维普中文期刊产品整合服务
295篇 您的检索式:作者名="Chai Lin"
    题名 作者 年代 出处 被引量
1Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth显示文摘发信号的调停肽的 cell-to-cell 在植物在细胞的功能的协作和定义有关键角色。肽受体匹配为理解位于调停肽的发信号下面的机制是重要的。这里,我们报导根分裂组织生长的指导结构的鉴定为植物开发重要的因素(RGF ) 受体。基于签名 ligand 识别,主题(Arg-x-Arg ) 在充满白氨酸的重复受体 kinases (LRR-RKs ) 的一个亚科保存了的试金识别了机能上地 uncharacterized LRR-RK At4g26540 作为 RGF1 (RGFR1 ) 的受体。我们进一步在 2.6 Å 的一个决定与 RGFR1 的 LRR 领域在建筑群解决了 RGF1 的水晶结构;,它表明 Arg-x-Gly-Gly (RxGG ) 主题为由 RGFR1 的 RGF1 的硫酸盐组的特定的识别负责。基于 RxGG 主题,我们识别了另外四 RGFR。在导致 RGF 的发信号的五 RGFR 的参予被生物化学、基因的数据支持。我们也提供证明 SERK 为 RGF 作为合作受体工作的证据。一起拿,我们的学习识别 RGF 受体,能连接 RGF 的合作受体与他们的下游的部件发信号并且为与他们的肽 ligands 的 LRR-RKs 的基于结构的匹配提供原则的一个证明。Wen Song Li Liu Jizong Wang Zhen Wu Heqiao Zhang Jiao Tang Guangzhong Lin Yichuan Wang Xing Wen Wenyang Li Zhifu Han Hongwei Guo Jijie Chai 2016Cell Research2016,26,6:20
2Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases显示文摘Xiangxiu Liang Miaomiao Ma ,Zhaoyang Zhou Jinlong Wang Xinru Yang Shaofei Rao Guozhi Bi Lin Li Xiaojuan Zhang Jijie Chai She Chen Jian-Min Zhou 2018Cell Research2018,28,5:13
3Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009-2013显示文摘Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia 2017Chinese Medical Journal2017,,17:13
4A Survey on Human Performance Capture and Animation显示文摘与计算技术的快速的发展,三维(3D ) 人的身体模型和他们的动态运动是广泛地在数字娱乐使用工业。人的性能主要包含人的身体形状和运动。关键在人研究问题性能动画包括怎么捕获并且分析,并且怎么模仿人的身体静态的几何外观和人的身体的动态运动与物理效果打手势。在这调查,根据主要研究人的身体表演俘获和动画的方向,我们在关键研究总结最近的进展话题,也就是人身体表面重建,运动俘获和合成,以及基于物理的运动模拟,并且进一步讨论未来研究问题和方向。我们希望这将是有用的让阅读器有人的性能的全面理解捕获并且动画。Shihong Xia Lin Gao Yu-Kun Lai Ming-Ze Yuan Jinxiang Chai 2017Journal of Computer Science & Technology2017,32,3:12
5Crystal structure of PXY-TDIF complex reveals a conserved recognition mechanism among CLE peptide-receptor pairs显示文摘Heqiao Zhang Xiaoya Lin Zhifu Han Li-Jia Qu Jijie Chai 2016Cell Research2016,26,5:11
6SERK Family Receptor-like Kinases Function as Co-receptors with PXY for Plant Vascular Development显示文摘Heqiao Zhang Xiaoya Lin Zhifu Han Jizong Wang Li-Jia Qu Jijie Chai 2016Molecular Plant2016,9,10:11
7Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration显示文摘The capacity of 3D organoids to mimic physiological tissue organization and functionality has provided an invaluable tool to model development and disease in vitro.However,conventional organoid cultures primarily represent the homeostasis of self-organizing stem cells and their derivatives.Here,we established a novel intestinal organoid culture system composed of 8 components,mainly including VPA,EPZ6438,LDN193189,and R-Spondin 1 conditioned medium,which mimics the gut epithelium regeneration that produces hyperplastic crypts following injury;therefore,these organoids were designated hyperplastic intestinal organoids(Hyper-organoids).Single-cell RNA sequencing identified different regenerative stem cell populations in our Hyper-organoids that shared molecular features with in vivo injury-responsive Lgr5+stem cells or Clu+revival stem cells.Further analysis revealed that VPA and EPZ6438 were indispensable for epigenome reprogramming and regeneration in Hyper-organoids,which functioned through epigenetically regulating YAP signaling.Furthermore,VPA and EPZ6438 synergistically promoted regenerative response in gut upon damage in vivo.In summary,our results demonstrated a new in vitro organoid model to study epithelial regeneration,highlighting the importance of epigenetic reprogramming that pioneers tissue repair.Molong Qu Liang Xiong Yulin Lyu Xiannian Zhang Jie Shen Jingyang Guan Peiyuan Chai Zhongqing Lin Boyao Nie Cheng Li Jun Xu Hongkui Deng 2021Cell Research2021,31,3:9
