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| 1 | An equation of entransy transfer and its application显示文摘Entransy is a physical quantity describing heat transfer ability, and heat transfer is accompanied by entransy transfer. Thermal energy is conserved in its transfer process, while entransy is dissipated because of the irreversibility of its transfer process. As a result, entransy transfer must have its rules which are different from those of thermal energy transfer. Based on the definition of entransy, an entransy transfer equation is derived, which describes the entransy transfer processes of a multi-component viscous fluid subject to heat transfer by conduction and convection, mass diffusion and chemical reactions. The expressions of entransy flux and entransy dissipation are obtained simultaneously, and their physical mechanism is clarified. And further, the theory and method of optimizing heat transfer applying the entransy transfer equation to the steady-state convection heat transfer process are expounded. The minimum thermal resistance principle and the entransy dissipation extremum principle are obtained by applying the steady-state entransy transfer equation to the steady-state convection heat transfer process. The cases of the single-component steady-state convection heat transfer and the steady-state heat conduction show the application of the theory and method. | WANG SongPing CHEN QingLin ZHANG BingJian | 2009 | Chinese Science Bulletin2009,54,19: | 23 |
| 2 | Diagnosis of brain death: confirmatory tests after clinical test显示文摘 | Su Yingying Yang Qinglin Liu Gang Zhang Yan Ye Hong Gao Daiquan Zhang Yunzhou Chen Weibi | 2014 | Chinese Medical Journal2014,,7: | 16 |
| 3 | Occurrence and distribution of antibiotic resistance genes in the sediments of the East China Sea bays显示文摘The coastal area of the East China Sea has experienced rapid urbanization and industrialization in China since 1980 s, resulting in severe pollution of its environments.Antibiotic resistance genes(ARGs) are regarded as a kind of emerging pollutant with potential high risk. The sediment samples were collected from Hangzhou Bay(HB),Xiangshan Bay(XB), and Taizhou Bay(TB) to investigate the spatial occurrence and distribution of 27 ARGs and class I integron–integrase gene(intI1) in the coastal area of the East China Sea. The PCR results showed the frequent presence of 11 ARGs and intI1 in the sediments of the three bays. The qPCR results further showed that sulfonamide resistance was the most prevalent ARG type and antibiotic target replacement and protection were the most important resistance mechanisms in the sediments. Regarding the subtype of ARGs, sulI, tetW, and dfrA13 were the most abundant ARGs, in which sulI was higher in TB(based on both the absolute and relative abundances) and dfrA13 was higher in HB(based on the relative abundances). The network analysis revealed that intI1 had significant correlations with tetC, sulI, sulII, and blaPSE-1. Oil was the key connected factor, which had positive connections with sulI, sulII, and blaPSE-1. In addition, the joint effect of heavy metals and nutrients & organic pollutants might be crucial for the fate of ARGs in the coastal sediments. | Jiayu Chen Zhiguo Su Tianjiao Dai Bei Huang Qinglin Mu Yongming Zhang Donghui Wen | 2019 | Journal of Environmental Sciences2019,31,7: | 13 |
| 4 | A general theoretical principle for single-phase convection heat transfer enhancement显示文摘The main methods of single-phase convection heat transfer enhancement are analyzed in this paper, and the unity of contradiction between heat transfer enhancement and energy consumption(or exergy destruction)is expounded.The thermodynamic relationship between heat(or exergy)transfer efficiency and energy consumption(or exergy destruction)as well as driving forces is established,and a general theoretical principle for single-phase convection heat transfer enhancement is further obtained. The principle shows that temperature gradient field distribution and velocity field distribution constrain each other,and that the optimum heat transfer efficiency can be obtained when they are synergetic.If the level of the synergy of temperature gradient field distribution with velocity field distribution is determined,the relative uniform temperature gradient is required,and vice versa.The principle also shows the relationship of relative temperature gradient with specific heat and coefficient of heat conductivity.The deduced results can be used as a theoretical guidance for single-phase convection heat transfer enhancement and optimum design of heat exchangers. | WANG SongPing CHEN QingLin ZHANG BingJian HUA Ben | 2009 | Science China(Technological Sciences)2009,52,12: | 12 |
