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	题名	作者	年代	出处	被引量
1	Abnormal endogenous pain modulation and somatic and visceral hypersensitivity in female patients with irritable bowel syndrome显示文摘AIM: To investigate the role of endogenous pain modulatory mechanisms in the central sensitization implicated by the visceral hypersensitivity demonstrated in patients with irritable bowel syndrome (IBS). Dysfunction of modulatory mechanisms would be expected to also result in changes of somatic sensory function. METHODS: Endogenous pain modulatory mechanisms were assessed using heterotopic stimulation and somatic and visceral sensory testing in IBS. Pain intensities (visua analogue scale, VAS 0-100) during suprathreshold recta distension with a barostat, cold pressor stimulation of the foot and during both stimuli simultaneously (heterotopic stimulation) were recorded in 40 female patients with IBS and 20 female healthy controls. RESULTS: Rectal hypersensitivity (defined by 95% CI of controls) was seen in 21 (53%), somatic hypersensitivity in 22 (55%) and both rectal and somatic hypersensitivity in 14 of these IBS patients. Heterotopic stimulation decreased rectal pain intensity by 6 (-11 to -1) in controls, but increased rectal pain by 2 (-3 to +6) in all IBS patients (P < 0.05) and by 8 (-2 to +19) in IBS patients with somatic and visceral hypersensitivity (P < 0.02). CONCLUSION: A majority of IBS patients had abnormal endogenous pain modulation and somatic hypersensitivity as evidence of central sensitization.	Clive H Wilder-Smith Joan Robert-Yap	2007	World Journal of Gastroenterology2007，13，27：	19
2	Toughening tetrafunctional epoxy resins using polyetherimide显示文摘	Clive B Bucknall Adrian H Gilbert	1989	Polymer1989，30，2：	1
3	Physical properties and stability of two emulsion formulations of propofol显示文摘	Jihong H Stanley SD Clive W	2001	International Journal of Pharmaceutics2001，，215：	1
4	Developing managerial learning styles in the context of the strategic application of information and communications technologies 显示文摘	CLIVE H NIGEL C	2001	International Journal of Training & Development2001，5，1：	1
5	Effect of morphine and tramadol on somatic and visceral sensory function and gastrointestinal motility after abdominal surgery显示文摘	Clive H Wild-Smith MD Lauren Hill		0，，03：	1
6	Postoperative analgesia: pain by choice? The influence of patient attitudes and patient education显示文摘	Clive H Wilder S Luzia S	1992	Pain1992，50，3：	1
7	Effect of eradication ofHelicobacter pylori infection on gastric epithelial cell proliferation显示文摘	Rachel J. Cahill MD H Xia MD PhD Clive Kilgallen MB Shona Beattie SRN Hilary Hamilton SRN Prof. Colm O’morain MD MSc FRCP	1995	Digestive Diseases and Sciences1995，，8：	1
8	Zinc-rich primers Ⅰ:design principles显示文摘	HARE CLIVE H		0，，07：	1
9	Impact of CK-MB testisg policies on hospital length of stay and laboratory costs for patients with myocardial infarction or chest pain显示文摘	Wu A H Clive J M	1997	Clin Chem1997，43，：	1
10	Cholinesterases: Roles in the brain during health and disease显示文摘	Ballard Clive G Greig Nigel H Guillozet-Bongaarts Angela L	2005	Current Alzheimer Research2005，2，3：	1
11	Particle image velocimetry analysis using an optically addressed spatial light modulator:effects of nonlinear transfer function显示文摘	Michael L J William J H Clive A G	1995	Applied Optics1995，34，11：	1
12	Toughening tetrafunctional epoxy resins using polyetherimide 显示文摘	Clive B Bueknall Adrian H Gilbert	1989	Polymer1989，30，2：	1
13	A dynamic light scattering investigation of nucleation and growth in supersaturated alkaline sodium aluminate solutions (synthetic Bayer liquors)显示文摘	DAMIEN R H ROLAND I K CLIVE A P	1999	Colloids and Surfaces A1999，154，3：	1
14	Calibration and comparison of chlorine decay models for a test water distribution显示文摘	STERAN H M ROGER S P CLIVE A W	2000	34(8) :2301 - 23092000，34，8：	1
15	Studies on the ability of a Pltamogeton pectinatus community to remove dissolved nitrogen and phosphorus compounds from lake water显示文摘	Clive H W	1981	Journal of Applied Ecology1981，18，2：	1
16	Piezoelectric properties in the perovskite BiScO3-PbTiO3-(Ba,Sr)TiO3 ternary system显示文摘	SONG T H RICHARD E THOMAS R CLIVE A WES H	2003	Japanese Journal of Applied Physics2003，42，：	1
17	Photoeradication of helicohacter pylori using 52 aminolevulinie acid : preliminary human studies 显示文摘	Clive H Wilder-Smith Petra Wilder-Smith Pierre Grosjean	2002	Lasers Surg and Med2002，31，1：	1
18	Ethanol and brain damage显示文摘	Clive H Izuru M	2005	Current Opinion in Pharmacology2005，5，：	1
19	The Montreal Cognitive Assessment:Validity and Utility in a Memory Clinic Setting显示文摘	Tasha S Nadia G Clive H	2007	The Canadian Journal of Psychiatry2007，52，：	1
20	Clinical examination, endosonogra- phy, and MR imaging in preoperative assessment of fistula in ano: comparison with outcome based reference standard显示文摘	GordonN Steve H Clive I	2004	Radiology2004，233，3：	1

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