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| 1 | Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition显示文摘尽管在基因倡导者区域的 DNA methylation 的函数很好在 transcriptional 压抑被建立,在基因身体区域的 DNA methylation 的 evolutionarily 保存的普遍分发的函数仍然保持不完全地理解。这里,我们证明 DNA methylation 在包括的或者拼接的 exons (ASEs ) 被充实,并且 DNA methylation 的那抑制导致 ASEs 的异常拼接。methyl-CpG-binding 蛋白质 MeCP2 在包括的 ASEs 被充实,特别地也是的那些高度, DNA methylation 的 methylated,和抑制破坏到 exons 的 MeCP2 的特定的指向。有趣地, MeCP2 的脱离导致增加的 histone acetylation 和异常跳过 ASE 事件。我们进一步显示出那显示出的活动导致 exon 跳过的 histone deacetylase (HDAC ) 的那抑制有那的重叠的高度重要的度由 MeCP2 引起了击倒。一起,我们的数据显示 DNA methylation 在 exon 定义操作调制拼接的其他的 RNA 的那 intragenic 并且能经由多功能的蛋白质 MeCP2 的招募提高 exon 识别,它从而通过 HDAC 的随后的招募维持本地 histone hypoacetylation。 | Alika K Maunake Iouri Chepelev Kairong Cui Keji Zhao | 2013 | Cell Research2013，23，11： | 19 |
| 2 | A BAC clone of MDV strain GX0101 with REV-LTR integration retained its pathogenicity显示文摘The complete genome of Marek's disease virus (MDV) strain GX0101, which was integrated with the LTR sequences of REV, was cloned in Escherichia coli as a bacterial artificial chromosome (BAC). BAC vector sequences were introduced into the US2 locus of the MDV genome by homologous recombination. The viral DNA containing the BAC vector was used to transform Escherichia coli strain of DH10B. Then the recombinant virus was successfully rescued by transfection of the recombinant BAC DNA into primary chicken embryo fibroblast (CEF). This BAC viral clone was named bac-GX0101. When the reconstituted virus was inoculated into 1-day-old birds, visceral tumors could be detected as early as 62 d post infection. There was no difference in growth ability and pathogenicity to birds between the BAC derived virus and its parental virus. The BAC derived virus maintained its oncogenicity and immunosuppressive effects. In conclusion, the complete genome of GX0101 strain was successfully cloned into BAC and the infectious clone was rescued. With the powerful BAC manipulation system, the infectious clone will provide a useful tool for further understanding the functional roles of the inserted REV-LTR sequence in the GX0101 strain of MDV. | SUN AiJun LAWRENCE Petherbridge ZHAO YuGuang LI YanPeng NAIR Venugopal K CUI ZhiZhong | 2009 | Chinese Science Bulletin2009，54，15： | 15 |
| 3 | Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography显示文摘Objective The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography(OCTA) based on optical microangiography(OMAG) measurements of macular vessels in normal eyes. Methods In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA(Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network: vessel area density(VAD), vessel skeleton density(VSD), vessel diameter index(VDI), vessel perimeter index(VPI), vessel complexity index(VCI), flux, and foveal avascular zone(FAZ). Coefficient of variation(CV) and intraclass correlation coefficient(ICC) were calculated for evaluating intravisit and intervisit repeatability, as well as interobserver reproducibility. Results The measurements showed high repeatability [CVs ≤ 4.2%(intravisit) and ≤ 4.6%(intervisit)] and interobserver reproducibility(ICCs ≥ 0.923) for all parameters. Conclusion This study demonstrated good repeatability and reproducibility of OCTA based on OMAG for the measurement of superficial vessel parameters in normal eyes. | ZHAO Qi YANG Wen Li WANG Xiao Na Ruikang K Wang YOU Qi Sheng CHU Zhong Di XIN Chen ZHANG Meng Yu LI Dong Jun WANG Zi Yang CHEN Wei LI Yi Feng CUI Rui SHEN Lin WEI Wen Bin | 2018 | Biomedical and Environmental Sciences2018，31，6： | 8 |
