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| 1 | High-resolution remote sensing mapping of global land water显示文摘Land water, one of the important components of land cover, is the indispensable and important basic information for climate change studies, ecological environment assessment, macro-control analysis, etc. This article describes the overall study on land water in the program of global land cover remote sensing mapping. Through collection and processing of Landsat TM/ETM+, China's HJ-1 satellite image, etc., the program achieves an effective overlay of global multi-spectral image of 30 m resolution for two base years, namely, 2000 and 2010, with the image rectification accuracy meeting the requirements of 1:200000 mapping and the error in registration of images for the two periods being controlled within 1 pixel. The indexes were designed and selected reasonably based on spectral features and geometric shapes of water on the scale of 30 m resolution, the water information was extracted in an elaborate way by combining a simple and easy operation through pixel-based classification method with a comprehensive utilization of various rules and knowledge through the object-oriented classification method, and finally the classification results were further optimized and improved by the human-computer interaction, thus realizing high-resolution remote sensing mapping of global water. The completed global land water data results, including Global Land 30-water 2000 and Global Land 30-water 2010, are the classification results featuring the highest resolution on a global scale, and the overall accuracy of self-assessment is 96%. These data are the important basic data for developing relevant studies, such as analyzing spatial distribution pattern of global land water, revealing regional difference, studying space-time fluctuation law, and diagnosing health of ecological environment. | LIAO AnPing CHEN LiJun CHEN Jun HE ChaoYing CAO Xin CHEN Jin PENG Shu SUN FangDi GONG Peng | 2014 | Science China Earth Sciences2014，57，10： | 22 |
| 2 | Monitoring mine collapse by D-InSAR显示文摘For harmful ground collapse and its special deformation characteristics,which causes SAR images to lose coherence,InSAR technology cannot be applied in monitoring surface collapse in mining areas.We took the Shenmu mining area in northern Shaanxi province as an example to study subsidence in mining areas and proposed an interpolated multi-view processing method.The results show that this method can improve the detectable deformation gradient to a certain extent and can become a good reference value for monitoring large scale gradient deformation.We also analyzed the rules for temporal decorrelation in mining. | YANG Chengsheng ZHANG Qin ZHAO Chaoying JI Lingyun ZHU Wu | 2010 | Mining Science and Technology2010，20，5： | 21 |
| 3 | Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘 | Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang | 2012 | Cellular & Molecular Immunology2012，9，3： | 18 |
| 4 | Microstructure evolution of AZ91 alloy processed by a combination method of equal channel angular pressing and rolling显示文摘In the present work,AZ91 alloy was successfully processed by equal channel angular pressing(ECAP)for up to 16 passes and rolling(R)for multiple passes with a total reduction of 75%in addition to a combination method with ECAP plus rolling(ECAP+R).The effects of various processes(ECAP,R and ECAP+R)on microstructure evolution were analyzed and the influence of ECAP process on the rolling performance was examined.The result shows that ECAP contributed to a homogenous grain structure and formed a texture with higher Schmidt factors that was easy for rolling.A plate with smoother surface and reduced edge cracks was observed in the ECAP+R process than in the single R process.Although the microstructure of the alloy was similar after ECAP+R and R process,the sample of ECAP+R was more refined and had stronger second phase precipitation than the sample of R,which resulted in better rolling characteristics,along with the external surfaces. | Qiong Xu Aibin Ma Yuhua Li Jiapeng Sun Yuchun Yuan Jinghua Jiang Chaoying Ni | 2020 | Journal of Magnesium and Alloys2020，8，1： | 10 |
