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| 1 | Bidding Strategy of a Virtual Power Plant Considering Carbon-electricity Trading显示文摘Virtual power plant(VPP)aggregates large amounts of distributed energy and controllable loads.The comprehensive consideration of carbon emissions and electricity transactions has great significance in improving the VPP operation’s economic efficiency.In this paper,the bidding strategy of the VPP by considering the carbon-electricity integration trading in an auxiliary service(AS)market is studied.First of all,the basic structure and operating features of the VPP are briefly introduced.Then,the bidding strategy model of carbon-electricity integration trading in an auxiliary service market is proposed and the corresponding objective function and the constraint conditions are also analyzed.Furthermore,the GAMS solver is utilized to give the optimal solution of the bidding strategy model.Finally,the effectiveness of the bidding strategy of a VPP based on the consideration of carbon-electricity integration trading is verified through simulation cases. | Dechang Yang Shaowen He Qiuyue Chen Dingqian Li Hrvoje Pandzic | 2019 | CSEE Journal of Power and Energy Systems2019，5，3： | 14 |
| 2 | Expert consensus on the glycemic management of critically ill patients显示文摘Introduction The incidence of hyperglycemia is 40-60%in critically ill patients and is up to 60-80%in those who have undergone car-diac surgery.[1]The results of an epidemiological study in the United States showed that 28.6%of diabetic patients and 9.3%of non-diabetic patients had elevated mean daily glucose on the day of ICU admission.[2]In critically ill patients,elevated blood glucose is primarily the result of stress,and stress-induced hy-perglycemia is an independent risk factor associated with prog-nosis,regardless of a previous diagnosis of diabetes.Nutritional therapy has become an integral treatment option for patients in the ICU,[3,4]though nearly 30%of patients with enteral nu-trition and 44-50%with parenteral nutrition(PN)experience elevated glucose.[5,6]Intensive insulin therapy(IIT)is an impor-tant treatment for controlling hyperglycemia in critically ill pa-tients,but it also carries a corresponding risk of hypoglycemia. | Zhixiong Wu Jiao Liu Dong Zhang Kai Kang Xiangrong Zuo Qianghong Xu Aijun Pan Wei Fang Fen Liu You Shang Haiyan Yin Juntao Hu Jinglun Liu Jiangquan Fu Wei Zhang Yuan Zong Min Shao Feng Zhao Mei Meng Yanfei Mao Yingchuan Li Dechang Chen | 2022 | Journal of Intensive Medicine2022，2，3： | 9 |
| 3 | Comparison of Charlson's weighted index of comorbidities with the chronic health score for the prediction of mortality in septic patients显示文摘 | Cui Yunliang Wang Tao Bao Jun Tian Zhaotao Lin Zhaofen Chen Dechang | 2014 | Chinese Medical Journal2014，，14： | 4 |
| 4 | Lipopolysaccharide induced intestinal epithelial injury:a novel organoids-based model for sepsis in vitro显示文摘Background: Advances in organoid culture technology have provided a greater understanding of disease pathogenesis, which has been rarely studied in sepsis before. We aim to establish a suitable organoids-based intestinal injury model for sepsis.Methods: Stable passaged organoids were constructed and pre-treated with lipopolysaccharide (LPS) to mimic sepsis-induced intestinal injury. The LPS-induced sepsis model was used as a reference. We used quantitative real-time polymerase chain reaction to evaluate the RNA levels of inflammatory factors and antimicrobial peptides. Enzyme-linked immunosorbent assay was used to evaluate the protein levels, hematoxylin and eosin staining was used to evaluate the pathology of the small intestine of mice, and immunohistochemistry and immunofluorescence were used to evaluate the intestinal epithelial barrier function. Perkin Elmer OperettaTM was used to obtain high-resolution images of three-dimensional organoids.Results: An LPS concentration >150 μg/mL after 24 h was identified to cause organoid growth