8Differentiation of Hepatocellular Carcinoma from Hepatic Hemangioma and Focal Nodular Hyperplasia using Computed Tomographic Spectral Imaging显示文摘Background and Aims:Hepatocellular carcinoma(HCC)is the most common primary hepatic malignancy.This study was designed to investigate the value of computed tomography(CT)spectral imaging in differentiating HCC from hepatic hemangioma(HH)and focal nodular hyperplasia(FNH).Methods:This was a retrospective study of 51 patients who underwent spectral multiple-phase CT at 40–140 keV during the arterial phase(AP)and portal venous phase(PP).Slopes of the spectral curves,iodine density,water density derived from iodine-and water-based material decomposition images,iodine uptake ratio(IUR),normalized iodine concentration,and the ratio of iodine concentration in liver lesions between AP and PP were measured or calculated.Results:As energy level decreased,the CT values of HCC(n=31),HH(n=17),and FNH(n=7)increased in both AP and PP.There were significant differences in IUR in the AP,IUR in the PP,normalized iodine concentration in the AP,slope in the AP,and slope in the PP among HCC,HH,and FNH.The CT values in AP,IUR in the AP and PP,normalized iodine concentration in the AP,slope in the AP and PP had high sensitivity and specificity in differentiating HH and HCC from FNH.Quantitative CT spectral data had higher sensitivity and specificity than conventional qualitative CT image analysis during the combined phases.Conclusions:Mean CT values at low energy(40–90 keV)and quantitative analysis of CT spectral data(IUR in the AP)could be helpful in the differentiation of HCC,HH,and FNH.Weixia Li Ruokun Li Xiangtian Zhao Xiaozhu Lin Yixing Yu Jing Zhang Kemin Chen Weimin Chai Fuhua Yan 2021Journal of Clinical and Translational Hepatology2021,9,3:6
9Fluorescent co-localization of PTS1 and PTS2 and its application in analysis of the gene function and the peroxisomal dynamic in Magnaporthe oryzae显示文摘The peroxisomal matrix proteins involved in many important biological metabolism pathways in eukaryotic cells are encoded by nucleal genes, synthesized in the cytoplasm and then transported into the organelles. Targeting and import of these proteins depend on their two peroxisomal targeting signals (PTS1 and PTS2) in sequence as we have known so far. The vectors of the fluorescent fusions with PTS, i.e., green fluorescence protein (GFP)-PTS1, GFP-PTS2 and red fluorescence protein (RFP)-PTS1, were constructed and introduced into Magnaporthe oryzae Guy11 cells. Transformants containing these fusions emitted fluorescence in a punctate pattern, and the locations of the red and green fluorescence overlapped exactly in RFP-PTS1 and GFP-PTS2 co-transformed strains. These data indicated that both PTS1 and PTS2 fusions were imported into peroxisomes. A probable higher efficiency of PTS1 machinery was revealed by comparing the fluorescence backgrounds in GFP-PTS1 and GFP-PTS2 transformants. By introducing both RFP-PTS1 and GFP-PTS2 into Δmgpex6 mutants, the involvement of MGPEX6 gene in both PTS1 and PTS2 pathways was proved. In addition, using these transformants, the inducement of peroxisomes and the dynamic of peroxisomal number during the pre-penetration processes were investigated as well. In summary, by the localization and co-localization of PTS1 and PTS2, we provided a useful tool to evaluate the biological roles of the peroxisomes and the related genes.Jiao-yu WANG Xiao-yan WU Zhen ZHANG Xin-fa DU Rong-yao CHAI Xiao-hong LIU Xue-qin MAO Hai-ping QIU Yan-li WANG Fu-cheng LIN Guo-chang SUN 2008Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2008,9,10:6
