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| 1 | Insult of gastroesophageal reflux on airway: clinical significance of pharyngeal nozzle显示文摘在到最糟的最高的注意在航线上吸烟以及薄雾侮辱的全球付钱的时间,所有人知道两个外长、显著。然而,包括许多医药人员,人们主要不知道 gastroesophageal 倒流(GER ) 怎么糟糕在我们的自己的航线上侮辱。GER 的症状通常被看作心痛和流回,它能主要被容忍。不管多么起来在它出现的地方,去的胃的内容相对地传递食管然后远侧的咽象苛评一样的鸟喙,用作一张嘴,以便生产众多微粒子并且到达oro鼻的洞并且另外引起的航线过敏鼻炎和气喘的攻击,甚至肺的实质损害。它将减少生活质量或甚至使受危险生活。内长的侮辱在呼吸系统出现,但是从消化的道发源的点不是众所周知的并且经常 undiagnosed 并且不正确地对待。导致的航线挑战是的 GER 一个可对待、预防的实体一旦诊断被做,好消除能通过 radiofrequency 或 fundoplication 借助于张开的贲门的生活方式调整,药,或固定被期望。作者王忠高博士承受了它为长并且症状在反倒流外科以后消失了 8 年。这是王忠高博士和他的队工作的一个演讲并且将引起注意到公众以便认出作为吸烟或薄雾从人的本身,然而并非从外面的环境发生的一个可对待的条件做的这个相对未知的实体。 | Zhonggao Wang Zhiwei Hu Jimin Wu Feng Ji Hongtao Wang Yungang Lai Xiang Gao Yachan Ning Chengchao Zhang Zhitong Li Weitao Liang Jianjun Liu | 2015 | Frontiers of Medicine2015，9，1： | 21 |
| 2 | Artemisinin, the Magic Drug Discovered from Traditional Chinese Medicine显示文摘Artemisinin and its derivatives represent the most important and influential class of drugs in the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global community has made great strides in characterizing and understanding this remarkable phytochemical and its unique chemical and pharmacological properties. Today, even as artemisinin continues to serve as the foundation for antimalarial therapy, numerous challenges have surfaced in the continued application and development of this family of drugs. These challenges include the emergence of delayed treatment responses to artemisinins in malaria and efforts to apply artemisinins for non-malarial indications. Here, we provide an overview of the story of artemisinin in terms of its past, present, and future. In particular, we comment on the current understanding of the mechanism of action (MOA) of artemisinins, and emphasize the importance of relating mechanistic studies to therapeutic outcomes, both in malarial and non-malarial contexts. | Jigang Wang Chengchao Xu Yin Kwan Wong Yujie Li Fulong Liao Tingliang Jiang Youyou Tu | 2019 | Engineering2019，5，1： | 16 |
| 3 | Fragmentation characteristics analysis of sandstone fragments based on impact rockburst test显示文摘Impact rockburst test on sandstone samples with a central hole is carried out under true triaxial static loads and vertical dynamic load conditions,and rock fragments after the test are collected.The fragments of sandstone generated from strain rockburst test and uniaxial compression test are also collected.The fragments are weighed and the length,width and thickness of each piece of fragments are measured respectively.The fragment quantities with coarse,medium,fine and micro grains in different size ranges,mass and particles distributions are also analyzed.Then,the fractal dimension of fragments is calculated by the methods of size-frequency,mass-frequency and length-to-thickness ratio-frequency.It is found that the crushing degree of impact rockburst fragments is higher,accompanied with blocky characteristics observably.The mass percentage of small grains,including fine and micro grains,in impact rockburst test is higher than those in strain rockburst test and uniaxial compression test.Energy dissipation from rockburst tests is more than that from uniaxial compression test,as the quantity of micro grains generated does. | Dongqiao Liu Dejian Li Fei Zhao Chengchao Wang | 2014 | Journal of Rock Mechanics and Geotechnical Engineering2014，6，3： | 8 |
| 4 | IGHG1 promotes motility likely through epithelial-mesenchymal transition in ovarian cancer显示文摘Objective: Ovarian cancer(OC) is one of the leading causes of death for female cancer patients. COC166-9 is an OC-specific monoclonal antibody and we have identified immunoglobulin γ-1 heavy chain constant region(IGHG1) as its antigen. We explore the function of IGHG1 in proliferation, apoptosis and motility of OC cells further in this research.Methods: IGHG1 expression in OC specimens was detected through immunohistochemistry. Real-time quantitative polymerase chain reaction(RT-q PCR) or western blotting assay was used to test IGHG1 expression in OC cells. Viability of OC cells was tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay. Flow cytometry or western blotting assay was used to detect cell cycle and apoptosis. Cellular motility was analyzed by using transwell assay and the markers