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| 1 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 2 | Comparative study of gas accumulations in the Permian Changxing reefs and Triassic Feixianguan oolitic reservoirs between Longgang and Luojiazhai-Puguang in the Sichuan Basin显示文摘Reef and oolitic gas reservoirs in the Permian Changxing and Triassic Feixianguan formations have been discovered in both the Luojiazhai-Puguang and Longgang areas of the Sichuan Basin, but the accumulation scale, abundance and distribution patterns differ greatly. In fact, the two areas have more differences than they have similarities. Similarities include: (1) the lithology, properties and types of porosity of the reef and oolitic reservoirs are primarily consistent in the two areas; (2) well-developed regional caprocks that seal the fluid system; and (3) accumulation process histories, with liquid hydrocarbon charging at an early stage, cracking into gas at a high to over-mature stage, adjustment of gas reservoirs at an uplifting stage, and final reservoir generation at a late stage. Differences include: (1) gas accumulations in the Luojiazhai-Puguang area that are dominated by oil-type cracked gas, with multiple and sufficient gas sources, contrasting with gas accumulations in the Longgang area that are dominated by coal-sourced gas with insufficient gas sources; (2) heterogeneity and horizontal diversity of reservoirs in the Longgang area that are stronger than in the Luojiazhai-Puguang area; and (3) the development of deep and large faults in the Luojiazhai-Puguang area that link source, reservoir and migration pathways, contrasting with poorly developed faults in Longgang area, where laterally variable fractures are the major migration pathway. Because of these differences, abundant large-scale structurally-controlled gas accumulations are developed in the Luojiazhai-Puguang area, whereas lithology plays a more important role in gas accumulation in the Longgang area where accumulations are smaller-scale and have lower gas-bearing abundance. We suggest that future exploration for reef and oolitic gas accumulations should be strengthened in NE Sichuan and NW Sichuan Jiulongshan. In particular, the transitional zone between Longgang and Kaijiang-Liangping Bay has the best potential for new discoveries. | ZHAO WenZhi XU ChunChun WANG TongShan WANG HongJun WANG ZeCheng BIAN CongSheng LI Xia | 2011 | Chinese Science Bulletin2011，56，31： | 21 |
| 3 | Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer显示文摘 | Xin Tian Baofa Sun Chuanyuan Chen Chunchun Gao Ji Zhang XingYu Lu Linchen Wang Xiangnan Li Yurong Xing Ruijuan Liu Xiao Han Zheng Qi Xiaojian Zhang Chuan He Dali Han Yun-Gui Yang Quancheng Kan | 2018 | Cell Research2018，28，5： | 12 |
| 4 | 5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer显示文摘Non-small-cell lung cancer(NSCLC), the most common type of lung cancer accounting for 85% of the cases, is often diagnosed at advanced stages owing to the lack of efficient early diagnostic tools. 5-Hydroxymethylcytosine(5 hmC) signatures in circulating cell-free DNA(cfDNA) that carries the cancer-specific epigenetic patterns may represent the valuable biomarkers for discriminating tumor and healthy individuals, and thus could be potentially useful for NSCLC diagnosis. Here,we employed a sensitive and reliable method to map genome-wide 5 hmC in the cfDNA of Chinese NSCLC patients and detected a significant 5 hmC gain in both the gene bodies and promoter regions in the blood samples from tumor patients compared with healthy controls. Specifically, we identified six potential biomarkers from 66 patients and 67 healthy controls(mean decrease accuracy>3.2, P < 3.68E-19) using machine-learning-based tumor classifiers with high accuracy. Thus,the unique signature of 5 hmC in tumor patient's cfDNA identified in our study may provide valuable information in facilitating the development of new diagnostic and therapeutic modalities for NSCLC. | Ji Zhang Xiao Han Chunchun Gao Yurong Xing Zheng Qi Ruijuan Liu Yueqin Wang Xiaojian Zhang Yun-Gui Yang Xiangnan Li Baofa Sun Xin Tian | 2018 | Genomics, Proteomics & Bioinformatics2018，16，3： | 7 |
