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您的检索式：作者名="Chimowitz M."
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| 1 | 代谢综合征对症状性脑内动脉狭窄预后的影响显示文摘Background: The metabolic syndrome (MetS) is a cluster of risk factors linked to insulin resistance that increase an individual’s risk of atherosclerotic vascular disease. The authors evaluated the prevalence and prognosis of the MetS among individuals with symptomatic intracranial arterial stenosis. Methods: Patients enrolled in the Warfarin-Aspirin Symptomatic Intracranial Disease trial were evaluated in this post-hoc analysis. Baseline characteristics and outcome were compared in patients with the MetS vs patients without the MetS. Results: Among 476 patients, the prevalence of the MetS was 43%. MetS patients were more likely to be younger, female, and white. During a mean follow-up period of 1.8 years, time to the first of ischemic stroke, myocardial infarction, or vascular death was shorter among patients with the MetS with a hazard ratio (syndrome/no syndrome) of 1.6 (95%CI = 1.1 to 2.4, p = 0.0097). Time to ischemic stroke alone was also shorter among patients with the MetS with a hazard ratio (syndrome/no syndrome) of 1.7 (95%CI = 1.1 to 2.6, p = 0.012). When controlling for individual factors of the definition, MetS was not significant (combined outcome: p = 0.14; ischemic stroke: p = 0.074). Conclusions: The metabolic syndrome is present in about half of individuals with symptomatic intracranial atherosclerotic disease and is associated with a substantially higher risk of major vascular events. The metabolic syndrome may not provide additional ability to predict outcomes beyond the individual factors for patients with intracranial stenosis. | Ovbiagele B. Saver J. L. Lynn M. J. Chimowitz M. 邱伟庆(译) | 2006 | 世界核心医学期刊文摘(神经病学分册)2006，2，9： | 12 |
| 2 | 卒中和短暂性脑缺血发作患者的卒中预防指南(续前)美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南显示文摘5非心源性栓塞性卒中或TIA的抗栓治疗
5.1抗血小板药
FDA已批准4种抗血小板药用于预防卒中或TIA患者的血管事件:阿司匹林、阿司匹林/双嘧达莫联合应用、氯吡格雷和噻氯匹定。平均而言,这些药物能使卒中、MI或死亡的船降低22%,但这些药物之间存在重要的差异,这会直接影响治疗的选择。 | 洪道俊 黄招君 李小兵 周美鸿 吴成斯 王博 卢艺 吴裕臣 Walter N. Kernan Bruce Ovbiagele Henry R. Black Dawn M. Bravata Marc I. Chimowitz Michael D. Ezekowitz Margaret C. Fang Marc Fisher Karen L. Furie Donald V. Heck S. Claiborne (Clay) Johnston Scott E. Kasner Steven J. Kittner Pamela H. Mitchell 2. .. Michael wl Rich DeJuran .Nchardson Lee H. Schwamm John A. Wilson | 2014 | 国际脑血管病杂志2014，22，12： | 1 |
| 3 | Transcranial Doppler ultrasound identifies patients with right-to-left cardiac or pulmonary shunts显示文摘 | M. I. Chimowitz J. J. Nemec T. H. Marwick R. J. Lorig A. J. Furlan E. E. Salcedo | 1991 | Neurology1991，，12： | 1 |
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