| 4 | Taxonomy and phylogeny of the brown-rot fungi:Fomitopsis and its related genera显示文摘Taxonomic and phylogenetic studies on the brown-rot fungi,Fomitopsis and its related genera,are carried out.On the basis of morphological characters and phylogenetic evidence of DNA sequences of multiple loci including the internal transcribed spacer(ITS)regions,the large subunit nuclear ribosomal RNA gene(nLSU),the small subunit nuclear ribosomal RNA gene(nSSU),the small subunit mitochondrial rRNA gene sequences(mtSSU),the translation elongation factor 1-αgene(tef1)and the second subunit of RNA polymerase II(rpb2),six new genera,Fragifomes,Niveoporofomes,Piptoporellus,Rhodofomitopsis,Rubellofomes and Ungulidaedalea are established.Four new species,Buglossoporus eucalypticola,Daedalea allantoidea,Piptoporellus hainanensis and P.triqueter are descibed from China.Illustrated descriptions of the novel species are provided.Identification keys to Fomitopsis and its related genera,as well as keys to the species of each genus are provided. | Mei-Ling Han Yuan-Yuan Chen Lu-Lu Shen Jie Song Josef Vlasák Yu-Cheng Dai Bao-Kai Cui | 2016 | Fungal Diversity2016，，5： | 3 |
| 5 | Penile prosthesis implantation in Chinese patients wit severe erectile dysfunction: 10-year experience显示文摘我们回顾地与严重可勃起的机能障碍(SED ) 在中国病人评估了阴茎修复术培植(PPI ) 的临床的结果。从 2000 年 7 月到 2011 年 12 月, 224 个病人(吝啬的年龄:35.9 ± 11.8 年,变化:20-75 年) 在我们的中心根据标准 PPI 过程由富有经验的外科医生与 SED 经历了 PPI。韧性的修复术(AMS 650 ) 在 45 种情况中被植入(20.1 %) ,并且三片的可膨胀的修复术(AMS 700 CXM 或 AMS 700 CXR ) 在 179 种情况中被植入(79.9 %) 。包括手术后的复杂并发症,临床的功效和夫妇满足,外科的结果被评估在上比手术后地使用医药记录抽象的 6 个月, IIEF-5,生活(QoL ) 的质量分数,和病人 / 搭挡的性满足分数由 Bhojwani 等求婚了。为学习合格的 224 个病人, 201 使遭到(89.7 %) 完成的后续。所有能与吝啬的手术后的 IIEF-5 病人执行性交柱子 PPI, QoL 分数是 20.02 ± 2.32 和 5.28 ± 0.76,分别地它显著地与外科手术前的分数相比被改进(6.29 ± 1.5 和 2.13 ± 0.84, P< 0.01 ) 。201 个人,机械失灵发生在四种情况中(2.0 %) 并且三个盒子被重新植入新设备,和二个盒子(1.0 %) 开发了阴茎的温和弯曲。有感染的阴囊的侵蚀与糖尿病 mellitus 发生在一种情况中(0.5 %) 并且植入的 AMS 的要求的完全的移动 700 CXM。令人满意的性交被 178 个人两次至少每月报导(88.6 %) ,并且对 PPI 外科的全面满足被 89.0 % 报导;人和 82.5 %搭挡。在三片的可膨胀的修复术组的耐心的满足比在韧性的修复术组高(P< 0.05 ) 。然而,在 prostheses 的类型之间,满足没在搭挡调查不同。PPI 是一种安全、有效的治疗选择因为有 SED 和富有经验的外科医生的中国病人根据标准 PPI 执行 PPI 过程能减少 PPI 的手术后的复杂并发症并且能改进耐心的满足比率和 QoL。 | Wei-Dong Song Yi-Ming Yuan Wan-Shou Cui Alex K Wu Yi-Chen Zhu Jing Liu Lin Wang Guang-Yi Ba Jing Peng Zhi-Chao Zhang Bing Gao Ying-Lu Guo Tom F Lue Zhong-Cheng Xin | 2013 | Asian Journal of Andrology2013，15，5： | 3 |