| 5 | Effects of Rice-Fish Co-culture on Oxygen Consumption in Intensive Aquaculture Pond显示文摘Rice-fish co-culture has gained increasing attention to remediate the negative environmental impacts induced by intensive aquaculture. However, the effect of rice-fish co-culture on oxygen depletion has rarely been investigated. We constructed a rice-fish co-culture system in yellow catfish(Pelteobagrus fulvidraco) and freshwater shrimp(Macrobrachium nipponense) ponds using a new high-stalk rice variety, and conducted a field experiment to investigate the effect of rice-fish co-culture on water parameters and oxygen consumption. The results showed that rice-fish co-culture reduced the nutrients(total nitrogen, ammonia-N, total phosphorous and potassium) and the dissolved oxygen content in fish and shrimp ponds. However, they showed similar seasonal change of dissolved oxygen in the water of fish and shrimp ponds. Rice-fish co-culture reduced the total amount of oxygen consumption and optimized the oxygen consumption structure in pond. The respiration rates in water and sediment were significantly reduced by 66.1% and 31.7% in the catfish pond, and 64.4% and 38.7% in the shrimp pond, respectively, by additional rice cultivation. Rice-fish co-culture decreased the proportions of respiration in sediment and water, and increased the proportion of fish respiration. These results suggest that rice-fish co-culture is an efficient way to reduce hypoxia in intensive culture pond. | LI Fengbo SUN Zhiping QI Hangying ZHOU Xiyue XU Chunchun WU Dianxin FANG Fuping FENG Jinfei ZHANG Ning | 2019 | Rice science2019，26，1： | 4 |
| 6 | Impact of Rice-Catfish/Shrimp Co-culture on Nutrients Fluxes Across Sediment-Water Interface in Intensive Aquaculture Ponds显示文摘Exchange of nitrogen and phosphorus across sediment-water interface plays an important role in the management of nutrient recycling in the aquaculture pond. In this study, a plot experiment was conducted to study the effect of rice-catfish/shrimp co-culture on the micro-profile of oxygen (O2), pH and nutrient exchange across sediment-water interface in the intensive culture ponds. The results showed that rice-catfish co-culture increased the concentration and penetrating depth of O2, but decreased the pH value across the sediment-water interface, compared with catfish monoculture. Additional rice cultivation significantly reduced the flux rates of ammonium (NH4+) and nitrate (NO3-) across sediment-water interface in the catfish and shrimp ponds. The flux rates of NO2 - and soluble phosphorus (PO43-) showed no significant difference between rice-catfish/shrimp co-culture ponds and catfish/shrimp monoculture ponds. Rice only affected the dissolved inorganic nitrogen and phosphorus fractions in the sediment. The concentrations of NH4 + were significantly lower in the sediment of co-culture ponds than in the monoculture ponds. Additional rice cultivation also significantly reduced the content and percentage of dissolved inorganic phosphorus in the sediment of catfish ponds. | LIU Yaobin QIN Lin LI Fengbo ZHOU Xiyue XU Chunchun JI Long CHEN Zhongdu FENG Jinfei FANG Fuping | 2019 | Rice science2019，26，6： | 4 |
| 7 | A low-firing melilite ceramic Ba2CuGe207 and compositional modulation on microwave dielectric properties through Mg substitution显示文摘A melilite Ba2CuGe2O7 ceramic was characterized by low sintering temperature and moderate microwave dielectric properties.Sintered at 960℃,the Ba2CuGe2O7 ceramic had a high relative density 97%,a low relative permittivity(εr)9.43,a quality factor(Q×f)of 20,000 GHz,and a temperature coefficient of resonance frequency(τf)-76 ppm/℃.To get a deep understanding of the relationship between composition,structure,and dielectric performances,magnesium substitution for copper in Ba2CuGe2O7 was conducted.Influences of magnesium doping on the sintering behavior,crystal structure,and microwave dielectric properties were studied.Mg doping in Ba2CuGe2O7 caused negligible changes in the macroscopic crystal structure,grain morphology,and size distribution,while induced visible variation in the local structure as revealed by Raman analysis.Microwave dielectric properties exhibit a remarkable dependence on composition.On increasing the magnesium content,the relative permittivity featured a continuous decrease,while both the quality factor and the temperature coefficient of resonance frequency increased monotonously.Such variations in dielectric performances were clarified in terms of the polarizability,packing fraction,and band valence theory. | Changzhi YIN Zezong YU Longlong SHU Laijun LIU Yan CHEN Chunchun LI | 2021 | Journal of Advanced Ceramics2021，10，1： | 3 |