10Introduction to Cloud Manufacturing显示文摘Cloud manufacturing is a new, networked and intelligent manufacturing model that is service-oriented, knowledge based, high performance, and energy efficient. In this model, state-of-the-art technologies such as informatized manufacturing, cloud computing, Internet of Things, semantic Web, and high-performance computing are integrated in order to provide secure, reliable, and high quality on-demand services at low prices for those involved in the whole manufacturing lifecycle. As an important part of cloud manufacturing, cloud simulation technology based on the COSIM-CSP platform has primarily been applied in the design of a multidisciplinary virtual prototype of a flight vehicle. This lays the foundation for further research into cloud manufacturing.Li Bohu Zhang Lin Chai Xudong 2010ZTE Communications2010,8,4:6
11Removing Endotoxin from Protein Solution by Chitosan Modified Affinity Membrane显示文摘Affinity membrane was prepared with chitosan immobilized on the hydrophile- modified poly(vinylidene fluoride) (PVDF) membrane. Fourier transform infrared spectroscopy (FTIR.) analysis indicated that the contents of —NH2 and —OH groups increased and fluoride decreased on the membrane surface after modification. Using this kind of affinity membrane, the effects of operation parameters such as pH, ionic strength and flow rate, on the amount of endotoxin removed were investigated. The results showed that the equilibrium adsorption capacity and the dissociation constant of the affinity membrane to endotoxin were 21.4 EU·mg-1 membrane and 0.50EU·ml-1, respectively, at pH 7.0 and ionic strength 0.2 mol·L-1. Adsorption appeared to follow a typical Langmuir adsorption isotherm. At pH 5.0, ionic strength of 0.2 mol·L-1, the removal rate of endotoxin from BSA solution with the chitosan affinity membrane was up to 88.6% (11.50 EU·mg-1 membrane), and the recovery of BSA was 93.4% (0.187mg·mg-1 membrane), while at pH 11.0, ionic strength of 0.2mol·L-1, the removal rate of endotoxin from lysozyme solution was 72.4% (9.92EU·mg-1 membrane), and the recovery of lysozyme was 92.3% (0.104 mg·mg-1 membrane).SUN Haixiang(孙海翔) ZHANG Lin(张林) CHAI Hong(柴红) CHEN Huanlin(陈欢林) 2005Chinese Journal of Chemical Engineering2005,13,4:5
12Efficacy and safety of micafungin for invasive candida infections:a meta-analysis of randomized controlled trials显示文摘象 candidiasis 那样的背景侵略真菌的感染和模子感染在严重有病的 patients.Micafungin 引起重要病态和死亡是有 Candida 和 Aspergillus.We 的种类做了这元分析澄清 micafungin 是否为治疗感染与另外的抗真菌的代理人相比提供优异功效和安全的对大多数的有势力活动的抗真菌的代理人与联系了的 echinocandin 我们做了使随机化的控制 tri 的元分析的侵略 candidiasis.Methods 随机效果的模型,或 1.20,95 CI 1.00-1.45 , P=0.0487 ) .In 增加, micafungin 是比为经历造血的干细胞移植的 neutropenic 病人的抗真菌的预防的比较仪更有效的(或 1.47,95 CI 1.08-2.00 , P=0.01 )在那里的 .Although 不以不利的药效果的发生是比较政体之间的重要差别(或 0.94,95 CI 0.77-1.11 ),因为不利事件,与 micafungin 对待的更少病人从研究撤退了(或 0.64,95Chen Qian Lin Mao-hu Chen Meng-li Liu Zhe-yuan Chai Dong Wang Rui 2012Chinese Medical Journal2012,,2:4
13Plasma αl-antitrypsin: A Neglected Predictor of Angiographic Severity in Patients with Stable Angina Pectoris显示文摘Background: As an acute phase protein, ct I-antitrypsin (AAT) has been extensively studied in acute coronary syndrome, but it is unclear whether a relationship exists between AAT and stable angina pectoris (SAP). The purpose of the present study was to investigate the association between AAT plasma levels and SAP. Methods: Overall, 103 SAP patients diagnosed by coronary angiography and clinical manifestations and 118 control subjects matched for age and gender were enrolled in this case-control study. Plasma levels of AAT, high-sensitivity C-reactive protein (hsCRP), lipid profiles and other clinical parameters were assayed for all participants. The severity of coronary lesions was evaluated based on the Gensini score (GS) assessed by coronary angiography. Results: