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| 1 | White light endoscopy,narrow band imaging and chromoendoscopy with magnification in diagnosing colorectal neoplasia显示文摘AIM:To evaluate the sensitivity(Sn),specificity(Sp),positive predictive value(PPV) and negative predictive value(NPV) of 3 different techniques:high resolution white light endoscopy(WLE),Narrow Band Imaging(NBI) and Chromoendoscopy(CHR),all with magnification in differentiating adenocarcinomas,adenomatous and hyperplastic colorectal polyps.METHODS:Each polyp was sequentially assessed first by WLE,followed by NBI and finally by CHR.Digital images of each polyp with each modality were taken and stored.Biopsies or polypectomies were then performed followed by blinded histopathological analysis.Each image was blindly graded based on the Kudo's pit pattern(KPP).In the assessment with NBI,the mesh brown capillary network pattern(MBCN) of each polyp was also described.The Sn,Sp,PPV and NPV of differentiating hyperplastic(Type Ⅰ & Ⅱ-KPP,Type Ⅰ-MBCN) adenomatous(Types Ⅲ,Ⅳ-KPP,Type Ⅱ-MBCN) and carcinomatous polyps(Type Ⅴ-KPP,Type Ⅲ-MCBN) was then compared with reference to the final histopathological diagnosis.RESULTS:A total of 50 colorectal polyps(5 adenocarcinomas,38 adenomas,7 hyperplastic) were assessed.CHR and NBI [KPP,MBCN or the combined classification(KPP & MBCN)] were superior to WLE in the prediction of polyp histology(P < 0.001,P=0.002,P=0.001 and P < 0.001,respectively).NBI,using the MBCN pattern or the combined classification showed higher numerical accuracies compared to CHR,but this was not statistically significant(P=0.625,0.250).CONCLUSION:This feasibility study demonstrated that this combined classification with NBI could potentially be useful in routine clinical practice,allowing the endoscopist to predict histology with higher accuracies using a less cumbersome and technically less challenging method. | Rajvinder Singh Victoria Owen Anthony Shonde Philip Kaye Christopher Hawkey Krish Ragunath | 2009 | World Journal of Gastrointestinal Endoscopy2009，1，1： | 3 |
| 2 | Diagnosis of autoimmune gastritis by high resolution magnification endoscopy显示文摘胃的萎缩的内视镜的可视化通常不与常规内视镜检查法是可行的。放大内视镜检查法是有用的分析潜水艇没有织物的上皮的微脉管的建筑学以及粘膜表面微观结构活体检视。用这种技术,我们能描述正常胃的微脉管系统模式,我们也在自体免疫的萎缩性胃炎的二种情况中识别了典型模式。 | George K Anagnostopoulos Krish Ragunath Anthony Shonde Christopher J Hawkey | 2006 | World Journal of Gastroenterology2006，12，28： | 3 |
| 3 | Narrow band imaging for characterization of high grade dysplasia and specialized intestinal metaplasia in Barrett’s esophagus: a meta-analysis显示文摘 | J. Mannath V. Subramanian C. Hawkey K. Ragunath | 2010 | Endoscopy2010，，05： | 2 |
| 4 | Consensus statement on antimicrobial therapy of intra-abdominal infections in Asia 显示文摘 | Hsueh PR Hawkey PM | 2007 | Int J Antimicrob Agents2007，30，： | 1 |
| 5 | COX-2 inhibitors 显示文摘 | Hawkey CJ | 1999 | Lancet1999，353，： | 1 |
| 6 | Radomised controlled trial of HP eradication in patients on non-steroidal anti-inflammatory drugs显示文摘 | Hawkey CJ Tulassay Z Szczepanski L | 1998 | Lancet1998，352，9： | 1 |
| 7 | Incidence of Class 1 integrons in a quaternary ammonium compound- polluted Environment显示文摘 | Gaze WH Abdouslam N Hawkey PM | 2005 | Antimicrob Agents Chemother2005，49，5： | 1 |
| 8 | Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou,PR China 显示文摘 | Zhao Z Zhang F Xu M Huang K Zhong W Cai W Yin Z Huang S Deng Z Wei M Xiong J Hawkey PM | 2003 | J Med Microbiol2003，52，8： | 1 |
| 9 | Proton pump inhibitors: pharmacology and rationale for use in gastrointestinal disorders 显示文摘 | Richardson P Hawkey C J Stack WA | 1998 | Drugs1998，56，3： | 1 |
| 10 | Prevalence and clonality of extended-spectrumβ-lactamases in Asia显示文摘 | Hawkey PM | 2008 | Clin Microbiol Infect2008，141，： | 1 |
| 11 | The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria显示文摘 | Elizabeth MH Wellington Alistair BA Boxall Paul Cross Edward J Feil William H Gaze Peter M Hawkey Ashley S Johnson-Rollings Davey L Jones Nicholas M Lee Wilfred Otten Christopher M Thomas A Prysor Williams | 2013 | The Lancet Infectious Diseases2013，，2： | 1 |
| 12 | 显示文摘 | Hawkey C J Langman MJS | 2003 | Gut2003，52，4： | 1 |
| 13 | Validation of use of whole-cell repetitive extragenic palindromic sequence-based PCR (REP-PCR) for typing strains belonging to the Acinetobacter cal- coaeeticus-Acinetobaeter baumannii complex and application of the method to the investigation of a hospital outbreak显示文摘 | Snelling AM Gerner-Smidt P Hawkey PM | 1996 | J Clin Microbi- ol1996，34，5： | 1 |
| 14 | Incidence of class 1 integrons in a quaternary ammonium compound-polluted environment显示文摘 | Gaze WH Abdouslam N Hawkey PM | 2005 | Antimierob Agents Chemother2005，49，5： | 1 |
| 15 | Social construcfivism and asynchronous text-based discussion: a case study with trainee teachers 显示文摘 | Hawkey K | 2003 | Education and Information Technologies2003，8，2： | 1 |
| 16 | Nonsteroidal antiinflammatory drugs and the small intestine 显示文摘 | Fortun P J Hawkey C J | 2007 | Curr Opin Gastroenterol2007，23，2： | 1 |
| 17 | Expression ofin-terleukin 1 beta and interleukin 1 beta converting en- zymeby intestinal macrophages in health and inflammatory bowel disease显示文摘 | McAlindon ME Hawkey CJ Mahida YR | 1998 | Gut1998，42，： | 1 |
| 18 | Prevalence and clonality of extended spectrum beta lac- tamasesin Asia 显示文摘 | Hawkey PM | 2008 | Clin Microbiol Infect2008，14，： | 1 |
| 19 | Prevalence and clonality of extended-spectrum -lacta- mases in Asia显示文摘 | Hawkey PM | 2008 | Clin Micrebiol Infect2008，14，1： | 1 |
| 20 | Nonsteroidal anti-inflammatory drug gastropathy显示文摘 | hawkey CJ | | 0，，： | 1 |
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