restriction. The fluorescence intensity of zonula occludens-1 and occludins at LPS concentrations >100 μg/mL decreased significantly after 24 h. After LPS stimulation for 8 h, the RNA expression levels of interleukin (IL)-1α, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, IL-6, and regenerating islet-derived protein 3 alpha, beta, and gamma increased. These results resembled those of intestinal epithelial layer alterations in a mouse sepsis model. For IL-10, the RNA expression level increased only when the LPS level >200 μg/mL for 24 h.Conclusions: This study provides the primary intestinalin vitro model to study the effects of LPS-induced intestinal injury resembling sepsis. This model provides a platform for immune associated mechanism exploration and effective drug screening. | Sisi Huang Sheng Zhang Limin Chen Xiaojun Pan Zhenliang Wen Yizhu Chen Lidi Zhang Jiao Liu Dechang Chen | 2022 | Chinese Medical Journal2022，135，18： | 3 |
| 5 | Improved insensitive to input parameters trajectory clustering algorithm显示文摘The existing trajectory clustering(TRACLUS) is sensitive to the input parameters ε and MinLns. The parameter value is changed a little, but cluster results are entirely different. Aiming at this vulnerability, a shielding parameters sensitivity trajectory cluster(SPSTC) algorithm is proposed which is insensitive to the input parameters. Firstly, some definitions about the core distance and reachable distance of line segment are presented, and then the algorithm generates cluster sorting according to the core distance and reachable distance. Secondly, the reachable plots of line segment sets are constructed according to the cluster sorting and reachable distance. Thirdly, a parameterized sequence is extracted according to the reachable plot, and then the final trajectory cluster based on the parameterized sequence is acquired. The parameterized sequence represents the inner cluster structure of trajectory data. Experiments on real data sets and test data sets show that the SPSTC algorithm effectively reduces the sensitivity to the input parameters, meanwhile it can obtain the better quality of the trajectory cluster. | Jiashun Chen Dechang Pi | 2013 | Journal of Systems Engineering and Electronics2013，24，5： | 3 |
| 6 | Target serum concentration of vancomycin may be reached earlier with a loading dose显示文摘Background:Vancomycin treatment failure against vancomycin-susceptible gram-positive cocci is not rare in the intensive care unit(ICU).One of the reasons for this is the substandard drug trough concentration.We aimed to examine the hypothesis that the target serum concentration could be reached earlier with a loading dose of vancomycin.Methods:This retrospective cohort study was conducted at our ICU between June 2018 and June 2020 and involved patients who were suspected of having,or confirmed to have,gram-positive cocci infection and treated with vancomycin.One group of the patients was administered a loading dose of vancomycin(loading group)and compared with the group that did not receive a loading dose(control group).The baseline characteristics,vancomycin serum concentrations,and clinical outcomes were collected and analyzed.Results:Fifty-five patients were finally included,of which 29 received a loading dose of vancomycin.The serum concentration of vancomycin before the second dose was significantly higher for the loading group than for the control group(10.3±6.1 mg/Lvs.5.7±4.4 mg/L,P=0.002).The results for both groups were similar before the fifth dose(12.4±7.3 mg/Lvs.10.3±6.3 mg/L in the loading and the control groups,respectively;P=0.251).The 28-day mortality was lower for the loading group than for the control group(6.7%vs.34.6%in the loading and control groups,respectively;P=0.026).No significant differences were observed in serum creatinine(Cr)concentrations of the two groups.Conclusion:With the loading dose of vancomycin,the target serum concentration of vancomycin may be reached earlier without increasing the risk of acute kidney injury. | Yanxia Huang Le He Yunxin Deng Renjing Zhang Mei Meng Jiao Liu Dechang Chen | 2022 | Chinese Medical Journal2022，，3： | 2 |
