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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | What are the ten new commandments in severe polytrauma management?显示文摘 | CW Kam CH Lai SK Lam FL So CL Lau KH Cheung | 2010 | World Journal of Emergency Medicine2010，1，2： | 9 |
| 3 | High-intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients awaiting liver transplantation显示文摘The scarcity of liver grafts in Asia leads to a significant dropout of patients from liver transplant waiting lists, particularly patients with hepatocellular carcinoma and a low model for end-stage liver disease score. In order to reduce dropping out, different bridging therapies are employed. We report the use of high-intensity focused ultrasound ablation as a bridging therapy for a patient with hepatocellular carcinoma of stage two and an extremely low platelet count (20×10 9 /L). The ablation was successful. Blood tests showed that his liver function was similar before and after the treatment. No adhesion was encountered in the liver transplantation performed six months later. | Tan To Cheung Kenneth SH Chok Regina CL Lo William W Sharr See Ching Chan Ronnie TP Poon Sheung Tat Fan Chung Mau Lo | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，5： | 3 |
| 4 | Reduced serum beta - trace protein is associated with metabolic syndrome显示文摘 | Cheung CL Cheung TT Lam KS | 2013 | Athewscle- resis2013，227，2： | 1 |
| 5 | The insomnia patient perspective, a narrative review 显示文摘 | Cheung JM Bartlett D J Armour CL | 2013 | Behav Sleep Med2013，11，5： | 1 |
| 6 | Use of 3-dimensional printing technology and silicone modeling in surgical simulation: development and face validation in pediatric laparoscopic pyelo- plasty 显示文摘 | Cheung CL Looi T Lendray TS | 2014 | J Surg Educt2014，71，5： | 1 |
| 7 | Atopy,serum IgE,and interleukin-13 in steroid-responsive nephritic syndrome显示文摘 | Cheung W Wei CL Seah CC | 2004 | Pediatr Nephrol2004，19，6： | 1 |
| 8 | A Chinese patient with severe Tako-Tsubo cardiomyopathy显示文摘 | Tsui PT Cheung KC Lau CL | 2007 | Int J Cardiol2007，119，1： | 1 |
| 9 | A comparison of dexmedetomidine and midazolam for sedation in third molar surgery显示文摘 | CHEUNG CW YING CL CHIU WK et d | 2007 | Anaesthesia2007，62，11： | 1 |
| 10 | Anterior approach versus conventional approach right hepatic resection for large hepatocellular carcinoma:a prospective randomized controlled study显示文摘 | Liu CL Fan ST Cheung ST | 2006 | Ann Surg2006，244，2： | 1 |
| 11 | Anterior approach versus conventional approach right hepatic resection for large hepato- cellular carcinoma: a prospective randomized controlled study 显示文摘 | Liu CL Fan ST Cheung ST et at | 2006 | Ann Surg2006，244，2： | 1 |
| 12 | Metabolic profiling of meat:assessment of pork hygiene and contamination with Salmonella typhimurium 显示文摘 | Xu Y Cheung W Winder CL | 2011 | Analyst2011，136，3： | 1 |
| 13 | Anterior approach versus conventional approach right hepatic resection for large hepatocellular carcinoma:a prospective randomized controlled study显示文摘 | Liu CL Fan ST Cheung ST | | 0，，02： | 1 |
| 14 | Direct haplotypiing of kilobase- size DNA using carbon namotube probes显示文摘 | Wooley AT Guillemette C Cheung CL | 2000 | Nat Biotechnol2000，18，7： | 1 |
| 15 | Association of CDX1 bindingsite of periostin gene with bone mineral density and vertebral fracturerisk显示文摘 | Xiao SM Gao Y Cheung CL | 2012 | Osteoporos Int2012，23，7： | 1 |
| 16 | Anterior approach versus conventional approach right hepatic resection for large hepatocellular carcinoma:a prospective randomized controlled study显示文摘 | Liu CL Fan ST Cheung ST | 2006 | Ann Surg2006，244，2： | 1 |
| 17 | Identification of QTL genes for BMD variation using both linkage and gene-based association approaches 显示文摘 | Li GH Cheung CL Xiao SM | 2011 | Hum Genet2011，130，4： | 1 |
| 18 | Tranexamic acidassociated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas 显示文摘 | Ip PP Lam KW Cheung CL | 2007 | Am J Surg Pathol2007，31，8： | 1 |
| 19 | Novel anterior-chamber angle measurements by high-definitlon optical coherence tomography using the schwalbe line as the landmark 显示文摘 | Cheung CY Zheng C Ho CL | 2011 | Br J Ophthalmol2011，95，7： | 1 |
| 20 | Structural and functional imaging with carbon nanotue AFM probes显示文摘 | Hafner JH Cheung CL Woolley AT | 2001 | Prog Biophys Mol Biol2001，77，1： | 1 |
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