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| 1 | Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘 | Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang | 2012 | Cellular & Molecular Immunology2012,9,3: | 18 |
| 2 | 复合钙钛矿太阳能电池电荷传输层材料研究进展显示文摘有机无机复合钙钛矿太阳能电池因具有适合的载流子扩散长度而成为备受关注的有望获得高效率的光伏器件。复合钙钛矿材料本身不含贵金属元素,可以采用液相法或物理气相法低温制备,成本低廉,但目前应用最多的电子传输层材料TiO2需400~500℃煅烧,与柔性基底及低温制备技术适应性差;空穴传输层材料SpiroOMeTAD合成工艺复杂,价格高昂,限制了复合钙钛矿太阳能电池的开发应用。开发和研究导电性好、成本低、稳定性好的电子和空穴传输层材料是复合钙钛矿太阳能电池研究中的一个非常重要的方面。综述了复合钙钛矿太阳能电池中电荷传输层材料的研究进展及发展方向。电子传输层材料方面通过对TiO2的改性以及与石墨烯的复合,采用ZnO、石墨烯或PCBM作为电子传输层材料,以与柔性基底及低温制备技术相适应。空穴传输层材料方面,采用其它低成本、导电性高的有机p型半导体替代spiro-OMeTAD;采用无机空穴传输层材料以避免有机空穴传输层材料的老化问题,提高电池的长期稳定性;利用复合钙钛矿材料兼作吸收层与空穴传输层,制备无空穴传输层材料结构电池以降低成本,提高稳定性。 | 陈建清 杨东辉 江静华 马爱斌 宋丹 Chaoying Ni Michael Z Hu | 2015 | 材料导报2015,29,5: | 4 |
| 3 | Non-small cell lung cancers(NSCLCs)oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors显示文摘With the continuous in-depth study of the interaction mechanism between viruses and hosts,the virus has become a promising tool in cancer treatment.In fact,many oncolytic viruses with selectivity and effectiveness have been used in cancer therapy.Human enterovirus is one of the most convenient sources to generate oncolytic viruses,however,the high seroprevalence of some enteroviruses limits its application which urges to exploit more oncolytic enteroviruses. | Bopei Cui Lifang Song Qian Wang Kelei Li Qian He Xing Wu Fan Gao Mingchen Liu Chaoqiang An Qiushuang Gao Chaoying Hu Xiaotian Hao Fangyu Dong Jiuyue Zhou Dong Liu Ziyang Song Xujia Yan Jialu Zhang Yu Bai Qunying Mao Xiaoming Yang Zhenglun Liang | 2023 | Signal Transduction and Targeted Therapy2023,8,10: | 0 |
| 4 | Characteristics of colistin-resistant Escherichia coli from pig farms in Central China显示文摘The emergence and dissemination of colistin resistance in Enterobacterioceae mediated by plasmid-borne mcr genes in recent years now pose a threat to public health.In this study,we isolated and characterized colistin-resistant and for mcr-positive£coli from pig farms in Central China.Between 2018 and 2019,594 samples were collected and recovered 445 E.coli isolates.Among them,33 with colistin resistance phenotypes and 37 that were positive for mcr genes were identified,including 34 positive for mcr-1,one positive for mcr-3,and two positive for both mcr-1 and mcr-3.An insertion of nine bases('CTGGATACG')into mcr-7 in four mcr-positive isolates led to gene dysfunction,and therefore did not confer the colistin resistance phenotype.Antimicrobial susceptibility testing revealed that 37 mcr-positive isolates showed severe drug resistance profiles,as 50% of them were resistant to 20 types of antibiotics.Multilocus sequence typing revealed a heterogeneous group of sequence types in mcr-positive isolates,among which ST10(5/37),ST156(5/37),and 5T617(4/37)were the predominant types.Plasmid conjugation assays showed that mcr-carrying plasmids of 25 mcr-positive isolates were conjugated with£coli recipient,with conjugation frequencies ranging from 1.7 × 10^(-6) to 4.1 × 10^(-3) per recipient.Conjugation of these mcr genes conferred a colistin resistance phenotype upon the recipient bacterium.PCR typing of plasmids harbored in the 25 transconjugants determined six types of plasmid replicons,including lncX4(14/25),FrepB(4/25),Incl2(3/25),lncHI2(2/25),FIB(1/25),and Inch(1/25).This study contributes to the current understanding of antibiotic resistance and molecular characteristics of colistin-resistant£coli in pig farms. | Zhong Peng Xiaoxue Zhang Xiaosong Li Zizhe Hu Zugang Li Chaoying Jia Menghong Dai Chen Tan Huanchun Chen Xiangru Wang | 2021 | Animal Diseases2021,1,2: | 0 |
| 5 | 卡培他滨联合奥沙利铂治疗进展期胃癌68例(英文)显示文摘Objective:The aim of this study was to evaluate the response rate,time to progression(TTP),overall survival,and safety of the combination of capecitabine plus oxaliplatin in treatment of advanced gastric cancer(AGC).Methods:All the patients with advanced gastric cancer who were not received any prior chemotherapy or radiotherapy were treated with combination of capecitabine(1250 mg/m2 twice daily,days 1-14) plus oxaliplatin(130 mg/m2 as a 2-h intravenous infusion on day 1) every 3 weeks.Results:Two cases of complete response(CR) and 34 cases of partial response(PR) were confirmed,giving an overall response rate of 52.9%,of the 68 patients with advanced gastric cancer.The median TTP and overall survival for all patients were 7.3 and 11.9 months,respectively.Grade 3 leukopenia,thrombocytopenia,nausea/vomiting,and diarrhea were observed in 3,5,1,and 4 patients,respectively.Yet,no grade 4 toxicity was observed.Conclusion:Capecitabine/ oxaliplatin combination chemotherapy is active in patients with advanced gastric cancer. | Chaoying Liu Jiang Li Runjie Wang Hong Hu Juanying Xu | 2009 | The Chinese-German Journal of Clinical Oncology2009,8,7: | 0 |