of epithelial-mesenchymal transition(EMT) were tested through immunoblots.Results: Although it exerts negligible effect on the viability and apoptosis of OC cells, IGHG1 could promote migration and invasion of malignant cells in vitro. Mechanistically, IGHG1 increases the expression of N-cadherin and Vimentin while decreases E-cadherin expression. Additionally, IGHG1 expression in OC specimens is higher relative to the paired normal counterparts. Further analysis demonstrates that the increased IGHG1 expression correlates positively with the lymph node metastasis of OC.Conclusions: IGHG1 promotes the motility of OC cells likely through executing the EMT program. Increased IGHG1 expression in OC specimens is associated with the lymph node metastasis. | Jingfeng Qian Fangxing Ji Xue Ye Hongyan Cheng Ruiqiong Ma Xiaohong Chang Chengchao Shou Heng Cui | 2018 | Chinese Journal of Cancer Research2018，30，2： | 6 |
| 5 | Oxyvanite V3O5:A new intercalation-type anode for lithium-ion battery显示文摘In the present study,V3O5 microcrystals that synthesized via vacuum calcination are employed as anodes for lithium-ion batteries(LIBs)for the first time.Despite the widely observed sluggish reaction kinetics and poor cycling stability in most microsized transition metal oxides,the V3O5 microcrystals exhibit excellent rate capability(specific capacities of 144 and 125 mAh g^−1 are achieved at extremely high current densities of 20 and 50 A g^−1,respectively)and long-term cycling performance(specific capacity of 117 mAh g^−1 is sustained over 2000 cycles at 50 A g^−1).It is ascribed to the three-dimensional open-framework structure of the V3O5 microcrystals as a major factor in dictating the fast reaction kinetics(lithium diffusion coefficient:~10−9 cm^2 s^−1).In addition,significant insight into the reaction mechanism of the V3O5 microcrystals in concomitant its phase evolution are obtained from ex-situ XRD study,revealing that the V3O5 microcrystals undergo intercalation reaction with insignificant structural change in response to lithiation/delithiation. | Dong Chen Huiteng Tan Xianhong Rui Qi Zhang Yuezhan Feng Hongbo Geng Chengchao Li Shaoming Huang Yan Yu | 2019 | InfoMat2019，1，2： | 6 |
| 6 | Factors that determine catastrophic expenditure for tuberculosis care: a patient survey in China显示文摘Background:Tuberculosis(TB)often causes catastrophic economic effects on both the individual suffering the disease and their households.A number of studies have analyzed patient and household expenditure on TB care,but there does not appear to be any that have assessed the incidence,intensity and determinants of catastrophic health expenditure(CHE)relating to TB care in China.That will be the objective of this paper.Methods:The data used for this study were derived from the baseline survey of the China Government–Gates Foundation TB Phase Ⅱ program.Our analysis included 747 TB cases.Catastrophic health expenditure for TB care was estimated using two approaches,with households defined as experiencing CHE if their annual expenditure on TB care:(a)exceeded 10%of total household income;and(b)exceeded 40%of their non-food expenditure(capacity to pay).Chi-square tests were used to identify associated factors and logistic regression analysis to identify the determinants of CHE.Results:The incidence of CHE was 66.8%using the household income measure and 54.7%using non-food expenditure(capacity to pay).An inverse association was observed between CHE rates and household income level.Significant determinants of CHE were:age,household size,employment status,health insurance status,patient income as a percentage of total household income,hospitalization and status as a minimum living security household.Factors including gender,marital status and type of TB case had no significant associations with CHE.Conclusions:Catastrophic health expenditure incidence from TB care is high in China.An integrated policy expanding the free treatment package and ensuring universal coverage,especially the height of UHC for TB patients,is needed.Financial and social protection interventions are essential for identified at-risk groups. | Chengchao Zhou Qian Long Jiaying Chen Li Xiang Qiang Li Shenglan Tang Fei Huang Qiang Sun Henry Lucas | 2016 | Infectious Diseases of Poverty2016，5，1： | 6 |