| 5 | Structure of the receptor-activated human TRPC6 and TRPC3 ion channels显示文摘TRPC6 和 TRPC3 是属于正规短暂受体潜力(TRPC ) 的家庭的激活受体的 nonselective 阳离子隧道隧道。他们被 diacylglycerol 激活,一个类脂化合物秒送信人。TRPC6 和 TRPC3 涉及许多生理的过程并且在人的基因疾病含有。这里我们在场在有最新识别的高亲密关系的禁止者 BTDM 的建筑群的人的 TRPC6 homotetramer 的结构由单个粒子的 cryo 电子显微镜学解决了到 3.8?分辨率。我们也在 4.4 点介绍人的 TRPC3 的结构吗?分辨率。这些结构显示出塑造钟的 cytosolic 层在保持 transmembrane 层的二层的体系结构。包括 N 终端 ankyrin 重复和 C 终端卷卷, cytosolic 领域的广泛的内部子单元的相互作用贡献 tetramer 集会。高亲密关系的禁止者 BTDM 在 S5-S6 毛孔领域和电压之间挤像传感器的领域禁止隧道开。我们的结构揭开 TRPC 隧道的分子的建筑学并且为理解这些隧道的机制提供一个结构的基础。 | Qinglin Tang Wenjun Guo Li Zheng Jing-Xiang Wu Meng Liu Xindi Zhou Xiaolin Zhang Lei Chen | 2018 | Cell Research2018,28,7: | 10 |
| 6 | Infrared radiation characteristics of a hypersonic vehicle under time-varying angles of attack显示文摘Hypersonic vehicles emit strong infrared(IR) radiation signatures that can be treated as a detecting source for object identification and routine diagnosis. This paper is aimed at examining the intrinsic radiation characteristics of a Boost-Glide Vehicle(BGV) under the condition of various Angles of Attack(AOAs). A two-temperature model considering the thermal and chemical nonequilibrium effects is coupled with Navier-Stokes equations solved by the finite volume technique.A gas–solid conjunction heat transfer model is also added into the fluid solver to simulate the surface temperature of the vehicle. The radiative transfer equation is solved with Line of Sight(LOS)algorithm. The computational results for a Hypersonic Technology Vehicle-2(HTV-2) type vehicle show that radiances of the vehicle are strongly dependent on the surface temperature. The presence of AOA results in the significant difference of the surface temperature. Infrared radiation characteristics are also changed in intensity and spectral band due to the AOA. Simulations are performed with two time-varying AOAs. Transient results indicate that the variation of AOA does have a great effect on the infrared radiance and is closely related to observation angle, spectral band, angle size,angular velocity and time history. | Qinglin NIU Zhichao YUAN Biao CHEN Shikui DONG | 2019 | Chinese Journal of Aeronautics2019,32,4: | 10 |
| 7 | Development of welding technique for petrochemical industry in China显示文摘DevelopmentofweldingtechniqueforpetrochemicalindustryinChina¥LIQinglin(Sino-PetrochemicalCorporation,Beijing(100029)ZHOUZhend... | LI Qinglin (Sino-Petrochemical Corporation, Beijing (100029)ZHOU Zhende and CHEN Ke (Sinopec Yanshan Petrochemical Company, Beijing)ZHEN Guorui and ZHANG Youchuan (The Third Construction Company of Sinopec, Beijing) | 1994 | China Welding1994,3,2: | 7 |
| 8 | Suppression of murine breast cancer metastasis by selective inhibition of CXCR4 by synthetic polypeptide derived from viral macrophage inflammatory protein Ⅱ显示文摘Stromal cell-derived factor-1 and its receptor CXC chemokine receptor-4(CXCR4)have been implicated in breast cancer metastasis.A significant association between HER2 and CXCR4 expression has been observed in human breast tumor tissues,and overexpression of CXCR4 is essential for HER2-mediated tumor metastasis.Moreover,CXCR4 expression is low in normal breast tissues and high in malignant tumors,suggesting that a blockade of CXCR4 may limit tumor metastasis.The present study investigated the action of a synthetic antagonist 21-mer peptide derived from viral macrophage inflammatory protein Ⅱ against CXCR4(NT21MP)in inhibiting metastasis in vitro and in vivo.The results showed that chemotaxis of SKBR3 cells toward SDF-1αwas reduced by NT21MP in a dose-dependent manner(P<0.05).NT21MP inhibited tumor growth at 500μg/kg and in combination with Herceptin,the anti-HER2 antibody.The in vivo metastatic assay showed that NT21MP significantly inhibited pulmonary metastasis,and the number of metastatic tumor nodes on the surface of the lung was greatly decreased.Compared with the saline-treated control group,PCNA expression was dose-dependently decreased by NT21MP,the percentage of apoptotic cells was increased,and CXCR4 mRNA and protein expression were downregulated.In conclusion,NT21MP inhibits cellular proliferation,promotes apoptosis by downregulating CXCR4 expression,and suppresses the progression of primary and metastatic tumors.CXCR4 may be a useful therapeutic target for breast cancer,and NT21MP may serve as a potential target drug for the treatment of breast cancer metastasis. | YANG QingLin DING YongXing CHEN ChangJie TANG Jie ZHANG Ju YANG ZhiFeng | 2010 | Chinese Science Bulletin2010,55,20: | 6 |
