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| 1 | Treatment of hepatocellular carcinoma in patients with portal vein tumor thrombosis: Beyond the known frontiers显示文摘Hepatocellular carcinoma is one of the most frequent malignant tumors worldwide:Portal vein tumor thrombosis(PVTT)occurs in about 35%-50%of patients and represents a strong negative prognostic factor,due to the increased risk of tumor spread into the bloodstream,leading to a high recurrence risk.For this reason,it is a contraindication to liver transplantation and in several prognostic scores sorafenib represents its standard of care,due to its antiangiogenetic action,although it can grant only a poor prolongation of life expectancy.Recent scientific evidences lead to consider PVTT as a complex anatomical and clinical condition,including a wide range of patients with different prognosis and new treatment possibilities according to the degree of portal system involvement,tumor biological aggressiveness,complications caused by portal hypertension,patient’s clinical features and tolerance to antineoplastic treatments.The median survival has been reported to range between 2.7 and 4 mo in absence of therapy,but it can vary from 5 mo to 5 years,thus depicting an extremely variable scenario.For this reason,it is extremely important to focus on the most adequate strategy to be applied to each group of PVTT patients. | Lucia Cerrito Brigida Eleonora Annicchiarico Roberto Iezzi Antonio Gasbarrini Maurizio Pompili Francesca Romana Ponziani | 2019 | World Journal of Gastroenterology2019，25，31： | 21 |
| 2 | Microscopic colitis显示文摘Microscopic colitis may be defined as a clinical syndrome, of unknown etiology, consisting of chronic watery diarrhea, with no alterations in the large bowel at the endoscopic and radiologic evaluation. Therefore, a definitive diagnosis is only possible by histological analysis. The epidemiological impact of this disease has become increasingly clear in the last years, with most data coming from Western countries. Microscopic colitis includes two histological subtypes [collagenous colitis (CC) and lymphocytic colitis (LC)] with no differences in clinical presentation and management. Collagenous colitis is characterized by a thickening of the subepithelial collagen layer that is absent in LC. The main feature of LC is an increase of the density of intra-epithelial lymphocytes in the surface epithelium. A number of pathogenetic theories have been proposed over the years, involving the role of luminal agents, autoimmunity, eosinophils, genetics (human leukocyte antigen), biliary acids, infections, alterations of pericryptal fibroblasts, and drug intake; drugs like ticlopidine, carbamazepine or ranitidine are especially associated with the development of LC, while CC is more frequently linked to cimetidine, non-steroidal antiinflammatory drugs and lansoprazole. Microscopic colitis typically presents as chronic or intermittent watery diarrhea, that may be accompanied by symptoms such as abdominal pain, weight loss and incontinence. Recent evidence has added new pharmacological options for the treatment of microscopic colitis:the role of steroidal therapy, especially oral budesonide, has gained relevance, as well as immunosuppressive agents such as azathioprine and 6-mercaptopurine. The use of anti-tumor necrosis factoragents, infliximab and adalimumab, constitutes a new, interesting tool for the treatment of microscopic colitis, but larger, adequately designed studies are needed to confirm existing data. | Gianluca Ianiro Giovanni Cammarota Luca Valerio Brigida Eleonora Annicchiarico Alessandro Milani Massimo Siciliano Antonio Gasbarrini | 2012 | World Journal of Gastroenterology2012，18，43： | 4 |