| 5 | Preliminary analysis of spatiotemporal pattern of global land surface water显示文摘Land surface water(LSW) is one of the most important resources for human survival and development, and it is also a main component of global water recycling. A full understanding of the spatial distribution of land surface water and a continuous measuring of its dynamics can support to diagnose the global ecosystem and environment. Based on the Global Land 30-water 2000 and Global Land 30-water 2010 products, this research analyzed the spatial distribution pattern and temporal fluctuation of land surface water under scale-levels of global, latitude and longitude, continents, and climate zones. The Global Land 30-water products were corrected the temporal inconsistency of original remotely sensed data using MODIS time-series data, and then calculated the indices such as water area, water ration and coefficient of spatial variation for further analysis. Results show that total water area of land surface is about 3.68 million km2(2010), and occupies 2.73% of land area. The spatial distribution of land surface water is extremely uneven and is gathered mainly in mid- to high-latitude area of the Northern Hemisphere and tropic area. The comparison of water ratio between 2000 and 2010 indicates the overall fluctuation is small but spatially differentiated. The Global Land 30-water products and the statistics provided the fundamental information for analyzing the spatial distribution pattern and temporal fluctuation of land surface water and diagnosing the global ecosystem and environment. | CAO Xin CHEN Jun CHEN LiJun LIAO AnPing SUN FangDi LI Yang LI Lei LIN ZhongHui PANG ZhiGuo CHEN Jin HE ChaoYing PENG Shu | 2014 | Science China Earth Sciences2014，57，10： | 8 |
| 6 | Capecitabine maintenance therapy for XT chemotherapy-sensitive patients with metastatic triple-negative breast cancer显示文摘Objective: To investigate the efficacy and safety of capecitabine maintenance therapy(MT) after initial capecitabine plus docetaxel(XT) chemotherapy in patients with metastatic triple-negative breast cancer(m TNBC).Methods: Fifty-five m TNBC patients treated with XT chemotherapy between May 2007 and June 2013 were retrospectively analyzed. When initial disease control was achieved by the combination chemotherapy, capecitabine was continued for 32 patients(MT), while 23 patients remained without any treatment(nonMT). We compared progression-free survival(PFS) and safety of both groups.Results: The median PFS of 55 patients was 8.1 months, overall median PFS time of 32 patients in the capecitabine MT group and 23 in the non-MT group was 10.1 vs. 6.7 months(P=0.032), respectively. When compared PFS time of maintenance treatment, single-agent capecitabine prolonged PFS by 7.1 months, for non-MT patients, the PFS without any treatment was 3.1 months, and this between-group difference was statistically significant(P=0.003). Adverse events, including of hematologic toxicity, gastrointestinal toxicities, hand-foot syndrome and abnormal liver function were not significantly different between two groups.Conclusions: After initial disease control was achieved with the XT combination chemotherapy, capecitabine MT can significantly prolong PFS time with a favorable safety profile in m TNBC patients. | Xu Liang Lijun Di Guohong Song Ying Yan Chaoying Wang Hanfang Jiang Huiping Li | 2014 | Chinese Journal of Cancer Research2014，26，5： | 8 |
| 7 | Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia显示文摘Nitric oxide(NO) is an important molecule for vasomotor tone, and elevated NO signaling was previously hypothesized as a unique and adaptive physiological change in highland Tibetans. However, there has been lack of NO data from Tibetans living at low altitude and lowlander immigrants living at high altitude, which is crucial to test this hypothesis. Here, through cross-altitude(1990–5018 m) and cross-population(Tibetans and Han Chinese) analyses of serum NO metabolites(NOx) of 2086 individuals, we demonstrate that although Tibetans have a higher serum NOx level compared to lowlanders, Han Chinese immigrants living at high altitude show an even higher level than Tibetans. Consequently, our data contradict the previous proposal of increased NO signaling as the unique adaptive strategy in Tibetans.Instead, Tibetans have a relatively