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| 1 | Clinical importance of aspirin and clopidogrel resistance显示文摘Aspirin and clopidogrel are important components of medical therapy for patients with acute coronary syndromes, for those who received coronary artery stents and in the secondary prevention of ischaemic stroke. Despite their use, a significant number of patients experience recurrent adverse ischaemic events. Interindividual variability of platelet aggregation in response to these antiplatelet agents may be an explanation for some of these recurrent events, and small trials have linked 'aspirin and/or clopidogrel resistance', as measured by platelet function tests, to adverse events. We systematically reviewed all available evidence on the prevalence of aspirin/clopidogrel resistance, their possible risk factors and their association with clinical outcomes. We also identified articles showing possible treatments. After analyzing the data on different laboratory methods, we found that aspirin/clopidogrel resistance seems to be associated with poor clinical outcomes and there is currently no standardized or widely accepted definition of clopidogrel resistance. Therefore, we conclude that specific treatment recommendations are not established for patients who exhibit high platelet reactivity during aspirin/clopidogrel therapy or who have poor platelet inhibition by clopidogrel. | Gergely Feher Andrea Feher Gabriella Pusch Katalin Koltai Antal Tibold Beata Gasztonyi Elod Papp Laszlo Szapary Gabor Kesmarky Kalman Toth | 2010 | World Journal of Cardiology2010，2，7： | 36 |
| 2 | A study of solid ramjet fuel containing boron–magnesium mixtures显示文摘Solid fuel ramjets (SFRJ) are known for their operational simplicity and high specific impulse. The performance of the SFRJ propulsion system is directly tied to the energy density and combustion behavior of the fuel. A typical solid fuel used in a ramjet application is a collection of metal particles suspended in a polymeric binder. Boron is the ubiquitous candidate when considering metal additives for fuels due to an impressive 122.5 kJ/cm3 energy density. However, boron requires long residence times in combustors due to its high melting and boiling points. Magnesium appears to be a natural complement to boron;while possessing a lower energy density (42.1 kJ/cm3), it burns with a high flame temperature and readily reacts in combustion with a low melting point. In this study, several HTPB–boron–magnesium fuels are studied on a small scale to evaluate performance for ramjet application. Holography experiments are conducted, as well as laser ignition tests, to study particle behavior just above the fuel surface. Small, center-perforated fuel grains are examined in a direct-connect SFRJ test stand configuration to measure ignition temperatures and performance parameters. Combustion efficiency of the HTPB–boron–magnesium fuel is found to significantly increase for one of the fuels studied. | Eric T.Sandall Joseph Kalman John N.Quigley Scott Munro Trevor D.Hedman | 2017 | Propulsion and Power Research2017，6，4： | 4 |
| 3 | Pulmonary embolization as primary manifestation of hepatocellular carcinoma with intracardiac penetration: A case report显示文摘Intracardiac manifestation of hepatocellular carcinoma (HCC) is a rare condition and an uncommon finding even at autopsy. Pulmonary tumor embolism as a presenting feature of HCC has been published only twice previously.In our case report, a 63-year-old man presented with high fever and six episodes of recurrent pneumonias during the last half year. Echocardiography was performed, a solid mass was found in the right atrium. Transesophageal echocardiography proved a tumor mass in the inferior vena cava (ⅣC) extending into the right atrium, abdominal ultrasound revealed tumor mass in the ⅣC and a solid tumor in the liver. Combined liver and heart surgery was attempted in order to remove the tumor mass from both the liver and the right atrium. Acute cor pulmonale occurred during tumor removal from the right atrium and the patient expired. In addition to local factors the possibility of embolization should arise in the background of recurrent pneumonia. Occult carcinoma must be included in possible causes of recurrent pulmonary embolism. Searching for primary malignancy should include HCC as frequent cause of hypercoagulability. In case of HCC, echocardiography is suggested because of the possibility of expansion in MC or right atrium and tumor-embolization. | Elod Papp Zsuzsanna Keszthelyi Nagy Karoly Kalmar Lajos Papp Csaba Weninger Tamas Tornoczky Endre Kalman Kalman Toth Tamas Habon | 2005 | World Journal of Gastroenterology2005，11，15： | 4 |