| 8 | The outbreak of rabbit hemorrhagic virus type 2 in the interior of China may be related to imported semen显示文摘Dear Editor,Rabbit hemorrhagic disease(RHD)is a fatal infectious disease that primarily affects adult rabbits and causes great economic losses in the rabbit industry(Mitro and Krauss,1993).The causative pathogen is rabbit hemorrhagic disease virus(RHDV),which belongs to the genus Lagovirus and the family Calicivirus(Moussa et al.,1992).In 1984,RHDV was first documented in China. | Ruibin Qi Chunchun Meng Jie Zhu Hang Li Qiuhong Miao Jingyu Tang Aoxing Tang Hongyuan Guo Chuncao Liu Chuanfeng Li Zongyan Chen Fang Wang Qinwen Zhang Guangqing Liu | 2022 | Virologica Sinica2022，37，4： | 3 |
| 9 | AEROELASTIC PROPERTIES OF SANDWICH BEAM WITH PYRAMIDAL LATTICE CORE CONSIDERING GEOMETRIC NONLINEARITY IN THE SUPERSONIC AIRFLOW显示文摘The equation of motion of sandwich beam with pyramidal lattice core in the supersonic flow considering geometric nonlinearity is formulated using Hamilton's principle. The piston theory is used to evaluate aerodynamic pressure. The structural aeroelastic properties are analyzed using frequency- and time-domain methods, and some interesting phenomena are observed. It is noted that the flutter of sandwich beam occurs under the coupling effect of low order modes. The critical flutter aerodynamic pressure of the sandwich beam is higher than that of the isotropic beam with the same weight, length and width. The influence of inclination angle of core truss on flutter characteristic is analyzed. | Fengming Li Zhiguang Song Chunchun Sun | 2015 | Acta Mechanica Solida Sinica2015，28，6： | 3 |
| 10 | Rationally designed Ta_(3)N_(5)/BiOCl S-scheme heterojunction with oxygen vacancies for elimination of tetracycline antibiotic and Cr(Ⅵ):Performance,toxicity evaluation and mechanism insight显示文摘S-scheme heterojunction photocatalysts have been the“stars”in the field of photocatalysis.Herein,a novel S-scheme heterojunction of Ta_(3)N_(5)/BiOCl with oxygen vacancies(OVs)was fabricated via a facile method.The charge separation and transport mechanism of this Ta_(3)N_(5)/BiOCl S-scheme heterojunction was verified by the analyses of band energy structures,active species,photoelectric behaviors and DFT theoretical calculation.Compared with Ta_(3)N_(5)and BiOCl,the Ta_(3)N_(5)/BiOCl unveils substantially upgraded photocatalytic property under visible light,and the photocatalytic efficiency for removal of tetracycline(TC)and hexavalent chromium(Cr(VI))reaches 89.6%and 91.6%,respectively.The substantial enhancement of the photocatalytic activity is attributed to the synergistic effect of the S-scheme hetero-structure and oxygen vacancies,which improves the visible-light absorption,while promoting the spatial separation of charge carriers with the optimum redox capacity,thereby boosting the production of active species for catalytic reactions.The TC degradation pathway is deduced and the toxicity evolution of TC is appraised using the QSAR method.In a nutshell,this work gives a deep understanding of the photocatalytic mechanism based on Ta_(3)N_(5)/BiOCl as well as presents a newfangled thought for developing highly efficient S-scheme heterojunction photocatalysts for water decontamination. | Shijie Li Mingjie Cai Chunchun Wang Yanping Liu Neng Li Peng Zhang Xin Li | 2022 | Journal of Materials Science & Technology2022，，28： | 2 |
| 11 | Complex impedance analysis on a layered perovskite-like ceramic:La3Ti2TaO11显示文摘 | LI Chunchun WEI Xiaoyong | 2012 | J Mater Sci2012，47，42： | 1 |
| 12 | Microwave dielectric properties of temperature stable Li 2 Zn x Co 1? x Ti 3 O 8 ceramics显示文摘 | Liang Fang Dongjin Chu Huanfu Zhou Xiuli Chen Hui zhang Baocheng Chang Chunchun Li Yuandong Qin Xi Huang | 2011 | Journal of Alloys and Compounds2011，，： | 1 |
| 13 | Liquid metal-based plant electronic tattoos for in-situ monitoring of plant physiology显示文摘Flexible plant sensors,as a noninvasive and real-time monitoring method for plant physiology,are becoming crucial for precision agriculture.However,integrating flexible devices with plants are challenging due to their fragility and complex surfaces.In this study,we introduce a liquid metal-based plant electronic tattoo(LM-PET)that can harmlessly and continuously monitor the loss of water content and plant electrical signals,which are critical parameters for analyzing plant physiological status.The LM-PET achieves double-sided conductivity through soluble electrostatic spinning films and transferring technology,effectively addressing the issue of mismatch between the rigid interface of electronic devices and the surface of delicate plants.The