lower circulating NOx level at high altitude. This observation is further supported by data from the hypoxic experiments using human umbilical vein endothelial cells and gene knockout mice. No difference is detected between Tibetans and Han Chinese for endothelial nitric oxide synthase(e NOS), the key enzyme for circulating NO synthesis, suggesting that e NOS itself is unlikely to be the cause. We show that other NO synthesis-related genes(e.g. GCH1) carry Tibetan-enriched mutations significantly associated with the level of circulating NOx in Tibetans. Furthermore, gene network analysis revealed that the downregulation and upregulation of NOx is possibly achieved through distinct pathways.Collectively, our findings provide novel insights into the physiological and genetic mechanisms of the evolutionary adaptation of Tibetans to high-altitude hypoxia. | Yaoxi He Xuebin Qi Ouzhuluobu Shiming Liu Jun Li Hui Zhang Baimakangzhuo Caijuan Bai Wangshan Zheng Yongbo Guo Duojizhuoma Baimayangji Dejiquzong Bianba Gonggalanzi Yongyue Pan Qula Kangmin Cirenyangji Wei Guo Yangla Yi Peng Xiaoming Zhang Kun Xiang Zhaohui Yang Liangbang Wang Gengdeng Yanfeng Zhang Tianyi Wu Bing Su Chaoying Cui | 2018 | National Science Review2018，5，4： | 7 |
| 8 | Transcriptome analysis reveals key differentially expressed genes involved in wheat grain development显示文摘Wheat seed development is an important physiological process of seed maturation and directly affects wheat yield and quality. In this study, we performed dynamic transcriptome microarray analysis of an elite Chinese bread wheat cultivar(Jimai 20) during grain development using the Gene Chip Wheat Genome Array. Grain morphology and scanning electron microscope observations showed that the period of 11–15 days post-anthesis(DPA) was a key stage for the synthesis and accumulation of seed starch. Genome-wide transcriptional profiling and significance analysis of microarrays revealed that the period from 11 to 15 DPA was more important than the 15–20 DPA stage for the synthesis and accumulation of nutritive reserves.Series test of cluster analysis of differential genes revealed five statistically significant gene expression profiles. Gene ontology annotation and enrichment analysis gave further information about differentially expressed genes, and Map Man analysis revealed expression changes within functional groups during seed development. Metabolic pathway network analysis showed that major and minor metabolic pathways regulate one another to ensure regular seed development and nutritive reserve accumulation. We performed gene co-expression network analysis to identify genes that play vital roles in seed development and identified several key genes involved in important metabolic pathways. The transcriptional expression of eight key genes involved in starch and protein synthesis and stress defense was further validated by q RT-PCR. Our results provide new insight into the molecular mechanisms of wheat seed development and the determinants of yield and quality. | Yonglong Yu Dong Zhu Chaoying Ma Hui Cao Yaping Wang Yanhao Xu Wenying Zhang Yueming Yan | 2016 | The Crop Journal2016，4，2： | 6 |
| 9 | Structural vibration passive control and economic analysis of a high-rise building in Beijing显示文摘Performance analysis of the Pangu Plaza under earthquake and wind loads is described in this paper.The plaza is a 39-story steel high-rise building,191 m high,located in Beijing close to the 2008 Olympic main stadium.It has both fluid viscous dampers(FVDs) and buckling restrained braces or unbonded brace(BRB or UBB) installed.A repeated iteration procedure in its design and analysis was adopted for optimization.Results from the seismic response analysis in the horizontal and vertical directions show that the FVDs are highly effective in reducing the response of both the main structure and the secondary system.A comparative analysis of structural seismic performance and economic impact was conducted using traditional methods,i.e.,increased size of steel columns and beams and/or use of an increased number of seismic braces versus using FVD.Both the structural response and economic analysis show that using FVD to absorb seismic energy not only satisfi es the Chinese seismic design code for a 'rare' earthquake,but is also the most economical way to improve seismic performance both for one-time direct investment and long term maintenance. | Chen Yongqi Cao Tiezhu Ma Liangzhe Luo Chaoying | 2009 | Earthquake Engineering and Engineering Vibration2009，8，4： | 6 |