| 9 | Conservation of Jiaohe ancient earthen site in China显示文摘Earthen sites,which are mainly made of earth,are cultural heritages with historical,artistic and scientific values.Many extremely valuable earthen sites have been preserved in the arid areas in China.The earthen site of Jiaohe Ancient City is one of the earliest National Protected Important Cultural Heritage Sites.The Jiaohe Ancient City site exhibits all kinds of deteriorations,which can be found in the earthen sites in arid environments in China.Through a case study of the Jiaohe ancient earthen site,we present in this paper the comprehensive conservation technologies,including the mud bricklaying and reparation,wooden rod anchorage,crack grouting,surface potassium silicate(PS) penetration consolidation,and suspended steel beam ceiling,etc.Results of this case study showed that better conservation effects could be achieved by selecting proper PS penetration and crack grouting processes based on the deterioration characteristics of the earthen sites.The technology of mud bricklaying and reparation was also an effective method for preventing the earthen body from collapsing.Compared with traditional conservation technologies,the suspended steel beam ceiling technology could effectively reduce the negative impacts to the original state of the earthen site.As for unstable cliffs,a new method using composite anchor rod of bamboo and steel with massive loose earth was applied.Deformation monitoring and temporary supports were critical and indispensable measures for the safe of site conservation projects.Through years of monitoring and practical operation at the Jiaohe ancient earthen site,deterioration at the site has been effectively controlled. | Zuixiong Li Xudong Wang Manli Sun Wenwu Chen Qinglin Guo Huyuan Zhang | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011,3,3: | 6 |
| 10 | High AOA decoupling control for aircraft based on ADRC显示文摘In this paper, a practical decoupling control scheme for fighter aircraft is proposed to achieve high angle of attack(AOA)tracking and super maneuver action by utilizing the thrust vector technology. Firstly, a six degree-of-freedom(DOF) nonlinear model with 12 variables is given. Due to low sufficiency of the aerodynamic actuators at high AOA, a thrust vector model with rotatable engine nozzles is derived. Secondly, the active disturbance rejection control(ADRC) is used to realize a three-channel decoupling control such that a strong coupling between different channels can be treated as total disturbance, which is estimated by the designed extended state observer. The control surface allocation is implemented by the traditional daisy chain method. Finally,the effectiveness of the presented control strategy is demonstrated by some numerical simulation results. | LIU Junjie SUN Mingwei CHEN Zengqiang SUN Qinglin | 2020 | Journal of Systems Engineering and Electronics2020,31,2: | 5 |
| 11 | Efficacy of Lidan Tang on high-fat-diet induced gallstone in mice and possible mechanism显示文摘OBJECTIVE:To investigate efficacy of Lidan Tang(LDT)on gallstone induced by high fat diet in mice,and to study its underlying mechanism.METHODS:Mice were fed with high fat diet every day and treated with LDT(9.01 times of human clinic dosage).Mice were randomly divided into 6 groups as control group,gallstone model group(high-fat diet),positive control ursodeoxycholic acid(UDCA)group(80 mg·kg^-1·d^-1,i.g.),LDT low dose group(6 kg/d,i.g.),LDT middle dose group(12 kg/d,i.g.),and LDT high dose group(24 kg/d,i.g.).The whole experiment was lasted for 4 weeks.The levels of ALT,AST,LDH,CHO,HDL-C and LDL-C in serum were measured,the pathological sections were observed by hematoxylin-eosin staining,the activities of antioxidant enzymes were measured by kits,and the proteins related to oxidative stress and lipid transport were detected by Western blot analysis.RESULTS:LDT could significantly reduce the contents of ALT and AST in serum and improve the