| 3 | Experimental and Theoretical Analysis of an Optical Current Sensor for High Power Systems显示文摘一个磁电机光的传感器,用双照测定偏振的处理计划,在高电压线为当前的 metering 和保护应用被评估。传感器刻度和分辨率在 1550-nm 乐队用照明处于不同运作的条件被获得。获得的结果显示了经由连接在标准高力量格子安装了的光地面电线(OPGW ) 讯问如此的传感器的可行性。测定偏振的体积光当前的传感器理论上也被学习,并且就实际推广而言的错误的不同来源的效果被评估。特别地,从在一个树阶段系统的外部磁场的干扰被分析。 | A. C. S. BRIGIDA I. M. NASCIMENTO S. MENDONCA J. C. W. A. COSTA M. A. G. MARTINEZ, J. M. BAPTISTA,P. A. S. JORGE J. C. W. A. COSTA, M. A. G. MARTINEZ, J. M. BAPTISTA J. M. BAPTISTA P.A.S. JORGE | 2013 | Photonic Sensors2013，3，1： | 2 |
| 4 | 显示文摘 | Brigida Allieri A Laura E Depero Marino A | 2000 | Materials Chemistry and Physics2000，66，： | 1 |
| 5 | Potential allelopathic effects of stilbenoids and flavonoids from leaves of Carex distachya Desf 显示文摘 | Antonio F Brigida D Severina P | 2008 | Biochem Syst Ecol2008，36，9： | 1 |
| 6 | ‘ Limoncella' apple, an Italian apple cultivar: Phenolic and flavonoid con- tents and antioxidant activity显示文摘 | D' Abrosca Brigida Pacifico Severina Cefarelli Giuseppe | 2007 | Food Chemistry2007，104，4： | 1 |
| 7 | Gut microbiota and metabolic syndrome显示文摘 | Francesca D’Aversa Annalisa Tortora Gianluca Ianiro Francesca Romana Ponziani Brigida Eleonora Annicchiarico Antonio Gasbarrini | 2013 | Internal and Emergency Medicine2013，，1： | 1 |
| 8 | Early prediction of response to Sorafenib in patients with advanced hepatocellular carcinoma: the role of dynamic contrast enhanced ultrasound显示文摘 | Zocco Maria Assunta Garcovich Matteo Lupascu Andrea Di Stasio Enrico Roccarina Davide Annicchiarico Brigida Elenora Riccardi Laura Ainora Maria Elena Ponziani Francesca Caracciolo Gianluigi Rapaccini Gian Lodovico Landolfi Raffaele Siciliano Massimo Pompi | 2013 | Journal of Hepatology2013，，： | 1 |
| 9 | Second generation ultrasonographic contrast agents in the diagnosis of neoplastic thyroid nodules显示文摘 | APPETECCHIA M BACARO D BRIGIDA R | 2006 | J Exp Clin Cancer Res2006，25，11： | 1 |
| 10 | Second generation ultrasonographic contrast agents in the diagnosis of neoplastic thyroid nodules 显示文摘 | APPETECCHIA M BACARO D BRIGIDA R | 2006 | J Exp Ciin Caneer Res2006，25，3： | 1 |
| 11 | Lignans and neolignans from Brassica fruticulosa:effects on seed germination and plant growth显示文摘 | Francesca C Brigida D Marina D | | 0，，： | 1 |
| 12 | Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: A controlled study显示文摘 | Angelo Iacobellis Massimo Siciliano Francesco Perri Brigida E. Annicchiarico Gioacchino Leandro Nazario Caruso Laura Accadia Giuseppe Bombardieri Angelo Andriulli | 2006 | Journal of Hepatology2006，，2： | 1 |
| 13 | Second generation ultrasonographic contrast agents in the diagnosis of neoplastic thyroidnodules显示文摘 | Appetecchia M Bacro D Brigida R | | 0，，03： | 1 |
| 14 | Second generation ultrasonographic contrast agents in the diagnosis of neoplastic thyroid nodules显示文摘 | Appetecchia M Bacaro D Brigida R | 2006 | J Exp Clin Cancer Res2006，25，3： | 1 |
| 15 | Second generation ul- trasonographic contrast agents in the diagnosis of neoplastic thy- roid nodules显示文摘 | Appetecchia M Bacaro D Brigida R | 2006 | J Exp Clin Cancer Res2006，25，3： | 1 |
| 16 | Importance of phenolic compounds for the characterization of fruit juices 显示文摘 | Brigida Femendez de Simon | 1992 | J Agric Food Chem1992，40，： | 1 |
| 17 | Second generation ultrasonographic contrast agents in the diagnosis of neoplastic thyroid nodules显示文摘 | Appetecchia M Bacro D Brigida R | 2006 | J Exp Clin Cancer Res2006，25，3： | 1 |
| 18 | Second generation ultra- sonographic contrast agents in the dignosis of neoplastic thyroid nodules 显示文摘 | Appeteeehia M BacaroD Brigida R | 2006 | Exp Clin Canc er Res2006，25，3： | 1 |
| 19 | Characterization of volatile constituents in commercial oak wood chips显示文摘 | BRIGIDA F D S IRIA M ESTRELLA C | 2010 | Journal of Agricultural and Food Chemistry2010，58，17： | 1 |
| 20 | Second generation ultrasonographic contrast agents in the diagnosis of neoplastic thyroid nodules显示文摘 | Appetecchia M Bacaro D Brigida R | 2006 | J Exp Clin Cancer Res2006，25，3： | 1 |
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