| 10 | Evaluation Model of Design for Operation and Architecture of Hierarchical Virtual Simulation for Flight Vehicle Design显示文摘In order to take requirements for commercial operations or military missions into better consideration in new flight vehicle design, a tri-hierarchical task classification model of 'design for operation' is proposed, which takes basic man-object interaction task, complex collaborative operation and large-scale joint operation into account. The corresponding general architecture of evaluation criteria is also depicted. Then a virtual simulation-based approach to implement the evaluations at three hierarchy levels is mainly analyzed with a detailed example, which validates the feasibility and effectiveness of evaluation architecture. Finally, extending the virtual simulation architecture from design to operation training is discussed. | LIU Hua TIAN Yongliang ZHANG Chaoying YIN Jiao SUN Yijie | 2012 | Chinese Journal of Aeronautics2012，25，2： | 6 |
| 11 | A semiempirical algorithm for SAR wave height retrieval and its validation using Envisat ASAR wave mode data显示文摘Many synthetic aperture radar(SAR) wave height retrieval algorithms have been developed.However,the wave height retrievals from most existing methods either depend on other input as the first guess or are restricted to the long wave regime.A semiempirical algorithm is presented,which has the objective to estimate the wave height from SAR imagery without any prior knowledge.The proposed novel algorithm was developed based on the theoretical SAR ocean wave imaging mechanism and the empirical relation between two types of wave period.The dependency of the proposed model on radar incident and wave direction was analyzed.For Envisat advanced synthetic aperture radar(ASAR) wave mode data,the model can be reduced to the simple form with two input parameters,i.e.,the cutoff wavelength and peak wavelength of ocean wave,which can be retrieved from SAR imagery without any prior knowledge of wind or wave.Using Envisat ASAR wave mode data and the collocated buoy measurements from NDBC,the semiempirical algorithm is validated and compared with the Envisat ASAR level 2 products.The root-mean-square-error(RMSE) and scatter index(SI) in respect to the in situ measurements are 0.52 m and 19% respectively.Validation results indicate that,for Envisat ASAR wave mode data,the proposed method works well. | WANG He ZHU Jianhua YANG Jingsong SHI Chaoying | 2012 | Acta Oceanologica Sinica2012，31，3： | 6 |
| 12 | Research on an Mg–Zn alloy as a degradable biomaterial显示文摘 | Shaoxiang Zhang Xiaonong Zhang Changli Zhao Jianan Li Yang Song Chaoying Xie Hairong Tao Yan Zhang Yaohua He Yao Jiang Yujun Bian | 2009 | Acta Biomaterialia2009，，2： | 5 |
| 13 | Evaluation of a laying-hen tracking algorithm based on a hybrid support vector machine显示文摘Background: Behavior is an important indicator reflecting the welfare of animals. Manual analysis of video is the most commonly used method to study animal behavior. However, this approach is tedious and depends on a subjective judgment of the analysts. There is an urgent need for automatic identification of individual animals and automatic tracking is a fundamental part of the solution to this problem.Results: In this study, an algorithm based on a Hybrid Support Vector Machine(HSVM) was developed for the automated tracking of individual laying hens in a layer group. More than 500 h of video was conducted with laying hens raised under a floor system by using an experimental platform. The experimental results demonstrated that the HSVM tracker outperformed the Frag(fragment-based tracking method), the TLD(Tracking-Learning-Detection),the PLS(object tracking via partial least squares analysis), the Mean Shift Algorithm, and the Particle Filter Algorithm based on their overlap rate and the average overlap rate.Conclusions: The experimental results indicate that the HSVM tracker achieved better robustness and state-of-theart performance in its ability to track individual laying hens than the other algorithms tested. It has potential for use in monitoring animal behavior under practical rearing conditions. | Cheng Wang Hongqian Chen Xuebin Zhang Chaoying Meng | 2017 | Journal of Animal Science and Biotechnology2017，8，1： | 5 |