pathological tissue of liver.LDT could significantly reduce the content of MDA and LPO,and increase the level of GSH and GSH-PX in liver tissue.The data of Western blot showed that LDT had antioxidant effect promoting Keap1/Nrf2 pathway and regulated the process of lipid transport,which was statistically significant.In addition,LDT treatment inhibited the expression of ATP-binding cassette transports ABCG5/8 in liver,and reduced cholesterol transport from the hepatocytes to the gallbladder.CONCLUSION:LDT has protective effect on gallstones induced by high fat diet in mice,which might be based on the protective effect on liver,including enhancing the antioxidant capacity of liver and reducing the production of lipid peroxides. | Gao Yan Liu Caipin Li Juntong Zhai Yingying Lin Meiyu Wu Qinglin Chu Shifeng Zhang Zhao Li Jianping Zhou Xin Li Yueting Chen Naihong | 2020 | Journal of Traditional Chinese Medicine2020,40,4: | 4 |
| 12 | Transmission of antibiotic resistance genes in agroecosystems: an overview显示文摘The use of antibiotics in human medicine andanimal husbandry has resulted in the continuous release ofantibiotics into the environment, which imposes highselection pressure onbacteria to develop antibioticresistance. The spread and aggregation of antibioticresistance genes (ARGs) in multidrug-resistant pathogensisone of the most intractable clinical challenges.Numerous studies have been conducted to profile thepatterns of ARGS in agricultural ecosystems, as this isclosely related to human health and wellbeing. This paperprovides an overview of the transmission of ARGs inagricultural ecosystems resulting from the application ofanimal manures and other organic amendments. The futureneed to control and mitigate the spread of antibioticresistance in agricultural ecosystems is also discussed,particularly from a holistic perspective, and requiresmultiple sector efforts to translate fundamental knowledgeinto effective strategies. | Jizheng HE Zhenzhen YAN Qinglin CHEN | 2020 | Frontiers of Agricultural Science and Engineering2020,7,3: | 3 |
| 13 | Ir nanoclusters confined within hollow MIL-101(Fe)for selective hydrogenation ofα,β-unsaturated aldehyde显示文摘Although the selective hydrogenation ofα,β-unsaturated aldehyde to unsaturated alcohol(UOL)is an extremely important transformation,it is still a great challenge to achieve high selectivity to UOL due to thermodynamic favoring of the C=C hydrogenation over the C=O hydrogenation.Herein,we report that iridium nanoclusters(Ir NCs)confined within hollow MIL-101(Fe)expresses satisfied reaction activity(93.9%)and high selectivity(96.2%)for the hydrogenation of cinnamaldehyde(CAL)to cinnamyl alcohol(COL)under 1 bar H;atmosphere and room temperature.The unique hollow structure of MIL-101(Fe)benefits for the fast transport of reactant,ensuring the comparable reaction activity and better recyclability of Ir@MIL-101(Fe)than the counterparts which Ir NCs were on the surface of MIL-101(Fe).Furthermore,The X-ray photoelectron spectroscopy data indicates the electropositive Ir NCs,owing to the electron transfer from Ir to MIL-101(Fe),can interact with oxygen lone pairs,and Fourier transform infrared spectrum shows the Lewis acid sites in MIL-101(Fe)can strongly interact with C=O bond,which contributes to a high selectivity for COL.This work suggests the considerable potential of synergetic effect between hollow MOFs and metal nanoclusters for selective hydrogenation reactions. | Qinglin Liu Qian Liu Yurong Chen Yinle Li Hui Su Qinghua Liu Guangqin Li | 2022 | Chinese Chemical Letters2022,33,1: | 3 |
| 14 | Bone-targeting melphalan prodrug with tumor-microenvironment sensitivity: Synthesis, in vitro and in vivo evaluation显示文摘Bone tumor is a refractory neoplastic growth of tissue in bone. According to the unique environment and phys-chemical characteristics of bone tissues, the chemotherapeutic agents are unlikely to prolong the survival of patients and often associated with systemic side effects. The bone targeting drug delivery via systemic administration may provide both better treatment efficacy and less frequent administration. In this study, we describe the synthesis, in vitro and in vivo evaluation of novel melphalan-bisphosphonate hybrids, with a tumor microenvironment sensitive linkage, which could be enzymatic activation under tumor microenvironment conditions. We have also evaluated the in vitro targeting efficiency of these prodrugs via the affinity of hydroxyapatite(HA) and cellular proliferation. The in vivo distribution suggested the bisphosphonate conjugated prodrugs with high bone selectivity. | Can Chen Yiyan Li Xiaoping Yu Qinglin Jiang Xiaohong Xu Qian Yang Zhiyong Qian | 2018 | Chinese Chemical Letters2018,29,11: | 2 |
