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| 1 | Acute pancreatitis at the beginning of the 21st century: The state of the art显示文摘Acute pancreatitis is an acute inflammatory disease of the pancreas which can lead to a systemic inflammatory response syndrome with significant morbidity and mortality in 20% of patients. Gallstones and alcohol consumption are the most frequent causes of pancreatitis in adults. The treatment of mild acute pancreatitis is conservative and supportive; however severe episodes characterized by necrosis of the pancreatic tissue may require surgical intervention. Advanced understanding of the pathology, and increased interest in assessment of disease severity are the cornerstones of future management strategies of this complex and heterogeneous disease in the 21st century. | Alfredo F Tonsi Matilde Bacchion Stefano Crippa Giuseppe Malleo Claudio Bassi | 2009 | World Journal of Gastroenterology2009，15，24： | 54 |
| 2 | Helicobacter pylori infection and extragastric disorders in children: A critical update显示文摘Helicobacter pylori(H. pylori) is a highly prevalent, serious and chronic infection that has been associated causally with a diverse spectrum of extragastric disorders including iron deficiency anemia, chronic idiopathic thrombocytopenic purpura, growth retardation, and diabetes mellitus. The inverse relation of H. pylori prevalence and the increase in allergies, as reported from epidemiological studies, has stimulated research for elucidating potential underlying pathophysiological mechanisms. Although H. pylori is most frequently acquired during childhood in both developed and developing countries, clinicians are less familiar with the pediatric literature in the field. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae. A further clinical challenge is whether the progressive decrease of H. pylori in thelast decades, abetted by modern clinical practices, may have other health consequences. | Lucia Pacifico John F Osborn Valeria Tromba Sara Romaggioli Stefano Bascetta Claudio Chiesa | 2014 | World Journal of Gastroenterology2014，20，6： | 18 |
| 3 | Consequences of Helicobacter pylori infection in children显示文摘Although evidence is emerging that the prevalence of Helicobacter pylori (H. pylori) is declining in all age groups, the understanding of its disease spectrum continues to evolve. If untreated, H. pylori infection is lifelong. Although H. pylori typically colonizes the hu-man stomach for many decades without adverse con-sequences, children infected with H. pylori can manifest gastrointestinal diseases. Controversy persists regarding testing (and treating) for H. pylori infection in children with recurrent abdominal pain, chronic idiopathic thrombocytopenia, and poor growth. There is evidence of the role of H. pylori in childhood iron deficiency anemia, but the results are not conclusive. The possibility of an inverse relationship between H. pylori and gastroesophageal reflux disease, as well as childhood asthma, remains a controversial question. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae. | Lucia Pacifico Caterina Anania John F Osborn Flavia Ferraro Claudio Chiesa | 2010 | World Journal of Gastroenterology2010，16，41： | 11 |
| 4 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 5 | Ultrasound imaging of abdominal sarcoidosis: State of the art显示文摘Since it has been recognized that sarcoidosis(SA) is not an exclusive disorder of the lungs but can also affect other organs such as the liver and spleen, efforts have been made to define specific imaging criteria for the diagnosis of the single organ involvement, and the concept has been reinforced that the exclusion of alternative causes is important to achieve the correct diagnosis. Ultrasound(US)is a useful tool to evaluate patients with suspected abdominal SA, such as of the