| 14 | De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation显示文摘Structural variants(SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-quality Tibetan genome(ZF1), with a contig N50 length of 24.57 mega-base pairs(Mb) and a scaffold N50 length of 58.80 Mb. The ZF1 assembly filled 80 remaining N-gaps(0.25 Mb in total length) in the reference human genome(GRCh38). Markedly, we detected17 900 SVs, among which the ZF1-specific SVs are enriched in GTPase activity that is required for activation of the hypoxic pathway. Further population analysis uncovered a 163-bp intronic deletion in the MKL1 gene showing large divergence between highland Tibetans and lowland Han Chinese. This deletion is significantly associated with lower systolic pulmonary arterial pressure, one of the key adaptive physiological traits in Tibetans. Moreover, with the use of the high-quality de novo assembly, we observed a much higher rate of genome-wide archaic hominid(Altai Neanderthal and Denisovan) shared non-reference sequences in ZF1(1.32%–1.53%) compared to other East Asian genomes(0.70%–0.98%),reflecting a unique genomic composition of Tibetans. One such archaic hominid shared sequence-a662-bp intronic insertion in the SCUBE2 gene-is enriched and associated with better lung function(the FEV1/FVC ratio) in Tibetans. Collectively, we generated the first high-resolution Tibetan reference genome, and the identified SVs may serve as valuable resources for future evolutionary and medical studies. | Ouzhuluobu Yaoxi He Haiyi Lou Chaoying Cui Lian Deng Yang Gao Wangshan Zheng Yongbo Guo Xiaoji Wang Zhilin Ning Jun Li Bin Li Caijuan Bai Baimakangzhuo Gonggalanzi Dejiquzong Bianba Duojizhuoma Shiming Liu Tianyi Wu Shuhua Xu Xuebin Qi Bing Su | 2020 | National Science Review2020，7，2： | 4 |
| 15 | Adsorption of phenol from aqueous solution by a hierarchical micro-nano porous carbon material显示文摘A hierarchical micro-nano porous carbon material (MNC) was prepared using expanded graphite (EG), sucrose, and phosphoric acid as raw materials, followed by sucrose-phosphoric acid solution impregnation, solidification, carbonization and activation. Nitrogen adsorption and mercury porosimetry show that mixed nanopores and micropores coexist in MNC with a high specific surface area of 1978 m2·g-1 and a total pore volume of 0.99 cm3·g-1. In addition, the MNC is found to consist of EG and activated carbon with the latter deposited on the interior and the exterior surfaces of the EG pores. The thickness of the activated carbon layer is calculated to be about one hundred nanometers and is further confirmed by scanning electron microscope (SEM) and transmission election microscope (TEM). A maximum static phenol adsorption of 241.2 mg·g-1 was obtained by using MNC, slightly higher than that of 220.4 mg·g-1 by using commercial activated carbon (CAC). The phenol adsorption kinetics were investigated and the data fitted well to a pseudo-second-order model. Also, an intra-particle diffusion mechanism was proposed. Furthermore, it is found that the dynamic adsorption capacity of MNC is nearly three times that of CAC. The results suggest that the MNC is a more efficient adsorbent than CAC for the removal of phenol from aqueous solution. | Liu Chengbao Chen Zhigang Ni Chaoying Chen Feng Gu Cheng Cao Yu Wu Zhengying Li Ping | 2012 | Rare Metals2012，31，6： | 4 |
| 16 | La1-xCexMnO3/attapulgite nanocomposites as catalysts for NO reduction with NH3 at low temperature显示文摘 | Xiazhang Li YU Yin Chao Yao Shixiang Zuo Xiaowang Lu Shiping Luo Chaoying Ni | 2016 | Particuology2016，14，3： | 4 |
| 17 | 复合钙钛矿太阳能电池电荷传输层材料研究进展显示文摘有机无机复合钙钛矿太阳能电池因具有适合的载流子扩散长度而成为备受关注的有望获得高效率的光伏器件。复合钙钛矿材料本身不含贵金属元素,可以采用液相法或物理气相法低温制备,成本低廉,但目前应用最多的电子传输层材料TiO2需400~500℃煅烧,与柔性基底及低温制备技术适应性差;空穴传输层材料SpiroOMeTAD合成工艺复杂,价格高昂,限制了复合钙钛矿太阳能电池的开发应用。开发和研究导电性好、成本低、稳定性好的电子和空穴传输层材料是复合钙钛矿太阳能电池研究中的一个非常重要的方面。综述了复合钙钛矿太阳能电池中电荷传输层材料的研究进展及发展方向。电子传输层材料方面通过对TiO2的改性以及与石墨烯的复合,采用ZnO、石墨烯或PCBM作为电子传输层材料,以与柔性基底及低温制备技术相适应。空穴传输层材料方面,采用其它低成本、导电性高的有机p型半导体替代spiro-OMeTAD;采用无机空穴传输层材料以避免有机空穴传输层材料的老化问题,提高电池的长期稳定性;利用复合钙钛矿材料兼作吸收层与空穴传输层,制备无空穴传输层材料结构电池以降低成本,提高稳定性。 | 陈建清 杨东辉 江静华 马爱斌 宋丹 Chaoying Ni Michael Z Hu | 2015 | 材料导报2015，29，5： | 4 |