| 15 | Hot deformation and processing maps of X-750 nickel-based superalloy显示文摘 | Ying Wang Qinglin Pan Yanfang Song Chen Li Zhifeng Li | 2013 | Materials and Design2013,,: | 2 |
| 16 | Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles in rheumatoid arthritis显示文摘Clinical manifestations of rheumatoid arthritis(RA)are diversified,and based on the manifestations,the patients with RA could be classified into different patterns under traditional Chinese medicine.These patterns decide the selection of herbal prescription,and thus they can help find a subset of rheumatoid arthritis patients for a type of therapy.In the present study,we combine genome-wide expression analysis with methods of systems biology to identify the functional gene networks for the sets of clinical symptoms that comprise the major information for pattern classification.Clinical manifestations in rheumatoid arthritis were clustered with factor analysis,and two factors(similar to cold and hot patterns in traditional Chinese medicine)were found.Microarray technology was used to reveal gene expression profiles in CD4^(+)T cells from 21 rheumatoid arthritis patients.Protein-protein interaction information for these genes from databases and literature data was searched.The highly-connected regions were detected to infer significant complexes or pathways in this protein-protein interaction network.The significant pathways and function were extracted from these subnetworks using the Biological Network Gene Ontology tool.The genes significantly related to hot and cold patterns were identified by correlations analysis.MAPK signalling pathway,Wnt signaling pathway,and insulin signaling pathway were found to be related to hot pattern.Purine metabolism was related to both hot and cold patterns.Alanine,aspartate,and tyrosine metabolism were related to cold pattern,and histindine metabolism and lysine degradation were related to hot pattern.The results suggest that cold and hot patterns in traditional Chinese medicine were related to different pathways,and the network analysis might be used for identifying the pattern classification in other diseases. | Miao Jiang Cheng Xiao Gao Chen Cheng Lu Qinglin Zha Xiaoping Yan Weiping Kong Shijie Xu Dahong Ju Pu Xu Youwen Zou Aiping Lu | 2011 | Frontiers of Medicine2011,5,2: | 2 |
| 17 | Runoff and nutrient losses in alfalfa(Medicago sativa L)production with tied-ridge-furrow rainwater harvesting on sloping land显示文摘Ridge-furrow rainwater harvesting(RFRH)is known to be effective in controlling water loss and soil erosion,and increasing soil moisture and crop yield in semiarid regions.However,it can cause water-logging,ridge overtopping,and harvest failure if not properly designed.A four consecutive-year field trial was carried out to assess the impacts of various slope gradients and tillage practices on soil moisture,runoff,sediment yield,associated soil nutrient losses,fodder yield,and water use efficiency(WUE)of alfalfa in the Loess Plateau,China.The trial adopted a split-plot design,taking slope gradient(5and 10)as main plot treatment and tillage practice(traditional tillage,open-ridging,and tied-ridging)as split-plot treatment,from 2015 to 2018.There were greater variations in runoff,sediment yield,and associ-ated soil nutrient losses than in fodder yield and WUE.Tied-ridging and open-ridging resulted in decreased runoff and reduced sediment transport and associated soil nutrient losses,and increased soil moisture,fodder yield,and WUE.Runoff,sediment transport,and associated soil nutrient losses inclined with increasing slope;while fodder yield and the WUE declined.For slopes of 5and 10,the average decrease in runoff,sediment yield,total nitrogen,total phosphorus,and organic matter losses for open-ridging were 47.7e56.2%,91.0e92.7%,90.4e93.1%,90.1e92.2%,and 88.9e90.2%,respectively,while these for tied-ridging were 62.4e68.4%,94.5e96.4%,93.6e95.5%,93.9e95.9%,and 93.0e94.9%,over 4 years as compared with traditional tillage.The mean annual runoff,sediment,total nitrogen,total phosphorus,and organic matter losses for slopes of 10were 