| 7 | Effect of surfactant protein A on lipopolysaccharide-induced tumor necrosis factor-α expression in human proximal tubular epithelial cells显示文摘 | Liu Jiao Liu Zhiyong Feng Lizhi Ding Guohua Chen Dechang Zhou Qingshan | 2014 | Chinese Medical Journal2014，，2： | 2 |
| 8 | Microstructural evolution of h-BN matrix composite ceramics with La-Al-Si-O glass phase during hot-pressed sintering显示文摘BN/La-Al-Si-O composite ceramics were fabricated by hot-pressed sintering using hexagonal boron nitride(h-BN),lanthanum oxide(La_(2)O_(3)),aluminia(Al_(2)O_(3)),and amorphous silica(SiO_(2))as the raw materials.The effects of sintering temperature on microstructural evolution,bulk density,apparent porosity,and mechanical properties of the h-BN composite ceramics were investigated.The results indicated that La-Al-Si-O liquid phase was formed during sintering process,which provided an environment for the growth of h-BN grains.With increasing sintering temperature,the cristobalite phase precipitation and h-BN grain growth occurred at the same time,which had a significant influence on the densification and mechanical properties of h-BN composite ceramics.The best mechanical properties of BN/La-Al-Si-O composite ceramics were obtained under the sintering temperature of 1700℃.The elastic modulus,flexural strength,and fracture toughness were 80.5 GPa,266.4 MPa,and 3.25 MPa·m^(1/2),respectively. | Baofu QIU Xiaoming DUAN Zhuo ZHANG Chen ZHAO Bo NIU Peigang HE Delong CAI Lei CHEN Zhihua YANG Yujin WANG Dechang JIA Yu ZHOU | 2021 | Journal of Advanced Ceramics2021，10，3： | 2 |
| 9 | Advanced lanthanide doped upconversion nanomaterials for lasing emission显示文摘Microlasers are narrow-band and coherent light from small cavities,which have been widely applied in biomedicine,optical interconnection,integration devices,etc.Lanthanide doped upconversion materials are potential gain media for microlasers from near infrared(NIR)to visible and UV regimes due to their multi ladder-like metastable energy levels and superior optical frequency conversion capability.The optical feedback from photon scattering of the porous upconversion nanoparticles clusters has been reported to produce upconversion random lasers.The light bouncing back and forth between two reflective surfaces or internal surface has been utilized to achieve modulated upconversion lasing emission.In addition,photon lattices and plasmonic cavities with enhanced electromagnetic fields can amplify the upconversion process within the sub-diffraction volumes and produce highly efficient upconverting lasers.In this review,the recent advances on using lanthanide doped upconversion materials for random,whispering gallery mode(WGM)/Fabry-Perot(FP)cavity and photon lattice/plasmonic cavity modulated upconversion microlasers are overviewed.Current challenges and future directions of the upconverting lasers are also discussed. | Yunfei Shang Tong Chen Tianhui Ma Shuwei Hao Weiqiang Lv Dechang Jia Chunhui Yang | 2022 | Journal of Rare Earths2022，40，5： | 2 |
| 10 | Induction of the Heat Shock Response In Vivo Inhibits NF-κB Activity and Protects Murine Liver from Endotoxemia-Induced Injury显示文摘 | Dechang Chen Jiaqi Pan Bin Du Dongxu Sun | 2005 | Journal of Clinical Immunology2005，，5： | 1 |
| 11 | Restriction of thirdgeneration cephalosporin use decreases infection-related mortality显示文摘 | DU Bin CHEN Dechang LIU Dawei | 2003 | Critical Care Medicine2003，31，4： | 1 |
| 12 | Clinical review: Critical care medicine in mainland China 显示文摘 | Bin Du XiuMing Xi Dechang Chen | 2010 | Crit Care2010，14，： | 1 |