liver, spleen, kidney, pancreas and other organs, showing findings such as organomegaly, focal lesions and lymphadenopathy. While the diagnosis of abdominal SA is more predictable in the case of involvement of other organs(e.g.,lungs), the problem is more complex in the case of isolated abdominal SA. The recent use of contrast-enhanced ultrasound and endoscopic ultrasound elastography has provided additional information about the enhancement patterns and tissue rigidity in abdominal SA. Here we critically review the role of US in abdominal SA, reporting typical findings and limitations of current evidence and by discussing future perspectives of study. | Claudio Tana Cosima Schiavone Andrea Ticinesi Fabrizio Ricci Maria Adele Giamberardino Francesco Cipollone Mauro Silingardi Tiziana Meschi Christoph F Dietrich | 2019 | World Journal of Clinical Cases2019，7，7： | 2 |
| 6 | Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘 | Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli | 2011 | Lancet Oncology2011，，13： | 2 |
| 7 | Expression of cell cycle regulated proteins pRb2/pl30,p107,p27(kip1),p53,Mdm-2,and Ki-67(MIB-1)in prostatic gland adenocarcinoma显示文摘 | Claudio P P Zamparelli A Garcia F U | 2002 | Clin Cancer Res2002，8，6： | 1 |
| 8 | Self-cleaning test of doped TiO2-coated glass plates under solar exposure显示文摘 | Jorge M V Claudio F R Jorge R O | 2009 | Industrial & Engineering Chemistry Research2009，48，： | 1 |
| 9 | Participa- tion of vasoactive intestinal polypeptide in ovarian ster- oids production during the rat estrous cycle and in the development of estradiol valerate-induced polycystic ova- ry显示文摘 | Claudio Parra Jenny L F Leticia S Luna | 2007 | Biol Reprod2007，133，1： | 1 |
| 10 | ShortPath Evaporation for Methyl Chavicol Enrichment fromBasil Essential Oil显示文摘 | PATRICIA F M CLAUDIO C EDGAR L M | 2012 | Separation and Purification Technology2012，，87： | 1 |
| 11 | Design, Genera- tion, And Stress Analysis of Two Versions of Geometry of Face-Gear Drives 显示文摘 | Litvin F L Alfonso F Claudio Z | 2002 | Mechanism and Machine Theory2002，37，4： | 1 |
| 12 | Enzyme-catalysed approach to the preparation of the triazole antifungals:synthesis of(-)-genaconazole显示文摘 | Daniela A Elisabetta B Claudio F | 2009 | Tetrahedron:asymmetry2009，20，6： | 1 |
| 13 | Aqueous biphasic systems: a boost brought about by using ionic liquids 显示文摘 | Freire M G Claudio A F M Araujo J M M | 2012 | Chemical Society Reviews2012，41，14： | 1 |
| 14 | Extracting fuzzy if-then rules by using the information matrix technique显示文摘 | Huang C F Moraga Claudio | 2005 | Journal of Computer and System Sciences2005，70，1： | 1 |
| 15 | Performance modeling for contractor selection 显示文摘 | Luis F A Claudio M | 2002 | Journal of Management in Engineering2002，18，2： | 1 |
| 16 | The fuzzy clearing approach for a niching genetic algorithm applied to a nuclear reactor core design optimization problem显示文摘 | SACCO W F MARCELO D M CLAUDIO M N A | 2004 | An- nals of Nuclear Energy2004，31，1： | 1 |
| 17 | Coutinho critical assessment of the formation of ionic-liquid-based aqueous two-phase systems in acidic media显示文摘 | CLAUDIO A F M FERREIRA A M SHAHRIARI S FREIRE M G JOAO A P | 2011 | J Phys Chem B2011，115，11： | 1 |
| 18 | Plasticizers infant nutrition and reproductive health 显示文摘 | Giuseppe L Claudio D F Alberto V | 2004 | Reproductive Toxicology2004，19，1： | 1 |
| 19 | Face-gear drive with spur involute pinion: geometry, generation by a worm, stress analysis显示文摘 | Litvin F L Alfonso Fuentes Claudio Zanzi | 2002 | Computer Methods in Applied Mechanics and Engi- neering2002，191，2526： | 1 |
| 20 | De- sign, generation, and stress analysis of two versions of geometry of face -gear drives 显示文摘 | LITIVIN F L ALFONSO F CLAUDIO Z Z | 2002 | Mechanism and Ma- chine Theory2002，37，4： | 1 |
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