sources)on the network,and their reliability.The criteria are for the use of clean energy with renewable resources.The challenge is new building models,with an increase in scientific support,in the application of intelligent glass technologies and in the efficient use of the various solutions that aim to reduce energy needs,with passive use of clean energy from RES. | Consiglia Mocerino | 2020 | Journal of Civil Engineering and Architecture2020，14，4： | 0 |
| 17 | The New Integrated Management of Efficient Buildings: An Intelligent Method Approach and AI显示文摘Building process innovation highlights building systems and products that denounce both an incremental and radical development,indicating the technological sector as the driver for energy efficiency.The prototypes of this innovation stand out both in the tertiary and residential sector and are aimed at sustainable development with the use of renewable resources,intelligent technologies,with a view to contextualizing and environmental energy requalification.The objectives are those of a new integrated building management,intended as an increase in energy efficiency and an efficient digitalized connection with users and smart grids,through control platforms,IoT(internet of things),security throughout the building’s life cycle and use of AI(artificial intelligence)devices and materials.The approach is a new methodology,with the application of BMS(building management system)and BEMS(building energy management system)systems integrated with other systems,with an interface of protocols open to different manufacturers and multiple functions that invest both the technological and environmental system of the building,with advantages in electrical energy management and thermoelectric like intelligent HVAC systems,with intelligent monitoring and user comfort.Both the new Artificial Intelligence and Machine Learning platforms contribute to a predictive use of energy efficiency with plant optimization.Therefore efficiency and energy saving strategies with intelligent integrated management and medium-long term maintenance programs.The challenge is a new intelligent method approach with the use of artificial intelligence and the development of new technologies in sustainable buildings. | Consiglia Mocerino | 2020 | Journal of Civil Engineering and Architecture2020，14，4： | 0 |
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