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| 1 | Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism显示文摘 | Fu YS Cheng YC Lin MY Cheng H Chu PM Chou SC Shih YH Ko MH Sung MS | 2006 | 中国生物学文摘2006，20，10： | 138 |
| 2 | OsWRKY03, a rice transcriptional activator that functions in defense signaling pathway upstream of OsNPR1显示文摘WRKY family proteins are a class of plant specific transcription factors that involve in many stress response pathways. It has been shown that one Arabidopsis WRKY protein, AtWRKY29/22, is activated by MAP kinase signaling cascade and confers resistance to both bacterial and fungal pathogens. However, little is known about the biological roles of WRKY proteins in rice. In this study, we investigated the expression patterns of rice AtWRKY29/22 homolog, OsWRKY03, under different conditions, and also its possible role involved in plant defense. Our results showed that OsWRKY03 was up-regulated by several defense signaling molecules or different treatments. Further analysis revealed that the expres- sion of OsWRKY03 was light dependent. Transcriptional activation activity of OsWRKY03 was also demonstrated by yeast functional assay. Transient expression of OsWRKY03-GFP fusion protein in onion epidermis cells showed that OsWRKY03 was a nuclear localized protein. OsNPR1 as well as several other pathogenesis-related genes, such as OsPR1b, phenylalanine ammonia-lyase (ZB8) and peroxidase (POX22.3), were induced in OsWRKY03-overexpressing transgenic plants. These results indicated that OsWRKY03 is located upstream of OsNPR1 as a transcriptional activator in salicylic acid (SA)-dependent or jasmonic acid (JA)-dependent defense signaling cascades. | Xiao Qiang LIU Xian Quan BAI Qian QIAN Xiu Jie WANG Ming Sheng CHEN Cheng Cai CHU | 2005 | Cell Research2005，15，8： | 55 |
| 3 | Methanation of carbon dioxide on Ni/ZrO_2-Al_2O_3 catalysts:Effects of ZrO_2 promoter and preparation method of novel ZrO_2-Al_2O_3 carrier显示文摘The novel nickel-based catalysts with a nickel content of 12 wt% were prepared with the zirconia-alumina composite as the supports. The new carriers, ZrO2 improved alumina, were synthesized by three methods, i.e., impregnation-precipitation, co-precipitation, and impregnation method. The catalytic properties of these catalysts were investigated in the methanation of carbon dioxide, and the samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscope (XPS), temperature-programmed reduction (TPR) and temperature-programmed desorption (TPD) techniques. The new catalysts showed higher catalytic activity and better stability than Ni/γ-Al2O3. Furthermore, as a support for new nickel catalyst, the ZrO2-Al2O3 composite prepared by the impregnation-precipitation method was more efficient than the other supports in the methanation of carbon dioxide. The highly dispersed zirconium oxide on the surface of γ-Al2O3 inhibited the formation of nickel aluminate-like phase, which was responsible for the better dispersion of Ni species and easier reduction of NiO species, leading to the enhanced catalytic performance of corresponding catalyst. | Mengdie Cai Jie Wen Wei Chu Xueqing Cheng Zejun Li | 2011 | Journal of Natural Gas Chemistry2011，20，3： | 33 |
| 4 | Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)显示文摘In recent years,as living standards have continued to improve,the number of diabetes patients in China,along with the incidence of complications associated with the disease,has been increasing.Among these complications,diabetic foot disease is one of the main causes of disability and death in diabetic patients.Due to the differences in economy,culture,religion and level of medical care available across different regions,preventive and treatment methods and curative results for diabetic foot vary greatly.In multidisciplinary models built around diabetic foot,the timely assessment and diagnosis of wounds and appropriate methods of prevention and treatment with internal and external surgery are key to clinical practice for this pathology.In 2019,under the