fabricated tattoo electrode can adhere tightly to the leaf surface for a long time and can significantly broaden the scope of moisture monitoring,even in cases of severe wrinkling caused by water loss.At the optimum operating frequency of 100 kHz,the sensitivity of LM-PET can reach 25.4 kΩ%^(-1).Thus,LM-PETs can record the electrical signals generated when abiotic stresses threaten plants.They are also significant in providing a deeper understanding of the drought adaptation mechanisms of plants and developing drought-resistant varieties.They offer data-driven crop management and decision-making guidance,which is imperative for advancing precision agriculture.Overall,our findings provide valuable insights into the performance of agricultural inputs and facilitate real-time monitoring of plant growth and development. | QU ChunChun CAO LingXiao LI MaoLin WANG XiQing HE ZhiZhu | 2023 | Science China(Technological Sciences)2023，66，6： | 1 |
| 14 | Effect of Cadmiuum on Autoxidation Rate of Tissue and Inducing Accumulation of Free Proline in Seedlings of Mung Bean显示文摘 | Fenqin Zhang Xiangdong Li Chunchun Wang | | JOURNAL OF PLANT NUTRITION0，23，3： | 1 |
| 15 | High yield expression of duck hepatitis A virus VP1 protein in Escherichia coli,and production and characterization of polyclonal antibody显示文摘 | CHUANFENG LI ZONGYAN CHEN CHUNCHUN MENG | 2013 | Journal of Virological Methods2013，191，： | 1 |
| 16 | Ta_(3)N_(5)/CdS Core–Shell S‑scheme Heterojunction Nanofibers for Efficient Photocatalytic Removal of Antibiotic Tetracycline and Cr(VI):Performance and Mechanism Insights显示文摘Ta_(3)N_(5)/CdS core–shell S-scheme heterojunction nanofibers are fabricated by in situ growing CdS nanodots on Ta_(3)N_(5) nanofib-ers via a simple wet-chemical method.These Ta_(3)N_(5)/CdS nanofibers not only affords superior photocatalytic tetracycline degradation and mineralization performance,but also cause an efficient photocatalytic Cr(VI)reduction performance.The creation of favorable core–shell fiber-shaped S-scheme hetero-structure with tightly contacted interface and the maximum interface contact area promises the effective photo-carrier disintegration and the optimal photo-redox capacity synchronously,thus leading to the preeminent photo-redox ability.Some critical environmental factors on the photo-behavior of Ta_(3)N_(5)/CdS are also evaluated in view of the complexity of the authentic aquatic environment.The degradation products of tetracycline were confirmed by HPLC–MS analyses.Furthermore,the effective decline in eco-toxicity of TC intermediates is confirmed by QSAR calculation.This work provides cutting-edge guidelines for the design of high-performance Ta_(3)N_(5)-based S-scheme heterojunction nanofibers for environment restoration. | Shijie Li Mingjie Cai Chunchun Wang Yanping Liu | 2023 | Advanced Fiber Materials2023，5，3： | 1 |
| 17 | Compositional modulation in ZnGa_(2)0_(4) via Zn^(2+)/Ge^(4+)co-doping to simultaneously lower sintering temperature and improve microwave dielectric properties显示文摘AB_(2)O_(4)-type spinels with low relative permittivity(ε_(τ))and high quality factor(Q×f)are crucial to high-speed signal propagation systems.In this work,Zn^(2+)/Ge^(4+) co-doping to substitute Ga in ZnGa_(2)O_(4) was designed to lower the sintering temperature and adjust the thermal stability of resonance frequency simultaneously.Zn_(1+2)Ga_(2-2x)Ge_(x)O_(4)(0.1≤x≤0.5)ceramics were synthesised by the conventional solid state method.Zn^(2+)/Ge^(4+) co-substitution induced minimal variation in the macroscopical spinel structure,which effectively lowered the sintering temperature from 1385 to 1250℃.All compositions crystallized in a normal spinel structure and exhibited dense microstructures and excellent microwave dielectric properties.The compositional dependent quality factor was related to the microstructural variation,being confirmed by Raman features.A composition with x=0.3 shows the best dielectric properties with ε_(τ) ≈10.09,Q×f≈112,700 THz,and ε_(τ) ≈-75.6 ppm/℃.The negative τf value was further adjusted to be near-zero through the formation of composite ceramics with TiO_(2). | Ying XIONG Hongyuan XIE Zhenggang RAO Laijun LIU Zhengfeng WANG Chunchun LI | 2021 | Journal of Advanced Ceramics2021，10，6： | 0 |