| 13 | Effect of Wuda granule on gastrointestinal function recovery after laparoscopic intestinal resection:a randomized–controlled trial显示文摘Background Previous studies have suggested that the Wuda granule(WDG)could promote the recovery of gastrointestinal(GI)function after gynecologic abdominal surgery.This trial aimed to investigate the efficacy and safety of WDG in the rapid recovery of GI function in patients after laparoscopic intestinal resection in the setting of enhanced recovery after surgery(ERAS)-based perioperative care.Methods We performed a randomized,double-blind,placebo-controlled pilot trial.Thirty patients who met the inclusion criteria were randomly assigned to either the WDG group or the placebo group in a 1:1 ratio.The patients received WDG or placebo twice a day in addition to ERAS-based perioperative care,starting on post-operative Day 1 until Day 3.The primary outcomes were time to first bowel movement and time to first tolerance of solid food.The secondary outcomes were time to first flatus,length of hospital stay(LOS),and post-operative ileus-related morbidity.Adverse events were also recorded.Results There were no statistically significant differences in baseline characteristics between the two groups.The median time to first bowel movement was significantly decreased in the WDG group compared with the control group(27.6 vs 50.1 h;P<0.001),but the median times to first flatus(22.9 vs 25.1 h;P>0.05)and LOS(5.0 vs 5.0 days;P>0.05)were not statistically different.The occurrence rates of post-operative nausea,vomiting,abdominal distension,and abdominal pain were similar in the two groups.No adverse events occurred in any patients.Conclusions The addition of WDG to ERAS post-operative care after laparoscopic intestinal resection can safely promote the rapid recovery of GI function. | Haiping Zeng Wei Wang Lixing Cao Yuyan Wu Wenwei Ouyang Dechang Diao Jin Wan Qicheng Chen Zhiqiang Chen | 2022 | Gastroenterology Report2022，10，1： | 1 |
| 14 | Activating transcription factor 4 protects mice against sepsis-induced intestinal injury by regulating gut-resident macrophages differentiation显示文摘Background: Gut-resident macrophages (gMacs) supplemented by monocytes-to-gMacs differentiation play a critical role in maintaining intestinal homeostasis. Activating transcription factor 4 (ATF4) is involved in immune cell differentiation. We therefore set out to investigate the role of ATF4-regulated monocytes-to-gMacs differentiation in sepsis-induced intestinal injury.Methods: Sepsis was induced in C57BL/6 wild type (WT) mice andAtf4-knockdown (Atf4+/-) mice by cecal ligation and puncture or administration of lipopolysaccharide (LPS). Colon, peripheral blood mononuclear cells, sera, lung, liver, and mesenteric lymph nodes were collected for flow cytometry, hematoxylin and eosin staining, immunohistochemistry, quantitative reverse transcription polymerase chain reaction, and enzyme-linked immunosorbent assay, respectively.Results: CD64, CD11b, Ly6C, major histocompatibility complex-II (MHC-II), CX3CR1, Ly6G, and SSC were identified as optimal primary markers for detecting the process of monocytes-to-gMacs differentiation in the colon of WT mice. Monocytes-to-gMacs differentiation was impaired in the colon during sepsis and was associated with decreased expression of ATF4 in P1 (Ly6Chi monocytes), the precursor cells of gMacs.Atf4 knockdown exacerbated the impairment of monocytes-to-gMacs differentiation in response to LPS, resulting in a significant reduction of gMacs in the colon. Furthermore, compared with WT mice,Atf4+/- mice exhibited higher pathology scores, increased expression of inflammatory factor genes (TNF-α, IL-1β), suppressed expression of CD31 and vascular endothelial-cadherin in the colon, and increased translocation of intestinal bacteria to lymph nodes and lungs following exposure to LPS. However, the aggravation of sepsis-induced intestinal injury resulting fromAtf4 knockdown was not caused by the enhanced inflammatory effect of Ly6Chi monocytes and gMacs.Conclusion: ATF4, as a novel regulator of monocytes-to-gMacs differentiation, plays a critical role in protecting mice against sepsis-induced intestinal injury, suggesting that ATF4 might be a potential therapeutic target for sepsis treatment. | Zhenliang Wen Xi Xiong Dechang Chen Lujing Shao Xiaomeng Tang Xuan Shen Sheng Zhang Sisi Huang Lidi Zhang Yizhu Chen Yucai Zhang Chunxia Wang Jiao Liu | 2022 | Chinese Medical Journal2022，135，21： | 1 |