| 7 | Impairment of the autophagy-lysosomal pathway in Alzheimer’s diseases: Pathogenic mechanisms and therapeutic potential显示文摘Alzheimer’s disease(AD),the most common neurodegenerative disorder,is characterized by memory loss and cognitive dysfunction.The accumulation of misfolded protein aggregates including amyloid beta(Aβ)peptides and microtubule associated protein tau(MAPT/tau)in neuronal cells are hallmarks of AD.So far,the exact underlying mechanisms for the aetiologies of AD have not been fully understood and the effective treatment for AD is limited.Autophagy is an evolutionarily conserved cellular catabolic process by which damaged cellular organelles and protein aggregates are degraded via lysosomes.Recently,there is accumulating evidence linking the impairment of the autophagy-lysosomal pathway with AD pathogenesis.Interestingly,the enhancement of autophagy to remove protein aggregates has been proposed as a promising therapeutic strategy for AD.Here,we first summarize the recent genetic,pathological and experimental studies regarding the impairment of the autophagy-lysosomal pathway in AD.We then describe the interplay between the autophagy-lysosomal pathway and two pathological proteins,Aβand MAPT/tau,in AD.Finally,we discuss potential therapeutic strategies and small molecules that target the autophagy-lysosomal pathway for AD treatment both in animal models and in clinical trials.Overall,this article highlights the pivotal functions of the autophagy-lysosomal pathway in AD pathogenesis and potential druggable targets in the autophagy-lysosomal pathway for AD treatment. | Wei Zhang Chengchao Xu Jichao Sun Han-Ming Shen Jigang Wang Chuanbin Yang | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 6 |
| 8 | Metal-organic frameworks nanoswitch:Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference显示文摘Endo/lysosomal escape and gene release are two critical bottlenecks in gene delivery.Herein,a novel photo-controllable metal-organic frameworks(MOFs)nanoswitch is rationally designed for enhancing small interfering RNA(siRNA)delivery.One single laser triggers the“off-to-on”switching of MOFs nanocomplexes,inducing significant siRNA release accompanied by rapid MOFs dissociation into protonatable 2-methylimidazalo and osmotic rupturing Zn2+ions,which cooperatively contribute to remarkable endo/lysosomal rupture(∼90%).The simultaneous endo/lysosomal rupture and release enable a high spatio-temporal control on RNA interference for effective cancer therapy.Notably,the“off-to-on”switching also activates fluorescence recovery for real-time monitoring siRNA delivery.The nanoswitch could easily be extended to deliver other therapeutic agents(e.g.,DNA,protein,anticancer drug)for overcoming endo/lysosomal entrapment. | Gan Lin Yang Zhang Long Zhang Junqing Wang Ye Tian Wen Cai Shangui Tang Chengchao Chu JiaJing Zhou Peng Mi Xiaoyuan Chen Gang Liu | 2020 | Nano Research2020，13，1： | 5 |
| 9 | RING finger protein RGLG1 and RGLG2 negatively modulate MAPKKK18 mediated drought stress tolerance in Arabidopsis显示文摘Mitogen activated protein kinase kinase kinase 18(MAPKKK18)mediated signaling cascade plays important roles in Arabidopsis drought stress tolerance.However,the post-translational modulation patterns of MAPKKK18 are not characterized.In this study,we found that the protein level of MAPKKK18 was tightly controlled by the 26 S proteasome.Ubiquitin ligases RGLG1 and RGLG2 ubiquitinated MAPKKK18 at lysine residue K32 and K154,and promoted its degradation.Deletion of RGLG1 and RGLG2 stabilized MAPKKK18 and further enhanced the drought stress tolerance of MAPKKK18-overexpression plants.Our data demonstrate that RGLG1 and RGLG2 negatively regulate MAPKKK18-mediated drought stress tolerance in Arabidopsis. | Jiayi Yu Lu Kang Yuanyuan Li Changai Wu Chengchao Zheng Pei Liu Jinguang Huang | 2021 | Journal of Integrative Plant Biology2021，63，3： | 4 |
