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| 1 | 863 genomes reveal the origin and domestication of chicken显示文摘Despite the substantial role that chickens have played in human societies across the world,both the geographic and temporal origins of their domestication remain controversial.To address this issue,we analyzed 863 genomes from a worldwide sampling of chickens and representatives of all four species of wild jungle fowl and each of the five subspecies of red jungle fowl(RJF).Our study suggests that domestic chickens were initially derived from the RJF subspecies Gallus gallus spadiceus whose present-day distribution is predominantly in southwestern China,northern Thailand and Myanmar.Following their domestication,chickens were translocated across Southeast and South Asia where they interbred locally with both RJF subspecies and other jungle fowl species.In addition,our results show that the White Leghorn chicken breed possesses a mosaic of divergent ancestries inherited from other subspecies of RJF.Despite the strong episodic gene flow from geographically divergent lineages of jungle fowls,our analyses show that domestic chickens undergo genetic adaptations that underlie their unique behavioral,morphological and reproductive traits.Our study provides novel insights into the evolutionary history of domestic chickens and a valuable resource to facilitate ongoing genetic and functional investigations of the world's most numerous domestic animal. | Ming-Shan Wang Mukesh Thakur Min-Sheng Peng Yu Jiang Laurent Alain Francois Frantz Ming Li Jin-Jin Zhang Sheng Wang Joris Peters Newton Otieno Otecko Chatmongkon Suwannapoom Xing Guo Zhu-Qing Zheng Ali Esmailizadeh Nalini Yasoda Hirimuthugoda Hidayat Ashari Sri Suladari Moch Syamsul Arifin Zein Szilvia Kusza Saeed Sohrabi Hamed Kharrati-Koopaee Quan-Kuan Shen Lin Zeng Min-Min Yang Ya-Jiang Wu Xing-Yan Yang Xue-Mei Lu Xin-Zheng Jia Qing-Hua Nie Susan Joy Lamont Emiliano Lasagna Simone Ceccobelli Humpita Gamaralalage Thilini Nisanka Gunwardana Thilina Madusanka Senasige Shao-Hong Feng Jing-Fang Si Hao Zhang Jie-Qiong Jin Ming-Li Li Yan-Hu Liu Hong-Man Chen Cheng Ma Shan-Shan Dai Abul Kashem Fazlul Haque Bhuiyan Muhammad Sajjad Khan Gamamada Liyanage Lalanie Pradeepa Silva Thi-Thuy Le Okeyo Ally Mwai Mohamed Nawaz Mohamed Ibrahim Megan Supple Beth Shapiro Olivier Hanotte Guojie Zhang Greger Larson Jian-Lin Han Dong-Dong Wu Ya-Ping Zhang | 2020 | Cell Research2020，30，8： | 7 |
| 2 | Peer Instruction:A Teaching Method to Foster Deep Understanding显示文摘 | Beth Simon Quintin Cutts | 2012 | Communications of the ACM2012，55，2： | 1 |
| 3 | Paradoxical partners: Electronic communication and electronic democracy显示文摘 | Beth Simone Noveck | 2000 | Democratization2000，，1： | 1 |
| 4 | Dysfunctional CD39POS regulatory T cells and aberrant control of T‐helper type 17 cells in autoimmune hepatitis显示文摘 | Charlotte R. Grant Rodrigo Liberal Beth S. Holder John Cardone Yun Ma Simon C. Robson Giorgina Mieli‐Vergani Diego Vergani Maria Serena Longhi | 2014 | Hepatology2014，，： | 1 |
| 5 | The Open Provenance Model core specification (v1.1)显示文摘 | Luc Moreau Ben Clifford Juliana Freire Joe Futrelle Yolanda Gil Paul Groth Natalia Kwasnikowska Simon Miles Paolo Missier Jim Myers Beth Plale Yogesh Simmhan Eric Stephan Jan Van den Bussche | 2010 | Future Generation Computer Systems2010，，： | 1 |
| 6 | Inhibition of Interleukin-17 Promotes Differentiation of CD25 – Cells Into Stable T Regulatory Cells in Patients With Autoimmune Hepatitis显示文摘 | Maria Serena Longhi Rodrigo Liberal Beth Holder Simon C. Robson Yun Ma Giorgina Mieli–Vergani Diego Vergani | 2012 | Gastroenterology2012，，7： | 1 |
| 7 | 'Peer to Patent' : Collective Intelligenc, Open Review, and Patent Reform 显示文摘 | Beth Simone Noveck | 2006 | Harvard Journal of Law and Technology2006，20，1： | 1 |
| 8 | ' Peer to Patent' : Collective Intelligenc,Open Review, and Patent Reform显示文摘 | Beth Simone Noveck | 2006 | Harvard Journal of Law and Technology2006，20，1： | 1 |
| 9 | 'Peer to Patent' : Collective Intelligenc, Open Review and Patent Reform 显示文摘 | Beth Simone Noveck | 2006 | Harvard Journal of Law and Technology2006，20，1： | 1 |