leadership of the Jiangsu Medical Association and Chinese Diabetes Society,the writing group for the Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease(2020 edition)was established with the participation of scholars from the specialist areas of endocrinology,burn injury,vascular surgery,orthopedics,foot and ankle surgery and cardiology.Drawing lessons from diabetic foot guidelines from other countries,this guide analyses clinical practices for diabetic foot,queries the theoretical basis and grades and gives recommendations based on the characteristics of the pathology in China.This paper begins with assessments and diagnoses of diabetic foot,then describes treatments for diabetic foot in detail,and ends with protections for high-risk feet and the prevention of ulcers.This manuscript covers the disciplines of internal medicine,surgical,nursing and rehabilitation and describes a total of 50 recommendations that we hope will provide procedures and protocols for clinicians dealing with diabetic foot. | Aiping Wang Guozhong Lv Xingbo Cheng Xianghua Ma Wei Wang Jianchao Gui JiHu Meng Lu Guoping Chu Jin’an Chen Hao Zhang Yiqiu Jiang Yuedong Chen Wengbo Yang Lin Jiang Houfa Geng Rendong Zheng Yihui Li Wei Feng Boey Johnson Wenjuan Wang Dalong Zhu Yin Hu | 2020 | Burns & Trauma2020，8，1： | 34 |
| 5 | A novel gene delivery system targeting cells expressing VEGF receptors显示文摘Two ligand oligopeptides GV1 and GV2 were designed according to the putative binding region of VEGF to its receptors. GV1, GV2 and endosome releasing oligopeptide HA20 were conjugated with poly-L-lysine or protamine and the resulting conjugates could interact with DNA in a noncovalent bond to form a complex. Using pSV2-β-galactosidase as a reporter gene, it has been demonstrated that exogenous gene was transferred into bovine aortic arch-derived endothelial cells (ABAE) andhuman malignant melanoma cell lines (A375) in vitro. In vivo experiments, exogenous gene was transferred into tumor vascular endothelial cells and tumor cells of subcutaneously transplanted human colon cancer LOVO, human malignant melanoma A375 and human hepatoma graft in nude mice. This system could also target gene to intrahepatically transplanted human hepatoma injected via portal vein in nude mice. These results are correlated with theGene delivery system targeting VEGF receptors relevant receptors (flt-1, flk-1/KDR) expression on the targeted cells and tissues. | LI JUN MIN JUN SONG HAN YI HUANG PEI KUN TIAN SHU MIN QU MIN YAO HUI QIU JIANG DA FANG WAN JING CHU LUO CHENG XIAO GU JIAN REN GU( National Labomtory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032,China)(National Laboratory of | 1999 | Cell Research1999，9，1： | 22 |
| 6 | Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination显示文摘 | Yiqiang Cui Yuyu Niu Jiankui Zhou Yongchang Chen Yiwei Cheng Shangang Li Zongyong Ai Chu Chu Hong Wang Bo Zheng Xuejin Chen Jiahao Sha Xuejiang Guo Xingxu Huang Weizhi Ji | 2018 | Cell Research2018，28，3： | 13 |
| 7 | LEAFY HEAD2,which encodes a putative RNA-binding protein,regulates shoot development of rice显示文摘在植物的开发期间,更高的植物连续地在常规空间、时间的模式形成新叶子。有反常的叶的异种发展模式不仅提供大卓见进理解植物建筑学的规章的机制,而且充实方法到它庄稼产量能被改进的修正。这里,我们报导了米饭 leafy-head2 (lhd2 ) 的描述展览弄短的异种阶段的 plastochron,侏儒症,减少的 tiller 数字,和失败转移从对繁殖生长植物。而减少的 tiller 数字是 tiller 芽长出的抑制的后果,解剖、组织学的学习表明在 lhd2 的叶子的快速的出现从叶 primordia 的快速的开始被结果。分子、基因的分析证明 LHD2 与 67% 类似编码通常认为的 RNA 有约束力的蛋白质到玉米 TE1。染色体规模表示侧面在之间的比较野类型并且 lhd2 植物建议 LHD2 可以通过 KNOX 和荷尔蒙相关的基因调整米饭射击开发。LHD2 变化和 LHD2 的保存表示模式引起的类似的显型在在草控制时间的叶开始显示了保存机制。 | Guo Sheng Xiong Xing Ming Hu Yong Qing Jiao Yan Chun Yu Cheng Cai Chu Jia Yang Li Qian Qian Yong Hong Wang | 2006 | Cell Research2006，16，3： | 11 |
