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| 1 | The multiple-kinase inhibitor lenvatinib inhibits the proliferation of acute myeloid leukemia cells显示文摘Background:Current chemotherapy for acute myeloid leukemia(AML)mainly involves cytotoxic agents such as doxorubicin(DNR),mitoxantrone(Mito)or 2‐aminopurine‐6‐thiol(6‐TG).However,because these agents are relatively ineffective,discovering other more effective drugs for AML treatment would be valuable.Methods:The in vitro antitumor effect of lenvatinib on AML cells was examined using the colorimetric MTT assay for assessing cell metabolic activity.AML cells mixed with Poloxamer 407 were injected into nude mice to form subcutaneous tumors.Tumorbearing mice received lenvatinib by oral administration.The antitumor effect of lenvatinib was established by measuring tumor volumes and weights.Results:Lenvatinib inhibited the growth of AML cells in a dose‐dependent manner.We used AML cells to establish subcutaneous tumor tissues by mixing the cell suspension with Poloxamer 407.Poloxamer 407 alone did not influence the subcutaneous growth of AML cells.Treatment of lenvatinib inhibited in vivo tumor growth of AML cells.Conclusion:The multiple‐kinase inhibitor lenvatinib inhibits the in vitro proliferation of AML cells,and restricts the in vivo growth of AML tumors. | Fan Feng Xiaojuan Li Ruisheng Li Boan Li | 2019 | Animal Models and Experimental Medicine2019，2，3： | 2 |
| 2 | Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients显示文摘 | Penuelas I Mazzolini G Boan JF | 2005 | Gastroenterology2005，128，7： | 1 |
| 3 | Salivary enzyme polymorphisms(Set,Sgd and AMY1) in the Galician population显示文摘 | Caeiro JLB | 1988 | Hum Hered1988，38，： | 1 |
| 4 | Analysis of molding process parameters of bra cup显示文摘 | WU Hanyan ZHANG Xin YING Boan | 2009 | Textile Bioengineering and Informatics Symposium Proceedings2009，5，6： | 1 |
| 5 | The structure of Beauvericin, A new depsipepdicle antibiotic toxic to artemia salina显示文摘 | HAMILL P L HIGGEUS C E BOAN H E | 1969 | Tetrahedron Letters1969，，49： | 1 |
| 6 | Lonaterm weight loss maintenance in the United States显示文摘 | Kraschnewski JL Boan J Esposito J | 2010 | Int J Obes2010，34，： | 1 |
| 7 | Cognitive - Behavior Modification and Organizatiional Culture 显示文摘 | Boan D M | 2006 | Consulting Psychology Journal: Practice and Research2006，58，1： | 1 |
| 8 | The Impact of Cultural Value Diversity on Muhicultural Team Performance显示文摘 | David M Boan | 2005 | Advances in International Management2005，18，： | 1 |
| 9 | Radioembolization using 90Y-resin microspheres for patients with advanced hepatocellular carcinoma显示文摘 | Sangro B Bibao JI Boan J | 2006 | Int J Radiat Oncol Biol Phys2006，66，3： | 1 |
| 10 | Salivary enzyme polymorphisms(Set, Sgd and AMY1) in the Galician population显示文摘 | Caeiro JLB | 1988 | Hum Hered1988，38，： | 1 |
| 11 | Anal- ysis of molding process parameters of bra cup 显示文摘 | WU Hanyan ZHANG Xin YING Boan | 2009 | Textile Bioengineering and Informatics Symposium Proceedings2009，5，6： | 1 |
| 12 | Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients 显示文摘 | Penuelas I Mazzolini G Boan JF | 2005 | Gastroenterology2005，128，7： | 1 |
| 13 | The structure of Beauvericin, a new depsipepdicle antibiotic toxic to Artemia salina显示文摘 | HAMIL P L HIGGEUS C E BOAN H E | 1969 | Tet Lett1969，，49： | 1 |
| 14 | Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients显示文摘 | Penuelas I Mazzolini G Boan JF | | 0，，07： | 1 |
| 15 | Radioembolization using 90Y - resin microspheres for patients with advanced hepatocellular carcinoma显示文摘 | Sangro B Bilbao JI Boan J | 2006 | Int J Radiat Oncol Biol Phys2006，66，3： | 1 |
| 16 | A new way to prepare SiO2 nanowire 显示文摘 | Hu Weibing Shi Boan Dan Youmeng | 2002 | Science in China ( Series B )2002，32，2： | 1 |
| 17 | Epidemiological analysis of group A streptococci recovered from patients in China显示文摘 | Jing Hongbo Ning Boan Hao Huangjie | 2006 | J Med Microbiol2006，55，8： | 1 |
| 18 | Persistent racial disparity in stroke hos- pitalization and economic impact in young adults in the buckle of stroke belt 显示文摘 | Boan AD Feng WW Ovbiagele B | 2014 | Stroke2014，45，： | 1 |
| 19 | Radioembolization using 90Y-resin microspheres for patients with advanced hepatocellular carcinoma显示文摘 | Bruno Sangro Jose I. Bilbao Jose Boan Antonio Martinez-Cuesta Alberto Benito Javier Rodriguez Angel Panizo Belen Gil Mercedes Inarrairaegui Ignacio Herrero Jorge Quiroga Jesus Prieto | 2006 | International Journal of Radiation Oncology, Biology, Physics2006，，3： | 1 |
| 20 | Sol-gel derived hydroxyapatite films on alumina substrates显示文摘 | Hwang Kyuseog Song Jongeun Kang Boan | 2000 | Surface and Coatings Technology2000，123，23： | 1 |
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