维普中文期刊产品整合服务
64篇 您的检索式:作者名="Blessinger"
    题名 作者 年代 出处 被引量
1Therapeutic regulation of autophagy in hepatic metabolism显示文摘Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especially relevant in the liver, a key metabolic organ thatgoverns body energy metabolism. Autophagy’s role in hepatic energy regulation has just begun to emerge and autophagy seems to have a much broader impact than what has been appreciated in the field. Though classically known for selective or bulk degradation of cellular components or energy-dense macromolecules, emerging evidence indicates autophagy selectively regulates various signaling proteins to directly impact the expression levels of metabolic enzymes or their upstream regulators. Hence, we review three specific mechanisms by which autophagy can regulate metabolism: A) nutrient regeneration, B) quality control of organelles, and C) signaling protein regulation. The plasticity of the autophagic function is unraveling a new therapeutic approach. Thus, we will also discuss the potential translation of promising preclinical data on autophagy modulation into therapeutic strategies that can be used in the clinic to treat common metabolic disorders.Katherine Byrnes Sophia Blessinger Niani Tiaye Bailey Russell Scaife Gang Liu Bilon Khambu 2022Acta Pharmaceutica Sinica B2022,12,1:11
2Computed tomography of normal distal tibioibular syndesmosis显示文摘Elgafy H Semaan HB Blessinger B 2010Skeletal Radiol2010,39,6:1
3Brown adipose tissue thermogenesis heats brain and body as part of the brain-coordinated ultradian basic rest-activity cycle显示文摘Y. Ootsuka R.C. de Menezes D.V. Zaretsky A. Alimoradian J. Hunt A. Stefanidis B.J. Oldfield W.W. Blessing 2009Neuroscience2009,,2:1
4Computed to- mography of normal distal tibiofibular syndesmosis 显示文摘Elgafy H Semaan HB Blessinger B 2010Skeletal Radiol2010,39,6:1
5High-resolution CCD camera for industrial imaging显示文摘MARTIN G J BLESSINGER K V VEITS C 1901SPIE1901,,:1
6Highly Cited Articles in Library and In- formation Science: An Analysis of Content and Authorship Trends显示文摘Blessinger K Hrycaj P 2010Library & Information Science Research2010,322,:1
7High-resolution CCD camera for industrial imaging显示文摘MARTIN G J BLESSINGER KV VEITS C 1901SPIE1901,,:1
8Walking and running economy:inverse association with peak oxygen uptake显示文摘Sawyer B Blessinger J Irving B 0,,11:1
9Passive autofocus for digital endoscopic imaging systems显示文摘BLESSING P ORELLI A V NIEDERER P 0,,:1
10Acoustic emission monitoring of high speed grinding of silicon nitride显示文摘T.W. Hwang E.P. Whitenton N.N. Hsu G.V. Blessing C.J. Evans 2000Ultrasonics2000,,1:1
11Results of the phase III,placebo-controlled trial(SUCCEED)evaluating the mTOR inhibitor ridaforolimus(R)as maintenance therapy in advanced sarcoma patients(pts)fol owing clinical benefit from prior standard cytotoxic chemotherapy(CT)显示文摘Chawla SP Blessing J Ray-Coquard I 0,,:1
12Correlation of serum brain natriuretic peptide with hyponatremia and delayed ischemic neurologicrl deficits after subarachnoid hemorrhage显示文摘McGirt MJ Blessing R Nimjee S M 0,,06:1
13Carcinosarcoma (malignant mixed mesodermal tumor) of the uerus A gynecologic oncology group pathologic study of 203 cases显示文摘Silverberg SG Major FJ Blessing JA 0,,:1
14Fixed-dose rate gemcitabine plus docetaxel as first-line therapy for metastatic uterine leiomyosarcoma:a Gynecologic Oncology Group phase II trial显示文摘Hensley ML Blessing JA Mannel R 0,,:1
15Challenges of spine surgery in obese patients显示文摘Elafy H O' Brien P Blessinger B 2012Am J Orthop2012,41,:1
16Cisplatin and irinotecan in squamous cell carcinoma of the cervix:a phase Ⅱ study of the gynecologic oncology group显示文摘Muggia FM Blessing JA McGehee R 0,,:1
17Computed tomography of normal distal tibiofibular syndesmosis显示文摘Elgafy H Semaan HB Blessinger B 2010Skeletal Radiol2010,39,6:1
18Risk factors and recurrent patterns in stage Ⅰ endometrial carcinoma显示文摘DiSaia PJ Creasman WT Boronow RC Blessing JA 0,,:1
19Highly cited articles in library and information science: An analysis of content and authorship trends显示文摘Blessinger K Hrycaj P 2010Library & Information Science Research2010,32,2:1
20Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes显示文摘Manfred Ogris Greg Walker Thomas Blessing Ralf Kircheis Markus Wolschek Ernst Wagner 2003Journal of Controlled Release2003,,1:1
返回顶部 每页显示:
共4页 首页 上一页 第1页 下一页 末页 /4 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费