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| 1 | Clindamycin-induced acute cholestatic hepatitis显示文摘我们为牙齿的感染在 clindamycin 的管理以后在一个 42 岁的女人报导尖锐 hepatotoxicity 的一个案例。在治疗的 6 d 以后,她有疲劳,恶心,呕吐,厌食,瘙痒和黄疸。她的实验室分析显示出丙氨酸 aminotransferase (中高音) , 1795 IU/L (正常范围 0-40 ) ;aspartate aminotransferase (著名计算机生产厂商) , 1337 IU/L (正常范围 5-34 ) ;硷性磷酸酯酶(高山) , 339 IU/L (正常范围 40-150 ) ;gamma-glutamyl transpeptidase (GGT ) , 148 IU/L (正常范围 9-64 IU/L ) ;全部的胆红素, 4.1 mg/dL;直接胆红素, 2.9 mg/dL 和前凝血酶时间(磅) , 13.5 s 与国际规范的比率(INR ) , 1.04。她被就医,与立即的药中止。她的肝活体检视标本显示出混合类型(肝细胞和胆汁郁积的) 肝的损害,与导致药的肝炎的诊断兼容。用 Naranjo 概率规模的一个客观诱发性评价建议 clindamycin 是尖锐肝炎的可能的原因。在易受影响的个人, clindamycin 使用可以导致尖锐混合类型肝毒性。如果在严重肝损伤被建立以前,这药被中止,完全的恢复可能是可能的。 | Cem Aygün Orhan Kocaman Yesim Gürbüz mer Sentürk Sadettin Hülagü | 2007 | World Journal of Gastroenterology2007，13，40： | 6 |
| 2 | Hepatic cystic echinococcosis:Percutaneous treatment as an outpatient procedure显示文摘Objective:To demonstrate utility and safety of the puncture aspiration injection and reospiration(PAIR)technique for outpatients.Methods:Percutaneous treatment with US guidance was applied to 33 patients for 44 cysts.Patients treated with the PAIR technique,were outpatients.PAIR and catheterization technique were evaluated for efficacy and safety of procedure and complication rates.Results:Thirty-five of 44 cysts were treated with the PAIR and 9 of 44 were treated with the catheterization technique.The success rate of the cysts Gharbi type 1(CEI)and type 2(Ct3a)treated with the PAIR technique was 1009.hi the follow up of 9 cysts treated with the catheterization technique,2 of them(22%)developed cyst infection and 1(11%)developed a biliary fistula.Conclusions:The PAIR technique was found to be an effective and safe approach in order to treat Gharbi type 1 and type 2 cysts percutaneously for outpatients.It has a very low complication rate in comparison with the catheterization technique.So every effort should be mode to finish the treatment with PAIR technique. | Mert Kroglu Bekir Erol Cemil Gürses Baris Türkbey Cem Yunus Bas Ahmet Sükrü Alparslan Banu Kale Kroglu Iclal Erdem Toslak Bülent eki Okan Akhan | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，3： | 4 |
| 3 | Plasma and aqueous humor levels of adiponutrin and pannexin 1 in patients with and without diabetic retinopathy显示文摘AIM: To evaluate plasma and aqueous levels of adiponutrin and pannexin 1 in patients with and without diabetic retinopathy.METHODS: The study included three age and gendermatched groups of 20 cataract patients with no diabetes or additional disease(Group C), 20 cataract patients with diabetes and no retinopathy(Group DM+C), and 20 cataract patients with diabetic retinopathy(Group DR+C).All the patients were examined with respect to body mass index(BMI), fasting plasma glucose, hemoglobin A1c(HbA1c), and lipid profile.Phacoemulsification and intraocular lens(Phaco+IOL) implantation were performed to all patients in all the groups, and aqueous samples were taken during the operation.The plasma and aqueous adiponutrin and pannexin 1 levels were analyzed using enzyme-linked immunosorbent assays.RESULTS: A statistically significant difference was determined between the groups with respect to BMI, fasting plasma glucose, and HbA1c levels(P<0.05 for all parameters tested).The plasma adiponutrin levels of Group DR+C were statistically significantly lower than those of Group C and Group DM+C(P<0.001, P=0.004).No statistically significant difference was determined in the aqueous adiponutrin levels in three groups.The plasma pannexin 1 levels of Groups DM+C and DR+C were statistically significantly lower than those of Group C(both P=0.001).The aqueous pannexin 1 levels of Group DR+C were statistically significantly higher than those of Group C and Group DM+C(P=0.001, P<0.001).CONCLUSION: Adiponutrin and pannexin 1, which play an important role in the pathophysiology of diabetes and obesity, and have a regulatory role in hyperglycemia and insulin resistance.The measurement of adiponutrin and pannexin 1 levels may support clinicians in determining the risk of DR development. | Fatih Cem Gül Sabiha Güngör Kobat FatihÇelik Süleyman Aydin Ramazan Fazil Akkoç | 2022 | International Journal of Ophthalmology(English edition)2022，15，3： | 3 |