| 15 | Experimental Investigation on Oil Shale Circulating Fluidized Bed Boiler 显示文摘 | Jiang Xiumin Liu Dechang Chen Hanping | 2001 | Oil Shale2001，18，1： | 1 |
| 16 | Restriction of thirdgeneration cephalosporin use decreases infection-related mortality显示文摘 | Bin Du Dechang Chen Dawei Liu | 2003 | Crit Care Med2003，32，4： | 1 |
| 17 | Artificial Immune K-means Grid-density Clustering Algorithm for REAL-time Monitoring and Analysis of Urban Traffic显示文摘 | Chen Chuanming Pi Dechang Fang Zhuoran | 2013 | Electronics Letters2013，49，20： | 1 |
| 18 | A visibly transparent radiative cooling film with self-cleaning function produced by solution processing显示文摘Daylighting structures,including solar cells and building windows,utilize sunlight whilst suffering from undesired solar heat and outdoor dust contamination.A radiative cooling system that is transparent to sunlight and has a superhydrophobic surface would cool and clean the daylighting structures in a sustainable manner.However,the majority of the current daytime radiative cooling systems were designed to fully reflect the incident sunlight to maximize the cooling power.In this work,we optimized both the sunlight transmission and infrared thermal irradiation by modeling the size-dependent scattering and absorption of light by SiO_(2)spheres embedded in a polymer matrix,we found that the use of nanospheres(20 nm)enabled both high sunlight transmittance(>90%)and infrared emissivity(-0.85).This theoretical prediction was confirmed by experimental measurements of a solution-processed nanocomposite film.When coated on a solar cell,the as-prepared film not only preserved the power conversion efficiency of the cell(14.71%,uncoated cell has an efficiency of 14.79%)but also radiatively cooled the cell by up to 5℃under direct sunlight.This reduction of the operating temperature of the solar cell further enhanced its electrical power output,evidenced by an increase in the equilibrium temperature of the LED load by about 14℃.The nanoscale textured surface formed by the nanospheres further led to superhydrophobicity and thus excellent self-cleaning performance(efficient removal of dust by wind and/or water droplets). | Guoliang Chen Yaming Wang Jun Qiu Jianyun Cao Yongchun Zou Shuqi Wang Jiahu Ouyang Dechang Jia Yu Zhou | 2021 | Journal of Materials Science & Technology2021，，31： | 0 |
| 19 | Cooperative spectrum sharing of multiple primary users and multiple secondary users显示文摘 | Hang Liu Sha Hua Xuejun Zhuo Dechang Chen Xiuzhen Cheng | 2016 | Digital Communications and Networks2016，2，4： | 0 |
| 20 | Expert consensus on blood pressure management in critically ill patients显示文摘Introduction For critically ill patients with unstable hemodynamics,goal‑directed therapy for arterial blood pressure is needed with continuous daily bedside monitoring.The prevalence of hypertension in Chinese adults is 25.2%,of which 1–2%of patients may experience a hypertensive emergency,with a mortality rate of 6.9%in the acute phase.The mortality and readmission rates within 90 days of onset are as high as 11%.[1]Furthermore,the mortality rate for patients who experience hypertensive emergencies can reach 50%within 12 months of the incident.[2]The incidence of perioperative hypertension in patients undergoing cardiac surgery is approximately 50%,with this figure dropping to 25%for non-cardiac surgery.Surgery may increase the incidence of perioperative cardio-cerebrovascular adverse events by 3–5%.[3] | Yuetian Yu Ye Gong Bo Hu Bin Ouyang Aijun Pan Jinglun Liu Fen Liu Xiu-Ling Shang Xiang-Hong Yang Guowei Tu Changsong Wang Shaolin Ma Wei Fang Ling Liu Jiao Liu Dechang Chen | 2023 | Journal of Intensive Medicine2023，3，3： | 0 |
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