| 8 | Clinical analysis of multiple primary malignancies in the digestive system: A hospital-based study显示文摘AIM: To analyze the characteristics of multiple primary malignancies (MPMs) of digestive system; including incidence, types of tumor combinations, time intervals between development of multiple tumors, clinical course,and prognostic factors affecting survival and mortality.METHODS: Data from a total of 129 patients treated from January 1991 to December 2000 for pathologically proved MPMs, including at least one originating from the digestive system, were reviewed retrospectively.RESULTS: Among 129 patients, 120 (93.02%) had two primary cancers and 9 (6.98%) had three primary cancers. The major sites of MPMs of the digestive system were large intestine, stomach, and liver. Associated nondigestive cancers included 40 cases of gynecological cancers, of which 31 were carcinoma of cervix and 10cases of genitourinary cancers, of which 5 were bladder cancers. Other cancers originated from the lung, breast,nasopharynx, larynx, thyroid, brain, muscle, and skin.Reproductive tract cancers, especially cervical, ovarian,bladder, and prostate cancers were the most commonly associated non-GI cancers, followed by cancer of the lung and breasts. Forty-three cases were synchronous, while the rest (86 cases) were metachronous cancers. Staging of MPMs and treatment regimes correlated with the prognosis between survival and non-survival groups.CONCLUSION: As advances in cancer therapy bring about a progressively larger percentage of long-term survivors, the proportion of patients with subsequent primary lesions will increase. Early diagnosis of these lesions, based on an awareness of the possibility of second and third cancers, and multidiscipiinary treatment strategies will substantially increase the survival of these patients. | Hui-Yun Cheng Cheng-Hsin Chu Wen-Hsiung Chang Tzu-Chi Hsu Shee-Chan Lin Chuan-Chuan Liu An-Ming Yang Shou-Chuan Shih | 2005 | World Journal of Gastroenterology2005，11，27： | 11 |
| 9 | Detection and fine-mapping of SC7 resistance genes via linkage and association analysis in soybean显示文摘Soybean mosaic virus(SMV) disease is one of the most serious and broadly distributed soybean(Glycine max(L.) Merr.) diseases. Here, we combine the advantages of association and linkage analysis to identify and fine-map the soybean genes associated with resistance to SMV strain SC7.A set of 191 soybean accessions from different geographic origins and 184 recombinant inbred lines(RILs) derived from Kefeng No.1(resistant) Nannong 1138-2(susceptible) were used in this study. The SC7 resistance genes were previously mapped to a 2.65 Mb region on chromosome 2 and a 380 kb region on chromosome 13. Among 19 single nucleotide polymorphisms(SNPs) detected via association analysis in the study, the SNP BARC-021625-04157 was located in the2.65 Mb region, and the SNP BARC-041671-08065 was located near the 380 kb region; three genes harboring the SNPs were probably related to SC7 resistance. The resistance gene associated with BARC-021625-04157 was then finemapped to a region of approximately 158 kb on chromosome2 using 184 RILs. Among the 15 genes within this region, one NBS-LRR type gene, one HSP40 gene and one serine carboxypeptidase-type gene might be candidate SC7 resistance genes. These results will be useful for map-based cloning and marker-assisted selection in soybean breeding programs. | Honglang Yan Hui Wang Hao Cheng Zhenbin Hu Shanshan Chu Guozheng Zhang Deyue Yu | 2015 | Journal of Integrative Plant Biology2015，57，8： | 10 |
| 10 | Spectral characteristic of infrared radiations of some acupoint and non-acupoint areas in human arm surface显示文摘Using infrared spectrum detective device, we experiment on Neiguan, Laogong and Hegu acupoints of seven adult volunteers as well as contrastive points beside ones. We get 63 infrared spectrums. The experiment outcome tells us that the differences of the intensities among individuals are great, and so are the differences between acupoint and non-acupoint areas. However, the differences of spectral character are small, which indicates that infrared radiations of human body are based on the same biophysical fundament. | DING Guanghong YAO Wei CHU Junhao SHEN Xueyong HUANG Zhiming CHENG Huansheng LIU Hui WANG Shenzhang YANG Jing WEI Hu FEI Lun | 2001 | Chinese Science Bulletin2001，46，8： | 9 |