| 10 | The mechanism underlying overwintering death in poplar:the cumulative effect of effective freeze-thaw damage显示文摘We analyzed the relationships linking overwintering death and frost cracking to temperature and sunlight as well as the effects of low temperatures and freeze–thaw cycles on bud-burst rates,relative electrical conductivity,and phloem and cambial ultrastructures of poplar.Overwintering death rates of poplar were not correlated with negative accumulated temperature or winter minimum temperature.Freeze–thaw cycles caused more bud damage than constant exposure to low temperatures.Resistance to freeze–thaw cycles differed among clones,and the budburst rate decreased with increasing exposure to freeze–thaw cycles.Cold-resistant clones had the lowest relative electrical conductivity.Chloroplasts exhibited the fastest and the most obvious reaction to freeze–thaw damage,whereas a single freeze–thaw cycle caused little damage to cambium ultrastructure.Several such cycles resulted in damage to plasma membranes,severe damage to organelles,dehydration of cells and cell death.We conclude that overwintering death of poplar is mainly attributed to the accumulation of effective freeze–thaw damage beyond the limits of freeze–thaw resistance. | Chengchao Yang Jiandong Peng Xiaoyu Li Dejun Liang Zhiyan Yang Yan Zhang | 2020 | Journal of Forestry Research2020，31，1： | 4 |
| 11 | The blooming intersection of transcatheter hepatic artery chemoembolization and nanomedicine显示文摘Transcatheter hepatic artery chemoembolization(TACE)is a universal treatment for patients with hepatocellular carcinoma(HCC)that inhibits tumor growth by cutting off the blood supply and provides chemotherapeutics locally to the tumor.The strategy of combining TACE formulation with image-guided ablation holds tremendous potential,but patient tolerance and undesired toxicity/immunosuppression remains a challenge.The application of nanotechnology in TACE opens new doors for the treatment of HCC.Strikingly,nanomaterials or nano-drugs dispersed in the TACE formulation can effectively improve the delivery efficiency of drugs by achieving both controlled and continuous release.In addition,the utilization of multifunctional nanoparticles can provide guidance and monitoring for various advanced imaging methods for TACE treatment,and can realize the combination therapy of thermal ablation,microwave ablation,in situ radiotherapy,and other therapies,greatly expanding the therapeutic strategies available for HCC treatment.Here,the current exploration of nanotechnology in TACE of HCC is briefly summarized and the challenges of TACE with nanoformulations for clinical translation are comprehensively discussed. | Hu Chen Hongwei Cheng Wenying Wu Dengfeng Li Jingsong Mao Chengchao Chu Gang Liu | 2020 | Chinese Chemical Letters2020，31，6： | 4 |
| 12 | Environmentally responsive dual-targeting nanotheranostics for overcoming cancer multidrug resistance显示文摘The development of multiple drug resistance(MDR) to chemotherapy and subsequent treatment failures are major obstacles in cancer therapy. An attractive option for combating MDR is inhibiting the expression of P-glycoprotein(P-gp) in tumor cells. Here, we report a novel chemosensitizing agent, XMD8-92,which can down-regulate P-gp. To enhance the specificity of MDR chemotherapy, a promising nanotheranostic micelle system based on poly(ethylene glycol)-blocked-poly(L-leucine)(PEG-b-Leu) was developed to simultaneously carry the anticancer drug doxorubicin, chemosensitizing agent XMD8-92, and superparamagnetic iron oxide nanoparticles(SPIOs). Featured with MDR environmentally responsive dual-targeting capability, controllable drug delivery, and efficient magnetic resonance(MR) imaging characteristics, the prepared nanotheranostics(DXS@NPs) showed outstanding in vitro cytotoxicity on MDR cells(SCG 7901/VCR) with only 53% of cells surviving compared to 90% of DOX-treated cells.Furthermore, efficient tumor inhibition and highly reduced systemic toxicity were exhibited by MDR tumor-bearing mice treated with DXS@NPs. Overall, the environmentally responsive dual-targeting nanotheranostics represent a promising approach for overcoming cancer MDR. | Caixia Yang Xin Pang Weihai Chen Xiaoyong Wang Gan Lin Chengchao Chu Xianzheng Zhang Xianming Deng Xiaoyuan Chen Gang Liu | 2019 | Science Bulletin2019，64，10： | 3 |
| 13 | High level of serum AMBP is associated with poor response to paclitaxel–capecitabine chemotherapy in advanced gastric cancer patients显示文摘 | Hao Huang Yong Han Jing Gao Junnan Feng Lei Zhu Like Qu Lin Shen Chengchao Shou | 2013 | Medical Oncology2013，，4： | 3 |
