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| 1 | Immune regulatory properties of multipotent mesenchymal stromal cells:Where do we stand?显示文摘Multipotent mesenchymal stromal cells (MSC) can be isolated and efficiently expanded from almost every single body tissue and have the ability of self-renewal and differentiation into various mesodermal cell lineages. Moreover, these cells are considered immunologically privileged, related to a lack of surface expression of costimulatory molecules required for complete T cell activation. Recently, it has been observed that MSC are capable of suppressing the immune response by inhibiting the maturation of dendritic cells and suppressing the function of T lymphocytes, B lymphocytes and natural killer cells in autoimmune and inflammatory diseases as a new strategy for immunosuppression. The understanding of immune regulation mechanisms by MSC is necessary for their use as immunotherapy in clinical applications for several diseases. | ênio José Bassi Carlos Alberto Mayora Aita Niels Olsen Saraiva Camara | 2011 | World Journal of Stem Cells2011，3，1： | 27 |
| 2 | Innate lymphoid cells in tissue homeostasis and diseases显示文摘Innate lymphoid cells(ILCs) are the most recently discovered family of innate immune cells. They are a part of the innate immune system, but develop from the lymphoid lineage. They lack pattern-recognition receptors and rearranged receptors, and therefore cannot directly mediate antigen specific responses. The progenitors specifically associated with the ILCs lineage have been uncovered, enabling the distinction between ILCs and natural killer cells. Based on the requirement of specific transcription factors and their patterns of cytokine production, ILCs are categorized into three subsets(ILC1, ILC2 and ILC3). First observed in mucosal surfaces, these cell populations interact with hematopoietic and non-hematopoietic cells throughout the body during homeostasis and diseases, promoting immunity, commensal microbiota tolerance, tissue repair and inflammation. Over the last 8 years, ILCs came into the spotlight as an essential cell type able to integrate diverse host immune responses. Recently, it became known that ILC subsets play a key role in immune responses at barrier surfaces, interacting with the microbiota, nutrients and metabolites. Since the liver receives the venous blood directly from the intestinal vein, the intestine and liver are essential to maintain tolerance and can rapidly respond to infections or tissue damage. Therefore, in this review, we discuss recent findings regarding ILC functions in homeostasis and disease, with a focus on the intestine and liver. | Aline Ignacio Cristiane Naffah Souza Breda Niels Olsen Saraiva Camara | 2017 | World Journal of Hepatology2017，9，23： | 12 |
| 3 | 秦岭大熊猫自然保护区与社区发展中的问题与对策——以长青自然保护区为例显示文摘在分析陕西秦岭大熊猫自然保护区发展现状的基础上,对其建设管理与周边社区经济社会中存在的问题进行了分析,探讨了自然保护区与周边社区的相互影响关系,提出了大熊猫自然保护区与社区协调发展的对策建议。 | 王昌海 温亚利 时鉴 CAMARA MOUSSA | 2011 | 资源开发与市场2011，27，2： | 9 |
| 4 | Impact of land uses on water quality in Malaysia: a review显示文摘Land use changes in urbanization,industrialization,and agricultural processes will continue to have negative impacts on water quality at all scales.The impact of land use changes on water quality is generally studied by analyzing the relationships between land use and water quality indicators.Therefore,the purpose of this research was to review and analyze the main relationships between land use and water quality,as well as to visualize the major sources and processes of water quality pollution in Malaysia.To achieve our goal,we evaluated the significance of both land use and water quality attributes used in the past studies and correlated them to understand their relationship from another angle of view.The results revealed that 87%of the reviewed studies indicated urban land use as a major source of water pollution,while 82%indicated agricultural land use,77%indicated forest land use,and 44%indicated