|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis显示文摘AIM: To investigate the single nucleotide polymorphisms (SNPs) in genes involved in bacterial recognition and the susceptibility to pouchitis or pouchitis severity.METHODS: Analyses of CD14 -260C>T, CARD15/NOD2 3020insC, Toll-like receptor (TLR)4 +896A>G,TLR9 -1237T>C, TLR9+ 2848G>A, and IRAKM +22148G>A SNPs were performed in 157 ileal-pouch anal anastomosis (IPAA) patients (79 patients who did not develop pouchitis, 43 infrequent pouchitis patients,35 chronic relapsing pouchitis patients) and 224 Italian Caucasian healthy controls.RESULTS: No significant differences were found in SNP frequencies between controls and IPAA patients.However, a significant difference in carriership frequency of the TLR9-1237C allele was found between the infrequent pouchitis and chronic relapsing pouchitis groups [P = 0.028, odd's ratio (OR) = 3.2, 95%CI = 1.2-8.6].This allele uniquely represented a 4-locus TLR9 haplotype comprising both studied TLR9 SNPs in Caucasians.Carrier trait analysis revealed an enhanced combined carriership of the alleles TLR9 -1237C and CD14 -260T in the chronic relapsing pouchitis and infrequent pouchitis group (P = 0.018, OR = 4.1, 95%CI = 1.4 -12.3).CONCLUSION: There is no evidence that the SNPs predispose to the need for IPAA surgery. The significant increase of the combined carriership of the CD14 -260T and TLR9 -1237C alleles in the chronic relapsing pouchitis group suggests that these markers identify a subgroup of IPAA patients with a risk of developing chronic or refractory pouchitis. | KM Lammers S Ouburg SA Morré JBA Crusius P Gionchetti F Rizzello C Morselli E Caramelli R Conte G Poggioli M Campieri AS Pea | 2005 | World Journal of Gastroenterology2005，11，46： | 7 |
| 2 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，3： | 1 |
| 3 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concen- tration显示文摘 | CAMPIERI C CAMPIERI M BERTUZZI V | 2001 | Kidney Int2001，60，3： | 1 |
| 4 | Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease显示文摘 | Belluzzi A Brignola C Campieri M | 1996 | N Engl J Med1996，334，24： | 1 |
| 5 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，3： | 1 |
| 6 | Treatment of ulcerative colitis with high-dose 5-aminosalicyclic acid enemas显示文摘 | Campieri M Lanfranchi GA Bazzocchi G Brignola C Sarti F Franzin G Battocchia A Labo G Dal MontePR | 1981 | Lancet1981，45，8： | 1 |
| 7 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，： | 1 |
| 8 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V et aI | 2001 | Kidney Int2001，60，3： | 1 |
| 9 | Optimun dosage of 5-aminoalicyclic acid as rectal enemas in patient with active ulcerative colitis显示文摘 | Campieri M Gionchetti P Benizzi A Brigola C Tampieri M Lannone P Miglioli M Barbara L | 1991 | Gut1991，32，8： | 1 |
| 10 | Effect of an enteric- coated fish-oil preparation on relapses in Crohn's disease显示文摘 | Belluzzi A Brignola C Campieri M | 1996 | N Engl J Med1996，334，24： | 1 |
| 11 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration 显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney international2001，60，3： | 1 |
| 12 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，3： | 1 |
| 13 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，3： | 1 |
| 14 | Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease显示文摘 | Belluzzi A Brignola C Campieri M | 1996 | N Engl J Med1996，334，： | 1 |
| 15 | Scavenger Effect of Sulfasalazine,5-Aminosalicylic Acid,and Olsalazine on Superoxide Radical Generation显示文摘 | Gionchette P Guarnieri C Campieri M | | 0，，02： | 1 |
| 16 | Reduction of oxaluria after an oral comse of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，3： | 1 |
| 17 | Effect of an enteric-coated fish-oil preparation on relapses in crohn's disease显示文摘 | Belluzzi A Brignola C 'Campieri M | 1996 | N Engl J Med1996，334，24： | 1 |
| 18 | 3R study:Renal ischemia:Revascularisation or medical treatment显示文摘 | Zuccala A Zucchelli P Campieri C | 2000 | J Nephrol2000，13，： | 1 |
| 19 | Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration显示文摘 | Campieri C Campieri M Bertuzzi V | 2001 | Kidney Int2001，60，3： | 1 |
| 20 | Reduction of oxalufia after an oral course of lactic acid bacteria at high concentration显示文摘 | CAMPIERI C CAMPIERI M BERTUZZI V | 2001 | Kidney Int2001，60，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员