| 11 | Recovery of nickel,cobalt,copper and zinc in sulphate and chloride solutions using synergistic solvent extraction显示文摘A number of synergistic solvent extraction(SSX) systems have been developed to recover nickel,cobalt,zinc and copper from sulphuric and chloride leach solutions by the solvent extraction team of CSIRO,Australia.These include(1) Versatic 10/CLX50 system for the separation of Ni from Ca in sulphate solutions,(2) Versatic 10/4PC system for the separation of Ni and Co from Mn/Mg/Ca in sulphate solutions,(3) Cyanex 471X/HRJ-4277 system for the separation of Zn from Cd in sulphate solutions,(4) Versatic 10/LIX63 system for the separation of Co from Mn/Mg/Ca in sulphate solutions,(5) Versatic 10/LIX63/TBP system for separation of Ni and Co from Mn/Mg/Ca in sulphate solutions,(6) Versatic 10/LIX63 system for the separation of cobalt from nickel in sulphate solutions by difference in kinetics,(7) Cyanex 272/LIX84 system for the separation of Cu/Fe/Zn from Ni/Co in sulphate solutions,(8) Versatic 10/LIX63/TBP system to recover Cu/Ni from strong chloride solutions,and(9) Versatic10/LIX63 system to separate Cu from Fe in strong chloride solutions.The synergistic effect on metal separation and efficiency is presented and possible industrial applications are demonstrated.The chemical stability of selected SSX systems is also reported. | chu yong cheng keith r.barnard wensheng zhang zhaowu zhu yoko pranolo | 2016 | Chinese Journal of Chemical Engineering2016，24，2： | 9 |
| 12 | Uncertainty analysis of hydrological model parameters based on the bootstrap method:A case study of the SWAT model applied to the Dongliao River Watershed,Jilin Province,Northeastern China显示文摘As an important tool for the description and analysis of hydrological processes,the watershed hydrological model has been increasingly applied to watershed hydrological simulations and water resource management.However,in most cases,model parameters are only determined in a calibration scheme which fits the modeled data to observations,thus significant uncertainties exist in the model parameters.How to quantitatively evaluate the uncertainties in model parameters and the resulting uncertainty impacts on model simulations has always been a question which has attracted much attention.In this study,two methods based on the bootstrap method(specifically,the model-based bootstrap and block bootstrap)are used to analyze the parameter uncertainties in the case of the SWAT(Soil and Water Assessment Tool)model applied to a hydrological simulation of the Dongliao River Watershed.Then,the uncertainty ranges of five sensitivity parameters are obtained.The calculated variation coefficients and the variable parameter contributions show that,among the five parameters,ESCO and CN2 have relatively high uncertainties:the variation coefficients and contribution rates are 23.98 and 70%,14.43 and 18%,respectively.The three remaining parameters have relatively low uncertainties.We compare the two uncertainty ranges of parameters acquired by the two bootstrap methods,and find that the uncertainty ranges of parameters acquired by the block bootstrap are narrower than those acquired by the model-based bootstrap.Further analysis of the effects of parameter uncertainties on the model simulation reveals that the parameter uncertainties have great impacts on results of the model simulation,and in the model calibration stage 60%70%of runoff observations were within the corresponding 95%confidence interval.The uncertainty in the model simulation during the flood season(i.e.the wet period)is relatively higher than that during the dry season. | ZHANG Zheng LU WenXi CHU HaiBo CHENG WeiGuo ZHAO Ying | 2014 | Science China(Technological Sciences)2014，57，1： | 9 |
