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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | Characterization and expression of recombination activating genes (RAG21 and RAG22) in Xenopus laevis 显示文摘 | Greenhalgh P CEM Olesen LA Steiner | 1993 | J Immunol1993，151，： | 1 |
| 3 | Review of paraffin deposition research under multiphase flow conditions 显示文摘 | Cem S Ekarit P | 2012 | Energy Fuels2012，26，： | 1 |
| 4 | The new energy hyperequation and its implication 显示文摘 | SOMA J CEM P E | 1985 | Energy Engineering1985，82，2： | 1 |
| 5 | Immunolo- calization of peroxisome proliferators - activated receptors and retinoid X receptors in the adult rat CNS 显示文摘 | Moreno S Farioli - Vecchioli S Cem M P | 2004 | Neu- roscience2004，123，1： | 1 |
| 6 | Assess- ment of precious metal flows during preprocessing of waste electrical and electronic equipment显示文摘 | Chancerel P Meskers CEM Hageluken Ch | 2009 | Journal of Industrial Ecology2009，13，5： | 1 |
| 7 | The effect of channel height on the enhanced heat transfer characteristics in a corrugated heat exchanger channel显示文摘 | Yasar I Cem P | 2003 | Appl Thermal Eng2003，23，8： | 1 |
| 8 | Urothelial neoplasms of the kidneyand ureter:an epidemiologic,pathological and clinical review显示文摘 | Oorter CC R P Latchamsettyk CEM Genega etal | 2005 | AUA Update series2005，24，： | 1 |
| 9 | Prognostic value of gross tumor vol- ume delineated by FDG - PET - CT based radiotherapy treatment planning in patients with locally advanced pancreatic cancer treated with chemoradiotherapy 显示文摘 | Cem P Erkan T Cem O | 2012 | Rad Oncol2012，7，1： | 1 |
| 10 | Cytokines in the rheumatic diseases 显示文摘 | William P A Cem G | 2004 | Rheumatic Disease Clinics of North America2004，30，1： | 1 |
| 11 | Slug flow modeling for downward inclined pipe flow:theoretical considerations显示文摘 | TAITEL YEHUDA CEM SARICA BRILL J P | 2000 | Int J Muhiphase Flow2000，26，5： | 1 |
| 12 | Constrictive pericarditis: risks, aetiologies and outcomes after total pericardiectomy: 24 years of experience ? 显示文摘 | Gá bor Szabó Bastian Schmack Cem Bulut Pá l Soó s Alexander Weymann Susanne Stadtfeld Matthias Karck | 2013 | European Journal of Cardio-Thoracic Surgery2013，，6： | 1 |
| 13 | Multi-aspect analysis of ureteral access sheath usage in retrograde intrarenal surgery: A RIRSearch group study显示文摘Objective:To evaluate the effect of ureteral access sheath(UAS)use and calibration change on stone-free rate and complications of retrograde intrarenal surgery(RIRS).Methods:Data from 568 patients undergoing RIRS for kidney or upper ureteral stones were retrospectively included.Firstly,patients were compared after 1:1 propensity score matching,according to UAS usage during RIRS(UAS used[+]87 and UAS non-used[−]87 patients).Then all UAS+patients(n=481)were subdivided according to UAS calibration:9.5-11.5 Fr,10-12 Fr,11-13 Fr,and 13-15 Fr.Primary outcomes of the study were the success and complications of RIRS.Results:Stone-free rate of UAS+patients(86.2%)was significantly higher than UAS−patients(70.1%)after propensity score matching(p=0.01).Stone-free rate increased with higher caliber UAS(9.5-11.5 Fr:66.7%;10-12 Fr:87.0%;11-13 Fr:90.6%;13-15 Fr:100%;p<0.001).Postoperative complications of UAS+patients(11.5%)were significantly lower than UAS−patients(27.6%)(p=0.01).Complications(8.7%)with 9.5-11.5 Fr UAS was lower than thicker UAS(17.2%)but was not statistically significant(p=0.09).UAS usage was an independent factor predicting stone-free status or peri-and post-operative complications(odds ratio[OR]3.654,95%confidence interval[CI]1.314-10.162;OR 4.443,95%CI 1.350-14.552;OR 4.107,95%CI 1.366-12.344,respectively).Conclusion:Use of UAS in RIRS may increase stone-free rates,which also increase with higher caliber UAS.UAS usage may reduce complications;however,complications seemingly increase with higher UAS calibration. | OktayÖzman HacıM.Akgül Cem Başataç ÖnderÇınar Eyüp B.Sancak Cenk M.Yazıcı BülentÖnal Haluk Akpınar on behalf of the RIRSearch Study Group | 2024 | Asian Journal of Urology2024，11，1： | 0 |
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