other land uses.However,the results of correlation analysis showed that agricultural and forest-related activities more affected water quality through their significant positive correlation with physical and chemical indicators of water quality,while urban development activities had a greater impact on water quality through altering hydrological processes such as runoff and erosion.These findings would provide decision-makers with useful information for managing water pollution processes rather than sources only. | Moriken Camara Nor Rohaizah Jamil Ahmad Fikri Bin Abdullah | 2019 | Ecological Processes2019，8，1： | 8 |
| 5 | Obesity in kidney disease:A heavyweight opponen显示文摘Obesity is an important worldwide challenge that must be faced in most developed and developing countries because of unhealthy nutritional habits.The consequences of obesity and being overweight are observed in different organs,but the kidney is one of the most affected.Excess adipose tissue causes hemodynamic alterations in the kidney that can result in renal disease.However,obesity is also commonly associated with other comorbidities such as chronic inflammation,hypertension and diabetes.This association of several aggravating factors is still a matter of concern in clinical and basic research because the pathophysiologic mechanisms surrounding chronic kidney disease development in obese patients remain unclear.This review will discuss the consequences of obesity in the context of renal injury. | Raphael Jose Ferreira Felizardo Marina Burgos da Silva Cristhiane Favero Aguiar Niels Olsen Saraiva Camara | 2014 | World Journal of Nephrology2014，3，3： | 7 |
| 6 | 血吸虫性膀胱炎的CT表现显示文摘目的 探讨血吸虫性膀胱炎的CT表现.方法 回顾性分析32例经尿液细胞学检查找到虫卵证实的32例血吸虫性膀胱炎患者资料,所有患者均行CT平扫加增强扫描,观察病变累及部位和膀胱壁、输尿管等表现,并观察膀胱充盈及排空后的大小变化.结果 32例CT上均见膀胱壁蛋壳样或弧形钙化,增强后膀胱壁未钙化区轻度强化.除5例合并膀胱癌外,其余患者膀胱充盈及排空后大小变化基本正常.25例伴输尿管下段钙化,22例伴输尿管肾盂积水.11例男性患者中有4例可见精囊钙化.女性患者的子宫、卵巢和男性患者的前列腺均未见钙化.5例合并膀胱癌,膀胱壁明显不规则增厚,增强后中度强化.结论 膀胱钙化是血吸虫性膀胱炎最典型的CT表现,有助于该病的诊断. | 王宇军 胡利荣 程有根 茅国群 杨光钊 Modya Camara Mohamed Traore | 2014 | 中华放射学杂志2014，48，2： | 4 |
| 7 | Effect of Ovariectomy on Serum Adiponectin Levels and Visceral Fat in Rats显示文摘This study was aimed to examine the effect of ovariectomy on visceral fat, serum adiponectin levels and lipid profile. Forty-five female Sprague Dawley rats were divided into three groups(n=15 each): ovariectomized group(OVX), ovariectomized plus estrogen-treated group(OVX+E2), and sham-operated group(SHAM). Body weight, abdominal adipose tissues, serum adiponectin and lipid profile were measured and compared among the groups after three-month feeding post-surgery. Significant increases in body weight and visceral fat were found in ovariectomized rats when compared with sham-operated ones and significant increases were also observed in serum adiponectin, triglyceride and very low density lipoprotein cholesterol levels in ovariectomized rats. Body weight, visceral fat and serum adiponectin levels were profoundly reduced in OVX+E2 group as compared with OVX group. It was concluded that ovarian hormone deficiency induced by ovariectomy leads to significant increases in body weight and visceral fat, along with increased serum adiponectin, triglyceride and very low density lipoprotein cholesterol levels in rats. Attenuation in these changes can be achieved by estrogen supplementation. | Camara Ce 周林远 马炎 朱琳 于东 赵要武 杨年红 | 2014 | Journal of Huazhong University of Science and Technology(Medical Sciences)2014，34，6： | 4 |
| 8 | 区域地下水持续开发利用的风险分析研究显示文摘根据区域水源情况由于各地区的地形、地质、水文地质等条件存在差异,以及区域地下水资源开发利用规划管理特点不同,决定了它存在一定程度的不确定性和不准确因素的情况,探讨了区域地下水开发利用的可持续性理念,以及造成不可持续的原因及其后果,并提出了进行地下水不可持续的风险定量分析的可行方案. | Alkaly Camara 朱元甡 束龙仓 施鑫源 | 2003 | 河海大学学报(自然科学版)2003，31，4： | 3 |