| 13 | Metabolic syndrome and benign prostatic hyperplasia:An update显示文摘Metabolic syndrome(MetS)is a cluster of metabolic abnormalities related to central adiposity and insulin resistance.Its importance is increasingly recognized as it associates with increased risks of metabolic and cardiovascular diseases.These metabolic aberrations of MetS may lead to development of benign prostatic hyperplasia(BPH)and lower urinary tract symptoms(LUTS)in men.A 26.5%-55.6% prevalence of MetS in men with LUTS was reported in worldwide studies.Although the exact biological pathway is not clear yet,insulin resistance,increased visceral adiposity,sex hormone alterations and cellular inflammatory reactions played significant roles in the related pathophysiological processes.Clinician should recognize the cardiovascular and metabolic impacts of MetS in men with LUTS,early risk factors optimization and use of appropriate medical therapy may possibly alter or slower the progression of LUTS/BPH,and potentially avoid unnecessary morbidities and mortalities from cardiovascular and metabolic diseases for those men. | Ho-Yin Ngai Kar-Kei Steffi Yuen Chi-Man Ng Cheung-Hing Cheng Sau-Kwan Peggy Chu | 2017 | Asian Journal of Urology2017，4，3： | 9 |
| 14 | Perirenal space blocking restores gastrointestinal function in patients with severe acute pancreatitis显示文摘AIM:To investigate effects of perirenal space blocking(PSB)on gastrointestinal function in patients with severe acute pancreatitis(SAP).METHODS:Forty patients with SAP were randomly allocated to receive PSB or no PSB(NPSB).All the SAP patients received specialized medical therapy(SMT).Patients in the PSB group received PSB+SMT when hospitalized and after diagnosis,whereas patients in the NPSB group only received SMT.A modifed gastrointestinal failure(GIF)scoring system was used to assess the gastrointestinal function in SAP patients after admission.Pain severity(visual analog scale,0 to100)was monitored every 24 h for 72 h.RESULTS:Modified GIF score decreased in both groups during the 10-d study period.The median score decrease was initially significantly greater in the PSB group than in the NPSB group after PSB was per-formed.During the 72-h study period,pain intensity decreased in both groups.The median pain decrease was significantly greater in the PSB group than in the NPSB group at single time points.Patients in the PSB group had significantly lower incidences of hospital mortality,multiple organ dysfunction syndrome,systemic inflammatory response syndrome,and pancreatic infection,and stayed in the intensive care unit for a shorter duration.However,no difference in terms of operation incidence was found between the two groups.CONCLUSION:PSB could ameliorate gastrointestinal dysfunction or failure during the early stage of SAP.Moreover,PSB administration could improve prognosis and decrease the mortality of SAP patients. | Jun-Jun Sun Zhi-Jie Chu Wei-Feng Liu Shi-Fang Qi Yan-Hui Yang Peng-Lei Ge Xiao-Hui Zhang Wen-Sheng Li Cheng Yang Yu-Ming Zhang | 2013 | World Journal of Gastroenterology2013，19，46： | 8 |
| 15 | Analysis of genetic architecture and favorable allele usage of agronomic traits in a large collection of Chinese rice accessions显示文摘Genotyping and phenotyping large natural populations provide opportunities for population genomic analysis and genome-wide association studies(GWAS). Several rice populations have been re-sequenced in the past decade;however, many major Chinese rice cultivars were not included in these studies. Here, we report large-scale genomic and phenotypic datasets for a collection mainly comprised of 1,275 rice accessions of widely planted cultivars and parental hybrid rice lines from China. The population was divided into three indica/Xian and three japonica/Geng phylogenetic subgroups that correlate strongly with their geographic or breeding origins. We acquired a total of 146 phenotypic datasets for 29 agronomic traits under multi-environments for different subpopulations. With GWAS, we identified a total of 143 significant association loci, including three newly identified candidate genes or alleles that control heading date or amylose content. Our genotypic analysis of agronomically important genes in the population revealed that many favorable alleles are underused in elite accessions, suggesting they may be used to provide improvements in future breeding efforts. Our study provides useful resources for rice genetics research and breeding. | Xiuxiu Li Zhuo Chen Guomin Zhang Hongwei Lu Peng Qin Ming Qi Ying Yu Bingke Jiao Xianfeng Zhao Qiang Gao Hao Wang Yunyu Wu Juntao Ma Liyan Zhang Yongli Wang Lingwei Deng Shanguo Yao Zhukuang Cheng Diqiu Yu Lihuang Zhu Yongbiao Xue Chengcai Chu Aihong Li Shigui Li Chengzhi Liang | 2020 | Science China(Life Sciences)2020，63，11： | 8 |
