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| 1 | Hydrogen sulfide, a signaling molecule in plant stress responses显示文摘Gaseous molecules, such as hydrogen sulfide(H_2S)and nitric oxide(NO), are crucial players in cellular and(patho)physiological processes in biological systems. The biological functions of these gaseous molecules, which were first discovered and identified as gasotransmitters in animals, have received unprecedented attention from plant scientists in recent decades. Researchers have arrived at the consensus that H_2S is synthesized endogenously and serves as a signaling molecule throughout the plant life cycle.However, the mechanisms of H_2S action in redox biology is still largely unexplored. This review highlights what we currently know about the characteristics and biosynthesis of H_2S in plants. Additionally,we summarize the role of H_2S in plant resistance to abiotic stress. Moreover, we propose and discuss possible redox-dependent mechanisms by which H_2S regulates plant physiology. | Jing Zhang Mingjian Zhou Heng Zhou Didi Zhao Cecilia Gotor Luis CRomero Jie Shen Zhenglin Ge Zhirong Zhang Wenbiao Shen Xingxing Yuan Yanjie Xie | 2021 | Journal of Integrative Plant Biology2021，63，1： | 8 |
| 2 | Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis显示文摘Hydrogen sulfide(H2S)is a signaling molecule that regulates plant hormone and stress responses.The phytohormone abscisic acid(ABA)plays an important role in plant adaptation to unfavorable environmental conditions and induces the persulfidation of L-CYSTEINE DESULFHYDRASE1(DES1)and the production of H2S in guard cells.However,it remains largely unclear how H2S and protein persulfidation participate in the relay of ABA signals.In this study,we discovered that ABSCISIC ACID INSENSITIVE 4(ABI4)acts downstream of DES1 in the control of ABA responses in Arabidopsis.ABI4 undergoes persulfidation at Cys250 that is triggered in a time-dependent manner by ABA,and loss of DES1 function impairs this process.Cys250 and its persulfidation are essential for ABI4 function in the regulation of plant responses to ABA and the H2S donor NaHS during germination,seedling establishment,and stomatal closure,which are abolished in the ABI4Cys250Ala mutated variant.Introduction of the ABI4Cys250Ala variant into the abi4 des1 mutant did not rescue its hyposensitivity to ABA.Cys250 is critical for the binding of ABI4 to its cognate motif in the promoter of Mitogen-Activated Protein Kinase Kinase Kinase 18(MAPKKK18),which propagates the MAPK signaling cascade induced by ABA.Furthermore,the DES1-mediated persulfidation of ABI4 enhances the transactivation activity of ABI4 toward MAPKKK18,and ABI4 can bind the DES1 promoter,forming a regulatory loop.Taken together,these findings advance our understanding of a post-translational regulatory mechanism and suggest that ABI4 functions as an integrator of ABA and MAPK signals through a process in which DES1-produced H2S persulfidates ABI4 at Cys250. | Mingjian Zhou Jing Zhang Jie Shen Heng Zhou Didi Zhao Cecilia Gotor Luis CRomero Ling Fu Zongmin Li Jing Yang Wenbiao Shen Xingxing Yuan Yanjie Xie | 2021 | Molecular Plant2021，14，6： | 5 |
| 3 | Mitochondrial Sulfide Detoxification Requires a Functional Isoform O-Acetylserine(thiol)lyase C in Arabidopsis thaliana显示文摘在 non-cyanogenic 种类,氰化物的主要来源源于乙烯和 camalexin biosyntheses。在线粒体,氰化物是细胞色素 c oxidase 的一个有势力禁止者并且被 -cyanoalanine synthase CYS-C1 使产生代射变化,催化到氢硫化物和 -cyanoalanine 的半胱氨酸和氰化物的变换。释放的氢硫化物也禁止细胞色素 c oxidase 并且需要被 O-acetylserine (thiol ) lyase mitochondrial isoform 除去, OAS-C,催化硫化物的加入到 O-acetylserine 生产半胱氨酸,因此在线粒体产生一条周期的小径。功能的 OAS-C isoforms 的损失引起 phenotypic 很类似于 CYS-C1 酶的损失的特征,显示出在根头发形成的缺点。有 OAS-C 基因的基因互补救根头发延伸的缺陷,恢复野类型的显型。线粒体妥协他们适当地除去的能力氰化物和产生硫化物因为后者不能在 oas-c 0 异种重新吸收进半胱氨酸。因而,我们观察硫化物和氰化物并且其他的 oxidase 的累积,它是不能的由于两个有毒的分子的累积可能阻止反应的氧种类的生产。我们的结果允许我们建议 OAS-C 的意义在线粒体与它在合适的硫化物和氰化物 detoxification 的角色有关。 | Consolacien Alvarez Irene Garcia Luis C Romero Cecilia Gotor | 2012 | Molecular Plant2012，5，6： | 2 |
