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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | What are the ten new commandments in severe polytrauma management?显示文摘 | CW Kam CH Lai SK Lam FL So CL Lau KH Cheung | 2010 | World Journal of Emergency Medicine2010，1，2： | 9 |
| 3 | Lumbar intrathecal administration of the quaternary lidocaine derivative, QX-314, produces irritation and death in mice显示文摘 | Schwarz SK Cheung HM Ries CR | 2010 | Anesthesiology2010，113，2： | 1 |
| 4 | Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease显示文摘 | Baum L Lam CW Cheung SK | 2008 | J Clin Psychopharmacol2008，28，1： | 1 |
| 5 | Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcum- in in patients with Alzheimer disease显示文摘 | Baum L Lam CW Cheung SK | 2008 | J Clin Psychopharma- col2008，28，1： | 1 |
| 6 | Astigmatism in Chinese preschool children:prevalence,change,and effect on refractive development显示文摘 | Fan DS Rao SK Cheung EY Islam M Chew S Lain DS | | 0，，07： | 1 |
| 7 | TH1 and TH2 cytokine mRNA profile in childhood nephrotic syndrome: evidence for increased IL-13 mRNA expression in relapse显示文摘 | Yap HK Cheung W Murugasu B Sim SK Seah CC Jordan SC | 1999 | J Am Soc Nephrol1999，10，3： | 1 |
| 8 | Gonadoblastoma in patient with Tumer's syndrome 显示文摘 | Lo KW Lam SK Cheung TH | 1996 | J Obstet Gynaecol1996，22，： | 1 |
| 9 | Guidelines on timing in replacing peripheral intravenous catheters显示文摘 | Ken HM Ho Daphne SK Cheung | 2012 | Journal of Clinical Nursing2012，21，： | 1 |
| 10 | Burnout among public doctors in Hong Kong: cross-sectional survey 显示文摘 | Siu CF Yuen SK Cheung A | 2012 | Hong Kong Med J2012，18，3： | 1 |
| 11 | Astigmatism in Chinese preschool children: Prevalence, change, and effect on refractive de- velopment 显示文摘 | FAN DS RAO SK CHEUNG EY | 2004 | Br J Ophthalmol2004，88，7： | 1 |
| 12 | Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells显示文摘 | Chung LY Cheung TC Kong SK | 2001 | Life sciences2001，68，10： | 1 |
| 13 | Abnormal peri-pubertal anthropometric measurements and growth pattern in adolescent idiopathic scoliosis:a study of 598 patients显示文摘 | Cheung SK Lee TK Tse K | 2003 | Spine2003，28，18： | 1 |
| 14 | Intracardiac thrombus: a risk of incomplete anticoagulation for cardiac operations显示文摘 | Levin SK Weiss SJ | 1994 | Ann Thorac Surg1994，58，： | 1 |
| 15 | Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic显示文摘 | Smith GJ Vijaykrishna D Bahl J Lycett SJ Worobey M Pybus OG Ma SK Cheung CL Raghwani J Bhatt S Peiris JS Guan Y Rambaut A | 2009 | Nature2009，459，7250： | 1 |
| 16 | Assessment of optimistic selfbeliefs:further validation of the Chinese version of the General Self-efficacy Scale显示文摘 | Cheung SK Sun SY | 1999 | Psychol Rep1999，85，32： | 1 |
| 17 | Low-intensity pulsed ultrasound accelerated callus formation,angiogenesis and callus remodeling in osteoporotic fracture healing显示文摘 | Cheung WH Chow SK Sun MH | 2011 | Ultrasound Med Biol2011，37，2： | 1 |
| 18 | Linear and nonlinear processes in twodimensional mixing layer dynamics and sound radiation显示文摘 | Cheung LC Lele SK | | 0，，： | 1 |
| 19 | Education and counseling of pregnant patients with chronic hepatitis B:perspectives from obstetricians and perinatal nurses in Santa Clara County,California显示文摘 | Yang EJ Cheung CM So SK | 2013 | Asian Pac J Cancer Prev2013，14，3： | 1 |
| 20 | Assessment of optimistic self-beliefs: further validation of the Chinese version of the General Self-Efficacy Scale 显示文摘 | Cheung SK Sun SY | 1999 | Psychol Rep1999，85，32： | 1 |
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