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71篇 您的检索式：作者名="Coco B"

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	题名	作者	年代	出处	被引量
1	一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.	Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P	2014	中华神经外科疾病研究杂志2014，13，5：	6
2	Efficacy of caspofungin alone and in combination with voriconazole in guinea pig model of invasive aspergillosis显示文摘	Kirkpatrick W R Perea S Coco B J	2002	Antimicrob Agents Chemother2002，46，：	1
3	Hsp90 (heat shock protein 90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo 显示文摘	TiUotson B Slocum K Coco J	2010	J Biol Chem2010，285，39：	1
4	Hepatitis B surface antigen serum levels help to distinguish active from inactive hepatitis B virus genotype D carriers 显示文摘	Brunetto MR Oliveri F Colombatto P Moriconi F Ciccorossi P Coco B Romagnoli V Cherubini B Moscato G Maina AM Cavallone D Bonino F	2010	Gastroenterology2010，139，2：	1
5	Transient elastography : a new surrogate marker of liver fibrosis influenced by major changes of transaminases 显示文摘	Coco B Oliveri F Maina AM	2007	J Viral Hepat2007，14，5：	1
6	Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia显示文摘	Lo Coco F Diverio D Falini B	1999	Blood1999，94，1：	1
7	Fate of embryonic stem cells transplanted into the deafened mammalian cochlea显示文摘	Coleman B Hardman J Coco A	2006	Cell Transplant2006，15，：	1
8	Transient elastogra-phy:a new surrogate marker of liver fibrosis influenced by-major changes oftransaminases显示文摘	Coco B Oliveri F Maina AM	2007	J Viral Hepat2007，14，5：	1
9	Genetic Diagnosis and Molecular Monitoring in the Management of Acute Promyelocytic Leukemia显示文摘	Coco F L Diverio D Falini B	1999	Blood1999，94，1：	1
10	Outcome of anti - HBe positive chronic hepatitis B in alpha- interferon treated and untreated patients : a long term cohort study 显示文摘	Brunetto MR Oliveri F Coco B	2002	Hepatol2002，36，：	1
11	Fertilizer nitro- gen rates to optimize cotton yield and fiber quality显示文摘	Boquet D J Breitenbeck G A Coco A B	1991	Louisiana Agriculture1991，35，：	1
12	Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients:a long term cohort study显示文摘	Brunetto MR Oliveri F Coco B	2002	Hepatol J2002，36，2：	1
13	Transient elastography:a new surro- gate marker of liver fibrosis influenced by major changes of transaminases显示文摘	Coco B Oliveri F Maina AM	2007	J Viral Hepat2007，14，5：	1
14	Reducing the inci-dence of denture stomatitis: Are denture cleansers suffi-cient显示文摘	Jose A Coco B J Milligan S	2010	J Prosthodont2010，19，4：	1
15	Out come of antiHBe positive chronic hepatitis B in alpha interferon treated and untreated patients:along term cohort study显示文摘	Brunetto MR Oliveri F Coco B	2002	J Hepatol2002，36，：	1
16	In vitro Candida albicans biofilm induced proteinase activity and SAP8 expression correlates with in vivo denture stomatitis severity显示文摘	Ramage G Coco B Sherry L	2012	Mycopathologia2012，174，1：	1
17	Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis显示文摘	Kirkpatrick W R Perea S Coco B J	2002	Antimicrob Agents Chemother2002，46，8：	1
18	Genetic diagnosis and molecular monitoring in the management of acute promyelocytic leukemia显示文摘	Lo Coco F Diverio D Falini B	1999	Blood1999，94，1：	1
19	Transient elastog- raphy:a new surrogate marker of liver fibrosis influenced by major changes of transaminases 显示文摘	COCO B OLIVERI F MAINA A M	2007	J Viral Hepat2007，14，5：	1
20	Transient elastography: a new sur-rogate marker of liver fibrosis influenced by major changes of transami- nases 显示文摘	Coco B Oliveri F Maina AM	2007	J Viral Hepat2007，14，5：	1

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