|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment显示文摘 | Ajit K. Sarmah Michael T. Meyer Alistair B.A. Boxall | 2006 | Chemosphere2006，，5： | 10 |
| 2 | Prevalence of anal fistula in the United Kingdom显示文摘BACKGROUND Anal fistula is a pathological connection between the anal canal and perianal skin, which most commonly develops from an infected anal crypt. While the majority of anal fistulas are idiopathic, they are also associated with Crohn’s disease (CD) and other inflammatory conditions. The prevalence of anal fistula is estimated to be 1-2 per 10000 patients, but population-based studies on anal fistula epidemiology are limited and outdated. AIM To assess the prevalence of anal fistula and relevant comorbidities, with and without CD in the United Kingdom and Europe. METHODS A retrospective population-representative observational cohort study was performed in The Health Improvement Network (THIN), a United Kingdom primary care database. Mid-year point prevalence of anal fistula was calculated on the first of July for each year between 2014 and 2017. Estimates were calculated for anal fistula overall and by CD status and standardized to the United Kingdom and European population. Prevalence of relevant comorbidities including lymphogranuloma venereum, hidradenitis suppurativa, anal presentation of sexually transmitted diseases, diabetes mellitus, and radiation in the pelvic area was reported. RESULTS The United Kingdom-standardized overall point prevalence of anal fistula was 1.80 (95%CI: 1.65-1.94) per 10000 patients in 2017, while the Europe standardized estimate was 1.83 (95%CI: 1.68-1.98) per 10000 patients. Both these standardized point prevalence estimates ranged from 1.89 to 2.36 between 2014-2016. The United Kingdom-standardized point prevalence of anal fistula without CD was 1.35 (95%CI: 1.23-1.48) per 10000 patients, while the Europe-standardized estimate was 1.39 (95%CI: 1.26-1.52) per 10000 patients. In contrast, the standardized point prevalence estimate of anal fistula with CD was lower for both United Kingdom and Europe (0.44;95%CI United Kingdom: 0.37-0.52, 95%CI Europe: 0.37-0.51) per 10000 patients in 2017. In 2017, 19% of anal fistula patients without CD and 13% of anal fistula patients with CD had at least one relevant comorbidity. These results show that anal fistulas are infrequent in the general population. 24.5% of prevalent anal fistulas are associated with CD, but other potentially etiological comorbidities are rare. CONCLUSION This real-world evidence study estimated the United Kingdom-standardized prevalence of anal fistula was 1.80 per 10000 patients in 2017. Approximately 25% of cases may be associated with CD, while other comorbidities are rare. | Suvi RK Hokkanen Naomi Boxall Javaria Mona Khalid Dimitri Bennett Haridarshan Patel | 2019 | World Journal of Clinical Cases2019，7，14： | 7 |
| 3 | Application of nanoparticle tracking analysis for characterising the fate of engineered nanoparticles in sediment-water systems显示文摘Novel applications of nanotechnology may lead to the release of engineered nanoparticles(ENPs), which result in concerns over their potential environmental hazardous impact. It is essential for the research workers to be able to quantitatively characterise ENPs in the environment and subsequently to assist the risk assessment of the ENPs. This study hence explored the application of nanoparticle tracking system(NTA) to quantitatively describe the behaviour of the ENPs in natural sediment-water systems. The NTA allows the measurement of both particle number concentration(PNC) and particle size distribution(PSD) of the ENPs. The developed NTA method was applied to a range of gold and magnetite ENPs with a selection of surface properties. The results showed that the positively-charged ENPs interacted more strongly with the sediment than neutral and negatively-charged ENPs. It was also found that the citrate coated Au ENPs had a higher distribution percentage(53%) than 