维普中文期刊产品整合服务
16篇 您的检索式:作者名="Conil S"
    题名 作者 年代 出处 被引量
1Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
2Linearity of the Atmospheric Response to North Atlantic SST and Sea Ice Anomalies 显示文摘CONIL S Li Z X 2005Journal of Climate2005,18,:1
3A 1000-year simulation with the IPSL ocean-atmosphere coupled model 显示文摘LI Z X CONIL S 2003Annals of Geophysics2003,46,:1
4Phase Itrial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopie total mesorectal excision(LTME) in rectal cancer patients 显示文摘Ugidos L Delgado S Conill C 2009Invest New Drugs2009,27,3:1
5The relative influence of soil moisture and SST in climate predictability explored within ensembles of AMIP type experiments显示文摘CONIL S DOUVILE H TYTECA S 2007Climate Dynamics2007,28,23:1
6Intramedullary spinal cord metastases of melanoma显示文摘Conill C Sanchez M Puig S 2004Melanoma Res2004,14,5:1
7The relative in- fluence of soil moisture and SST in climate pre- dictability explored within ensembles of AMIP type experiments显示文摘Conil S Douville H Tyteca S 2007Climate dynamics2007,28,23:1
8Ceftasidime dosage regimen in intensive care unit patients: from a population phar- macokinetic approach to clinical practice via Monte Carlo simu- lations显示文摘GEORGES B CONIL JM RUIZ S 2012Br J Clin Pharmacol2012,73,4:1
9Intrameduuary spinal cord metastases of melanoma 显示文摘Conill C Sanchez M Puig S 2004Melanoma Res2004,14,5:1
10The relative influence of soil moisture and SST in climate predictability explored within ensembles of AMIP type experiments显示文摘Conil S Douville H Tyteca S 2007Climate Dynamics2007,28,2:1
11The relative influence of soil moisture and SST in climate predictability explored within ensembles of AMIP type experiments显示文摘Conil S Douville H Tyteca S 2007Climate Dynam?ics2007,28,:1
12Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients显示文摘Lisardo Ugidos Salvadora Delgado Carlos Conill Angels Ginés Rosa Gallego Juan Ramón Ayuso Rosa Miquel Monica Tosca Antonio Lacy Antoni Castells Joan Maurel 2009Investigational New Drugs2009,,3:1
13Ceftazidime dosage regi men in intensive care unit patients: from a population pharma cokinetic approach to clinical practice via Monte Carlo simula tions显示文摘Georges B Conil JM Ruiz S 2012Brit J C1inPharm2012,73,58:1
14Notes and correspondence: Transient response of an atmosphere GCM to North atlantic SST anomalies显示文摘Li Z X and Conil S 2003Journal of Climate2003,16,:1
15Phase 显示文摘Ugidos L Delgado S Conill C 2009Invest New Drugs2009,27,3:1
16Wholebrain irradiation and temozolomide based chemotherapy inmelanoma brain metastases显示文摘Conill C Jorcano S Domingo-Domenech J 2006Clin Transl Oncol2006,8,4:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费