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| 1 | A deep learning-enabled portable imaging flow cytometer for cost-effective, highthroughput, and label-free analysis of natural water samples显示文摘We report a deep learning-enabled field-portable and cost-effective imaging flow cytometer that automatically captures phase-contrast color images of the contents of a continuously flowing water sample at a throughput of 100 mL/h.The device is based on partially coherent lens-free holographic microscopy and acquires the diffraction patterns of flowing micro-objects inside a microfluidic channel.These holographic diffraction patterns are reconstructed in real time using a deep learning-based phase-recovery and image-reconstruction method to produce a color image of each micro-object without the use of external labeling.Motion blur is eliminated by simultaneously illuminating the sample with red,green,and blue light-emitting diodes that are pulsed.Operated by a laptop computer,this portable device measures 15.5 cm×15 cm×12.5 cm,weighs 1 kg,and compared to standard imaging flow cytometers,it provides extreme reductions of cost,size and weight while also providing a high volumetric throughput over a large object size range.We demonstrated the capabilities of this device by measuring ocean samples at the Los Angeles coastline and obtaining images of its micro-and nanoplankton composition.Furthermore,we measured the concentration of a potentially toxic alga(Pseudo-nitzschia)in six public beaches in Los Angeles and achieved good agreement with measurements conducted by the California Department of Public Health.The cost-effectiveness,compactness,and simplicity of this computational platform might lead to the creation of a network of imaging flow cytometers for largescale and continuous monitoring of the ocean microbiome,including its plankton composition. | Zoltán Gӧrӧcs Miu Tamamitsu Vittorio Bianco Patrick Wolf Shounak Roy Koyoshi Shindo Kyrollos Yanny Yichen Wu Hatice Ceylan Koydemir Yair Rivenson Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 14 |
| 2 | Autosomal dominant in- heritance of congenital dislocation of the hip in 16 members of a fami- ly显示文摘 | Ceylaner G Ceylaner S Ustiinkan F | 2008 | Acta Orthop Traumatol Turc2008，42，： | 1 |
| 3 | Effects of simvastatin treatment on oxidant/ antioxidant state and ultrastructure of strepto-zotocin-diabetic rat lung显示文摘 | Ozansoy G Güven C Ceylan A | 2005 | Cell Biochem Funct2005，23，6： | 1 |
| 4 | Aspergillus pituitary abscess显示文摘 | A. C. Iplikcioglu S. Bek K. Bikmaz D. Ceylan C. A. G?kduman | 2004 | Acta Neurochirurgica2004，，5： | 1 |
| 5 | Scattered depressions with temporal preponderance in visual field test coexisting with optic disc temporal atrophy in cerebral arteriovenous malformation显示文摘 | Gokce G Oren NC Ceylan OM | | 0，，： | 1 |
| 6 | Long-time solutions to heat conduction transients with time-dependent inputs 显示文摘 | Ceylan H T G E Myers | 1980 | ASME Journal of Heat Transfer1980，102，1： | 1 |
| 7 | Apossible etiology of the internal derangement of thetemporomandibular joint based on the MRI observa-tions of the lateral pteiygoid muscle显示文摘 | Taskaya-Yilmaz N Ceylan G Incesu L | 2005 | Surg RadiolAnat2005，27，1： | 1 |
| 8 | Coagulopathy in multiple traumas 显示文摘 | Turtay M G Kirimlioglu V Ceylan C | 2010 | Ulus Travma Aeil Cerrahi Derg2010，16，3： | 1 |
| 9 | Arsenic related hearing loss in miners显示文摘 | Gülin G?k?en Kesici ?lhan ünlü Arzu Ba?türk Top?u Ceylan Demir Bal Engin Tutkun ?mer H?n? Y?lmaz | 2016 | American Journal of Otolaryngology--Head and Neck2016，，1： | 1 |
| 10 | OVULATION INDUCTION WITH GONADOTROPINS CAUSES INCREASED SISTER CHROMATID EXCHANGES显示文摘 | Tongu? E Ceylaner G Var T Zülfikaroglu E Ceylaner S | 2011 | Genetic Counseling2011，，2： | 1 |
| 11 | Traffic signal timing optimization based on genetic algorithm approach, including drivings routing显示文摘 | Ceylan H Bellm G H | 2004 | Transportation Research Part B2004，，38： | 1 |
| 12 | Diameters of the common bile duct in adults and postcholecystectomy patients: A study with 64-slice CT显示文摘 | Senem Senturk Tugba Cezlan Miroglu Aslan Bilici Hatice Gumus Rojbin Ceylan Tekin Faysal Ekici Güven Tekbas | 2010 | European Journal of Radiology2010，，： | 1 |
| 13 | A hybrid intrusion detection system design for computer network security 显示文摘 | AYDIN M A ZAIM A H CEYLAN K G | 2009 | Computers and Electrical Engineering2009，35，3： | 1 |
| 14 | Post abortion family planning counseling as a tool to increase contraception use 显示文摘 | Ceylan A Ertem M Saka G | 2009 | BMC Public Health2009，9，： | 1 |
| 15 | Emphasis of neutrophil-to-lymphocyte ratio in non-metastatic re- nal cell careinoma显示文摘 | Ceylan C Camtosun A Doluoglu O G | 2014 | Urologia2014，81，1： | 1 |
| 16 | A Hybrid Intrusion Detection System Design for Comuter Network Security显示文摘 | AYDIN M A ZAIM A H CEYLAN K G | 2009 | Computers and Electrical Engineering2009，35，3： | 1 |
| 17 | Influence of abutment material and luting cements color on the final color of all ceramics显示文摘 | Dede D 0 Armaganci A Ceylan G | 2013 | Acta Odontologica Scandinavica2013，71，6： | 1 |
| 18 | Traffic signal timing optimization based on genetic algorithm approach, including drivers' routing 显示文摘 | CEYLAN H BELL M G | 2004 | Transportation Res Part B2004，384，： | 1 |
| 19 | An investigation of the prevalence of depressive symptoms in newly recruited young adult men in Turkey显示文摘 | Tekbas OF Ceylan S Hamzao(g)lu O | 2003 | Psychiatry Res2003，119，12： | 1 |
| 20 | Hybrid intrusion detection system design for computer network security显示文摘 | Aydin M A Zaim A H Ceylan K G A | 2009 | Computers and Electrical Engineering2009，35，3： | 1 |
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