11-mercaptoundecanoic acid coated Au ENPs(20%) and citrate coated magnetite ENPs(21%). The principles of the electrostatic interactions between hard(and soft) acids and bases(HSAB) are used to explain such behaviours; the hard base coating(i.e. citrate ions) will interact more strongly with hard acid(i.e. magnetite) than soft acid(i.e. gold).The results indicate that NTA is a complementary method to existing approaches to characterise the fate and behaviour of ENPs in natural sediment. | Ping Luo Alejandro Roca Karen Tiede Katie Privett Jiachao Jiang John Pinkstone Guibin Ma Jonathan Veinot Alisatair Boxall | 2018 | Journal of Environmental Sciences2018，30，2： | 6 |
| 4 | Achieving Competitive Advantage through Human Resource Strategy: Towards a Theory of Industry Dynamics显示文摘 | Boxall P | 1998 | Human Resource Management Review1998，，： | 2 |
| 5 | A global per-spective on the use,sales,exposure pathways,occurrence,fate and effects of veterinary antibiotics(VAs)in the environ-ment显示文摘 | SARMAH A K MEYER M T BOXALL A | 2006 | Chemosphere2006，65，5： | 1 |
| 6 | A global perspective on the use,sales,exposure pathways,occurrence,fate and effects of veterinary antibiotics (Vas) in the environment显示文摘 | Sarmah A K Meyer M T Boxall A B A | 2006 | Chemosphere2006，，65： | 1 |
| 7 | Bcl-2 family protein expression and platinum drug resistance in ovarian carinoma显示文摘 | Beale PJ Rogers P Boxall F | | 0，，02： | 1 |
| 8 | Modeling combined effects of pulsed exposure to carbaryl and chlorpyrifos on gammaruspulex 显示文摘 | Ashauer R Boxall A B A Brow C D | 2007 | Environmental Science and Technology2007，41，： | 1 |
| 9 | A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment显示文摘 | Sarmah A K Meyer M T Boxall A | 2006 | Chemosphere2006，65，5： | 1 |
| 10 | Achieving Competitive Advantage Through Human Resource Strategy: Towards a Theory of Industry Dynamics 显示文摘 | Peter Boxall | 1996 | Human Resource Management Review1996，8，3： | 1 |
| 11 | Room temperature ionic liquids and their mixtures-a review显示文摘 | Marsh K N Boxall J A Lichtenthaler R | 2004 | Fluid Phase Equilibria2004，219，： | 1 |
| 12 | Predicting effects on aquatic organisms from fluctuating or pulsed exposure to pesticides 显示文摘 | Ashauer R Boxall A Brown C | 2006 | Environmental Toxicology and Chem- istry2006，25，7： | 1 |
| 13 | Validation of a Three-Dimensional Numerical Code in the Simulation of Pseudo-Natural Meandering Flows显示文摘 | WILSON C A M E BOXALL J B GUYMER I | 2003 | Journal of Hydraulic Engineering2003，129，10： | 1 |
| 14 | Room temperature ionic liquids and their mixtures--a review显示文摘 | MARSH K N BOXALL J A LICHTENTHALER R | 2004 | Fluid Phase Equilibria2004，219，： | 1 |
| 15 | Column Studies to Investigate the Fate of Veterinary Antibiotics in Clay Soils following Slurry Application to Agricultural Land显示文摘 | KAY P BLACKWELL P A BOXALL A B A | 2005 | Chemosphere2005，60，4： | 1 |
| 16 | Management of severe spondylolisthesis in children and adolescents 显示文摘 | Boxall D Bradford DS Winter RB | 1979 | Bone Joint surg Am1979，61，： | 1 |
| 17 | Simulating toxicity of carbaryl to gammarus pulex after sequential pulsed exposure 显示文摘 | Ashauer R Boxall A B A Brown C D | 2007 | Environmental Science and Technology2007，41，： | 1 |
| 18 | The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria显示文摘 | Elizabeth MH Wellington Alistair BA Boxall Paul Cross Edward J Feil William H Gaze Peter M Hawkey Ashley S Johnson-Rollings Davey L Jones Nicholas M Lee Wilfred Otten Christopher M Thomas A Prysor Williams | 2013 | The Lancet Infectious Diseases2013，，2： | 1 |
| 19 | Fate of veterinary antibiotics in a macroporous tile drained clay soil显示文摘 | Kay P Blaekwell P A Boxall A B A | 2004 | Environmental Toxicology and Chemistry2004，23，5： | 1 |
| 20 | Veterinary medicines in the environment显示文摘 | Boxall A B A Fogg L A Kay P Blackwell P A Pemberton E J Croxford A | 2004 | Reviews in Environmental Contamination and Toxicology2004，180，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员