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425篇 您的检索式:作者名="Bitzer"
    题名 作者 年代 出处 被引量
1Does foreign direct investment transfer technology across borders? New evidence显示文摘Jürgen Bitzer Monika Kerekes 2008Economics Letters2008,,3:4
2用于大车的电液助力转向系统:EPHS-Gen C显示文摘厂商们正在争相提高各类大型车辆的燃油经济性,这包括D级、E级乘用车以及轻型商用车。电液助力转向(EPHS)的最新一代产品Gen C,以成熟的技术为基础,有助于降低能耗,节约近3.0~3.5%。Gen C能够满足大型车辆对于较高齿条负载和高频率按需辅助的需求。Thilo Bitzer 2011汽车与配件2011,,36:3
3Bifunctional chimeric SuperCD suicide gene -YCD: YUPRT fusion is highly effective in a rat hepatoma model显示文摘AIM: To investigate the effects of catalytically superior gene-directed enzyme prodrug therapy systems on a rat hepatoma model.METHODS: To increase hepatoma cell chemosensitivity for the prodrug 5-fluorocytosine (5-FC), we generated a chimeric bifunctional SuperCD suicide gene, a fusion of the yeast cytosine deaminase (YCD) and the yeast uracil phosphoribosyltransferase (YUPRT) gene.RESULTS: In vitro stably transduced Morris rat hepatoma cells (MH) expressing the bifunctional SuperCD suicide gene (MH SuperCD) showed a clearly marked enhancement in cell killing when incubated with 5-FC as compared with MH ceils stably expressing YCD solely (MH YCD) or the cytosine deaminase gene of bacterial origin(MH BCD), respectively. In vivo, MH SuperCD tumors implanted both subcutaneously as well as orthotopically into the livers of syngeneic ACI rats demonstrated significant tumor regressions (P<0.01) under both high dose as well as low dose systemic 5-FC application,whereas MH tumors without transgene expression (MH naive) showed rapid progression. For the first time, an order of in vivo suicide gene effectiveness (SuperCD>>YCD > > BCD > > > negative control) was defi ned as a result of a directin vivo comparison of all three suicide genes.CONCLUSION: Bifunctional SuperCD suicide gene expression is highly effective in a rat hepatoma model,thereby significantly improving both the therapeutic index and the efficacy of hepatocellular carcinoma killing by fluorocytosine.Florian Graepler Marie-Luise Lemken Wolfgang A Wybranietz Ulrike Schmidt Irina Smirnow Christine D GroB Martin Spiegel Andrea Schenk Schenk Hansj(o|¨)rg Graf Ulrike A Lauer Reinhard Vonthein Michael Gregor Sorin Armeanu Michael Bitzer Ulrich M.Lauer 2005World Journal of Gastroenterology2005,11,44:2
4CVT夹紧系统优化显示文摘本文详细讨论了对能量损失起主要影响的两个部件。分析了在液压控制中产生的能量损失以及进一步减少损失的可能性。以及变速装置中由于夹紧力产生的机械损。Hartmut Faust Manfred Homm Franz Bitzer 2004传动技术2004,18,4:2
5Smad proteins and transforming growth factor-beta signaling显示文摘Schiffer M von Gersdorff G Bitzer M 2000Kidney Int Suppl2000,77,25:1
6Defocus-indueed changes in ZENK expression in the chicken retina 显示文摘Bitzer M Schaeffel F 2002Invest Ophthalmol Vis Sci2002,43,1:1
7Depression and anxietyduring pregnancy: A risk fac- tor for obstetric, fetal and neonatal out- come? A critical review of the literature 显示文摘Alder J Fink N Bitzer J 2007J Matern Fetal Neonatal Med2007,20,3:1
8Synchronous gastrointestinal and musculoskeletal manifestations of different subtypes of inflammatory myofibroblastic tumor :CT, MRI and pathological fea- tures显示文摘HORGER M PFANNENBERG C BITZER M 2005Eur Radiol2005,15,:1
9Diagnosis of and Therapy for Hepatocellular Carcinoma显示文摘T. Greten N. Malek S. Schmidt J. Arends P. Bartenstein W. Bechstein T. Bernatik M. Bitzer A. Chavan M. Dollinger D. Domagk O. Drognitz M. Düx S. Farkas G. Folprecht P. Galle M. Gei?ler G. Gerken D. Habermehl T. Helmberger K. Herfarth R. Hoffmann M. Holtma 2013Z Gastroenterol2013,,11:1
10Association between NAD(P)H: quinone oxidoreductase 1 (NQ01) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract显示文摘Sarbia M Bitzer M Siegel D 2003Int J Cancer2003,107,3:1
11A dual-frequency Wilkinson power divider: For a frequency and its first harmonic 显示文摘Wu L Yilmaz H Bitzer T 2005IEEE Microwave and Wireless Components Letters2005,5,2:1
12Pneumonia:incidence,risk factors,and outcome in injured patients 显示文摘Rodriguez JL Gibbons KJ Bitzer LG 1991J Trauma1991,31,7:1
13Synchronous gas-trointestinai and musculoskeletal manifestations of different sub-types of inflammatory myofibroblastic tumor:CT, MRI and pathological fea- tures显示文摘HORGER M PFANNENBERG C BITZER M 2005Eur Radiol2005,15,:1
14Oral contraceptives in adolescent women 显示文摘Bitzer J 2013Best Pract Res Clin Endocrinol Metab2013,27,1:1
15The importance of pial blood supply to the development of peritumoral brain edema in meningiomas显示文摘Bitzer M Lars W Andreas R 1997J Neurosurg1997,87,:1
16Does foreign direct investment transfer technology across borders? New evidence显示文摘Jürgen Bitzer Monika Kerekes 2008Economics Letters2008,,3:1
17Experiment-driven electrochemical modeling and systematic parameterization for a lithium-ion battery cell显示文摘Schmidt Alexander P Bitzer Matthias Imre Arpad W 2010Journal of Power Sources2010,195,15:1
18Visually induced changes in components of the retinoic acid system in fundal layers of the chick显示文摘Bitzer M Feldkaemper M Schaeffel F 2000Exp Eye Res2000,70,:1
19Visually induced changes in components of the retinoid acid system in fundal layers of the chick显示文摘 Feldkaemper M Schaeffel F 2000Exp Eye Res2000,70,1:1
20The effects of a small-dose naloxone infusion on opioid-induced side effects and analgesia in children and adolescents treated with intra- venous patient-controlled analgesia: a double-blind, pro- spective, randomized, controlled study 显示文摘Maxwell LG Kaufmann SC Bitzer S 2005Anesth Analg2005,100,4:1
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