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| 1 | Emerging role of Hippo pathway in gastric and othergastrointestinal cancers显示文摘More evidence has underscored the importance of Hippo signaling pathway in gastrointestinal tissue homeostasis, whereas its deregulation induces tumorigenesis. Yes-associated protein 1(YAP1) and its close paralog TAZ, transcriptional co-activator with a PDZbinding motif, function as key effectors negatively controlled by the Hippo pathway. YAP1/TAZ exerts oncogenic activities by transcriptional regulation via physical interaction with TEAD transcription factors. In various cancers, Hippo pathway cross-talks with pro- or anti-tumorigenic pathways such as GPCR, Wnt/β-catenin, Notch and TGF-β signaling and is deregulated by multiple factors including cell density/junction and micro RNAs. As YAP1 expression is significantly associated with poor prognosis of gastric and other gastrointestinal cancers, detailed delineation of Hippo regulation in tumorigenesis provides novel insight for therapeutic intervention. In current review, we summarized the recent research progresses on the deregulation of Hippo pathway in the gastrointestinal tract including stomach and discuss the molecular consequences leading to tumorigenesis. | Wei Kang Alfred SL Cheng Jun Yu Ka Fai To | 2016 | World Journal of Gastroenterology2016，22，3： | 11 |
| 2 | Expression of bone matrix protein during dexamethasone-induced mineralization of human bone marrow stromal cell显示文摘 | Cheng SL Zhang SF Avioli LV | 1996 | J Cell Biochem1996，61，2： | 2 |
| 3 | Brain-derived neurotrophic factor and collagen tubulization enhance functional recovery after peripheral nerve transection and repair显示文摘 | Utley DS Lewin SL Cheng ET | 1996 | Arch Otolayngol Head Neck Surg1996，122，4： | 1 |
| 4 | Long-chain SFA at the sn - 1, 3 positions of TAG reduce body fat deposition in C57BL/6 mice 显示文摘 | GoukSW Cheng SF MokJ SL etal | 2013 | British Journal of Nu- trition2013，110，11： | 1 |
| 5 | Cause of axillary bromidrosis 显示文摘 | Mao GY Yang SL Cheng JH | 2009 | Plant ReconstrSurg2009，123，2： | 1 |
| 6 | Rhizosphere priming effects on the decomposition of soil organic matter in C4 and C3 grassland soils显示文摘 | Fu SL Cheng WX | 2002 | Plant and Soil2002，238，2： | 1 |
| 7 | Regulation of alphaVbeta3 and alphaVbeta5 integrins by dexamethasone in normal human osteoblastic cells显示文摘 | Cheng SL Lai CF Fausto A | | 0，，： | 1 |
| 8 | Chronic obstructive pulmonary disease treated with inhaled medium- or nigh-dose corticoteroids: a prospective and randomized study focusing on clinical efficacy and the risk of pneumonia 显示文摘 | Cheng SL Su KC Wang HC | 2014 | Drug Des Devel Ther2014，8，： | 1 |
| 9 | Compliance with home non- invasive ventilation显示文摘 | Cheng SL Chan VL Chu CM | 2012 | Respirology2012，17，4： | 1 |
| 10 | Differentiation of human bone marrow osteogenic stromal cells in vitro:induction of the osteoblast phenotype by dexamethasone显示文摘 | Cheng SL Yang JW Rifas L | 1994 | Endocrinology1994，134，： | 1 |
| 11 | Differential regulation of cadherins by dexamethasone in human osteoblastic cells 显示文摘 | Lecanda F Cheng SL Shin CS | 2000 | J Cell Biochem2000，77，3： | 1 |
| 12 | Rhizosphere effects on decomposition:controls of plant species,phenology,and fertilization显示文摘 | Cheng WX Johnson DW Fu SL | | 0，，： | 1 |
| 13 | Activation of vascular smooth muscle parathyroid hormone receptor inhibits wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis 显示文摘 | Cheng SL Shao JS Halstead LR | 2010 | Circ Res2010，107，2： | 1 |
| 14 | Is the volume of distribution of digoxin reduced in patients with renal dysfunction? Determining digoxin pharmacokinetics by fluorescence polarization immunoassay 显示文摘 | Cheng JW Charland SL Shaw LM | 1997 | Pharmacotherapy1997，17，3： | 1 |
| 15 | Expression of bone matrix proteins during dexamethasone-induced mineralization of human bone marrow stromal cells显示文摘 | Cheng SL Zhang SF Avioli LV | 1996 | J Cell Biochem1996，61，2： | 1 |
| 16 | In vitro and in vivo induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene显示文摘 | Cheng SL Lou J Wright NM | 2001 | Calcif Tissue Int2001，68，2： | 1 |
| 17 | Mutagenesis of varicella-zoster virus glycoprotein I (gI) identifies a cysteine residue critical for gE/gI heterodimer formation, gI structure, and virulence in skin cells 显示文摘 | Oliver SL Sommer MH Reichelt M Rajamani J Vlaycheva-Beisheim L Stamatis S Cheng J Jones C Zehnder J Arvin AM | 2011 | J Virol2011，85，9： | 1 |
| 18 | Factor affecting fetal bradycardia following combined spinal epidural for labor analgesia: a matched case-control study显示文摘 | Cheng SL Bautista D Leo S | 2013 | J Anesth2013，27，2： | 1 |
| 19 | Pivotal factors interfering in 24-hour blood pressure fluctuation and arterial stiffness in a com- munity of Chinese elderly hypertensive patients 显示文摘 | Zang XY Zhang H Cheng SL | 2013 | Journal of Clin- ical Nursing2013，22，34： | 1 |
| 20 | Effect of injection rate of contrast medium on pancreatic and hepatic helical CT显示文摘 | Tublin ME Tessler FN Cheng SL | 1999 | Radiology1999，210，1： | 1 |
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