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| 1 | Non-invasive fibrosis assessment in non-alcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is estimated to affect approximately 25%of the adult population worldwide.[1]NAFLD encompasses a histopathological spectrum of progressive pathologic conditions ranging from non-alcoholic fatty liver(NAFL)to steatohepatitis(NASH)and cirrhosis. | Rafael S.Rios Kenneth I Zheng Giovanni Targher Christopher D.Byrne Ming-Hua Zheng | 2020 | Chinese Medical Journal2020，，22： | 4 |
| 2 | Optimization and kinetic studies for enzymatic hydrolysis and fermentation of colocynthis vulgaris Shrad seeds shell for bioethanol production显示文摘The key process parameters for the hydrolysis and fermentation of Colocynthis vulgaris Shrad seeds shell(CVSSS)were optimized using the Box-Behnken Design(BBD)of Response Surface Methodology(RSM).Kinetic study was also carried out.The proximate analysis of the CVSSS was done by the method of the Association of Organic and Applied Chemistry(AOAC).Enzymatic hydrolysis was experimented by using Aspergillus Niger as a crude enzyme isolated from soil at sawdust dump site and screened for cellulosic activities.Factors that affected the hydrolysis of the CVSSS were screened by using the Greco-Latin square design of experiment.However,for Saccharomyces cerevisiae,factors that affected the fermentation of the CVSSS were screened by using the same Greco-Latin square design of experiment.Meanwhile,the result of the proximate analysis revealed that the CVSSS had 73.54%cellulose which could be converted to bioethanol.It was established that temperature,pH and time had significant effect on hydrolysis,while the optimum results were obtained at 46.8℃,3.32 d,5.68 and 59.87%for temperature,time,pH and glucose yield,respectively.Temperature,yeast dosage,pH and time had significant effect on fermentation,while the optimum results from optimization were found to be 33.58℃,7.0,3.55 d,1.65 g per 50 mL and 25.6%for temperature,pH,time,yeast dosage and ethanol yield,respectively.The kinetics of both the enzymatic hydrolysis and fermentation agreed with the Michealis-Menten kinetic model with the correlation coefficients(R^(2))of 0.9708 and 0.8773,respectively.However,from the error analysis,the experimental and predicted values had a very good relationship as described by Michaelis-Menten model. | Igwilo Christopher Nnaemeka Egbuna Samuel O Onoh Maxwell I Asadu OChristain Onyekwulu Chinelo S | 2021 | Journal of Bioresources and Bioproducts2021，6，1： | 3 |
| 3 | The role of advanced paternal age in modern reproductive medicine显示文摘 | Christopher Wu Larry I Lipshultz Jason R Kovac | 2016 | Asian Journal of Andrology2016，18，3： | 3 |
| 4 | Identification of telmisartan as a unique angiotensin Ⅱ receptor antagonist with selective ppargamma- modulating activity 显示文摘 | Stephen C Benson Harrihar A Pershadsingh Christopher I Ho | 2004 | Hypertension2004，43，： | 1 |
| 5 | Measures of Diversity in Classifier Ensembles显示文摘 | Ludmila I K Christopher J W | 2003 | Machine Learning2003，51，1： | 1 |
| 6 | Zoellick, Distribution of dopamine in the brain显示文摘 | Christopher R Malone Gian Pauletto James I | 1991 | The Journal of Under graduate Mathematics and its Applications Special Issue: The 1991 Math- ematical Contest in Modeling1991，1991，12： | 1 |
| 7 | Design of robust control systems for a hypersonic aircraft显示文摘 | Christopher I Maxrison and Robert F Stengel | 1998 | Journal of Guidance Control and Dynamics1998，21，1： | 1 |
| 8 | Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARY modulating activity 显示文摘 | Stephen C Harrihar A Christopher I | 2004 | Hypertention2004，43，： | 1 |
| 9 | Communication and the Primate Brain: Insights from Neuroimaging Studies in Humans, Chimpanzees and Macaques显示文摘 | Wilson Benjamin Petkov Christopher I | 2011 | Human Biology2011，，2： | 1 |
| 10 | Tri- fluoroethylamines as amide isosteres in inhibitors of cathepsin K 显示文摘 | dCameron Black W Christopher I Bayly Dana E Davis | 2005 | Bioorganic & Medicinal Chemistry Letters2005，15，21： | 1 |
| 11 | Mycophenolic acid antagonizes the activation of cultured human mesangial cells 显示文摘 | Dubus I Vendrely B Christophe I | 2002 | Kidneylnt2002，62，： | 1 |
| 12 | Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial显示文摘 | Marcia S Brose Christopher M Nutting Barbara Jarzab Rossella Elisei Salvatore Siena Lars Bastholt Christelle de la Fouchardiere Furio Pacini Ralf Paschke Young Kee Shong Steven I Sherman Johannes W A Smit John Chung Christian Kappeler Carol Pe?a István Mo | 2014 | The Lancet2014，，： | 1 |
| 13 | Optical parametric chirped-pulse amplifier as an alternative to Ti: sapphire regenerative amplifiers显示文摘 | Jovanovic I Comaskey B J Christopher A E | 2002 | Applied Optics2002，41，15： | 1 |
| 14 | A Riccati equation approach to the stabilization of uncertain linear systems显示文摘 | Petersen I R Hollot Christopher V | 1986 | Automatica1986，22，4： | 1 |
| 15 | Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARY modulating activity显示文摘 | Stephen C Harrihar A Christopher I | 2004 | Hypertention2004，43，6： | 1 |
| 16 | Program optimization carving for GPU computing显示文摘 | SHANE R CHRISTOPHER R I Sams S | 2008 | Journal of Parallel and Distributed Computing2008，68，10： | 1 |
| 17 | Gastrointestinal:spiral CT pneumocolon: applications, status and limitations显示文摘 | Christopher J Renfrew I | 2001 | European Radiology2001，11，： | 1 |
| 18 | J Phys Chem B显示文摘 | Ranasinghe Mahinda I Hager Michael W Gorman Christopher B | 2004 | 108(25):8543-85492004，108，25： | 1 |
| 19 | A Riccati equation approach to the stabilization of uncertain linear systems 显示文摘 | Petersen I R Hollot Christopher V | 1986 | Automatica1986，22，4： | 1 |
| 20 | Gdt2 regulates the transition of Dictyostelium cells from growth to differentiation显示文摘 | Margarita V C Christophe A Robert H I | 2004 | BMC Dev Biol2004，4，1： | 1 |
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