1.31,1.96,1.87,1.99,and 1.64 times greater than the corresponding values for slopes of 5,respectively.The increase of fodder yield and WUE for open-ridging and tied-ridging was 40.1e45.6%and 16.0e17.5%,and 3.66e5.99 and 1.35e2.50 kg ha^(-1)mm^(-1),respectively,for slopes of 5and 10.The average fodder yield and WUE for slopes of 5were 1.19 and 1.23 times greater than corresponding values for slopes of 10,respectively.The disparities in fodder yield and WUE of alfalfa between slopes of 5and 10were not clear in dry years,but were evident in wet years.Tied-ridging was recommended for water and soil conservation,while open-ridging was recommended for increase of fodder yield and WUE of alfalfa.The implementation of RFRH in crop production should be evaluated by the use of a model in accordance with climatic conditions,soil type,and plant species. | Qi Wang Fuchun Li Xiaole Zhao Wucheng Zhao Dengkui Zhang Xujiao Zhou David JSample Xiaoyun Wang Qinglin Liu Xiaoling Li Guang Li Heling Wang Kai Zhang Jin Chen | 2022 | International Soil and Water Conservation Research2022,10,2: | 2 |
| 18 | Design and stability analysis of a generalized reduced-order active disturbance rejection controller显示文摘Disturbance and uncertainty rejection is a key objective in control system design, and active disturbance rejection control(ADRC)exactly provides an effective solution to this issue. To this end, this paper presents a generalized active disturbance rejection controller for a class of nonlinear uncertain systems with linear output. To be specific, a generalized reduced-order extended state observer(ESO) is proposed to reduce phase delay and complexity of the system, which can take full advantage of the system output. Also, this method includes the existing results with fewer assumptions, and can be applied to systems with any order measurable states or multiple states, even linear combination states. Furthermore, the stability of this approach is guaranteed and demonstrated through matrix transformation and Lyapunov method, and design examples and numerical simulations are given to show the effectiveness and practicability of the method. | WANG YongShuai CHEN ZengQiang SUN Ming Wei SUN QingLin | 2022 | Science China(Technological Sciences)2022,65,2: | 2 |
| 19 | Effect of Y_2O_3-MgO Addition on Heterogeneous Precipitation-Thermal Reduction Synthesis and Sintering of FeeMo/Si_3N_4 Powders显示文摘Effect of Y2O3e-MgO addition on heterogeneous precipitation-thermal reduction synthesis and the sintering of Fee Mo/Si3N4 powders has been investigated. It was found that the whiskers-like b-Si3N4, good wettability phases on Si3N4 surface, and high toughness Fe phase appeared in Fee Mo/Si3N4 cermets with Y2O3-MgO additives. The results show that Y2O3-MgO additives can effectively optimize the microstructures of Fee Mo/Si3N4 cermets, and improve the material mechanical properties. Therefore, it indicated that Y2O3-MgO additives can be used for strengthening of sintered cermets, and the dual function of whiskers self-toughening and different metal-composition toughening can be achieved in Fee Mo/Si3N4 cermets with Y2O3-MgO additives. | Ruiming Yin Fubao Ji Qinglin Hou Fusheng Liu Jing Li Linzhang Chen | 2014 | Journal of Materials Science & Technology2014,30,3: | 2 |
| 20 | Repairing skull defects in children with nano-hap/collagen composites: A clinical report of thirteen cases显示文摘Objective:To evaluate the clinical results of repairing skull defects with biomimetic bone(nano-hap/collagen composites,NHACs)in children.Methods:Thirteen children with skull defects were treated with NHACs in our hospital.The NHACs molded with the help of a 3D printer were used in the operations.Results:All 13 operations were successful,and patients recovered without infection.Only one patient suffered from subcutaneous hydrops post-operation.The implanted NHACs remained fixed well after 1 year,and their CT HU values raised gradually.Skull shapes of children developed normally.Recovery of neurological and cognitive function was significant.Conclusions:NHAC,chosen to repair skull defects in children,can coexist with normal skull and reduce the negative effects on growth and development.NHAC could be a good choice for children with skull defects. | Tuoyu Chen Yuqi Zhang Huancong Zuo Yapeng Zhao Chaoqiang Xue Bin Luo Qinglin Zhang Jin Zhu Xiumei Wang Fuzhai Cui | 2016 | Translational Neuroscience and Clinics2016,2,1: | 2 |