| 14 | Protein P37 of mycoplasma hyorhinis induces secretion of TNF-αfrom human peripheral blood mononuclear cells显示文摘High mycoplasmal infection ratio in gastric cancer tissues suggests a possible association between my-coplasma infection and tumorigenesis. Because TNF-a plays an important role in carcinogenesis caused by microbes in-fection and P37 is a major immunogen of mycoplasma hy-orhinis (M. hyor.), investigating whether P37 could induceexpression and secretion of TNF-a will be very significant to elucidate the possible molecular mechanism of gastric car-cinogenesis involved with M. hyor. At the present study, we cloned full gene of p37 by PCR and mutated the 7 codes of TGA into TGG firstly, then expressed the P37 protein suc-cessfully with pGEX-4T-1 vector in E. coli, which was veri-fied with Western blot. By RT-PCR and sensitive L929 cell toxic assay, we found that P37 protein could induce expres-sion and secretion of TNF-a from human peripheral bloodmononuclear cells, and the inducing activity of P37 could be dramatically blocked by McAb PD4. These results suggestthat the induction of TNF-a secretion by P37 probably plays an important role in diseases caused by M. hyor. infectionand needs to be further investigated. | NING Jinying, HUANG Su, WU Jian, MENG Lin & SHOU Chengchao Department of Biochemistry and Molecular Biochemistry, School ofOncology, Peking University and Beijing Institute for Cancer Research, Beijing 100034, China | 2003 | Chinese Science Bulletin2003，48，7： | 3 |
| 15 | Responses of calcareous sand foundations to variations of groundwater table and applied loads显示文摘The long-term settlement of calcareous sand foundations caused by daily periodic fluctuations has become a significant geological hazard,but effective monitoring tools to capture the deformation profiles are still rarely reported.In this study,a laboratory model test and an in situ monitoring test were conducted.An optical frequency domain reflectometer(OFDR)with high spatial resolution(1 mm)and high accuracy(10-6)was used to record the soil strain responses to groundwater table and varied loads.The results indicated that the fiber-optic measurements can accurately locate the swelling and compressive zones.During the loading process,the interlock between calcareous sand particles was detected,which increased the internal friction angle of soil.The foundation deformation above the sliding surface was dominated by compression,and the soil was continuously compressed beneath the sliding surface.After 26e48 h,calcareous sand swelling occurred gradually above the water table,which was primarily dependent on capillary water.The swelling of the soil beneath the groundwater table was completed rapidly within less than 2 h.When the groundwater table and load remain constant,the compression creep behavior can be described by the Yasong-Wang model with R2¼0.993.The daily periodically varying in situ deformation of calcareous sand primarily occurs between the highest and lowest groundwater tables,i.e.4.2e6.2 m deep.The tuff interlayers with poor water absorption capacity do not swell or compress,but they produce compressive strain under the influence of deformed calcareous sand layers. | Dingfeng Cao Sanjay Kumar Shukla Linqing Yang Chengchao Guo Jinghong Wu Fuming Wang | 2022 | Journal of Rock Mechanics and Geotechnical Engineering2022，14，4： | 2 |
| 16 | Isolation of a strong matrix attachment region (MAR) and identification of its function in vitro and in vivo显示文摘Inclusion of MARs in transgene cassettes enhances their expression and reduces position-effect variations in the transgenic host. Four new MARs (TM2, TM3, AM1 and AM2) were isolated from tobacco and Arabidopsis by PCR method. The nuclei isolated from suspension-cultured cells of rice were used to prepare nuclear matrix. With a characterized MAR (TM1) as a positive control, the Matrix-MAR interactions were tested by an in vitro binding assay to identify the DNA sequences as MARs and their binding strength to nuclear matrix in vitro was compared. The results showed that TM2 and TM3 had stronger binding strength than TM1. To determine the functions of the four new MARs in vivo, binary vectors pBI121 carrying a uidA GUS reporter gene were modified with direct repeat MARs inserted on both sides of the reporter gene cassette and were transferred into tobaccos via Agrobacterium-mediated transformation procedure. Quantitative GUS assays of the transgenic tobaccos showed that when flanking a GUS reporter gene | Kewei Zhang Jianmei Wang Guodong Yang Xingqi Guo Fujiang Wen Decai Cui Chengchao Zheng | 2002 | Chinese Science Bulletin2002，47，23： | 2 |