| 10 | A Randomized Controlled Trial of Catheter Ablation Versus Medical Treatment of Atrial Fibrillation in Heart Failure (The CAMTAF Trial)显示文摘 | Ross J. Hunter Thomas J. Berriman Ihab Diab Ravindu Kamdar Laura Richmond Victoria Baker Farai Goromonzi Vinit Sawhney Edward Duncan Stephen P. Page Waqas Ullah Beth Unsworth Jamil Mayet Mehul Dhinoja Mark J. Earley Simon Sporton Richard J. Schilling | 2014 | Circulation: Arrhythmia and Electrophysiology2014，，1： | 1 |
| 11 | The Electronic Revolution inRulemaking 显示文摘 | BETH SIMONE NOVECK | 2004 | Emory Law Journal2004，，53： | 1 |
| 12 | 实验员如何提高学校科学教育质量——以英格兰一个小规模研究为例显示文摘介绍了英格兰的7所学校如何通过关注实验员的专业发展来提高科学教育质量。2013年9月,为了提高高中实验员的技术服务水平,盖茨比慈善基金会资助英国国家科学学习中心主持开展了一个让高中实验员和有经验的高级实验员一起合作设计实践的项目。项目为每所学校提供2000英镑的资金,资金的使用主要受一个校外的导师监督。项目的效果可以直接在课堂中体现,如教师更加自信、学生获得了更加多样和更高质量的实践经历。项目显示,如果学校希望提高科学教学质量,在实验员专业发展上的少量投资即可以获得很显著的效果。 | 李巧红 Beth Jones Simon Quinnell | 2016 | 教育与装备研究2016，32，3： | 0 |
| 13 | Mechanistic insights into the key marine dimethylsulfoniopropionate synthesis enzyme DsyB/DSYB显示文摘Marine algae and bacteria produce approximately eight billion tonnes of the organosulfur molecule dimethylsulfoniopropionate(DMSP)in Earth's surface oceans annually.DMSP is an antistress compound and,once released into the environment,a major nutrient,signaling molecule,and source of climate-active gases.The methionine transamination pathway for DMSP synthesis is used by most known DMSP-producing algae and bacteria.The S-directed S-adenosylmethionine(SAM)-dependent 4-methylthio-2-hydroxybutyrate(MTHB)S-methyltransferase,encoded by the dsyB/DSYB gene,is the key enzyme of this pathway,generating S-adenosylhomocysteine(SAH)and 4-dimethylsulfonio-2-hydroxybutyrate(DMSHB).DsyB/DSYB,present in most haptophyte and dinoflagellate algae with the highest known intracellular DMSP concentrations,is shown to be far more abundant and transcribed in marine environments than any other known S-methyltransferase gene in DMSP synthesis pathways.Furthermore,we demonstrate in vitro activity of the bacterial DsyB enzyme from Nisaea denitrificans and provide its crystal structure in complex with SAM and SAH-MTHB,which together provide the first important mechanistic insights into a DMSP synthesis enzyme.Structural and mutational analyses imply that DsyB adopts a proximity and desolvation mechanism for the methyl transfer reaction.Sequence analysis suggests that this mechanism may be common to all bacterial DsyB enzymes and also,importantly,eukaryotic DSYB enzymes from e.g.,algae that are the major DMSP producers in Earth's surface oceans. | Chun-Yang Li Jason C.Crack Simone Newton-Payne Andrew R.J.Murphy Xiu-Lan Chen Benjamin J.Pinchbeck Shun Zhou Beth T.Williams Ming Peng Xiao-Hua Zhang Yin Chen Nick E.Le Brun Jonathan D.Todd Yu-Zhong Zhang | 2022 | mLife2022，1，2： | 0 |
| 14 | Author Correction:863 genomes reveal the origin and domestication of chicken显示文摘We apologize for a mistake in Fig.2 that was immediately identified by Edward McClure in our article published online on June 25,2020.In the labels of Fig.2a,b,the blue color should represent West Asian chickens while the brown color should depict South Asian chickens.The correct version of Fig.2 is shown below.This correction does not affect the description and conclusion of this article. | Ming-Shan Wang Mukesh Thakur Min-Sheng Pen Yu Jiang Laurent Alain Francois Frantz Ming Li Jin-Jin Zhang Sheng Wang Joris Peters Newton Otieno Otecko Chatmongkon Suwannapoom Xing Guo Zhu-Qing Zheng Ali Esmailizadeh Nalini Yasoda Hirimuthugoda Hidayat Ashari Sri Suladari Moch Syamsul Arifin Zein Szilvia Kusza Saeed Sohrabi Hamed Kharrati-Koopaee Quan-Kuan She Lin Zeng Min-Min Yang Ya-Jiang Wu Xing-Yan Yang Xue-Mei Lu Xin-Zheng Jia Qing-Hua Nie Susan Joy Lamont Emiliano Lasagna Simone Ceccobelli Humpita Gamaralalage Thilini Nisanka Gunwardana Thilina Madusanka Senasige Shao-Hong Feng Jing-Fang Si Hao Zhang Jie-Qiong Jin Ming-Li Li Yan-Hu Liu Hong-Man Chen Cheng Ma Shan-Shan Dai Abul Kashem Fazlul Haque Bhuiyan Muhammad Sajjad Khan Gamamad Liyanage Lalanie Pradeepa Silva Thi-Thuy Le Okeyo Ally Mwai Mohamed Nawaz Mohamed Ibrahim Megan Supple Beth Shapiro Olivier Hanotte Guojie Zhang Greger Larson Jian-Lin Han Dong-Dong Wu Ya-Ping Zhang | 2020 | Cell Research2020，30，9： | 0 |
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