| 4 | Accelerating CFD–DEM simulation of processes with wide particle size distributions显示文摘Size-reduction systems have been extensively used in industry for many years. Nevertheless, reliable engineering tools to be used to predict the comminution of particles are scarce. Computational fluid dynamics(CFD)–discrete element model(DEM) numerical simulation may be used to predict such a complex phenomenon and therefore establish a proper design and optimization model for comminution systems.They may also be used to predict attrition in systems where particle attrition is significant. Therefore,empirical comminution functions(which are applicable for any attrition/comminution process), such as:strength distribution, selection, equivalence, breakage, and fatigue, have been integrated into the threedimensional CFD–DEM simulation tool. The main drawback of such a design tool is the long computational time required owing to the large number of particles and the minute time-step required to maintain a steady solution while simulating the flow of particulate materials with very fine particles.The present study developed several methods to accelerate CFD–DEM simulations: reducing the number of operations carried out at the single-particle level, constructing a DEM grid detached from the CFD grid enabling a no binary search, generating a sub-grid within the DEM grid to enable a no binary search for fine particles, and increasing the computational time-step and eliminating the finest particles in the simulation while still tracking their contribution to the process.The total speedup of the simulation process without the elimination of the finest particles was a factor of about 17. The elimination of the finest particles gave additional speedup of a factor of at least 18.Therefore, the simulation of a grinding process can run at least 300 times faster than the conventional method in which a standard no binary search is employed and the smallest particles are tracked. | Tamir Brosh Haim Kalman Avi Levy | 2014 | Particuology2014，12，1： | 3 |
| 5 | 房颤消融中心腔内超声引导下的房间隔穿刺显示文摘目的 应用心腔内超声引导房间隔穿刺 ,评价心腔内超声引导房间隔穿刺的安全性与效果。方法 8例阵发性房颤患者 ,电生理检查证实为起源于左心房肺静脉口处的局灶性房颤 ,需要穿刺房间隔。应用经导管心腔内超声观察心脏结构 ,放置超声导管探头于卵圆窝处 ,显示卵圆窝和其周围结构 ,指导房间隔穿刺。扩张器于卵圆窝形成典型的“帐篷状”(Tenting)征象。 8例患者 ,除 2例因术者对超声图像和技术不熟练外 ,其余均一次试穿成功 ,平均时间为 (14 2± 3 5 )min ,无并发症 ,穿刺时间与卵圆窝长度、卵圆窝与左房壁距离呈负相关。结论 心腔内超声能很好显示X线透视下无法直观显示的卵圆窝及其周围结构 ,使穿刺定位更为精确 ,有效地避免并发症 ,是一项很有前途的技术。 | 吴永全 胡大一 商丽华 杨新春 郭成军 张建军 李宜富 秦绪光 吴阳 Kalman JM | 2000 | 中国介入心脏病学杂志2000，8，2： | 3 |
| 6 | Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial Fibrillation显示文摘 | Riccardo Cappato Hugh Calkins Shih-Ann Chen Wyn Davies Yoshito Iesaka Jonathan Kalman You-Ho Kim George Klein Douglas Packer Allan Skanes | 2005 | Circulation2005，，9： | 3 |
| 7 | Elevated circulating levels of tumor necrosis factor in severe chronic heart failure显示文摘 | Levine B Kalman J Mayer L | 1990 | N Engl J Med1990，323，4： | 2 |
| 8 | Updated Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial Fibrillation显示文摘 | Riccardo Cappato Hugh Calkins Shih-Ann Chen Wyn Davies Yoshito Iesaka Jonathan Kalman You-Ho Kim George Klein Andrea Natale Douglas Packer Allan Skanes Federico Ambrogi Elia Biganzoli | 2010 | Circulation: Arrhythmia and Electrophysiology2010，，1： | 2 |
| 9 | Mechanism of initiation of atrial flutter in humans:site of unidirectional block and direction of rotation显示文摘 | Olgin JE Kalman JM Saxon LA | 1997 | J Am Coll Cardiol1997，29，2： | 1 |
| 10 | Numerical analysis of the dynamic effects of shock-load-induced ice shedding on overhead ground wires显示文摘 | Kalman T Farzaneh M McClure G | 2007 | Computers & Structures2007，，85： | 1 |
| 11 | A new approach linear filtering and prediction problems 显示文摘 | Kalman R E | 1960 | Journal of Basic Engineering ( ASME)1960，82，： | 1 |
| 12 | Family correlations of arsenic methylation patterns in children and parents exposed to high concentrations of arsenic in drinking water显示文摘 | Chung JS Kalman DA Moore LE | 2002 | Environ Health Perspect2002，110，： | 1 |
| 13 | Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia显示文摘 | ROSSO R KALMAN JM ROGOWSKI O | 2007 | Heart Rhythm2007，4，9： | 1 |
| 14 | A new approach to linear filtering and prediction problems显示文摘 | Kalman R E | 1960 | Journal of Basic Engineering1960，82，1： | 1 |
| 15 | A new approach to linear filtering and prediction problems显示文摘 | Kalman R E | 1960 | Transactions of the AMSE Journal of Basic Engineering1960，82，1： | 1 |
| 16 | A new approach to linear filtering and prediction problems显示文摘 | Kalman R E | 1960 | Journal of Basic Engineer- ing1960，82，1： | 1 |
| 17 | Monitoring of respiratory rate in postoperative care using a new photoplethysmographic technique显示文摘 | Nilsson L Johansson A Kalman S | 2000 | Journal of Clinical Monitoring and Computing2000，16，4： | 1 |
| 18 | Evidence of genetic heterogeneity in the long QT syndrome显示文摘 | Kalman YM Medina A | 1993 | Science1993，260，5116： | 1 |
| 19 | Early amidation approach to 3- -2-indolinones 显示文摘 | Manley JM Kalman M J Conway BG | 2003 | J Org Chem2003，68，16： | 1 |
| 20 | A New Approach to Linear Filtering and Prediction Problems 显示文摘 | Kalman R E | 1960 | Trans ASME Journal of Basic Engineering1960，82，01： | 1 |
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