Positively correlated with the GS (r = 0.564, P 〈 0.001), the plasma AAT level in the SAP group was significantly higher than that in the control group (142.08 ± 19.61 mg/dl vs. 125.50 ± 19.67 mg/dl, P 〈 0.001). The plasma AAT level was an independent predictor tbr both SAP (odds ratio [OR] = 1.037, 95% confidence interval [C/]: 1.020-1.054, P 〈 0.001) and a high GS (OR = 1.087, 95% CI: 1.051-1.124, P 〈 0.001) in a multivariate logistic regression model. In the receiver operating characteristic curve analysis, plasma AAT level was found to have a larger area under the curve (AUC) for predicting a high GS (AUC = 0.858, 95% CI: 0.788-0.929, P 〈 0.001 ) than that of hsCRP (AUC = 0.665, 95% CI: 0.557-0.773, P = 0.006; Z = 2.9363, P 〈 0.001), with an optimal cut-off value of 137.85 mg/dl (sensitivity: 94.3%, specificity: 68.2%). Conclusions: Plasma AAT levels correlate with both the presence and severity of coronary stenosis in patients with SAP, suggesting that it could be a potential predictive marker of severe stenosis in SAP patients.Hui Zhao Hong Liu Lin Chai Ping Xu Lu Hua Xiao-Yuan Guan Bing Duan Yi-Ling Huang Yi-Shi Li 2015Chinese Medical Journal2015,,6:4
14Cardioprotective mechanisms of salvianic acid A sodium in rats with myocardial infarction based on proteome and transcriptome analysis显示文摘Ischemic heart diseases(IHDs)cause great morbidity and mortality worldwide,necessitating effective treatment.Salvianic acid A sodium(SAAS)is an active compound derived from the well-known herbal medicine Danshen,which has been widely used for clinical treatment of cardiovascular diseases in China.This study aimed to confirm the cardioprotective effects of SAAS in rats with myocardial infarction and to investigate the underlying molecular mechanisms based on proteome and transcriptome profiling of myocardial tissue.The results showed that SAAS effectively protected against myocardial injury and improved cardiac function.The differentially expressed proteins and genes included important structural molecules,receptors,transcription factors,and cofactors.Functional enrichment analysis indicated that SAAS participated in the regulation of actin cytoskeleton,phagosome,focal adhesion,tight junction,apoptosis,MAPK signaling,and Wnt signaling pathways,which are closely related to cardiovascular diseases.SAAS may exert its cardioprotective effect by targeting multiple pathways at both the proteome and transcriptome levels.This study has provided not only new insights into the pathogenesis of myocardial infarction but also a road map of the cardioprotective molecular mechanisms of SAAS,which may provide pharmacological evidence to aid in its clinical application.Dan Jia Cheng-zhong Zhang Yan Qiu Xiao-fei Chen Lin Jia Alex F.Chen Yi-feng Chai Zhen-yu Zhu Jin Huang Chuan Zhang 2019Acta Pharmacologica Sinica2019,40,12:4
15Three new sesquiterpene alkaloids from the root of Tripterygium wilfordii显示文摘三新 sesquiterpene 碱, 1-desacetylwilforgine (1 ) , 1-desacetylwilforine (2 ) ,和 9 鈥 ? hydroxy-2-nicotinoylwilforine (3 ) 从 Tripterygium wilfordii 钩 f. 的根被孤立,与六已知的碱一起。他们的结构被建立根据光谱分析。Chun Min Wu Lin Mei Zhou Yi Feng Chai Yu Tian Wu Guo Rong Fan 2010Chinese Chemical Letters2010,21,7:4
