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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | The effect of removal of seminal plasma, egg yolk level and season on sperm freezabili- ty of Canary buck (Capra hircus) 显示文摘 | Cabrera F Gonzfdez F Batista M | 2005 | Reprod Dom Anim2005，40，3： | 1 |
| 3 | Determinants of individual engagement in knowledge sharing显示文摘 | Cabrera A Collins W C Salgado J F | 2006 | International Journal of HumanResource Management2006，17，2： | 1 |
| 4 | Different patterns of HLA - DR antigen expression in normal epithelium ,hyperplastic and neoplastic malignant lesions of the breast显示文摘 | Concha A Ruiz- Cabello F Cabrera T | 1995 | Eur J Immunogenet11995，22，4： | 1 |
| 5 | Knowledge sharing dilemmas显示文摘 | Cabrera A Cabrera E F | | 0，，05： | 1 |
| 6 | Treatment of ureteral lithiasis with shock waves显示文摘 | Gonzalez Enquita C Cabrera Perez J Calahorra Fernandez F J | 2001 | Arch Esp Urol2001，54，9： | 1 |
| 7 | Fostering knowledge sharingthrough people management practices 显示文摘 | Cabrera E F Cabrera A | 2005 | InternationalJournal of Human Resource Management2005，16，： | 1 |
| 8 | Aggregate-protected and unprotected organic matter pools in conventional and no-tillage soils 显示文摘 | BEARE M H HENDRIX P F CABRERA M L | 1994 | Soil Science Society of America Journal1994，58，3： | 1 |
| 9 | An Expert HR System for Aligning Organizational Culture and Strategy 显示文摘 | Cabrera E F Bonache J | 1999 | Human Resource Planning1999，22，1： | 1 |
| 10 | Implications for immunosurveillance of altered HLA class Ⅰ phenotypes in human tumors显示文摘 | Garrido F Ruiz-Cabello F Cabrera T | 1997 | Immunol Today1997，18，： | 1 |
| 11 | Aggregate-protected and unprotected organic matter pools in conventional-tillage and no-tillage soils显示文摘 | Beate M H Cabrera M L Hendrix P F | 1994 | Soil Sci Soc Am J1994，58，： | 1 |
| 12 | Fostering knowledge sharing through people management practice显示文摘 | Cabrera E F Cabrera A | 2005 | The International Journal of Human Resource Management2005，16，5： | 1 |
| 13 | Natural history of HLA expression during tumor development显示文摘 | Garrido F Cabrera T Concha A | 1993 | Immunol Today1993，14，： | 1 |
| 14 | Metal concentrations in scleractionean corals determined by instrumental neutron activation analysis and atomic absorption spectro-metry显示文摘 | Saunders M G Cabrera M E M Peraza E F H | 1997 | Journal of Radioanalytical and Nuclear Chemistry1997，219，： | 1 |
| 15 | Metal accumulation in soil after application of municipal solid waste compost under intensive farming conditions 显示文摘 | Madrid F Lopez R Cabrera F | 2007 | Agric Ecosyst Environ2007，119，34： | 1 |
| 16 | Implications for immunosurveillance of altered HLA class Ⅰ phenotypes in human tumours显示文摘 | Garrido F Ruiz-Cabello F Cabrera T | 1997 | Immunol Today1997，18，2： | 1 |
| 17 | Knowledge-sharing dilemmas显示文摘 | Cabrera A Cabrera E F | | 0，，05： | 1 |
| 18 | Knowledge-sharing dilemmas 显示文摘 | CABRERA A CABRERA E F | 2002 | Organization Studies2002，，5： | 1 |
| 19 | Changes in enzyme activities and microbial biomass after 'in situ'remediation of a heavy metal-contaminated soil显示文摘 | PEREZ-DE-MORA A ORTEGA-CALVO J J CABRERA F | 2005 | Applied Soil Ecology2005，28，12： | 1 |
| 20 | Determinants of individual engagement in knowledge sharing 显示文摘 | Cabrera A Collins W C Salgado J F | 2006 | The International Journal of Human Resource Management2006，，2： | 1 |
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