| 16 | Time-domain solution for transient dynamic response of a large-diameter thin-walled pipe pile显示文摘The propagation of stress waves in a large-diameter pipe pile for low strain dynamic testing cannot be explained properly by traditional 1D wave theories. A new computational model is established to obtain a wave equation that can describe the dynamic response of a large-diameter thin-walled pipe pile to a transient point load during a low strain integrity test. An analytical solution in the time domain is deduced using the separation of variables and variation of constant methods. The validity of this new solution is verifi ed by an existing analytical solution under free boundary conditions. The results of this time domain solution are also compared with the results of a frequency domain solution and fi eld test data. The comparisons indicate that the new solution agrees well with the results of previous solutions. Parametric studies using the new solution with reference to a case study are also carried out. The results show that the mode number affects the accuracy of the dynamic response. A mode number greater than 10 is required to enable the calculated dynamic responses to be independent of the mode number. The dynamic response is also greatly affected by soil properties. The larger the side resistance, the smaller the displacement response and the smaller the refl ected velocity wave crest. The displacement increases as the stress waves propagate along the pile when the pile shaft is free. The incident waves of displacement and velocity responses of the pile are not the same among different points in the circumferential direction on the pile top. However, the arrival time and peak value of the pile tip refl ected waves are almost the same among different points on the pile top. | Ding Xuanming Liu Hanlong Chu Jian Cheng Ke | 2015 | Earthquake Engineering and Engineering Vibration2015，14，2： | 8 |
| 17 | A comprehensive review of ultralow‑weight proppant technology显示文摘Proppant plays a critical role in the exploitation of oil and gas,especially in the development of nonconventional oil and gas resources.Proppants are small spheres that have adequate strength to withstand high closure stresses to keep cracks open;therefore,hydrocarbon fows smoothly into the wellbore.However,traditional proppants are prone to settling in hydraulic fracturing operations,which seriously afects the operation efect.To this end,ultralow-weight proppants have been extensively employed in the petroleum industry.One of the widespread forms of ultralow-weight proppant application in the oil and gas industry is related to light density.Ultralow-weight proppants will provide substantial fow paths with a considerably high propped surface area and remarkably reduce fne generation and scaling.This paper presents a comprehensive review of over 50 papers published in the past several decades on ultralow-weight proppants.The purpose of this study is to provide an overview of the current ultralow-weight proppant development status in raw materials,manufacturing process,performance characteristics,hydrophobic and lipophilic capabilities,and feld application to promote the research of new ultralow-weight proppants.Lastly,this study analyzes the current challenges and emphasizes the development direction of fractured proppants. | Yong-Cun Feng Cheng-Yun Ma Jin-Gen Deng Xiao-Rong Li Ming-Ming Chu Cheng Hui Yu-Yang Luo | 2021 | Petroleum Science2021，18，3： | 7 |