| 17 | Using of Key Stratum Theory to Study the Structural Development of Roof Aquifer显示文摘During the underground mining of coal resources,overlying rocks on the roof of excavated tunnels will be destroyed due to ground pressure,and as a result,part of them will break and fall into the tunnels.How to determine the distribution of fractured areas and fissures presents a major problem for preserving the overlying aquifer.In most cases,the distribution of fissures | CHEN Li ZHANG Fawang YAO Hongchao HAN Zhantao QIAN Long CHEN Liang JIANG Chengchao | 2015 | Acta Geologica Sinica(English Edition)2015，89，6： | 2 |
| 18 | Regulation of the stability and ABA import activity of NRT1.2/NPF4.6 by CEPR2-mediated phosphorylation in Arabidopsis显示文摘Abscisic acid(ABA)transport plays an important role in systemic plant responses to environmental factors.However,it remains largely unclear about the precise regulation of ABA transporters in plants.In this study,we show that the C-terminally encoded peptide receptor 2(CEPR2)directly interacts with the ABA transporter NRT1.2/NPF4.6.Genetic and phenotypic analyses revealed that NRT1.2/NPF4.6 positively regulates ABA response and that NRT1.2/NPF4.6 is epistatically and negatively regulated by CEPR2.Further biochemical assays demonstrated that CEPR2 phosphorylates NRT1.2/NPF4.6 at serine 292 to promote its degradation under normal conditions.However,ABA treatment and non-phosphorylation at serine 292 prevented the degradation of NRT1.2/NPF4.6,indicating that ABA inhibits the phosphorylation of this residue.Transport assays in yeast and Xenopus oocytes revealed that non-phosphorylated NRT1.2/NPF4.6 had high levels of ABA import activity,whereas phosphorylated NRT1.2/NPF4.6 did not import ABA.Analyses of complemented nrt1.2 mutants that mimicked non-phosphorylated and phosphorylated NRT1.2/NPF4.6 confirmed that non-phosphorylated NRT1.2S292A had high stability and ABA import activity in planta.Additional experiments showed that NRT1.2/NPF4.6 was degraded via the 26S proteasome and vacuolar degradation pathways.Furthermore,we found that three E2 ubiquitin-conjugating enzymes,UBC32,UBC33,and UBC34,interact with NRT1.2/NPF4.6 in the endoplasmic reticulum and mediate its ubiquitination.NRT1.2/NPF4.6 is epistatically and negatively regulated by UBC32,UBC33,and UBC34 inplanta.Taken together,these results suggest that the stability and ABA import activity of NRT1.2/NPF4.6 are precisely regulated by its phosphorylation and degradation in response to environmental stress. | Lei Zhang Zipeng Yu Yang Xu Miao Yu Yue Ren Shizhong Zhang Guodong Yang Jinguang Huang Kang Yan Chengchao Zheng Changai Wu | 2021 | Molecular Plant2021，14，4： | 2 |
| 19 | Discovery and repurposing of artemisinin显示文摘Malaria is an ancient infectious disease that threatens millions of lives globally even today.The discovery of artemisinin,inspired by traditional Chinese medicine(TCM),has brought in a paradigm shift and been recognized as the“best hope for the treatment of malaria”by World Health Organization.With its high potency and low toxicity,the wide use of artemisinin effectively treats the otherwise drug-resistant parasites and helps many countries,including China,to eventually eradicate malaria.Here,we will first review the initial discovery of artemisinin,an extraordinary journey that was in stark contrast with many drugs in western medicine.We will then discuss how artemisinin and its derivatives could be repurposed to treat cancer,inflammation,immunoregulation-related diseases,and COVID-19.Finally,we will discuss the implications of the“artemisinin story”and how that can better guide the development of TCM today.We believe that artemisinin is just a starting point and TCM will play an even bigger role in healthcare in the 21st century. | Qiaoli Shi Fei Xia Qixin Wang Fulong Liao Qiuyan Guo Chengchao Xu Jigang Wang | 2022 | Frontiers of Medicine2022，16，1： | 2 |
| 20 | Chinese manufacturing on the move: Factor supply or market access?显示文摘 | Chengchao Bao Zhao Chen Jianfeng Wu | 2012 | China Economic Review2012，，： | 1 |
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