| 9 | High Risk Factors of Pancreatic Carcinoma显示文摘Over the past decades, cancer has become one of the toughest challenges for health professionals. The epidemiologists are increasingly directing their research efforts on various malignant tumor worldwide. Of note, incidence of cancers is on the rise more quickly in developed countries. Indeed, great endeavors have to be made in the control of the life-threatening disease. As we know it, pancreatic cancer(PC) is a malignant disease with the worst prognosis. While little is known about the etiology of the PC and measures to prevent the condition, so far, a number of risk factors have been identified. Genetic factors, pre-malignant lesions, predisposing diseases and exogenous factors have been found to be linked to PC. Genetic susceptibility was observed in 10% of PC cases, including inherited PC syndromes and familial PC. However, in the remaining 90%, their PC might be caused by genetic factors in combination with environmental factors. Nonetheless, the exact mechanism of the two kinds of factors, endogenous and exogenous, working together to cause PC remains poorly understood. The fact that most pancreatic neoplasms are diagnosed at an incurable stage of the disease highlights the need to identify risk factors and to understand their contribution to carcinogenesis. This article reviews the high risk factors contributing to the development of PC, to provide information for clinicians and epidemiologists. | Soriba Naby Camara 殷涛 杨明 李响 龚琼 周静 赵刚 杨智勇 Tajoo Aroun Martin Kuete Sonam Ramdany Alpha Kabinet Camara Aissatou Taran Diallo 冯珍 宁辛 熊炯新 陶京 钦琪 周伟 崔静 黄敏 郭尧 勾善淼 王博 刘涛 Ohoya Etsaka Terence Olivier Tenin Conde Mohamed Cisse Aboubacar Sidiki Magassouba Sneha Ballah Naby Laye Moussa Keita Ibrahima Sory Souare Aboubacar Toure Sadamoudou Traore Abdoulaye Korse Balde Namory Keita Naby Daouda Camara Dusabe Emmanuel 吴河水 王春友 | 2016 | Journal of Huazhong University of Science and Technology(Medical Sciences)2016，36，3： | 3 |
| 10 | Biological activities of sulfated polysaccharides from tropical seaweeds显示文摘 | L.S. Costa G.P. Fidelis S.L. Cordeiro R.M. Oliveira D.A. Sabry R.B.G. Camara L.T.D.B. Nobre M.S.S.P. Costa J. Almeida-Lima E.H.C. Farias E.L. Leite H.A.O. Rocha | 2009 | Biomedicine & Pharmacotherapy2009，，1： | 3 |
| 11 | Role of aryl hydrocarbon receptor in mesenchymal stromal cell activation:A minireview显示文摘Mesenchymal stromal cells(MSCs) possess great therapeutic advantages due to their ability to produce a diverse array of trophic/growth factors related to cytoprotection and immunoregulation.MSC activation via specific receptors is a crucial event for these cells to exert their immunosuppressive response.The aryl-hydrocarbon receptor(Ah R) is a sensitive molecule for external signals and it is expressed in MSCs and,upon positive activation,may potentially regulate the MSC-associated immunomodulatory function.Consequently,signalling pathways linked to Ah R activation can elucidate some of the molecular cascades involved in MSC-mediated immunosuppression.In this minireview,we have noted some important findings concerning MSC regulation via Ah R,highlighting that its activation is associated with improvement in migration and immunoregulation,as well as an increase in pro-regenerative potential.Thus,Ah R-mediated MSC activation can contribute to new perspectives on MSC-based therapies,particularly those directed at immune-associated disorders. | Danilo Candido de Almeida Laura Sibele Martins Evangelista Niels Olsen Saraiva Camara | 2017 | World Journal of Stem Cells2017，9，9： | 2 |
| 12 | 耦合反应器中化学链燃烧的模拟显示文摘基于颗粒动理学和化学动力学理论,建立化学链燃烧计算模型,数值模拟了耦合反应器内化学链燃烧过程,获得了反应器内流场特性和各组分分布规律,并很好地捕捉到了空气反应器中颗粒呈现出的非均匀环核流动结构。模拟结果同时给出了反应器中温度分布规律以及各出口颗粒质量流率和各组分浓度随时间的变化,为耦合反应器的设计优化提供了一定的依据。 | M'BOUNANA Noé-Landry-Privace 王帅 杨运超 CAMARA Namory 陆慧林 | 2014 | 工程热物理学报2014，35，7： | 2 |
