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| 1 | Variations in zonal fruit starch concentrations of apples – a developmental phenomenon or an indication of ripening?显示文摘Patterns of starch hydrolysis in stem,equatorial,and calyx zones of‘Honeycrisp’and‘Empire’apples(Malus sylvestris(L.)Mill var.domestica(Borkh.)Mansf.)during maturation and ripening,and in‘Gala’apples in response to propylene or 1-methylcyclopropene(1-MCP)treatments after harvest,were studied.Differences in zonal starch concentrations were found for‘Empire’and‘Gala’fruits,but not for‘Honeycrisp’.During maturation and ripening of‘Empire’,the concentration of starch was highest in the calyx end and lowest in the stem region.Differences in rates of starch hydrolysis among zones were not detected.‘Honeycrisp’and‘Empire’had the highest concentration of sorbitol in the calyx region,whereas it was highest in the stem-end region in‘Gala’.The distribution differences of glucose,fructose,and sucrose were similar in all three cultivars;higher fructose and glucose concentrations in the stem region,and higher sucrose concentrations in the calyx end of the fruit.Postharvest treatment of‘Gala’with propylene did not affect the internal ethylene concentration of the fruit but 1-MCP markedly inhibited it.Starch concentrations were highest in the calyx end but gradients of starch among zones were not changed by postharvest treatment.The rate of hydrolysis was slowed by 1-MCP treatment,but was unaffected by propylene.Postharvest treatments influenced sorbitol,glucose,and fructose concentrations.Patterns of starch concentration among the zones did not confirm differences in ripening,but reflected its uneven distribution throughout the fruit during development.Therefore,measured differences in zonal starch are most likely related to starch accumulation during fruit development,rather than differences in rates of starch degradation during ripening. | Franziska C Doerflinger William B Miller Jacqueline F Nock Christopher B Watkins | 2015 | Horticulture Research2015，2，1： | 3 |
| 2 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 3 | A multibit E A modulator in floating-body SOS/SOI CMOS for extreme radiation environments显示文摘 | CHRISTOPHER F E WILLIAM R W MARK B | 1999 | IEEE J of Solid State Circuits1999，34，7： | 1 |
| 4 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 5 | Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus 显示文摘 | CHRISTOPHER G B SARAH F CECILIA M L | 2010 | PLoS One2010，5，14： | 1 |
| 6 | Development of chromium nltride coatings substituting titanium nltrlde 显示文摘 | Günter B Christoph F Erhard B | 1996 | Surface and Coatings Technology1996，8687，1： | 1 |
| 7 | Most mammalian mRNAs are conserved targets of microRNAs显示文摘 | Robin C F Kyle K F Christopher B B | 2009 | Genome Research2009，19，： | 1 |
| 8 | Synthesis and antifungal activity of a ferrocene-flu- conazole analogue 显示文摘 | CHRISTOPHE B NADINE F LUCIEN M | 2000 | Bioorg Med Chem Lett2000，10，： | 1 |
| 9 | Anti-apoptotic effect of benidipine, a long-lasting vasodilating calcium antagonist, in ischaemic/reperfused myocardial cells显示文摘 | Gao F Gong B Christopher TA | 2001 | Br J Pharmacol2001，132，4： | 1 |
| 10 | Preparation and Properties of CrN Coatings显示文摘 | Christoph F Erhard B | 1996 | Surface and Coatings Technology1996，，2： | 1 |
| 11 | Synthesis of Highly Ordered,Three-Dimensional,Macroporous Structures of Amorphous or Crystalline Inorganic Oxides,Phosphates,and Hybrid Composites显示文摘 | Brian T H Christopher F B Thang D | 2004 | Chem Mater2004，16，11： | 1 |
| 12 | A hierarchical factor analysis of a safety culture survey显示文摘 | Christopher B F Timothy D L Brian W | 2013 | Journal ofSafety Research2013，45，2： | 1 |
| 13 | Enhancement of Latent Heat Energy Storage Using Embedded Heat Pipes 显示文摘 | Christopher W R Theodore L B Amir F | 2011 | International Journal of Heat and Mass Transfer2011，，54： | 1 |
| 14 | Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia显示文摘 | Jeremy W Fox Edward D Lamperti Yaman Z Ek?io?lu Susan E Hong Yuanyi Feng Donna A Graham Ingrid E Scheffer William B Dobyns Betsy A Hirsch Rodney A Radtke Samuel F Berkovic Peter R Huttenlocher Christopher A Walsh | 1998 | Neuron1998，，6： | 1 |
| 15 | Experimental generation of parabolic pulses via raman amplification in optical fiber显示文摘 | CHRISTOPHE F GUY M CYRIL B | 2003 | Opt Exp2003，11，13： | 1 |
| 16 | The N- and C-terminal regions of the pearl associated EF hand protein, PFMG1, promote the formation of the aragonite polymorph in vitro 显示文摘 | Fairland F A Edly Destine Christopher B P | 2010 | Crystal Growth and Design2010，10，10： | 1 |
| 17 | General synthesis of periodic macroporous solids by templated salt precipitation and chemical conversion显示文摘 | HONGWEI Y CHRISTOPHER F B BRIAN T H | 2000 | Chem Mater2000，12，： | 1 |
| 18 | Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis显示文摘 | CHRISTOPHER B F ASHKAN F SHRIRAM M J | 2009 | Alcohol2009，43，： | 1 |
| 19 | The morphology of built-up landscapes in Wallonia (Belgium):A classification using fractal indices显示文摘 | Isabelle T Pierre F Christophe B | 2008 | Landscape and Urban Planning2008，84，2： | 1 |
| 20 | Geometric constraint solver 显示文摘 | WILLIAM B LOANNIS F CHRISTOPH H | 1995 | Computer-Aided Design1995，27，6： | 1 |
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