| 18 | Entropy regulation in LaNbO_(4)-based fergusonite to implement high-temperature phase transition and promising dielectric properties显示文摘High-entropy effect is a novel design strategy to optimize properties and explore novel materials.In this work,(La_(1/5)Nd_(1/5)Sm_(1/5)Ho_(1/5)Y_(1/5))NbO_(4)(5RNO)high-entropy microwave dielectric ceramics were successfully prepared in the sintering temperature(S.T.)range of 1210–1290℃via a solid-phase reaction route,and medium-entropy(La_(1/3)Nd_(1/3)Sm_(1/3))NbO_(4) and(La_(1/4)Nd_(1/4)Sm_(1/4)Ho_(1/4))NbO_(4)(3RNO and 4RNO)ceramics were compared.The effects of the entropy(S)on crystal structure,phase transition,and dielectric performance were evaluated.The entropy increase yields a significant increase in a phase transition temperature(from monoclinic fergusonite to tetragonal scheelite structure).Optimal microwave dielectric properties were achieved in the high-entropy ceramics(5RNO)at the sintering temperature of 1270℃for 4 h with a relative density of 98.2%and microwave dielectric properties of dielectric permittirity(ε_(r))=19.48,quality factor(Q×f)=47,770 GHz,and resonant frequency temperature coefficient(τ_(f))=–13.50 ppm/℃.This work opens an avenue for the exploration of novel microwave dielectric material and property optimization via entropy engineering. | Deqin Chen Na Yan Xuefeng Cao Fengrong Li Laijun Liu Qinghua Shen Huanfu Zhou Chunchun Li | 2023 | Journal of Advanced Ceramics2023，12，5： | 0 |
| 19 | Forkhead box protein O1(FoxO1)regulates lipids metabolism and cell proliferation mediated by insulin and PI3K-Akt-mTOR pathway in goose primary hepatocytes显示文摘In order to explore the role of forkhead box protein O1(FoxO1)in the lipid metabolism and cell proliferation,goose primary hepatocytes were isolated and incubated with insulin or PI3K-Akt-mTOR pathway dual inhibitor NVPBEZ235,and then transfected with FoxO1 interference plasmid.The related parameters of lipid metabolism and cell proliferation were measured.The results firstly showed that FoxO1 interference increased the intracellular TG and lipids concentration(P<0.05);and increased the proliferative index(PI),cell DNA synthesis,protein expression of Cyclin D1 in goose primary hepatocytes(P<0.05).Secondly,the co-treatment of insulin and FoxO1 interference increased the mRNA level and protein content of Cyclin D1(P<0.05);however,there was no significant difference between the insulin treatment and the co-treatment of insulin and miR-FoxO1 interference in the intracellular TG and lipids concentration and PI(P>0.05).Lastly,the decrease of intracellular TG and lipids concentration and PI induced by NVP-BEZ235 was up-regulated by FoxO1 interference significantly(P<0.05).In summary,FoxO1 could regulate the lipids metabolism and cell proliferation mediated by PI3K-Akt-mTOR signaling pathway in goose primary hepatocytes.Further investigations are required to highlight the potential role of FoxO1 in the lipid metabolism and cell proliferation mediated by insulin in goose primary hepatocyte. | RONGXUE WEI CHUNCHUN HAN FENGJIANG YE SHOUHAI WEI FANG HE HEHE LIU LIANG LI HONGYONG XU SHENQIANG HU XIANYIN ZENG | 2022 | BIOCELL2022，46，1： | 0 |
| 20 | Current and future control of the wood-boring pest Anoplophora glabripennis显示文摘The Asian longhorn beetle (ALB) Anoplophora glabripennis is one of the most successful and most feared invasive insect species worldwide. This review covers recent research concerning the distribution of and damage caused by ALB, as well as major efforts to control and manage ALB in China. The distribution and destruction range of ALB have continued to expand over the past decade worldwide, and the number of interceptions has remained high. Detection and monitoring methods for the early discovery of ALB have diversified, with advances in semiochemical research and using satellite remote sensing in China. Ecological control of ALB in China involves planting mixtures of preferred and resistant tree species, and this practice can prevent outbreaks. In addition, strategies for chemical and biological control of ALB have achieved promising results during the last decade in China, especially the development of insecticides targeting different stages of ALB, and applying Dastarcus helophoroides and Dendrocopos major as biocontrol agents. Finally, we analyze recommendations for ALB prevention and management strategies based on native range and invasive area research. This information will hopefully help some invaded areas where the target is containment of ALB. | Lixiang Wang Chunchun Li Youqing Luo Gaijing Wang Zhipeng Dou Inzamam UI Haq Suqing Shang Mingming Cui | 2023 | Insect Science2023，30，6： | 0 |
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