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| 1 | Convective high-speed flow and field-aligned high-speed flows explored by TC-1显示文摘From June 1, 2004 to October 31, 2006, a total 465 high-speed flow events are observed by the TC-1 satellite in the near-Earth region (?13 RE < x < ?9 RE, |Y |<10 RE, |Z|<5 RE). Based on the angle between the flow and the magnetic field, the high-speed flow events are further divided into two types, that is, field-aligned high-speed flow (FAHF) in the plasma sheet boundary and convective bursty bulk flow (BBF) in the center plasma sheet. Among the total 465 high-speed flow events, there are 371 FAHFs, and 94 BBFs. The CHF are mainly concentrated in the plasma sheet, the intersection angle between the flow and the magnetic field is larger, the magnetic field intensity is relatively weak. The FHF are mainly distributed near the boundary layer of the plasma sheet, the intersection angle between the flow and magnetic field is smaller, and the magnetic field intensity is relatively strong. The convective BBFs have an important effect on the substorm. | ZHANG LingQian LIU ZhenXing MA ZhiWei W. BAUMJOHANN M.W. DUNLOP WANG GuangJun WANG Xiao H. REME C. CARR | 2008 | Chinese Science Bulletin2008，53，15： | 5 |
| 2 | MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer显示文摘Despite tremendous efforts from scientists and clinicians worldwide, pancreatic adenocarcinoma(PDAC) remains a deadly disease due to the lack of early diagnostic tools and reliable therapeutic approaches. Consequently, a majority of patients(80%) display an advanced disease that results in a low resection rate leading to an overall median survival of less than 6 months. Accordingly, robust markers for the early diagnosis and prognosis of pancreatic cancer, or markers indicative of survival and/or metastatic disease are des-perately needed to help alleviate the dismal prognosis of this cancer. In addition, the discovery of new therapeutic targets is mandatory to design effective treatments. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for PDAC. | Marion Gayral Sébastien Jo Naima Hanoun Alix Vignolle-Vidoni Hubert Lulka Yannick Delpu Aline Meulle Marlène Dufresne Marine Humeau Maёl Chalret du Rieu Barbara Bournet Janick Sèlves Rosine Guimbaud Nicolas Carrère Louis Buscail Jérome Torrisani Pierre Cordelier | 2014 | World Journal of Gastroenterology2014，20，32： | 4 |
| 3 | 女性健康倡议单用雌激素试验中冠状动脉钙化与试验后心血管事件及死亡率的关系显示文摘参与女性健康倡议(women’s health initiative,WHI)单用雌激素(estrogen—alone,E—Alone)试验的年龄50~59岁的女性中,与安慰剂组相比,基线时随机使用合成雌激素的女性心肌梗死的风险和死亡率更低。 | 黄洁 叶鹏 Poornima IG Mackey RH Allison MA Manson JE Carr JJ LaMonte MJ Chang Y Kuller LH | 2017 | 中华高血压杂志2017，25，11： | 3 |
| 4 | Diet,Escherichia coli O157:H7,and cattle:a review after 10 years显示文摘 | Callaway TR Carr MA Edrington TS | 2009 | Curr Issues Mol Biol2009，11，2： | 1 |
| 5 | Artificial reefs: the importance of comparisons with natural显示文摘 | MH Carr MA Hixon | 1997 | Fisheries1997，22，4： | 1 |
| 6 | MicroRNA-21 Is Induced Early in Pancreatic Ductal Adenocarcinoma Precursor Lesions显示文摘 | du Rieu Ma?l Chalret Torrisani Jér?me Selves Janick Al Saati Talal Souque Anny Dufresne Marlène Tsongalis Gregory J Suriawinata Arief A Carrére Nicolas Buscail Louis Cordelier Pierre | 2010 | Clinical Chemistry2010，，： | 1 |
| 7 | Diabetes mellitus:A hypercoagulable state显示文摘 | | 2001 | J Diabetes Complications2001，15，： | 1 |
| 8 | Dopaminergic toxicity of the herbicide atrazine in rat striatal slices 显示文摘 | Filipov NM Stewart MA Carr RL | 2007 | Toxicology2007，232，12： | 1 |
| 9 | Protein biomarker discov?ery and validation: the long and uncertain path to clinical utility显示文摘 | Rifai N Gillette MA Carr SA | 2006 | Nat Biotechnol2006，24，8： | 1 |
| 10 | Response to McAvoy and Tudor-Locke on their commentary on our manuscript:“Association of accelerometer-derived step volume and intensity with hospitalizations and mortality in older adults:A prospective cohort study”显示文摘Dear Editor,We have read with interest the commentary by McAvoy and Tudor-Locke on our article entitled 'Association of accelerometer-derived step volume and intensity with ho spitalizations and mortality in older adults:A prospective cohort study'. The authors expressed some concerns about our methodology used to define accelerometer-derived step intensity and the analytical approach applied in our study. | Asier Mañas Borja del Pozo Cruz Ulf Ekelund JoséLosa Reyna Irene Rodríguez Gómez JoséAntonio Carnicero Carreño Leocadio Rodríguez Mañas Francisco J.García García Ignacio Ara | 2022 | Journal of Sport and Health Science2022，11，6： | 1 |
| 11 | Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health Initiative 显示文摘 | Manson JE Allison MA Carr JJ | 2010 | Menopause2010，17，4： | 1 |
| 12 | A randomized,double-blind,placebo-controlled parallel-group study to assess the efficacy and safety of nebivolol,a novel β-blocker,in patients with mild to moderate hypertension显示文摘 | Weiss RJ Weber MA Carr AA | 2007 | J Clin Hypertens(Greenwich)2007，9，9： | 1 |
| 13 | Application of silica-based hyper-crosslinked sulfonate-modified re-versed stationary phases for separating highly hydrophil-ic basic compounds显示文摘 | Luo H Ma L Paek C Carr PW | 2008 | J Chromatogr A2008，1202，1： | 1 |
| 14 | Transforming growth factor alpha (TGFalpha) in hepatocellular carcinomas and adjacent hepatic parenchyma显示文摘 | Nalesnik MA Lee RG Carr BI | 1998 | Hum Pathol1998，29，3： | 1 |
| 15 | High-resolution breath-hold contrast-enhanced MR angiography of the entire carotid circulation显示文摘 | Carr J Ma J Desphande V | 2002 | AJR Am J Roentgenol2002，178，3： | 1 |
| 16 | Diabetes mellitus:A hypewoagulalle state显示文摘 | | 2001 | Diabetes omplications2001，15，1： | 1 |
| 17 | Does the context of spousal loss affect the physi- cal functioning of older widowed persons? a longitudinal analysis 显示文摘 | Lee MA Carr D | 2007 | Research on Aging2007，29，5： | 1 |
| 18 | Protein biomarker discovery and valida- tion: the long and uncertain path to clinical utility显示文摘 | Rifai N Gillette MA Carr SA | 2006 | Nat Biotechnol2006，24，8： | 1 |
| 19 | Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine显示文摘 | Esteve MA Carre M Bourgarel-Rey V | 2006 | Mol Cancer Ther2006，5，： | 1 |
| 20 | Acceler ated chilling of carcasses to improve pork quality显示文摘 | Springer MP Carr MA Ramsey CB | 2003 | Journal of Animal Science2003，81，： | 1 |
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