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| 1 | Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas:10 year single-center experience and literature review显示文摘AIM:To report our experience with long-term outcomes after multimodal management therapy.METHODS:An observational retrospective study was performed containing seven patients with hepatoblastoma(Hbl)treated in our institution,a tertiary referral center,from 2003 to 2011.Demographic,preoperative,surgical,and outcome variables were collected.A survival analysis and a review of the current literature related to combination neoadjuvant chemotherapy and surgical resection on Hbl were performed.RESULTS:The median age at surgery was 14.4 mo,with a male to female ratio of 4:3.Pretext staging at diagnosis was as follows:stageⅠ,4 cases;stageⅡ,2 patients;and stageⅢ,1 case.Mean pretreatment tumor volume was 735 cm3.Five out of seven patients received neoadjuvant chemotherapy according to SIOPEL-3 or SIOPEL-6 protocols.Tumor volume and alphafetoprotein levels significantly dropped after neoadjuvant therapy.Surgical procedures performed included hemihepatectomies,segmentectomies and atypical resection.All patients received chemotherapy after surgery.Median postoperative hospital stay was 8 d.All patients were alive and disease-free after a median follow-up period of 23 mo.With regards to the literature review,seventeen articles were found that were related to our search.CONCLUSION:Our series shows how multimodal management of Hbl,exhaustive control and a meticulous surgical approach leads to almost 100%complete resection with optimal postoperative results. | Dolores Ayllon Teran Oscar Gómez Beltran Rubén Ciria Bru Elena Mateos González María José Pea Rosa Antonio Luque Molina Pedro López Cillero Javier Briceo Delgado | 2014 | World Journal of Gastroenterology2014，20，29： | 12 |
| 2 | Surgical resection of hepatocellular carcinoma in cirrhotic patients: Prognostic value of preoperative portal pressure显示文摘 | J Bruix A Castells J Bosch F Feu J Fuster JC Garcia-Pagan J Visa C Bru J Rodes | 1996 | Gastroenterology1996，，4： | 3 |
| 3 | Number and activation of circulating polymorphonuclear leukocytes and platelets are associated with neonatal respiratory distress syndrome severity显示文摘 | Brus F van Oeveren W Okken A | 1997 | Pediatrics1997，99，5： | 1 |
| 4 | Influence of alternating low frequency magnetic fields on reactivity of central dopamine receptors in neonatal 6-hydroxydopamine treated rats显示文摘 | Sieron A Brus R Szkilnik R Bioelectromagnetics | 2001 | Bioelectromagnetics2001，22，7： | 1 |
| 5 | Simple model for the ionization potential, electron affinity, and aqueous redox potential of small semiconductor crystallites 显示文摘 | BRUS L E A | 1983 | J Chem Phys1983，79，： | 1 |
| 6 | Uterine compression U-su- tures in primary postpartum hemorrhage after cesarean section: fertility preservation with a simple and effective technique显示文摘 | Haekethal A Bru~ D Oehmke F | 2008 | Hum Repred2008，23，1： | 1 |
| 7 | Number and activation of circulating polymorphonuclear leukocytes and platelets are associated with neonatal respiratory distress syndrome severity 显示文摘 | Brus F Van Oeveren W Okken A | 1997 | Pediatrics1997，99，5： | 1 |
| 8 | Nanoscale Atoms in Solid- State Chemistry 显示文摘 | Roy X Lee C H Crowther A C Schenck C L Besara T Lalancette R A Siegrist T Stephens P W Brus L E Kim P Steigerwald M L Nuckolls C | 2013 | Science2013，，341： | 1 |
| 9 | Wedged hepatic venous pressure adequately reflects portal pressure in hepatitis C vires-related cirrhosis显示文摘 | PERELLO A ESCORSELL A BRU C | 1999 | Hepatology1999，30，： | 1 |
| 10 | Novel procedure for extraction of a latent grape polyphenoloxidase using temperature-induced phase separation in triton x-114显示文摘 | FERRET A S BRU R CARMONA F G | 1989 | Plant Physiol1989，91，： | 1 |
| 11 | Is microbubble-enhanced ultrasonography sufficient for assessment of response to percutaneous treatment in patients with early hepatocellular carcinoma?显示文摘 | R. Vilana L. Bianchi M. Varela C. Nicolau M. Sánchez C. Ayuso M. García M. Sala J. M. Llovet J. Bruix C. Bru | 2006 | European Radiology2006，，11： | 1 |
| 12 | Treatment of small hepatocellar cm'cinonm in cirrhotic patients: a cohort study comparing surgical resection and pereutaneous ethanol injection显示文摘 | Castells A Bruix J Bru C | 1993 | Hepatology1993，18，： | 1 |
| 13 | Ag nanocrystal junctions as the site for surface-enhanced Raman scattering of single rhodamine 6G molecules 显示文摘 | Michaels A M Jiang J Brus L | 2000 | j Phys Chem B2000，104，50： | 1 |
| 14 | Mapping groundwater dynamics using multiple sources of exhaustive high resolution data显示文摘 | Finke P A Brus D J Bierkens M F P | 2004 | Geoderma2004，，123： | 1 |
| 15 | Human mesenchymalstem cells reprogram adult cardiomyocytes toward a progenitor -like state through partial cell fusion and mitochondria transfer显示文摘 | Acquistapace A Bru T Lesault PF | 2011 | Stem Cells2011，29，5： | 1 |
| 16 | Surface enhanced Raman spectroscopy of individual rhodamine 6G molecules on large Ag nanocrystals显示文摘 | MICHAELS A M NIRMAL M BRUS L E | 1999 | J Am Chem Soc1999，121，： | 1 |
| 17 | Surgical resection of hepatocellular carcinoma in cirrhotic patients: Prognostic value of preoperative portal pressure显示文摘 | J Bruix A Castells J Bosch F Feu J Fuster JC Garcia-Pagan J Visa C Bru J Rodes | 1996 | Gastroenterology1996，，4： | 1 |
| 18 | The use of elec-tromagnetic measurements of apparent soil electrical conductivity to pre-dict the boulder clay depth显示文摘 | BRUS D J KNOTTERS M DOOREMOLEN W A | 1992 | Geoderma1992，55，1： | 1 |
| 19 | Modifying the cellular transport of DNA-based vaccines alters the immune response to hantavirus nucleocapsid protein显示文摘 | Go¨ran Bucht a * Katarina Brus Sjo¨lander | 2001 | Vaccine2001，19，： | 1 |
| 20 | Fluctuations and local symmetry in single-molecule rhodamine 6G Raman scat- tering on silver nanocrystal aggregates 显示文摘 | Bosnick K A Jiang J Brus L E | 2002 | The Journal of Physical Chemistry B2002，106，33： | 1 |
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