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	题名	作者	年代	出处	被引量
1	一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.	Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P	2014	中华神经外科疾病研究杂志2014，13，5：	6
2	An empirical approach for ranking environmental and energy saving measures in the hotel sector 显示文摘	Beccali M La Gennusa M Lo Coco L	2009	Renewable Energy2009，34，1：	1
3	Heritability of serum resistin and its genetic correlation with insulin resistance-related features in nondiabetic Caucasians显示文摘	Menzaghi C Coco A Salvem ini L	2005	J Clin Endocrinol Metab2005，91，7：	1
4	Treatment of acute respiratory failure secondary to pulmonary edema with bilevel positive airway pressure by nasal mask显示文摘	L O COCO A VITALE G MARCHESE S	1997	Monaldi Arch Chest Dis1997，52，5：	1
5	Genetic Diagnosis and Molecular Monitoring in the Management of Acute Promyelocytic Leukemia显示文摘	Coco F L Diverio D Falini B	1999	Blood1999，94，1：	1
6	An empirical approach for ranking environmental and energy sav- ing measures in the hotel sector显示文摘	Beccali M La Gennusa M Lo Coco L	2009	Renewable Energy2009，34，1：	1
7	A hypothesis accounting for the in- consistent benefit of glucocorticoid therapy in closed head trauma显示文摘	BORSODY M K COCO M L	2001	MedHypotheses2001，56，1：	1
8	Akt2 Gene common allelic variants in insulin resistance and the metabolic syndrome显示文摘	Tassi V Coco A Padovano L		0，，：	1
9	Growth factor engineering by degenerate homoduplex gene family recombination显示文摘	Coco W M Encell L P Levinson W E	2002	Nat Biotechnol2002，20，：	1
10	In vitro Candida albicans biofilm induced proteinase activity and SAP8 expression correlates with in vivo denture stomatitis severity显示文摘	Ramage G Coco B Sherry L	2012	Mycopathologia2012，174，1：	1
11	Determination of lead ( I1 ) and cadmium ( ]I ) in hard and soft wheat by derivative potentiometric stripping analysis 显示文摘	Coco F L Monotti P Fiecchi V	2000	Analyticu Chimica Acta2000，409，1：	1
12	An Empirical Approach for Ranking Environmental and Energy Saving Measures in the Hotel Sector显示文摘	Beccali M Gennusa M L Coco L L Rizzo G	2009	Renewable Energy2009，34，1：	1
13	Duodenocephalopancreatectomy for periampullary neoplasm in elderly patients显示文摘	Antinori A Ciccoritti L Coco C	2005	Suppl Tumori2005，4，3：	1
14	An empirical approach for ranking environmental and energy saving measures in the hotel sector显示文摘	Beccali M La Gennusa M Lo Coco L		0，，：	1
15	Fibroblast growth fac-tor receptor-1is essential for in vitro cardiomyocyte development显示文摘	DELL'ERA P RONCA R COCO L	2003	Circ Res2003，93，5：	1
16	GIMEMA-AIEOP AIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia(APL) in children显示文摘	Testi A M Biondi A Coco F L	2005	Blood2005，106，2：	1
17	Patients requiring interrup?tion of long-term oral anticoagulant therapy: the use of fi xed sub-therapeutic doses of low-molecular-weight heparin显示文摘	Malato A Saccullo G 10 Coco L	2010	J Thromb Haemost2010，8，1：	1
18	Fibroblast growth factor receptor- 1 is essential for in vitro cardiomyocyte development 显示文摘	Ronca R Coco L	2003	Circ Res2003，93，5：	1
19	Determination of cadmium(Ⅱ) and Zinc(Ⅱ) in olive oils by derivative potentiometric stripping analysis显示文摘	Coco F Lo Ceccon L Ciraolo L	2003	Food Control2003，14，：	1
20	Ovulation induction with clomiphene citrate and metformin in women with polycystic ovary syndrome显示文摘	Leanza V Coco L Grasso Fi	2014	Minerva Ginecol2014，66，3：	1

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