| 4 | Chemoenzymatic preparation of optically active seeondary amines: A new efficient route to enantiomeritally pure indulines 显示文摘 | Gotor-Femandez V Femandez-Torres P Gotor V | 2006 | Tetrahcdron: Asymmetry2006，17，： | 1 |
| 5 | Spark plasma sintering of Ti x Ta 1? x C 0.5 N 0.5 -based cermets: Effects of processing conditions on chemistry, microstructure and mechanical properties显示文摘 | José M. Córdoba Ernesto Chicardi Rosalía Poyato Francisco J. Gotor Valentina Medri Stefano Guicciardi Cesare Melandri | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 6 | Regioselective and stereospecific synthesis of enantiopure 1,3-oxazolidin- 2-ones by intramolecular ring opening of 2- (Bocarninomethyl) aziridines, preparation of the antibiotic linezolid 显示文摘 | Moran-Ramallal R Liz R Gotor V | 2008 | Org Lett2008，10，10： | 1 |
| 7 | 显示文摘 | Gotor F J Perez-Maqueda L A Criado J M | 2003 | J Eur Ceram Soc2003，23，： | 1 |
| 8 | Kinetic analysis of solidstate reactions: The university of master plots for analyzing isothermal and non-isothermal experiments显示文摘 | Gotor F J Criado J M Malek J | 2000 | Journal of Physical Chemistry : Part A2000，104，10： | 1 |
| 9 | Lipases : Useful biocatalysts for the preparation of pharmaceuticals 显示文摘 | Gotor-Fernandez V Brieva R Gotor V | 2006 | J Mol Catalysis B : Enzymatic2006，40，： | 1 |
| 10 | Chemoenzymatic syntheses of polyamines and teraazamacrocycles显示文摘 | Rubi M Astorga C Gotor V | 2002 | Synth Commun2002，32，： | 1 |
| 11 | Aggregate size distribution evolution for Brownian coagulation-sensitivity to an improved rate constant 显示文摘 | GOTOR M Z ROSNER D E | 2004 | Journal of Colloid and Interface Science2004，274，： | 1 |
| 12 | Biocatalysis applied to the preparation of phar- maceuticals显示文摘 | Gotor V | 2002 | Organic Process Research & Development2002，6，4： | 1 |
| 13 | Lipases: Useful biocatalysts for the preparation of pharmaceuticals显示文摘 | Gotor-Fernandez V Brieva R Gotor V | 2006 | Journal of Molecular Catalysis B: Enzymatic2006，40，34： | 1 |
| 14 | Enantioselective enzymatic desymmetrizations in organic synthesis显示文摘 | Alfonso I Gotor V | 2005 | Chem Rev2005，105，： | 1 |
| 15 | Selective aminoacylation of nucleosides through an enzymatic reaction with oxime aminocyl esters 显示文摘 | Moris F Gotor V | 1994 | Tetrahedron1994，50，23： | 1 |
| 16 | Bioeatalytic and biomimetie aminolysis reactions: Useful tools for selective transformations on polyfunctional substrates显示文摘 | Alfonso I Gotor V | 2004 | Chemieal Society Reviews2004，33，4： | 1 |
| 17 | Biocatalytic and biomimetic aminolysis reactions:useful tools for selective transformations on polyfunctional substrates显示文摘 | ALFONSO I GOTOR V | 2004 | Chem Soc Rev2004，33，4： | 1 |
| 18 | Isolation and analysis of the soybean SGA2 gene(cDNA),encoding a new member of the plant G-protein family of signal transducers显示文摘 | | 1996 | Plant Mol Biol1996，32，： | 1 |
| 19 | Chemoenzymatic preparation of optically active secondary amines : a new efficient route to enantiomerically pure indulines 显示文摘 | Gotor-Fernandez V Fernandez-Torres P Gotor V | 2006 | Tetrahedron: Asymmetry2006，17，： | 1 |
| 20 | Lipase-catalyzed transesterification in organic media:solvent effects on equilibrium and individuals rate constants显示文摘 | GARCIA-ALLES L F GOTOR V | 1998 | Biotech and Bioeng1998，59，： | 1 |
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