16Selective feeding of bay scallop Argopecten irradians on phytoplankton community revealed by HPLC analysis of phytopigments in Bohai Sea, China显示文摘Understanding the feeding selectivity on phytoplankton by shellfi sh is currently a big challenge. In order to investigate the feeding behavior of bay scallop ( Argopecten irradians ) on phytoplankton, we compared its compositions of phytopigments in digestive glands with those in the surrounding seawater, and conducted fi ve consecutive investigations between July and November 2016 in a bay scallop culture area along coast of Qinghuangdao City, northwest of the Bohai Sea, China. Phytopigments in four-size fractionated phytoplankton of seawater (micro-(20-200 μm);nano(L)-[10-20 μm];nano(S)-[2.7-10 μm], and pico-[<2.7 μm]) and digestive glands of A . irradians were examined to investigate the selective feeding of A . irradians . Results show that fucoxanthin and peridinin constituted the major part of taxonomically diagnostic carotenoids (TDCs) in the micro- and nano(L)-phytoplankton in seawater. Compared with total phytoplankton biomass of seawater (TPB, sum of the four sizes), a substantial decrease of fucoxanthin proportion to total DCs in digestive glands was observed while that of peridinin, 19′-butanoyloxyfucoxanthin, alloxanthin and 19′-hexanoyloxy-fucoxanthin showed an obvious increase when those pigments were mainly confi ned to micro-sized phytoplankton (20-200 μm). However, zeaxanthin and prasinoxanthin were mainly confi ned to nano(s)- and pico-phytoplankton, of which the proportions in digestive glands were usually lower in TPB. The contribution of lutein to total DCs in digestive glands (with an average of 7.23%) increased compared with TPB of seawater (with an average of 0.63%) during all fi ve sampling times.JIANG Tao WANG Longhua ZHANG Fuchong FANG Xiao LU Lin ZHANG Jihong WANG Wei QU Keming CHAI Chao 2019Journal of Oceanology and Limnology2019,37,5:4
17Multidrug-resistant tuberculosis transmission among middle school students in Zhejiang Province,China显示文摘Background:Despite significant advancements in the treatment and diagnosis of tuberculosis(TB)over the past decade,drug-resistant TB remains an increasing threat to public health.TB outbreaks are most commonly reported in schools considering the delay in TB diagnosis,sustained contact,and overcrowding observed in schools.This report describes multidrug-resistant TB(MDR-TB)transmission in a school in Zhejiang Province.We aimed to raise awareness regarding MDR-TB transmission among students.Case presentation:The index patient was a 16-year-old girl in the second year of junior middle school in Zhejiang Province,China,who had been experiencing persistent cough and expectoration for 37 days since 1 March 2014.She tested positive for smear pulmonary and extrapulmonary TB on 8 April 2014 and was subsequently diagnosed with MDR-TB on 1 May 2014.However,the patient was resistant to isoniazid,rifampicin,ethambutol,and streptomycin.Thus,she was suspended from school for anti-TB treatment.All 54 students who were in close contact with the index patient in the same class were screened,and 5 tested positive on the tuberculin skin test.Their exposure time to the index patient was approximately 37 days.Three classmates were subsequently diagnosed with MDR-TB,with similar resistance profiles nearly two years later.Their average discovery delay was 55 days.These three classmates were also suspended from school for anti-TB treatment.During the treatment period,four students visited the local TB-designated hospital for further consultation every month and were followed up once a month by the local community health service center until they were completely cured.Conclusions:Discovery delay for an index patient played a primary role in MDR-TB transmission inside the school.To immediately detect TB,morning examinations in schools should be performed.TB trackers and case managers should work closely with public health workers and physicians in cases of TB outbreaks or transmissions involving students.Moreover,individuals who are in close contact with MDR-TB patients should undergo careful clinical follow-up for at least two years.Implementing a joint examination strategy to ensure early detection,diagnosis,and treatment of MDR-TB transmission is recommended.Yu Zhang Lin Zhou Zheng-Wei Liu Cheng-Liang Chai Xiao-Meng Wang Jian-Min Jiang Song-Hua Chen 2020Infectious Diseases of Poverty2020,9,3:4