| 6 | Atomic layer deposition enabling higher efficiency solar cells:A review显示文摘Atomic layer deposition(ALD)can synthesise materials with atomic-scale precision.The ability to tune the material composition,film thickness with excellent conformality,allow low-temperature processing,and in-situ real-time monitoring makes this technique very appealing for a wide range of applications.In this review,we focus on the application of ALD layers in a wide range of solar cells.We focus on industrial silicon,thin film,organic and quantum dot solar cells.It is shown that the merits of ALD have already been exploited in a wide range of solar cells at the lab scale and that ALD is already applied in high-volume manufacturing of silicon solar cells. | MdAnower Hossain Kean Thong Khoo Xin Cui Geedhika K Poduval Tian Zhang Xiang Li Wei Min Li Bram Hoex | 2020 | Nano Materials Science2020，2，3： | 3 |
| 7 | In vitro expansion of a multipotent population of human neural progenitor cells显示文摘 | Melissa K Carpenter Xia Cui Zhong-yi HU | 1999 | Exp Neurol1999，158，： | 2 |
| 8 | The role of current limitations in Fowler–Nordheim electron emission from carbon films显示文摘 | Cui J B Teo K B K Tsai J T H | 2000 | Appl Phys Lett2000，77，： | 1 |
| 9 | Effect of matrix composition on the microstructure of in-situ synthesized TiC particulate reinforced ironbased composites 显示文摘 | Mei Z Yan Y W Cui K | 2003 | Materials Letters2003，57，3： | 1 |
| 10 | Responses of saltcedar (Tamarix chinensis) to water table depth and soil salinity in the Yellow River Delta, China显示文摘 | CUI B S YANG Q C ZHANG K J | 2010 | Plant Ecology2010，209，2： | 1 |
| 11 | The HIV/AIDS epidemic in China:history,current strategies and future challenges显示文摘 | Wu Z Rou K Cui H | 2004 | AIDS Education & Prevention2004，16，： | 1 |
| 12 | Spray forming of hypereuteetic A1-Si alloys显示文摘 | CUI C SCHULZ A SCHIMANSKI K ZOCH H W | 2009 | Journal of Materials Processing Technology2009，209，3： | 1 |
| 13 | Expression of neural cell adhe-sion molecule LI in the brain of rats exposed to X-irradiation inutero显示文摘 | Sun X Z Zhang K Cui C | 2003 | J Med Invest2003，50，34： | 1 |
| 14 | Dye Congo Red adsorptive decolorization by adsorbents obtained fi'om Trametes pubescer pellets显示文摘 | Si J Cui B K | 2013 | Desalination and Water Treatment2013，51，： | 1 |
| 15 | Genome - wide distribution of macroH2A1 histone variants in mouse liver chromatin显示文摘 | Changolkar L N Singh G Cui K | 2010 | Molec- ular and Cellular Biology2010，30，23： | 1 |
| 16 | Genetic diversity of wild Au- ricularia auricula-judae revealed by ISSR analysis 显示文摘 | Du P Cui B K Zhang C F | 2013 | Bio- chemical Systematics and Ecology2013，48，： | 1 |
| 17 | Acceptable Warm Ischemia Time of Tracheal Grafts From Non-heart-beating Donors in Rats 显示文摘 | Han JQ Zhang K Cui J | 2011 | Transplantation Proceedings2011，43，10： | 1 |
| 18 | Epidemiologic features and environmental risk factors of severe fever with thrombocytopenia syndrome,Xinyang, China显示文摘 | Liu K Cui N Fang LQ | 2014 | PLoS Negl Trop Dis2014，8，5： | 1 |
| 19 | Phthalate esters(PAEs):Emerging organic contaminants in agricultural soils in peri-urban areas around Guangzhou, China显示文摘 | ZENG F Cui K Y Xie Z Y | 2008 | Environ Pollut2008，156，2： | 1 |
| 20 | High-resolution profiling of histone methylations in the human genome显示文摘 | Cuddapah S Cui K | 2007 | Cell2007，129，4： | 1 |
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