| 18 | Dab2 attenuates brain injury in APP/PS1 mice via targeting transforming growth factor-beta/SMAD signaling显示文摘Transforming growth factor-beta(TGF-β)type II receptor(TβRII)levels are extremely low in the brain tissue of patients with Alzheimer’s disease.This receptor inhibits TGF-β1/SMAD signaling and thereby aggravates amyolid-beta deposition and neuronal injury.Dab2,a specific adapter protein,protects TβRII from degradation and ensures the effective conduction of TGF-β1/SMAD signaling.In this study,we used an adenoviral vector to overexpress the Dab2 gene in the mouse hippocampus and investigated the regulatory effect of Dab2 protein on TGF-β1/SMAD signaling in a mouse model of Alzheimer’s disease,and the potential neuroprotective effect.The results showed that the TβRII level was lower in APP/PS1 mouse hippocampus than in normal mouse hippocampus.After Dab2 expression,hippocampal TβRII and p-SMAD2/3 levels were significantly increased,while amyloid-beta deposition,microglia activation,tumor necrosis factor-βand interleulin-6 levels and neuronal loss were significantly attenuated in APP/PS1 mouse brain tissue.These results suggest that Dab2 can exhibit neuroprotective effects in Alzheimer’s disease by regulating TGF-β1/SMAD signaling. | Lei Song Yue Gu Jing Jie Xiaoxue Bai Ying Yang Chaoying Liu Qun Liu | 2014 | Neural Regeneration Research2014，9，1： | 4 |
| 19 | Spatial heterogeneity of a microbial community in Kongsfjorden,Svalbard during late summer 2006 and its relationship to biotic and abiotic factors显示文摘The 16S and 18S ribosomal ribonucleic acid genes of microbial organisms collected from the contrasting environments (temperature,salinity,silicate,phosphate and nitrate,p <0.05) of the inner and outer basins of Kongsfjorden (Spitsbergen,Arctic) were studied using polymerase chain reaction-denaturing gradient gel electrophoresis(DGGE) fingerprinting.Comparison of the microbial fingerprints and the physicochemical parameters revealed that molecular methodology exhibited a greater sensitivity.Sequences obtained from bacterial DGGE were affiliated with four main phylogenetic groups of bacteria:Proteobacteria(Alpha,Beta and Gamma),Bacteroidetes,Verrucomicrobia and Cyanobacteria.The relationships between the genotype distribution of these microbes and associated biotic/abiotic factors,revealed by canonical correspondence analysis,showed that Station 1 at 30 m (outer fjord) was grouped separately from the other sites.This difference could be a consequence of the thermocline and base of the euphotic layer at this depth where the Atlantic and Arctic-type waters overlapped. | GUO ChaoYing HE JianFeng ZHANG Fang CAI MingHong WANG GuiZhong | 2011 | Chinese Journal of Polar Science2011，22，1： | 3 |
| 20 | Large-scale Ni-MOF derived Ni_(3)S_(2) nanocrystals embedded in N-doped porous carbon nanoparticles for high-rate Na+ storage显示文摘Metal organic framework(MOF) has been confirmed as the promising precursor to develop the conve rsion-typed anode mate rials of sodium-ion batteries(SIBs) because of the tunable structure design and simple functional modification.Here,we prepare the ultrasmall Ni_(3)S_(2) nanocrystals embedded into N-doped porous carbon nanoparticles using the scalable Ni-MOF as precursor(denoted as Ni_(3)S_(2)@NPC).The ultrasmall size of Ni_(3)S_(2) can work for accelerated electro n/ion transfer to facilitate the electrochemical reaction kinetics.Moreover,the robust conductivity network originated from N-doped porous carbon nanoparticles can not only improve the electron conductivity,but also enhance the electrode integrity and stability of the electrode/electrolyte interface.In addition,the N heteroatoms provide extra Na storage sites.Accordingly,the electrode delivers the obviously competitive capacities and high-power output with respect to the currently reported Ni_(3)S_(2)/C composites.This study provides a scalable and universal strategy to develop the advanced transition metal sulfides for practically feasible SIBs. | Miao Yang Qiuli Ning Chaoying Fan Xinglong Wu | 2021 | Chinese Chemical Letters2021，32，2： | 3 |
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