18Microbial aerosol particles in four seasons of sanitary landfill site:Molecular approaches,traceability and risk assessment显示文摘Landfill sites are regarded as prominent sources of bioaerosols for the surrounding atmosphere.The present study focused on the emission of airborne bacteria and fungi in four seasons of a sanitary landfill site.The main species found in bioaerosols were assayed using high-throughput sequencing.The Source Tracker method was utilized to identify the sources of the bioaerosols present at the boundary of the landfill site.Furthermore,the health consequences of the exposure to bioaerosols were evaluated based on the average daily dose rates.Results showed that the concentrations of airborne bacteria in the operation area(OPA)and the leakage treatment area(LTA)were in the range of(4684±477)–(10883±1395)CFU/m^(3) and(3179±453)–(9051±738)CFU/m^(3),respectively.The average emission levels of fungal aerosols were 4026 CFU/m^(3) for OPA and 1295 CFU/m^(3) for LTA.The landfill site received the maximum bioaerosol load during summer and the minimum during winter.Approximately 41.39%–86.24%of the airborne bacteria had a particle size of 1.1 to 4.7μm,whereas 48.27%–66.45%of the airborne fungi had a particle size of more than 4.7μm.Bacillus sp.,Brevibacillus sp.,and Paenibacillus sp.were abundant in the bacterial population,whereas Penicillium sp.and Aspergillus sp.dominated the fungal population.Bioaerosols released from the working area and treatment of leachate were the two main sources that emerged in the surrounding air of the landfill site boundary.The exposure risks during summer and autumn were higher than those in spring and winter.Lin Li Jiawei Ma Kaixiong Yang Fengguang Chai Junxin Liu Xuesong Guo 2021Journal of Environmental Sciences2021,33,10:3
19Structural basis for specific self-incompatibility response in Brassica显示文摘自我障碍(SI ) 是在阻止自体受精的 flowering 植物的普遍机制并且使近交。在 Brassica,高度多态的 S 地点充满半胱氨酸的蛋白质的识别(SCR;或 S 地点蛋白质 11 ) 由同样多态的 S 地点受体, kinase (SRK ) 支配 SI 特性。这里,我们从 Brassica rapa 与 SCR9 在建筑群报导 SRK9 (eSRK9 ) 的细胞外的领域的水晶结构。SCR9 绑定导致 eSRK9 homodimerization,形成 2:2 eSRK : 有象信 A 一样的形状的 SCR heterotetramer。SCR9 的特定的识别通过三超(hv ) 被调停 eSRK9 的区域。每 SCR9 同时从第二 eSRK9 单体从一 eSRK9 单体和 hvII 的另外的一半与 hvII 的 hvI 和一个一半交往,起在调停的一个主要作用没有包含在二个 SCR9 分子之间的相互作用的 SRK9 homodimerization。为 eSRK9-SCR9 相互作用批评的残余的单个变化在 vitro 破坏他们的绑定。我们的学习文饰由 SRK 的 SCR 的特定的识别上的数据的身体并且为理解在 SRK 和 SCR 之间的合作进化提供一个结构的模板。Rui Ma Zhifu Han Zehan Hu Guangzhong Lin Xinqi Gong Heqiao Zhang June B Nasrallah Jijie Chai 2016Cell Research2016,26,12:3
20Phosphonate-Decorated Covalent Organic Frameworks for Actinide Extraction: A Breakthrough Under Highly Acidic Conditions显示文摘Although solid-phase extraction is a useful approach for metal ion separation from aqueous solutions,existing sorbents suffer from low extraction effici-encies and/or instability when in contact with strong acidic media.We report here the first study on rational design and fabrication of phosphonate-decorated covalent organic frameworks,COF-IHEP1 and COF-IHEP2,for efficient and selective extraction of of uranium(VI)[U(VI)]and plutonium(IV)[Pu(IV)]from highly acidic solutions.Jipan Yu Liyong Yuan Shuai Wang Jianhui Lan Lirong Zheng Chao Xu Jing Chen Lin Wang Zhiwei Huang Wuqing Tao Zhirong Liu Zhifang Chai John K.Gibson Weiqun Shi 2019CCS Chemistry2019,1,3:3
返回顶部 每页显示:
共15页 首页 上一页 第1页 下一页 末页 /15 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费