| 18 | Idiopathic airway-centered interstitial fibrosis:report of two cases显示文摘<正> Airway-centered interstitial fibrosis(ACIF),a novelform of diffuse interstitial lung disease (ILD) ofunknown cause,was recently presented.~1 There is no finalconclusion on its property and denomination,and it mightbe a new type of idiopathic interstitial pneumonia(IIP).~1Histopathologically,it was characterized by progressivelobular or small ACIF,and neither similar to any knowncategory of airway disease and ILD,nor similar to knownsubtype of IIP.It showed a poor response tocorticosteroids and poor progrnosis.It has been reportedin Caucasian patients,here,we utilized the termidiopathic airway-centered interstitial fibrosis(IAIF)forthe disease to report 2 Chinese patients,in order toimprove understanding and diagnosis of this disease. | YI Xiang-hua CHU Hai-qing CHENG Xiao-ming LUO Ben-fang LI Hui-ping | 2007 | Chinese Medical Journal2007，，9： | 7 |
| 19 | Relationship of serum vitamin D level on geriatric syndromes and physical performance impairment in elderly hypertensive patients显示文摘ObjectiveTo 与 hypertension.MethodsAccording 在长辈在浆液维生素 D 层次,物理表演缺陷,和衰老老人症候群之中调查关系到维生素 D 层次的集中,有高血压的 143 个老病人的一个总数被分类进维生素 D 缺乏的组(维生素 D ≤20 ng/mL, n = 94 ) 并且维生素 D 适当的组(维生素 D >20 ng/mL, n = 49 ) 。衰老老人症候群和物理性能被使用全面衰老老人评价(CGA ) 估计。在维生素 D 层次,衰老老人症候群和物理性能之中的关联是统计差别在在二个组之间的衰老老人症候群的各种各样的方面被发现的 analyzed.ResultsNo (P >0.05 ) 。当关联分析显示维生素 D 层次与 ADL 有一个积极协会时,得分(r = 0.235, P <0.01 ) 并且有莫尔斯秋天规模 20 的一个否定协会(r =-0.238, P <0.01 ) 。有缺乏的维生素 D 的病人在五次两个都铺平有的更长的时间坐承受测试(5tSTS ) ,(15.765 ±5.593 ) 并且四米的散步测试[7.440 (5.620, 9.200 )] ,在掌握力量测试的一只更弱的有力的握手(28.049 ±9.522 ) ,并且一个更低的 Tinetti 面向表演的活动性评价(Tinetti POMA )[26 (22, 27 )] 并且 Tinetti 面向表演的活动性评价(B-POMA ) 的平衡 subscale 得分[14 (12, 16 )] ,与适当维生素 D 相比水平[(13.275 ±3.692 ) ;5.810 (4.728, 7.325 )] ;( 31.989 ±10.217 ) ;[26.5 (25, 28 )] ;[15 (14, 16 ) ,分别地所有 P <0.05 ] 。而且,逻辑回归的结果显示维生素 D 显著地与 5tSTS 被联系(或 = 1.2, 95% CI = 1.050-1.331, P <0.01 ) , Tinetti POMA (或 = 3.7, 95% CI:1.284-10.830, P <0.05 ) 并且 B-POMA (或 = 0.8, 95% CI:0.643-0.973, P <0.05 ).ConclusionsIn 老高血压的病人,浆液维生素 D 缺乏的水平与物理性能被联系缺陷。然而,没有统计意义在维生素 D 和衰老老人症候群之间被发现。进一步的学习被要求为在维生素 D 和物理性能之间的协会调查可能的机制。 | Xing-Kun ZENG Shan-Shan SHEN Jiao-Jiao CHU Ting HE Lei CHENG Xu-Jiao CHEN | 2016 | Journal of Geriatric Cardiology2016，13，6： | 7 |
| 20 | A Tailored High-Efficiency Sample Pretreatment Method for Simultaneous Quantification of 10 Classes of Known Endogenous Phytohormones显示文摘One of the hottest topics in plant hormone biology is the crosstalk mechanisms,whereby multiple classes of phytohormones interplay with each other through signaling networks.To better understand the roles of hormonal crosstalks in their complex regulatory networks,it is of high significance to investigate the spatial and temporal distributions of multiple-phytohormones simultaneously from one plant tissue sample.In this study,we develop a high-sensitivity and high-throughput method for the simultaneous quantitative analysis of 44 phytohormone compounds,covering currently known 10 major classes of phytohormones(strigolactones,brassinosteroids,gibberellins,auxin,abscisic acid,jasmonic acid,salicylic acid,cytokinins,ethylene,and polypeptide hormones[e.g.,phytosulfokine])from only 100 mg of plant sample.These compounds were grouped and purified separately with a tailored solid-phase extraction procedure based on their physicochemical properties and then analyzed by LC–MS/MS.The recoveries of our method ranged from 49.6%to 99.9%and the matrix effects from 61.8%to 102.5%,indicating that the overall sample pretreatment design resulted in good purification.The limits of quantitation(LOQs)of our method ranged from 0.06 to 1.29 pg/100 mg fresh weight and its precision was less than 13.4%,indicating high sensitivity and good reproducibility of the method.Tests of our method in different plant matrices demonstrated its wide applicability.Collectively,these advantages will make our method helpful in clarifying the crosstalk networks of phytohormones. | Peiyong Xin Qiuhuan Guo Bingbing Li Shujing Cheng Jijun Yan Jinfang Chu | 2020 | Plant Communications2020，1，3： | 7 |
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