| 13 | Optimization of room-and-pillar dimensions using automated numerical models显示文摘This paper presents an optimization methodology for the geometric configuration of a room–and–pillar mining project,considering safety and operational restrictions while maximizing ore recovery.An underground manganese mine was chosen as a case study to investigate the capabilities of the presented methodology.A software package(OPTIMINE)was implemented to address the computational demand in an automated manner.Three–dimensional finite difference analyses were performed in FLAC3D and used as implicit functions to consider safety in terms of the factor of safety and room convergence.The obtained results showed that recovery could be increased from 44%to more than 80%in a safe manner. | Gian Franco Napa-García Tais Renata Camara Vidal Félix Navarro Torres | 2019 | International Journal of Mining Science and Technology2019，29，5： | 2 |
| 14 | Ultrastructural Aspects of Cooled Thermal Injury显示文摘 | DONNA L. de CAMARA TALMAGE RAINE MARTIN C. ROBSON | 1981 | The Journal of Trauma: Injury Infection and Critical Care1981，，11： | 2 |
| 15 | 高浓度颗粒气固两相流动的二阶矩模型的数值模拟显示文摘采用动理学方法,用各向异性的M axwell颗粒速度分布函数,建立颗粒相Boltzm ann方程,分别取零次矩、一次矩和二次矩得到颗粒相连续方程、动量方程和二阶矩方程.模拟计算得到上升管内颗粒流场分布和脉动速度分布,与实验结果比较表明:各向异性颗粒动理学能够反映颗粒流动特性,从而能够更全面地认识高颗粒浓度气固两相流动过程. | Namory Camara 陆慧林 赵云华 刘文铁 李响 | 2006 | 哈尔滨工业大学学报2006，38，11： | 2 |
| 16 | The capsanthin-capsorubin synthase gene: a candidate gene for the y locus controlling the red fruit colour in pepper显示文摘 | Véronique Lefebvre Marcel Kuntz Bilal Camara Alain Palloix | 1998 | Plant Molecular Biology1998，，5： | 2 |
| 17 | Etiology, Pathology, Management and Prognosis of Chronic Pancreatitis in Chinese Population: A Retrospective Study显示文摘The purpose of this study was to investigate the etiology, pathological characteristics, management and prognosis of chronic pancreatitis in the Chinese population. The clinical data of 142 patients with chronic pancreatitis were retrospectively studied. All patients were of Chinese nationality and hospitalized from January 2008 to December 2011. Their ages ranged from 14 to 76 years, with a mean of 43 years. Of 142 patients, there were 72 cases of obstructive chronic pancreatitis(50.70%), 19 cases of alcoholic chronic pancreatitis(13.38%), 14 cases of autoimmune pancreatitis(9.86%) and 37 cases of undetermined etiology(26.06%). Pathologically, the average inflammatory mass diameter was 3.8±3.3 cm, biliary obstruction occurred in 36 cases, gall stones in 70 cases, calcification in 88 cases, ductal dilatation in 61 cases, side branch dilatation in 32 cases, ductal irregularity in 10 cases, lymphocytic inflammation in 23 cases, obliterative phlebitis in 14 cases, extra pancreatic lesion in 19 cases and fibrosis in 142 cases. Location of pancreatic lesion in the region of head(n=97), neck(n=16), body(n=12), tail(n=15) and whole pancreas(n=2) influenced the choice of surgical procedures. Ninety-four patients(66.20%) received surgical treatment and 33.80% received other treatments. After operation, 80.85% of 94 patients experienced decreased pain, and 8.51% of 94 showed recovery of endocrine function but with a complication rate of 12.77%. All the operations were performed successfully. According to the pain scale of European Organization for Research and Treatment of Cancer(QLQ-C30) a decrease from 76±22 to 14±18 was observed. Etiology, pathological characteristics, management and prognosis of chronic pancreatitis in the Chinese population vary from others. | Soriba Naby Camara Sonam Ramdany 赵刚 勾善淼 熊炯炘 杨智勇 殷涛 杨明 Oumar Taibata Balde Ahmed Boubacar Barry Seid.Adji 李想 金岩 吴河水 王春友 | 2015 | Journal of Huazhong University of Science and Technology(Medical Sciences)2015，35，3： | 2 |
| 18 | Design Optimization and Weight Reduction of 500 mL CSD PET Bottle through FEM Simulations显示文摘 | Carlos Alberto Silva De Miranda Jairo Jose Drummond Camara Olavo Pena Monken Claudio Gouvea Dos Santos | 2011 | 材料科学与工程(中英文B版)2011，1，7： | 2 |
| 19 | Mathematical Morphology Applied to Raster Generalization of Urban City Block Maps 显示文摘 | Manuel Antonio Urena Camara Francisco Javier Ariza Lopez | 2000 | Cartographica2000，37，1： | 1 |
| 20 | Using ontologies for integrated geographic information systems显示文摘 | Fonseca F Egenhofer M Agouris P Camara C | | 0，，03： | 1 |
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