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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Expression of the cystic fibrosis transmembrane conductance regulator in rat spermatids: implication for the site of antispermatogenic agents显示文摘 | Gong X D Li J C Cheung K H | 2001 | Mol Hum Reprod2001，7，8： | 2 |
| 3 | Recent advances in nonalcoholic fatty liver disease显示文摘 | Onpan Cheung Arun J Sanyal | 2010 | Current Opinion in Gastroenterology2010，，3： | 2 |
| 4 | Effects of U50,488H on transient outward and ultra-rapid delayed rectifier K+ currents in young human atrial myocytes显示文摘 | Xiao G S Zhou J J Cheung Y F | 2003 | Eur J Pharmacol2003，473，： | 2 |
| 5 | Cervical Intervertebral Disc Degeneration Induced by Unbalanced Dynamic and Static Forces: A Novel In Vivo Rat Model显示文摘 | Yong-Jun Wang Qi Shi W W. Lu K C. M. Cheung Michael Darowish Tian-Fang Li Yu-Feng Dong Chong-Jian Zhou Quan Zhou Zhi-jun Hu Mei Liu Qin Bian Chen-Guang Li K D. K. Luk J C. Y. Leong | 2006 | Spine2006，，14： | 2 |
| 6 | Fractal analysis of leaf shapes显示文摘 | Vlcek J Cheung E | 1986 | Can J For Res1986，16，： | 2 |
| 7 | Recent advances in nonalcoholic fatty liver disease显示文摘 | Onpan Cheung Arun J Sanyal | 2009 | Current Opinion in Gastroenterology2009，，3： | 2 |
| 8 | Nitrogen and phosphorus leaching from fertilizer applied on golf course: Lysimeter study 显示文摘 | Wong J W C Chan C W Y Cheung K G | 1998 | Water Air and Soil Pollution1998，107，： | 1 |
| 9 | Indigenous Chinese personality constructs: Is the five factor model complete? 显示文摘 | CHEUNG F M LEUNG K ZI-IANG J X | 2001 | J Cross Cultural Psychol2001，32，40： | 1 |
| 10 | Determination of pesticides in apple-based infant foods using liquid chromatography electrospray ionization tandem mass spectrometry显示文摘 | WANG J CHEUNG W GRANT D | 2005 | J Agric Food Chem2005，53，3： | 1 |
| 11 | Reexamining the stages of concern questionnaire: A test of alternative models显示文摘 | Cheung D Hattie J Ng D | 2001 | Journal of Educational Research2001，94，4： | 1 |
| 12 | IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6显示文摘 | Yen D Cheung J Scheerens H | 2006 | J Clin Invest2006，116，5： | 1 |
| 13 | Relationshipsbetween tissue concentrations of polycyclic aromatic hydro-carbons and antioxidative responses of marine musselsPerna viridis显示文摘 | Cheung C C C Zheng G J Li A M Y | 2001 | Aquatic Toxicology2001，52，34： | 1 |
| 14 | Sorption kinetic analysis for the removal of cadmium ions from effluents using bone char显示文摘 | CHEUNG C W PORTER J F MCKAY G | 2001 | Water Research2001，35，3： | 1 |
| 15 | Recombinant human tumor necrosis factor alpha promotes adherence of Staphylococcus aureus to cultured human endothelial cells 显示文摘 | Cheung A L Koomey J M Lee S | 1991 | Infect Immun1991，59，： | 1 |
| 16 | Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma显示文摘 | Alaminos M Mora J Cheung NK Smith A Qin J Chen L Gerald WL | 2003 | Cancer Res2003，63，8： | 1 |
| 17 | Regulation of exoprotein expression in Staphylococcus aureus by a locus (sat) distinct from agr显示文摘 | Cheung A L Koomey J M Butler C A | 1992 | Proc Natl Acad Sci1992，89，： | 1 |
| 18 | Atherosclerotic cardiovascular disease risks in chronic hemodialysis patients显示文摘 | Cheung AK Samak M J Yah G | 2000 | Kidney Int2000，58，1： | 1 |
| 19 | Morphometric study of the apical anatomy of C-shaped root canal systems in mandibular second molars显示文摘 | Cheung GS Yang J Fan B | 2007 | Int Endod J2007，40，4： | 1 |
| 20 | Transapical transcatheter atric valve implantation in humans:initial clinical experience显示文摘 | Lichtein SV Cheung A Ye J | | Circulation0，，： | 1 |
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