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| 1 | Radiofrequency ablation for treatment of hypersplenism: A feasible therapeutic option显示文摘We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. We performed spleen ablation and measured the total spleen and ablated volumes with contrast-enhanced computed tomography and volumetry. No major complications occurred, thrombocytopenia was resolved, and platelet levels remained stable, which allowed for early treatment of the patient's underlying disease. Previous work has shown that splenic radiofrequency ablation is an attractive alternative treatment for hypersplenism induced by liver cirrhosis. We aimed to contribute to the currently sparse literature evaluating the role of radiofrequency ablation(RFA) in the management of hypersplenism. We conclude that splenic RFA appears to be a viable and promising option for the treatment of hypersplenism. | Guilherme Lopes P Martins Joao Paulo G Bernardes Marcello S Rovella Raphael G Andrade Publio Cesar C Viana Paulo Herman Giovanni Guido Cerri Marcos Roberto Menezes | 2015 | World Journal of Gastroenterology2015，21，20： | 17 |
| 2 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Combined targeted therapies in non - small cell lung cancer: a winner strategy? 显示文摘 | TINA C CESARE G FORTUNATO C | 2007 | Curr Opin Oncol2007，19，2： | 1 |
| 5 | Robust Array Beamforming with Sidelobe Control Using Support Vector Machines 显示文摘 | Cesar C G Ignacio S Javier V | 2007 | IEEE Trans on Signal Processing2007，55，2： | 1 |
| 6 | Breastfeeding and school achievement in Brazilian adolescents显示文摘 | Cesar G Fernando C Bernardo L | 2005 | Acta Paediatr2005，94，： | 1 |
| 7 | Robust array beam- forming wit h sidelobe cont rolusing support vector machines 显示文摘 | Cesar C G Ignacio S J avier V | 2007 | IEEE Transactions on Signal Processing2007，55，2： | 1 |
| 8 | Spark plasma sintering of Ti x Ta 1? x C 0.5 N 0.5 -based cermets: Effects of processing conditions on chemistry, microstructure and mechanical properties显示文摘 | José M. Córdoba Ernesto Chicardi Rosalía Poyato Francisco J. Gotor Valentina Medri Stefano Guicciardi Cesare Melandri | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 9 | Virtual laboratory for planetary materials: System service architecture overview显示文摘 | CESAR R S PEDRO R C BIJAYA K | 2007 | Physics of the Earth and Planetary Interiors2007，163，8： | 1 |
| 10 | Training pharmacy workers in recognition,management,and prevention of STDs:district-randomized controlled trial显示文摘 | PATRICIA G JAMES H CESAR C | 2003 | Bull WHO2003，81，11： | 1 |
| 11 | Biochemical properties and barley yield in a semia rid Mediterr anean soil a-mended with two kinds of sewage sludge显示文摘 | Fernandez J M Cesar P Juan C | 2009 | Appied Soil Ecology2009，，42： | 1 |
| 12 | Variable epitope library-based vaccines:shooting moving targets显示文摘 | CESAR P R CLAUDIA C N RAFAEL S | 2009 | Molecular Immunology2009，47，2： | 1 |
| 13 | Robust Array Beamforming with Sidelobe Control Using Support Vector Machines 显示文摘 | Cesar C Gandes Javier Via Ignacio Santamaria | 2007 | IEEE Transactions on Signal Processing2007，55，2： | 1 |
| 14 | Organizational innovation as an enabler of technological innovation capabilities and firm performance 显示文摘 | CESAR C ANA V | 2014 | Journal of Business Research2014，67，1： | 1 |
| 15 | Influence of the operating conditions on highly oxidative radicals generation in Fcnton's systems显示文摘 | Cesare C Renato B Tuula T | 2009 | Journal of Hazardous Materials2009，16，1： | 1 |
| 16 | Sources of cardiomyocytes for stem cell therapy:an update显示文摘 | Pasquale G Cesare P Gianluigi C | 2006 | Pediatric Res2006，59，4： | 1 |
| 17 | Knowledge Creation and Absorptive Capacity= The Effect of Intra-Distriet Shared Competences 显示文摘 | CESAR C BEATRIZ F | 2011 | Scandinavian Journal o{ Management2011，27，1： | 1 |
| 18 | p95-APPl links membranetransport to Rac-mediated reorganization of actin显示文摘 | Di Cesare A Paris S Albertinazzi C | 2000 | Nat Cell Biol2000，2，8： | 1 |
| 19 | Cardiopulmonary responses to exercise in patients of different age group with conges tive heart failure显示文摘 | Cesar Mde C Montesano F T Diniz R V | 2006 | Arq Bras Cardiol2006，86，1： | 1 |
| 20 | Docking and quantum mechanic studies on chlolinesterases and their inhibitiors 显示文摘 | Jose C B Cesar F S Jesus M C | 2007 | Eur J Medicinal Chem2007，42，1： | 1 |
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