| 4 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 5 | Molecular cloning and characterization of STAMP1,a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer显示文摘 | Kemal S Cem E Ceren G | 2002 | Cancer Res2002，277，36： | 1 |
| 6 | The effect of nitrogen fertilization on tocopherols in rapeseed genotypes显示文摘 | Cem (O)mer Egesel M Kemal Gül Fatih Kahr man | | 0，，03： | 1 |
| 7 | Using Raman Spectroscopy for Determination Methanol Quantity in Illegal Alcoholic Beverages显示文摘Illegal production of alcoholic beverages is a common problem in most countries.The consumption of these counterfeit alcoholic products in Turkey has increasingly been one of the major health concerns.In this study,a comparison between GC-MS and Raman spectroscopy techniques was made to determine the amount of methanol in BogmaRaki which is a counterfeit alcoholic beverage produced and consumed in Hatay region.Different ratios of methanol/ethanol concentrations were prepared to obtain a calibration curve.This curve was used to measure the amount of methanol in the actual product samples using both GC-MS and Raman spectroscopy techniques.Results obtained from both techniques were compared using Paired sample t-tests.The Limit of Detection and the Limit of Quantification values were determined as 0.03(%v/v) and 0.11(%v/v),respectively.Both techniques demonstrated a similar sensitivity in the determination of methanol concentration in these counterfeit products(p>0.05).Raman Spectroscopy,however,has an advantage of being easy to use,inexpensive,rapid and non-destructive analytical technique with little or no sample preparation. | Cem ZEREN Günes ACIKGOZ Süleyman KAHRAMAN | 2017 | 光谱学与光谱分析2017，37，9： | 1 |
| 8 | Rheological properties of reduced-fat and low-fat ice cream containing whey protein isolate and inulin显示文摘 | Ay?e Sibel Akal?n Cem Karag?zlü Gülfem ünal | | European Food Research and Technology0，，： | 1 |
| 9 | Planning multiple paths with evolutionary speciation显示文摘 | CEM H G ARTHUR C S | 2001 | IEEE Transactions on Evolutionary Computation2001，6，3： | 1 |
| 10 | An Extended 10-Core Transrectal Ultrasonography Guided Prostate Biopsy Protocol Improves the Detection of Prostate Cancer显示文摘 | Saadettin Yilmaz Eskicorapci Dilek Ertoy Baydar Cem Akbal Mustafa Sofikerim Mert Günay Sinan Ekici Haluk Ozen | 2003 | European Urology2003，，4： | 1 |
| 11 | Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice显示文摘 | Furuhashi Masato Fucho Raquel G?rgün Cem Z Tuncman Gürol Cao Haiming Hotamisligil G?khan S | 2008 | Journal of Clinical Investigation2008，，7： | 1 |
| 12 | Acute phase proteins and other systemic responses to inflammation显示文摘 | Cem G M D Irving K M D | 1999 | Mechanisms of Disease1999，340，： | 1 |
| 13 | Successful management of cryoglobulinemia-induced leukocytoclastic vasculitis with thalidomide in a patient with multiple myeloma 显示文摘 | Cem ArM Soysal T Hatemi G | 2005 | Ann Hematol2005，84，9： | 1 |
| 14 | Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis显示文摘 | Takahisa Nakamura Masato Furuhashi Ping Li Haiming Cao Gurol Tuncman Nahum Sonenberg Cem Z. Gorgun G?khan S. Hotamisligil | 2010 | Cell2010，，3： | 1 |
| 15 | Restoration of collagen formation in photodramaged human skin by tretion显示文摘 | Griffiths CEM Russman AN Majmudar G | 1993 | New Engl J Med1993，329，： | 1 |
| 16 | Exploratory spatial data analysis of the distribution of regional per capita GDP in Europe,1980-1995显示文摘 | JULIE L G CEM E | 2003 | Papers in Regional Science2003，82，： | 1 |
| 17 | Pricing and power control in a multicell wireless data network显示文摘 | CEM U S NARAYAN B M DAVID J G | 2001 | IEEE Journal on Selected Areas in Communications2001，19，10： | 1 |
| 18 | Multi-DSP and -FPGA-based fully digital control system for cascaded multilevel converters used in FACTS applications 显示文摘 | Tevhid A Mustafa D Cem 0 G | 2012 | IEEE Trans on Industry Applications2012，8，3： | 1 |
| 19 | Plasma kinetic vaporization of the prostate: clinical evaluation of a new technique 显示文摘 | Cetin D MuratS Cem G | 2004 | J Eudouro2004，18，： | 1 |
| 20 | Is Rectal Washout Necessary in Anterior Resection for Rectal Cancer? A Prospective Clinical Study显示文摘 | Cem Terzi MD Tarkan ünek MD ?zgül Sa?ol MD Tu?bahan Y?lmaz MD Mehmet Füzün MD Selman S?kmen MD Gül Erg?r MD Ali Küpelio?lu MD | 2006 | World Journal of Surgery2006，，2： | 1 |
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