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| 1 | Towards an Artificial Intelligence Framework for Data-Driven Prediction of Coronavirus Clinical Severity显示文摘The virus SARS-CoV2,which causes the Coronavirus disease COVID-19 has become a pandemic and has spread to every inhabited continent.Given the increasing caseload,there is an urgent need to augment clinical skills in order to identify from among the many mild cases the few that will progress to critical illness.We present a first step towards building an artificial intelligence(AI)framework,with predictive analytics(PA)capabilities applied to real patient data,to provide rapid clinical decision-making support.COVID-19 has presented a pressing need as a)clinicians are still developing clinical acumen given the disease’s novelty,and b)resource limitations in a rapidly expanding pandemic require difficult decisions relating to resource allocation.The objectives of this research are:(1)to algorithmically identify the combinations of clinical characteristics of COVID-19 that predict outcomes,and(2)to develop a tool with AI capabilities that will predict patients at risk for more severe illness on initial presentation.The predictive models learn from historical data to help predict specifically who will develop acute respiratory distress syndrome(ARDS),a severe outcome in COVID-19.Our experimental results based on two hospitals in Wenzhou,Zhejang,China identify features most predictive of ARDS in COVID-19 initial presentation which would not have stood out to clinicians.A mild increase in elevated alanine aminotransferase(ALT)(a liver enzyme)),a presence of myalgias(body aches),and an increase in hemoglobin,in this order,are the clinical features,on presentation,that are the most predictive.Those two centers’COVID-19 case series symptoms on initial presentation can help predict severe outcomes.Predictive models that learned from historical data of patients from two Chinese hospitals achieved 70%to 80%accuracy in predicting severe cases. | Xiangao Jiang Megan Coffee Anasse Bari Junzhang Wang Xinyue Jiang Jianping Huang Jichan Shi Jianyi Dai Jing Cai Tianxiao Zhang Zhengxing Wu Guiqing He Yitong Huang | 2020 | Computers, Materials & Continua2020,,4: | 15 |
| 2 | Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models显示文摘 | Ryan B. Corcoran Katherine A. Cheng Aaron N. Hata Anthony C. Faber Hiromichi Ebi Erin M. Coffee Patricia Greninger Ronald D. Brown Jason T. Godfrey Travis J. Cohoon Youngchul Song Eugene Lifshits Kenneth E. Hung Toshi Shioda Dora Dias-Santagata Anurag Sin | 2013 | Cancer Cell2013,,: | 2 |
| 3 | Characterization of carbonaceous aerosols outflow from India and Arabia:Biomass/biofuel burning and fossil fuel combustion显示文摘 | GUAZZOTTI S A SUESS D T COFFEE K R | 2003 | Journal of Geophysical Research2003,108,: | 1 |
| 4 | Process in modeling pressure oscillations in regenerative liquid propellant guns显示文摘 | | 2000 | Journal of Propulsion and Power2000,16,2: | 1 |
| 5 | Phytoalexin production potential of grape berries显示文摘 | Creasy L L Coffee M | 1988 | J Amer Soc Hort Sci1988,113,2: | 1 |
| 6 | The DuPont model: Evaluating alternative strategies in the retail industry显示文摘 | Little P L Little B L Coffee D | 2009 | Academy of Strategic Management Journal2009,8,: | 1 |
| 7 | The PASS-Q: the per- ceived available support in sport questionnaire 显示文摘 | Freeman P Coffee P Rees T | 2011 | Jour- nal of Sport and Exercise Psychology2011,33,1: | 1 |
| 8 | ,The Future as History:The Prospects for Global Convergence in Corporate Governance and Its Implications显示文摘 | | 1999 | Northwestern University Law Review1999,93,3: | 1 |
| 9 | The Future As History-The Prospects of Global Convergence in Corporate Governance and its Implications显示文摘 | Coffee J | 1999 | Northwestern Law Review1999,,93: | 1 |
| 10 | Market Failure and the Economic Case for a Mandatory Disclosure System 显示文摘 | Coffee J C | 1984 | Virginia Law Re- view1984,70,: | 1 |
| 11 | Liquidity versus control: The institutional investor as corporate monitor 显示文摘 | Coffee J | 1991 | Columbia Law Review1991,,91: | 1 |
| 12 | Process in modeling pressure oscillations in regenerative liquid propellant guns显示文摘 | Coffee T P | 2000 | Journal of Propulsion and Power2000,16,2: | 1 |
| 13 | Endothelial dysfunction and eardiorenal injury in experimental salt-sensitive hypertension effects of antihypertensive therapy 显示文摘 | Hayakawa H Coffee K Raij L | 1997 | Circulation1997,96,7: | 1 |
| 14 | Racing towards the top? The impact of cross -listings and stock market competition on international corporate governance 显示文摘 | John C Coffee Jr | 2002 | Columbia Law Review2002,102,7: | 1 |
| 15 | Process in modeling pressure oscillations in regenerative liquid propellant guns显示文摘 | Coffee T P | 2000 | Journal of Propulsion and Power2000,16,2: | 1 |
| 16 | Mosaic FMR1 deletion causes fragile X syndrome and can lead to molecular misdiagnosis 显示文摘 | Coffee B Ikeda M Budimirovic DB | 2008 | Am J Med Genet A2008,146,10: | 1 |
| 17 | Privatization and Corporate Governance: The Lessons from Securities Market Failure 显示文摘 | Coffee J C | 1999 | Journal of Corporation Law1999,,25: | 1 |
| 18 | Liquidity versus control, the Institutional Investor as corporate monitor显示文摘 | Coffee J | 1991 | Columbia law Review1991,91,6: | 1 |
| 19 | Liquidity Versus Control:The institutional investorsas Corporate Monitors 显示文摘 | Coffee J | 1991 | Columbia law review1991,91,6: | 1 |
| 20 | Racing Towards the Top? The Impact of Cross - listings and Stock Market Competition on International Corporate Governance 显示文摘 | Coffee J | 2002 | Columbia Law Review2002,102,7: | 1 |