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4篇 您的检索式：作者名="Chrishan Samuel"

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		题名	作者	年代	出处	被引量
	1	SAHA attenuates Takotsubo-like myocardial injury by targeting an epigenetic Ac/Dc axis显示文摘Dear Editor,Takotsubo syndrome(TS)is a stress-induced non-ischaemic cardiomyopathy that is more common in women,but is associated with higher morbidity and mortality in males.Also known as broken-heart syndrome,TS is characterised by transient left ventricular(LV)dysfunction independent of obstructive coronary artery disease.TS is a polygenic condition and nowhere is this more evident than the use of positive inotropes,such as isoprenaline(ISO)in pre-clinical models.1 There is no standard therapy for broken-heart syndrome because the mechanisms underlying the condition remain unknown.Furthermore,there is no consensus on predisposition for Takotsubo2 and our goal was to better understand the regulatory mechanism as a first step towards improved treatment plans.Suberanilohydroxamic acid or SAHA,a drug approved for cancer treatment by the US Food and Drug Administration has previously been shown to improve cardiopulmonary function.3 We tested the hypothesis that the cardioprotective benefit of SAHA in a pre-clinical model of Takotsubo is conferred by an epigenetic acetylation/deacetylation(Ac/Dc)axis.	Ishant Khurana Scott Maxwell Simon Royce Prabhu Mathiyalagan Tom Karagiannis Nadia Mazarakis Jitraporn Vongsvivut Harikrishnan K.N. Jun Okabe Keith Al-Hasani Chrishan Samuel Assam El-Osta	2021	Signal Transduction and Targeted Therapy2021，6，5：	1
	2	Relaxin Regulates Myofibroblast Contractility and Protects against Lung Fibrosis显示文摘	Xiangwei Huang Ying Gai Naiheng Yang Baogen Lu Chrishan S. Samuel Victor J. Thannickal Yong Zhou	2011	The American Journal of Pathology2011，，6：	1
	3	Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury显示文摘	Yuben Moodley Daniel Atienza Ursula Manuelpillai Chrishan S. Samuel Jorge Tchongue Sivakami Ilancheran Richard Boyd Alan Trounson	2009	The American Journal of Pathology2009，，1：	1
	4	Electrophysiological, Electroanatomical, and Structural Remodeling of the Atria as Consequences of Sustained Obesity显示文摘	Rajiv Mahajan Dennis H. Lau Anthony G. Brooks Nicholas J. Shipp Jim Manavis John P.M. Wood John W. Finnie Chrishan S. Samuel Simon G. Royce Darragh J. Twomey Shivshanker Thanigaimani Jonathan M. Kalman Prashanthan Sanders	2015	Journal of the American College of Cardiology2015，，：	1

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